Fungal Pathogens: Emerging Threats and Future Challenges (A1)
January 12-15, 2026  | Beaver Run Conference Center, Breckenridge, CO, United States
Scott G Filler, Rebecca Drummond and Iliyan D Iliev
Scholarship Deadline: Sep. 17, 2025 | Abstract Deadline: Dec. 23, 2025 | Early Registration Deadline: Nov. 14, 2025
* Session Chair † Invited but not yet accepted | Program current as of January 5, 2026 1 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, January 12, 2026
4:00–8:00 PM Registration Colorado Ballroom Foyer
6:00–8:00 PM Welcome Mixer Colorado Ballroom Foyer
Tuesday, January 13, 2026
7:00–8:00 AM Breakfast Summit Gallery
8:00–8:10 AM Welcome Remarks Peak 4-5
8:10–9:00 AM Keynote Address Peak 4-5
  * Scott G Filler, Lundquist Institute
Session Chair
 
  Anita Sil, University of California, San Francisco
Regulation of Coccidioides Virulence
 
9:00–11:15 PM Infections Caused by Airborne Fungal Pathogens Peak 4-5
  * Vincent M Bruno, University of Maryland School of Medicine
Session Chair
 
  Scott G Filler, Lundquist Institute
Identification of Oral Epithelial Cell Targets of Candida albicans
 
  Georgios Chamilos, University of Crete
Metabolic Interplay Between Macrophages and Rhizopus
 
  Bruce S Klein, University of Wisconsin Madison
Pseudogymnoascus Destructans and White-Nose Syndrome of Bats
 
  Yao Yu, MSKCC
Short Talk: Lymphocyte- and GM-CSF-mediated Host Defense in Central Nervous System (CNS) Aspergillus Infection
 
9:30–9:50 AM Coffee Break Colorado Ballroom Foyer
11:15–1:00 PM Poster Setup Peaks 1 - 3
11:15–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Peaks 1 - 3
2:30–4:30 PM Symposia Spotlight 1 Peak 4-5
  * Kristie Goughenour, University of Michigan/Ann Arbor VA
Session Chair
 
  Patricia P Peterson, Duke University Medical Center
How the STRIPAK Complex Coordinates Genome Stability, Host Adaptation, and Virulence in Cryptococcus
 
  Shirli Cohen, University of Colorado Anschutz Medical Campus
Candida albicans Promotes Group B Streptococcal Vaginal Persistence and Pathogenesis
 
  Greg Whitehill, UCLA
Checkpoint Blockade Augments Coccidioides-Specific T Cell Responses
 
  Xin Li, UT Southwestern Medical Center
An Unexpected Fungal RNA Signal in Immunity
 
  Zanetta Chang, Washington University in St. Louis
Elucidating Dissemination of the Fungal Pathogen Cryptococcus neoformans Through Genetic Barcoding
 
  Martinna Bertolini, University of Pittsburgh
Candida Albicans Infection Triggers Progressive Remodeling of the Oral Epithelial Landscape
 
  Olivia W Hepworth, Columbia University Irving Medical Center
Selective Inhibition of Lung Epithelial Chemokine Secretion by Coccidioides posadasii Spherules
 
  Dominik Awad, University of Michigan
Mycobiome-Derived Metabolites Impact the Pancreatic Tumor Microenvironment
 
4:30–5:00 PM Coffee Available Colorado Ballroom Foyer
5:00–7:00 PM Fungal Commensalism and Pathogenesis: Consequences for the Host Peak 4-5
  * Kyla Ost, University of Colorado AMC
Session Chair
 
  Iliyan D Iliev, Weill-Cornell Medical College
Transkingdom Bacterial-Fungal Crosstalk in Modulation of Intestinal Inflammation
 
  Petra Bacher, University Kiel
T Cell-Mediated Immunity to Fungi in Inflammatory Bowel Diseases
 
  Julie Segre, NIH/NHGRI
Human Skin Mycobiome
 
  Hongyu Wu, National Institute of Allergy and Infectious Diseases (NIAID)
Short Talk: Fungal Secreted Asparaginase Drives Intestinal Tuft Cell Expansion
 
  Animesh Anand Mishra, UT Southwestern Medical Center
Short Talk: Metabolite–Carbon Source Interactions Regulate Candida Albicans Growth and Gastrointestinal Colonization
 
7:00–8:00 PM Social Hour with Dinner Peaks 1 - 3
7:30–10:00 PM Poster Session 1 Peaks 1 - 3
Wednesday, January 14, 2026
7:00–8:00 AM Breakfast Summit Gallery
8:00–8:45 AM Keynote Address Peak 4-5
  * Iliyan D Iliev, Weill-Cornell Medical College
Session Chair
 
  Gordon D. Brown, University of Exeter
C-Type Lectins – New Insights into Their Roles in Antimicrobial Immunity
 
8:45–11:00 AM Fungal Infections of the Brain Peak 4-5
  * Kirsten Nielsen, Virginia Tech
Session Chair
 
  * Mari L. Shinohara, Duke University
Session Chair
 
  Rebecca Drummond, University of Birmingham
Heterogeneity of Fungal and Host Responses in the Brain
 
  Sarah Beattie, University of Iowa
Elucidating Mechanisms of A. Fumigatus Cerebral Pathogenesis
 
  Angie Gelli, University of California, Davis
Mechanisms of CNS Invasion by Cryptococcus
 
  Michal A Olszewski, VA Medical Center & University of Michigan
Short Talk: Immunoregulatory Network Offsetting Inflammatory Damage in Cryptococcal Meningoencephalitis
 
9:15–9:35 AM Coffee Break Colorado Ballroom Foyer
9:35–9:40 AM Award Recipient Acknowledgement Peak 4-5
11:00–1:00 PM Poster Setup Peaks 1 - 3
11:00–2:15 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Peaks 1 - 3
2:15–3:15 PM Career Roundtable Peak 4-5
3:30–4:30 PM Panel of Program Officers Peak 4-5
  * Rebecca Drummond, University of Birmingham
Panel Moderator
 
  * Iliyan D Iliev, Weill-Cornell Medical College
Panel Moderator
 
  Dona Love, National Institutes of Health
Panelist
 
  Tamara McNealy, National Institutes of Health
Panelist
 
4:30–5:00 PM Coffee Available Colorado Ballroom Foyer
5:00–7:00 PM Fungal Colonization and Immunity of the Skin and Mucosa Peak 4-5
  * Brian M Peters, University of Tennessee Health Science Center
Session Chair
 
  Mark Gresnigt, Leibniz-HKI
Deciphering the Dysregulated Inflammatory Responses of (Recurrent) Vulvovaginal Candidiasis
 
  Daniel H Kaplan, University of Pittsburgh
Cutaneous Nonpeptidergic Neurons Sense Extracellular ATP to Augment Barrier Repair and C. Albicanshost Defense
 
  Salomé LeibundGut-Landmann, University of Zürich
Cutaneous Control of Malassezia
 
  Jian Miao, Harbor-UCLA Medical Center
Short Talk: Early-life Fungal Colonization Reveals Stage-specific Immune Regulation in the Oral Mucosa
 
  Owen Jensen, University of Colorado Anschutz
Short Talk: Mannose Binding Lectin Regulation of Candida albicans in the Small Intestine
 
7:00–8:00 PM Social Hour with Dinner Peaks 1 - 3
7:30–10:00 PM Poster Session 2 Peaks 1 - 3
Thursday, January 15, 2026
7:00–8:00 AM Breakfast Summit Gallery
8:00–8:45 AM Keynote Address Peak 4-5
  * Rebecca Drummond, University of Birmingham
Session Chair
 
  Mihai G. Netea, Radboud University
Trained Immunity: From Bench to Bedside
 
8:45–11:00 AM Fungal Recognition and Antifungal Immunity Peak 4-5
  * Jatin Vyas, Columbia University
Session Chair
 
  Jay K Kolls, Tulane School of Medicine
Immunity to Pneumocystis
 
  Amariliz Rivera-Medina, Rutgers New Jersey Medical School
Innate Immune Response to Aspergillus Fumigatus
 
  Sarah L Gaffen, University of Pittsburgh
Type 17 Cell Cytokine Signaling and Coordination of Mucosal Fungal Immunity
 
  Michael J Boucher, Wadsworth Center, New York State Department of Health
Short Talk: Phenotypic Landscape of an Invasive Fungal Pathogen Reveals Its Unique Biology
 
9:15–9:35 AM Coffee Break Colorado Ballroom Foyer
11:00–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Late Breaking Research Presentation Chosen from Abstracts Peak 4-5
  * Bing Zhai, Shenzhen Institutes of Advanced Technology
Session Chair
 
  Katherine Doss, Dartmouth College
Surprising Strain-Specific Molecular Determinants of Aspergillus Fumigatus Pathogenicity Revealed by New Cancer Small Molecule Therapies
 
  Darin Wiesner, Rutgers - New Jersey Medical School
Early Spatial Dynamics of Neutrophil Recruitment in Lung Barrier Immunity to Coccidioides Infection
 
  Jazmin Reyes Servin, UC Merced
Interferon (IFN) beta Mediates Differential Type I IFN Signaling Regulation of Clearance and Damage During Aspergillus fumigatus (A. fumigatus) Infection
 
  Lucas dos Santos Dias, NIAID/NIH
CXCR3 Promotes T cell Recruitment and IFN-γ production and Drives Mucosal Candidiasis in Aire-Deficient Mice
 
  Amy L Seufert, University of Colorado Anschutz Medical Campus
T Cell-intrinsic Nod2 Regulation of Anti-fungal IL-17A and IL-17F
 
  Jonah Propp, University of Iowa
Discovery and Structural Insight into Novel Acetyl-CoA Synthetase Inhibitors for Antifungal Development
 
4:30–5:00 PM Coffee Available Colorado Ballroom Foyer
5:00–6:45 PM Challenges and Opportunities in Translational and Clinical Mycology Peak 4-5
  * Michail S Lionakis, NIAID, NIH
Session Chair
 
  David Andes, University of Wisconsin
New Antifungal Drugs
 
  Kieren Marr, Elion Therapeutics
Challenges of Antifungal Drug Development
 
  Marie-Claire Arrieta, University of Calgary
The Early-Life Mycobiome in Immune and Metabolic Development
 
  Bing Zhai, Shenzhen Institutes of Advanced Technology
Short Talk: Quantitative Dynamics of the Vaginal Mycobiome in Pregnancy
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Peak 4-5
7:00–8:00 PM Social Hour with Dinner Peaks 1 - 3
8:00–9:00 PM Entertainment Peaks 1 - 3
8:00–9:00 PM Cash Bar Peaks 1 - 3
Friday, January 16, 2026
12:00–11:59 PM Departure