Mitochondrial Biology in Health and Disease (A2)
January 13-16, 2025  | NTUH International Convention Center, Taipei, TPE, Taiwan
Lena Pernas, Anne N Murphy and Johan Auwerx
Scholarship Deadline: Oct. 16, 2024 | Abstract Deadline: Dec. 24, 2024 | Early Registration Deadline: Nov. 27, 2024
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 4 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, January 13, 2025
4:00–8:00 PM Registration 2nd Floor Foyer
6:00–8:00 PM Welcome Mixer 2nd Floor Foyer
Tuesday, January 14, 2025
7:30–8:30 AM Breakfast Individual Hotel
8:00–8:30 AM Poster Setup 2nd Floor Foyer
8:15–5:00 PM Poster Viewing 2nd Floor Foyer
8:30–9:30 AM Welcome and Keynote Address Room 201
  * Lena Pernas, University of California, Los Angeles and Max Planck Institute for Biology of Ageing
Session Chair
 
  Navdeep S Chandel, Northwestern University
Mitochondria are Signaling Organelles
 
9:30–11:45 AM Mitochondrial Signaling at Different Scales Room 201
  * Tania Catarina Medeiros, Max Planck Biology of Ageing
Session Chair
 
  Jodi Nunnari, Altos Labs
Mitochondria and Interorganellar Communication
 
  Jared Rutter, University of Utah
Mitochondrial Metabolic Messengers
 
  Sarah-Maria Fendt, VIB-KU Leuven
Metabolic Regulation of Metastasis Formation
 
10:00–10:20 AM Coffee Break 2nd Floor Foyer
11:45–12:45 PM Lunch Room 201
12:00–2:30 PM Poster Session 1 2nd Floor Foyer
2:30–4:30 PM Symposia Spotlight 1: Tissue-Specific Functions of Mitochondria Room 201
  * Ron Baik, Memorial Sloan Kettering/Weill Cornell Medicine
Characterizing the Dynamics of mtDNA Mutations in Human Retinal Pigment Epithelial (RPE) Cells
 
  Mariana Borsa, University of Oxford
DamAged Memories: How Mitochondrial Inheritance Controls T Cell Diversity
 
  Noritaka Yamaguchi, Chiba University
Mitochondrial Protein C15ORF48 is an Inducer of Thymo-autophagy that Regulates Immunotolerance
 
  Kao C Han, Academia Sinica
The Interplay between Purinosomes and Mitochondria (Cardiopathy)
 
  Jason Maynes, Hospital for Sick Children
Mitochondrial Dysfunction and Metabolic Therapies for Congenital Heart Disease
 
  Irit Adini, Harvard Medical School, Massachusetts General Hospital
Mitochondrial Transfer Between Melanocytes and Dendritic Cells: Unveiling a Crucial Pathway in Inflammatory Response
 
  Yen-Jung Hsu, National Taiwan University, College of Medicine
Roles of GSK3 Isoforms in Mitochondrial Quality Control of Skeletal Muscle
 
  Xiaojing Cuili, NTU
NME3 Catalytic Function Plays a Critical Role in the Maintenance of Cerebellar Function in an Age and Gender-Dependent Manner
 
4:30–5:00 PM Coffee Available 2nd Floor Foyer
5:00–7:00 PM Mitochondrial Import and Export Room 201
  Sarah Hassdenteufel, Weizmann Institute of Science
A Novel Approach for Higher throughput Screening at Ultrastructural Resolution - Uncovering Cristae Modulators in Human Mitochondria
 
  Lena Ho, Duke-NUS Medical School
EMBO Young Investigator Lecture: Regulation of Oxidative Metabolism by Mitochondrial Microproteins
 
  * Soni Deshwal, Helmholtz-Munich
Unveiling Pathways that Dictate Mitochondrial CoQ Export and Their Role in Ferroptosis
 
  Nora Kory, Harvard T.H Chan School of Public Health
Short Talk: TRANSIT – A New Approach to Identifying Mitochondrial Transporters
 
7:00–8:00 PM On Own for Dinner
Wednesday, January 15, 2025
7:30–8:30 AM Breakfast Individual Hotel
8:00–8:30 AM Poster Setup 2nd Floor Foyer
8:15–5:00 PM Poster Viewing 2nd Floor Foyer
8:30–11:30 AM Tissue-Specific Mitochondrial Dysfunction Room 201
  Ying Liu, Peking University
Pre-Recorded: Mitochondria in Intertissue Communication in Aging and Disease
 
  Aleksandra Filipovska, Harry Perkins Institute of Medical Research
Lipid-Mediated Organization of Mitochondrial Interactions in 3D
 
  * Aleksandra Trifunovic, University of Cologne
Taming Mitochondrial Stress Responses
 
  Chantell S Evans, Duke University School of Medicine
Mitochondrial Quality Control in the Nervous System
 
  Fabian Finger, University of Copenhagen
Short Talk: Mitochondrial Membrane Lipid CL Controls Fiber-type Adaptations in Aging Muscle via ERRγ
 
  Katsu Funai, University of Utah
Short Talk: Cardiolipin Deficiency Disrupts Electron Transport Chain to Induce Steatohepatitis
 
9:30–9:50 AM Coffee Break 2nd Floor Foyer
11:30–12:30 PM Lunch Room 201
12:00–2:30 PM Poster Session 2 2nd Floor Foyer
3:00–4:30 PM Career Roundtable Room 201
  Aleksandra Trifunovic, University of Cologne
Professor
 
  Shu-Jung Chang, National Taiwan University
Assistant Professor
 
  Marijn G Ford, Altos Labs
Principal Scientist
 
  Pin-Chao Liao, National Tsing Hua University
Assistant Professor
 
4:30–5:00 PM Coffee Available 2nd Floor Foyer
5:00–7:00 PM Mitochondria in Immunity and Infection Room 201
  Gerald S. Shadel, The Salk Institute for Biological Studies
Mitochondria are Genotoxic Sensors
 
  Ping-Chih Ho, Ludwig Institute for Cancer Research
Mitochondrial Catastrophes and T Cell Exhaustion: Lessons can be Applied in CAR T Cell Therapy
 
  * Lena Pernas, University of California, Los Angeles and Max Planck Institute for Biology of Ageing
'Mitochondria-Microbe Conflict
 
  Yasmine T Toudji, Vanderbilt University
Short Talk: Differential Adaptative Responses of T Cells to Mild Heat Stress
 
  Yentli E Soto Albrecht, University of Pennsylvania Perelman School of Medicine, Children's Hosp of Philadelphia
Short Talk: Mitochondrial OXPHOS Restricts SARS-CoV-2 Replication by Limiting Glycolytic Capacity
 
7:00–8:00 PM On Own for Dinner
Thursday, January 16, 2025
7:30–8:30 AM Breakfast Individual Hotel
8:30–11:30 AM Targeting Mitochondrial Disease Room 201
  Pénélope Andreux, Vandria SA
Mitophagy-Targeting Therapies
 
  Johan Auwerx, École Polytechnique Fédérale de Lausanne
Ceramide de novo Synthesis Links Degenerative Disorders with Mitochondrial and Protein Homeostasis
 
  * Luca Scorrano, University of Padova
Unbiased Screenings for Mitochondrial Membrane Contact Sites and Mitochondrial Fission Regulators
 
  Oliver Rackham, Curtin University
Short Talk: How a Cytoplasmic Protein Causes Mitochondrial Disease
 
  Sean P Curran, University of Southern California
Short Talk: RNA Editing in Response to Mitochondrial Dysfunction Drives Accelerated Aging
 
9:30–9:50 AM Coffee Break 2nd Floor Foyer
11:30–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Mitochondria from Bacteria to Endosymbiont Room 201
  Alexandre Smirnov, University of Strasbourg, CNRS
Ancestral Ribosome Assembly Mechanisms: From Bacteria to Mitochondria (and Beyond)
 
  * Cristiana Zollo, University of Cologne
The “Mitoscanner”: Endogenous DRP1 Continuously Scans Mitochondria in a Diffusive Manner Beyond the Fission Site
 
  Chieh-Ju Sung, National Taiwan University
Evolutionary Conservation of Cardiolipin Externalization in Stressed Mitochondrial Revealed by Novel Bio-probe
 
  Suzuka Ono, Kyoto Sangyo University
ATPases Control the Intracellular Distribution of Single-pass Membrane Proteins
 
  Sofia La Vecchia, Rutgers University
Targeting Mitochondrial Dynamics In Drug-Resistant Acute Leukemia
 
  N Sushma Sri, Dr. Reddy's Institute of Life Sciences
Mitochondrial Dysfunction Due to PISD Loss Leads to Skeletal Phenotypes in Spondyloepimetaphyseal Dysplasia
 
  Feng-Yung Wang, National Yang-Ming Chiao Tung University
Mitochondrial S-adenosylmethionine Deficiency Induces Mitochondrial Unfolded Protein Response and Extends Lifespan in Caenorhabditis Elegans
 
4:30–5:00 PM Coffee Available 2nd Floor Foyer
5:00–6:45 PM Non-Canonical Mitochondrial Compartments Room 201
  * Johannes M Herrmann, University of Kaiserslautern
Dysfunctional mitochondria trap proteins in the intermembrane space
 
  Samantha C. Lewis, University of California, Berkeley
Interdependencies Between Mitochondrial DNA and RNA Maintenance
 
  Julien Prudent, University of Cambridge
Inner mitochondrial membrane quality control and mtDNA regulation
 
  Naotada Ishihara, Osaka University
Short Talk: Dynamic Regulation of Mitochondrial Nucleoids by Inner-membrane Components and Proteins
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room 201
7:00–8:00 PM Social Hour with Lite Bites Room 201
Friday, January 17, 2025
12:00–11:59 PM Departure