B Cell and Antibody Responses (B1)
February 8-11, 2027  | Mercure London Earls Court, London, United Kingdom
Gabriel D Victora, Pia Dosenovic and Andrea Reboldi
Scholarship Deadline: Oct. 14, 2026 | Abstract Deadline: Jan. 19, 2027 | Early Registration Deadline: Dec. 10, 2026
* Session Chair † Invited but not yet accepted | Program current as of February 25, 2026 2 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, February 8, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, February 9, 2027
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–8:40 AM Welcome Remarks
8:40–9:30 AM Keynote Address
  Facundo D. Batista, Massachusetts Institute of Technology and Harvard University
B Cell Responses to Optimized Vaccine Antigens
 
9:30–11:45 AM B Cell Memory and Immune Longevity
  Tal I Arnon, Oxford University
Plasma Cell Differentiation in Inflammatory Niches in the Lung
 
  Hai Qi, Tsinghua University
Heterogeneity and Longevity of Plasma Cells
 
  Sarah F Andrews, National Institutes of Health
Early Life Imprinted Long Lived Memory B Cells
 
  Short Talk(s) Chosen from Abstracts
 
10:00–10:20 AM Coffee Break
11:45–12:45 PM Lunch
12:30–2:30 PM Posters
2:30–4:30 PM Symposia Spotlight 1: Basics of B Cell Biology
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Antibody-Antigen Interactions
  Christopher O Barnes, Stanford University
Talk Title to be Announced
 
  Stephen J. Elledge, Harvard Medical School
Mechanisms of Immunodominance
 
  Gunilla B. Karlsson Hedestam, Karolinska Institutet
Impact of Germline-Encoded Variations in Antibody Genes for Epitope Recognition
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM On Own for Dinner
Wednesday, February 10, 2027
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–11:30 AM B Cells at the Barriers
  Andrea Reboldi, University of Massachusetts Chan Medical School
Metabolic Regulation of Intestinal IgA Response
 
  Menna R Clatworthy, University of Cambridge
B Cells in the Brain
 
  Ashley Moseman, Duke University School of Medicine
Humoral Immune Implications at the Brain: Upper Respiratory Interface
 
  Jennifer L. Gommerman, University of Toronto
B Cell Responses at the Mucosal Surface
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Lunch
12:30–2:30 PM Posters
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Antibody Responses to Infection and Vaccination
  Eunice Wambui Nduati, KEMRI, Wellcome Trust
Germline Approaches
 
  Pamela J Bjorkman, California Institute of Technology
Vaccine Design to Elicit Broadly Protective Immune Responses against Potential Animal Spillover Viruses
 
  Pia Dosenovic, Karolinska Institutet
Regulation of B Cell Responses during Vaccination
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
Thursday, February 11, 2027
7:30–8:30 AM Breakfast
8:30–11:30 AM The Germinal Center Reaction
  Gabriel D Victora, Rockefeller University/HHMI
Clonal Dynamics of the Germinal Center Response
 
  Carola G Vinuesa, Francis Crick Institute
Germinal Centers in Autoimmune Disease
 
  Oliver Bannard, University of Oxford
Selection Processes in Germinal Centres
 
  Duane R Wesemann, Harvard Medical School
The Evolutionary Reach of Antibody Somatic Hypermutation
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Meet the Editors
12:30–1:30 PM Lunch
2:30–4:30 PM Symposia Spotlight 2: B Cells in Disease
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM B Cells in Disease
  Christopher C. Goodnow, Garvan Institute of Medical Research
Rogue Mutant B Cells in Autoimmunity
 
  Jamie M Orengo, Regeneron Pharmaceuticals Inc.
Antibodies in Allergic Diseases
 
  Fabian Müller, Friedrich-Alexander-University of Erlangen-Nürnberg
CART in B Cell Driven Autoimmune Diseases
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM On Own for Dinner
Friday, February 12, 2027
12:00–11:59 PM Departure