Myeloid Cell Diversity: From Fundamental Biology to Disease States (A3)
January 28-31, 2024
| Fairmont Banff Springs, Banff, AB, Canada
Andrés Hidalgo, Daniela F. Quail and Lai Guan Ng
Scholarship Deadline: Oct. 24, 2023 | Abstract Deadline: Oct. 24, 2023 | Early Registration Deadline: Nov. 28, 2023
4:00–8:00 PM |
Arrival and Registration |
Van Horne Foyer |
6:00–8:00 PM |
Welcome Mixer |
Van Horne Foyer |
7:00–8:00 AM |
Breakfast |
Van Horne B/C |
8:00–9:00 AM |
Welcome and Keynote Address |
Van Horne A |
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Kodi S. Ravichandran, Washington University in St. Louis Phagocytosis of Dead Cells |
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9:00–11:15 AM |
Learning from Imaging |
Van Horne A |
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Milka Sarris, University of Cambridge Neutrophil Dynamics During Inflammatory Responses |
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Michael Sixt, Institute of Science and Technology Austria Principles of Myeloid Cell Dynamics |
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Thomas R O'Neil, Westmead Institute for Medical Research Short Talk: Short Talk: An in situ Quantitative Map of Mononuclear Phagocytes Across Inflamed and Uninflamed Human Mucosal Tissue Using High Parameter Imaging Platforms |
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Andrés Hidalgo, Yale School of Medicine Structural Neutrophils |
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9:30–9:50 AM |
Coffee Break |
Van Horne Foyer |
11:15–1:00 PM |
Poster Setup |
Van Horne B/C |
11:15–5:00 PM |
On Own for Lunch |
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1:00–10:00 PM |
Poster Viewing |
Van Horne B/C |
3:00–4:30 PM |
Career Roundtable |
Van Horne A |
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Dmitry I. Gabrilovich, AstraZeneca Executive Director, Chief Scientist, Cancer Immunology |
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Irina A. Udalova, University of Oxford Professor of Molecular Immunology |
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Ukpong Bassey Eyo, University of Virginia Associate Professor of Neuroscience |
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4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
5:00–7:00 PM |
Understanding Myelopoiesis |
Van Horne A |
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H. Leighton Grimes, Cincinnati Children's Hospital Medical Center Understanding Granulopoiesis |
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Daniel Lucas, Cincinnati Children's Medical Center Bone Marrow Myeloid Niches in Homeostasis and Stress |
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Irina A. Udalova, University of Oxford Transcriptional Regulation of Myelopoiesis |
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Hannah C. Garner, Netherlands Cancer Institute Short Talk: Short Talk: Understanding and Reversing Mammary Tumour-induced Inflammatory Myelopoiesis to Reduce Metastatic Spread |
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Quin Waterbury, Columbia University Irving Medical Center Short Talk: Short Talk: Neutrophils Play a Dual Role in Promoting Inflammation During Obesity |
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7:00–8:00 PM |
Social Hour with Lite Bites |
Van Horne B/C |
7:30–10:00 PM |
Poster Session 1 |
Van Horne B/C |
Tuesday, January 30, 2024
7:00–8:00 AM |
Breakfast |
Van Horne B/C |
8:00–11:00 AM |
Myeloid States Versus Subsets |
Van Horne A |
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Ido Amit, Weizmann Institute Metabolic Regulation by Myeloid Cells |
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Maziar Divangahi, McGill University Unlocking the Power of Trained Immunity in Pulmonary Infections |
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Alexander McGurk, Cornell University Short Talk: Short Talk: Monocytes and Th1s Cooperate to Build Perivascular Activation Niches that Optimize T Cell Function in Inflamed Tissues |
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Ivan Ballesteros, CNIC Short Talk: Short Talk: The NeuMap Reveals Confined but Remarkable Plasticity of the Entire Neutrophil Compartment |
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Tingting Huang, Shanghai jiaotong University School of Medicine Short Talk: Short Talk: Sialylation of CD177 Glycan on Neutrophils Combats Neuroinflammation against Acute Brain Injuries |
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9:00–9:20 AM |
Coffee Break |
Van Horne Foyer |
11:00–1:00 PM |
Poster Setup |
Van Horne B/C |
11:00–5:00 PM |
On Own for Lunch |
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1:00–10:00 PM |
Poster Viewing |
Van Horne B/C |
2:30–4:30 PM |
Workshop 1: Myeloid States: From Photons to Genes |
Van Horne A |
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Luke Brown, University of Calgary Immunothrombosis: A Determinant of Host Defence and Immunopathology during Sepsis |
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Thomas Daugbjerg Madsen, NIH/NCI Intravital Imaging of the Myeloid Immune Cell Landscape during the Initiation and Progression of Squamous Cell Carcinoma |
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Diletta Di Mitri, Humanitas University Unravelling the Role of Tumor Associated Macrophages in Resistance to Anti-cancer Therapies |
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Abigail Kathleen Grootveld, Garvan Institute of Medical Research Cellular Dynamics of Tingible Body Macrophages Locally Activated by Apoptotic Cells in the Germinal Centre |
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Roman Sankowski, University of Freiburg Unveiling the Impact of Hypoxia on Developmental and Pathological Responses in CNS Macrophages: Insights from a Multi-Omic Single-Cell Analysis |
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Warren Pear, University of Pennsylvania Trib1 Regulates Neutrophil Lifespan and Function |
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Nicole Sarden, University of Calgary A Polarized Neutrophil State Generated During Viral Pneumonia Controlled by Neural Responses |
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4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
5:00–7:00 PM |
Myeloid Cells in Disease and Aging |
Van Horne A |
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Ukpong Bassey Eyo, University of Virginia Microgia Control of Brain Function |
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Andrea L. Graham, Princeton University Myeloid Cells Under the Prism of Ecology |
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Christina J. Camell, University of Minnesota Myeloid Cells as Drivers of Aging |
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Dmitry I. Gabrilovich, AstraZeneca Immune Suppressive Granulocytes |
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Kai Mesa, New York University Short Talk: Short Talk: Niche-specific Macrophage Loss Promotes Skin Capillary Aging |
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7:00–8:00 PM |
Social Hour with Lite Bites |
Van Horne B/C |
7:30–10:00 PM |
Poster Session 2 |
Van Horne B/C |
Wednesday, January 31, 2024
7:00–8:00 AM |
Breakfast |
Van Horne B/C |
8:00–11:00 AM |
Lifestyle and Tumoral Immunity |
Van Horne A |
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Christine Carine Moussion, Genentech, Inc. Spatial Organization in the TME |
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Filip K. Swirski, Icahn School of Medicine at Mount Sinai Brain Control of Myeloid Function |
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Mikala Egeblad, Cold Spring Harbor Laboratory Stress-Induced Myeloid Activation and Cancer |
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Daniela F. Quail, McGill University Myeloid Cells During Obesity-Driven Disease |
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Simon Milette, McGill University Short Talk: Short Talk: Circadian Control of Neutrophil Extracellular Trap Formation Temporally
Regulates Metastatic Lung Cancer Progression |
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9:00–9:20 AM |
Coffee Break |
Van Horne Foyer |
11:00–5:00 PM |
On Own for Lunch |
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2:30–4:30 PM |
Workshop 2: Connecting Metabolism and Lifestyle |
Van Horne A |
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Ada Weinstock, University of Chicago Weight Loss-induced Macrophages Promote Resolution of Atherosclerosis |
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Stefanie K Wculek, IRB Barcelona Mitochondrial Metabolism Regulates the Immunogenic Responsiveness of Dendritic Cells |
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Zhenyu Zhong, The University of Texas Southwestern Medical Center Obesity Rewires Macrophage Nucleotide Metabolism to License NLRP3 Inflammasome Hyperactivation and Disease Development |
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Farzana Bhuyan, National Institutes of Health( MSc) Dysferlin Mediated Membrane Dysregulation in Monocytes and Macrophages Drives an IL-1 Mediated Autoinflammatory Disease |
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Justin S. A. Perry, Memorial Sloan Kettering Cancer Center Early Life High Fructose Exposure Disrupts Microglia Function and Impedes Neurodevelopment |
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Siu Ling (Christine) Wong, Nanyang Technological University Singapore Sirtuin 1 Activation by Resveratrol Revitalizes the endogenous NETosis “Brake” in Diabetes |
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4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
5:00–6:45 PM |
Myeloid Metabolism and Immunotherapy |
Van Horne A |
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Lai Guan Ng, Shanghai Immune Therapy Institute Remote Presentation: Immune Dynamics in the Marrow |
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Renato Ostuni, Ospedale San Raffaele S.r.l. Transcriptional Control of Tumor-Associated Macrophages |
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Leila Akkari, Netherlands Cancer Institute Macrophages as Regulators of Tumor Metabolism |
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Oakley C. Olson, Memorial Sloan-Kettering Cancer Center Short Talk: Short Talk: Targeting Hematopoietic Glutaminolysis Impairs Emergency Myelopoiesis and Breast Cancer Progression |
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6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Van Horne A |
7:00–8:00 PM |
Social Hour with Lite Bites |
Van Horne B/C |
8:00–9:00 PM |
Trivia! |
Van Horne A |
Thursday, February 1, 2024