Cardiometabolism and Interorgan Crosstalk: Novel Mechanisms and Therapies (B2)
February 15-19, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Saptarsi M. Haldar, Karol E. Watson and David A Kass
Monday, February 15, 2027
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Tuesday, February 16, 2027
| 4:00–5:00 PM |
Welcome and Keynote Address |
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Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute
Mechanisms of Incretin Therapy and their CV and Neurological Benefits |
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| 5:00–7:00 PM |
Target Discovery and Patient Segmentation in Cardiometabolic Disease: AI and Human Genetics |
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Luca Lotta, Regeneron Pharmaceuticals Inc.
Human Genetics at the Intersection of Metabolism and CV Risk |
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Rajat Gupta, Massachusetts General Hospital
Functional Genomics and Perturbational Screening for Cardiometabolic Target Discovery |
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Anna Helgadottir †, Decode genetics
Metabolic Drivers of CVD and Implications for Clinical Trial Enrichment |
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Short Talk(s) Chosen from Abstracts
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Wednesday, February 17, 2027
| 8:00–11:00 AM |
Skeletal Muscle, Renal, and Vascular Crosstalk and CV Disease |
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Zoltan Arany, University of Pennsylvania
Rerouting Metabolic Fuel Flux Utilization across Organs in Cardiometabolic Disease |
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Flora Sam, Eli Lilly
Skeletal Muscle Myokines and HFpEF |
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Kristin I. Stanford, Ohio State University
Exercise, Adipose & Metabolic Crosstalk |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion: AI Tools in Cardiometabolic Research |
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| 12:00–1:00 PM |
Poster Setup |
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| 12:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Immune System Crosstalk in Cardiovascular and Metabolic Disease |
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Kory J. Lavine, Washington University School of Medicine
Single Cell Epigenomics to Reveal Cellular Crosstalk in CV Disease |
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Han Zhu, Stanford University
T Lymphocyte Subsets in Cardiovascular Homeostasis and Response to Cancer Immunotherapy |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Thursday, February 18, 2027
| 8:00–11:00 AM |
Emerging Cardiometabolic Therapeutics |
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William A. Chutkow †, Novartis Institute for Biomedical Research
Targeting Lean Muscle Mass in Cardiovascular and Metabolic Disease |
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Ambarish Pandey, UT Southwestern Medical Center
Heterogeneity in the Cardiovascular Benefits of GLP-1R Agonists: Identifying Treatment Responders Leveraging Novel Phenotyping and Data Science Approach |
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Speaker to be Announced
Novel Nucleic Acid-based Therapeutic Platforms in Cardiovascular and Metabolic Disease |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 11:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Nervous System Crosstalk in Cardiometabolic Disease |
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Daniela Carnevale, University La Sapienza in Rome
Heart-Brain-Splenic Axis and Control of Cardiovascular Disease |
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Filip K. Swirski, Icahn School of Medicine at Mount Sinai
Novel Immune/Neural Mechanisms in Cardiometabolic Disease |
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Clemence Blouet †, University of Cambridge
Central Mechanisms Underlying Synergistic Effects of Weight Loss Drugs |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Friday, February 19, 2027
| 8:00–11:00 PM |
Adiposity, Diabetes and Clinical CV Disease |
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David A Kass, Johns Hopkins Hospital
Obesity + HFpEF = Bad Sarcomeres |
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Karol E. Watson, University of California, Los Angeles
Novel Insights from the DPPOS Cohort |
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Saptarsi M. Haldar
Novel Approaches to Treating Obesity and Adiposity-Related Diseases |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 PM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:30–6:45 PM |
Novel Mechanisms of Liver, Adipose and Cardiovascular Crosstalk |
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Isha Jain, Arc Institute and Gladstone/UCSF
Hypoxic Signaling and Interorgan Crosstalk in Physiology & Disease |
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E. Dale Abel, David Geffen School of Medicine and UCLA Health
Insulin Signaling, Mitochondria and Metabolic Heart Disease |
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Katrin J. Svensson, Stanford University
Novel Peptides as Obesity Therapeutic Targets |
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Gabriele G Schiattarella, Charité University Medical Center
Cardiometabolic-Hepatic Crosstalk |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Saturday, February 20, 2027
