| 4:00–8:00 PM | Registration |
| 6:00–8:00 PM | Welcome Mixer |
| 7:30–8:30 AM | Breakfast |
| 8:00–8:30 AM | Poster Setup |
| 8:15–5:00 PM | Poster Viewing |
| 8:30–9:30 AM | Welcome and Keynote Address |
| Joanna Wysocka, Stanford University Epigenetic Regulators in Development and Disease |
| 9:30–11:45 AM | Chromatin Regulatory Mechanisms Governing Cell Fate in Health and Disease |
| Robert J. Klose, University of Oxford Understanding how CpG Island regulate Gene Expression |
| Anja Groth, University of Copenhagen Maintaining Cell Fate through Replication |
| Karim-Jean Armache, New York University Grossman School of Medicine Structure and Function of Epigenetic Complexes: Basic and Disease Mechanisms |
| Scott A. Armstrong, Dana-Farber Cancer Institute Mechanisms of Menin Inhibitor Sensitivity and Resistance |
| Short Talk(s) Chosen from Abstracts |
| 10:00–10:20 AM | Coffee Break |
| 11:45–12:45 PM | Lunch |
| 12:30–2:30 PM | Poster Session 1 |
| 2:30–4:30 PM | Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available |
| 5:00–7:00 PM | Therapeutic Opportunities Informed by Genetic Disruption of Chromatin Factors |
| Cigall Kadoch, Dana-Farber Cancer Institute, Harvard Medical School Structure and Function of Chromatin Remodeling Complexes in Human Disease: From Basic Mechanisms to Therapeutic Opportunities |
| Nicolas H Thomä, EPFL Lausanne Structural Basis of Transcription Factors and Protein Degradation |
| Isaac A. Klein, Dewpoint Therapeutics Targeting Transcription via Condensate Disruption |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | On Own for Dinner |
| 7:30–8:30 AM | Breakfast |
| 8:00–8:30 AM | Poster Setup |
| 8:15–5:00 PM | Poster Viewing |
| 8:30–11:30 AM | Novel Target Identification and Chemical Approaches |
| Tom W. Muir, Princeton University New Chemical Approaches to Reveal and Understand Chromatin Mechanisms |
| Ho Man Chan, AstraZeneca Targeting Methyltransferases and Other Epigenetic Factors with Small Molecules |
| Alessio Ciulli, University of Dundee, School of Life Sciences New Approaches Toward Chemical Degradation of Chromatin Machinery |
| Steven F Bellon, Foghorn Therapeutics Pharmacologic Disruption of Chromatin Regulatory Factors |
| Short Talk(s) Chosen from Abstracts |
| 9:30–9:50 AM | Coffee Break |
| 11:30–12:30 PM | Lunch |
| 12:30–2:30 PM | Poster Session 2 |
| 3:00–4:30 PM | Career Roundtable |
| 4:30–5:00 PM | Coffee Available |
| 5:00–7:00 PM | Mechanisms and Vulnerabilities Conferred by DNA Methylation |
| Yael David, Memorial Sloan Kettering Cancer Center Thinking Outside the Chromosome: Interrogating Epigenetic Mechanisms in Noncanonical Chromatin Species |
| Chao Lu, Columbia University At the Crossroads of Histone Modifications and DNA Methylation in Cancer |
| Alla Sigova, CAMP4 Therapeutics RNA Amplifier Therapeutics Targeting Regulatory RNAs to Upregulate Disease-Associated genes |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | On Own for Dinner |
| 7:30–8:30 AM | Breakfast |
| 8:30–11:30 AM | Interplay between Chromatin Regulation and Transcription Dynamics in Human Disease |
| Emily Bernstein, Mount Sinai School of Medicine Histone Variants and Their Functions in Cancer |
| Ali Shilatifard, Northwestern University Transcriptional Elongation and its Control of Oncogenic Mechanisms |
| Danny F Reinberg, University of Miami Opportunities in Cancer |
| Short Talk(s) Chosen from Abstracts |
| 9:30–9:50 AM | Coffee Break |
| 11:30–12:30 PM | Lunch |
| 2:30–4:30 PM | Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available |
| 5:00–6:45 PM | Chromatin Regulatory Machinery in Human Health and Disease |
| Effie Apostolou, Weill Cornell Medical College Epigenetic Mechanisms of Post-Mitotic Transcriptional Activation |
| Nada Jabado, McGill University Health Centre Epigenetics of Pediatric Brain Cancers |
| Yadira M Soto-Feliciano, Massachusetts Institute of Technology Chromatin Scaffold Proteins in Development and Disease |
| Short Talk(s) Chosen from Abstracts |
| 6:45–7:00 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
| 7:00–8:00 PM | On Own for Dinner |
| 12:00–11:59 PM | Departure |