Cardiometabolism and Interorgan Crosstalk: Novel Mechanisms and Therapies (B2)
February 16-19, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Saptarsi M. Haldar, Karol E. Watson and David A Kass
Scholarship Deadline: Oct. 23, 2026 | Abstract Deadline: Jan. 27, 2027 | Early Registration Deadline: Dec. 18, 2026
Tuesday, February 16, 2027
| 1:00–6:00 PM |
Registration |
Colorado Ballroom Foyer |
| 3:00–3:10 PM |
Welcome Remarks |
Colorado Ballroom Peak 4-5 |
| 3:10–4:00 PM |
Keynote Address |
Colorado Ballroom Peak 4-5 |
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Daniel J. Drucker, Lunenfeld-Tanenbaum Research Institute
Mechanisms of Incretin Therapy and their CV and Neurological Benefits |
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| 4:00–6:00 PM |
Nervous System Crosstalk in Cardiometabolic Disease |
Colorado Ballroom Peak 4-5 |
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Ana Domingos, University of Oxford
Sympathetic Neural Circuits Burning Fat |
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Daniela Carnevale, University La Sapienza in Rome
Heart-Brain-Splenic Axis and Control of Cardiovascular Disease |
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Filip K. Swirski, Icahn School of Medicine at Mount Sinai
Novel Immune/Neural Mechanisms in Cardiometabolic Disease |
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Sophie M Steculorum, Max Planck Institute for Metabolism Research
Sensory Regulation of Metabolism |
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| 6:00–8:00 PM |
Welcome Mixer with Heavy Apps |
Colorado Ballroom Foyer |
Wednesday, February 17, 2027
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–11:00 AM |
Skeletal Muscle and Vascular Crosstalk and CV Disease |
Colorado Ballroom Peak 4-5 |
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Zoltan Arany, University of Pennsylvania
Rerouting Metabolic Fuel Flux Utilization across Organs in Cardiometabolic Disease |
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Flora Sam, Eli Lilly
Skeletal Muscle Myokines and HFpEF |
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Kristin I. Stanford, Ohio State University
Exercise, Adipose & Metabolic Crosstalk |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Colorado Ballroom Foyer |
| 11:10–12:10 PM |
Panel Discussion: AI Tools in Cardiometabolic Research |
Colorado Ballroom Peak 4-5 |
| 12:10–1:00 PM |
Poster Setup |
Colorado Ballroom Peak 1-3 |
| 12:10–3:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Colorado Ballroom Peak 1-3 |
| 3:00–4:30 PM |
Career Roundtable |
Colorado Ballroom Peak 4-5 |
| 4:30–5:00 PM |
Coffee Available |
Colorado Ballroom Foyer |
| 5:00–7:00 PM |
Immune-Renal-Cardiac Crosstalk |
Colorado Ballroom Peak 4-5 |
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Kory J. Lavine, Washington University School of Medicine
Single Cell Epigenomics to Reveal Cellular Crosstalk in CV Disease |
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Pilar Alcaide, University of Miami - Miller School of Medicine
T Cells Modulation of Cardiac Stiffening in Cardiometabolic HFpEF |
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Susmita Sahoo, Icahn School of Medicine at Mount Sinai
Kidney-to-Heart Communication: Kidney-Derived EV-miRNAs as A Diagnostic Tool for Subclinical Heart Disease in CKD |
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Han Zhu, Stanford University
T Lymphocyte Subsets in Cardiovascular Homeostasis and Response to Cancer Immunotherapy |
|
| 7:00–8:00 PM |
Social Hour with Dinner |
Summit Gallery |
| 7:30–10:00 PM |
Poster Session 1 |
Colorado Ballroom Peak 1-3 |
Thursday, February 18, 2027
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–11:00 AM |
Emerging Cardiometabolic Therapeutics |
Colorado Ballroom Peak 4-5 |
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William A. Chutkow, Novartis Institute for Biomedical Research
Targeting Lean Muscle Mass in Cardiovascular and Metabolic Disease |
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Ambarish Pandey, UT Southwestern Medical Center
Heterogeneity in the Cardiovascular Benefits of GLP-1R Agonists: Identifying Treatment Responders Leveraging Novel Phenotyping and Data Science Approach |
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Jori Chambers, Souffle Therapeutics
Myocyte Selective Gene Silencing for the Treatment of Heart Disease |
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Short Talk(s) Chosen from Abstracts
|
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| 9:00–9:20 AM |
Coffee Break |
Colorado Ballroom Foyer |
| 9:20–9:25 AM |
Award Recipient Acknowledgement |
Colorado Ballroom Peak 4-5 |
| 11:00–1:00 PM |
Poster Setup |
Colorado Ballroom Peak 1-3 |
| 11:00–2:30 PM |
On Own for Lunch |
|
| 11:00–10:00 PM |
Poster Viewing |
Colorado Ballroom Peak 1-3 |
| 2:30–4:30 PM |
Symposia Spotlight 1 |
Colorado Ballroom Peak 4-5 |
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Short Talks Chosen from Abstracts
|
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| 4:30–5:00 PM |
Coffee Available |
Colorado Ballroom Foyer |
| 5:00–7:00 PM |
Target Discovery and Patient Segmentation in Cardiometabolic Disease: AI and Human Genetics |
Colorado Ballroom Peak 4-5 |
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Luca Lotta, Regeneron Pharmaceuticals Inc.
Human Genetics at the Intersection of Metabolism and CV Risk |
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Rajat Gupta, Massachusetts General Hospital
Functional Genomics and Perturbational Screening for Cardiometabolic Target Discovery |
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Anna Helgadottir, deCODE genetics
Metabolic Drivers of CVD and Implications for Clinical Trial Enrichment |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
Summit Gallery |
| 7:30–10:00 PM |
Poster Session 2 |
Colorado Ballroom Peak 1-3 |
Friday, February 19, 2027
| 7:00–8:00 PM |
Breakfast |
Summit Gallery |
| 8:00–11:00 PM |
Adiposity, Diabetes and Clinical CV Disease |
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David A Kass, Johns Hopkins Hospital
Obesity + HFpEF = Bad Sarcomeres |
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Karol E. Watson, University of California, Los Angeles
Novel Insights from the DPPOS Cohort |
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Saptarsi M. Haldar, Genentech / Roche
Novel Approaches to Treating Obesity and Adiposity-Related Diseases |
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Short Talk(s) Chosen from Abstracts
|
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| 9:00–9:20 PM |
Coffee Break |
Colorado Ballroom Foyer |
| 11:00–2:30 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2 |
|
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
Colorado Ballroom Foyer |
| 5:00–7:00 PM |
Novel Mechanisms of Liver, Adipose and Cardiovascular Crosstalk |
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Isha Jain, Arc Institute and Gladstone/UCSF
Hypoxic Signaling and Interorgan Crosstalk in Physiology & Disease |
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E. Dale Abel, David Geffen School of Medicine and UCLA Health
Insulin Signaling, Mitochondria and Metabolic Heart Disease |
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Katrin J. Svensson, Stanford University
Novel Peptides as Obesity Therapeutic Targets |
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Gabriele G Schiattarella, Charité University Medical Center
Cardiometabolic-Hepatic Crosstalk |
|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Colorado Ballroom Peak 4-5 |
| 7:00–8:00 PM |
Social Hour with Dinner |
Summit Gallery |
| 8:00–9:00 PM |
Cash Bar |
Colorado Ballroom Peak 1-3 |
| 8:00–9:00 PM |
Entertainment |
Colorado Ballroom Peak 1-3 |
Saturday, February 20, 2027
