Myeloid Cells: Roles in Different Tissue Microenvironments (C2)
March 3-6, 2025  | Herrenhausen Palace, Hannover, Germany
Irina A. Udalova, Ana-Maria Lennon-Duménil and Paul Kubes
Scholarship Deadline: Dec. 6, 2024 | Abstract Deadline: Feb. 11, 2025 | Early Registration Deadline: Jan. 15, 2025
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 4 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, March 3, 2025
4:00–8:00 PM Registration Grand Mussmann Hotel, Tivoli Room
6:00–8:00 PM Welcome Mixer Central-Hotel Kaiserhof
Tuesday, March 4, 2025
8:00–9:00 AM Breakfast Individual Hotel
8:30–9:00 AM Poster Setup Foyer
8:45–7:00 PM Poster Viewing Foyer
9:00–10:00 AM Welcome and Keynote Address Auditorium
  * Paul Kubes, University of Calgary
Session Chair
 
  * Irina A. Udalova, University of Oxford
Session Chair
 
  * Ana-Maria Lennon-Duménil, Curie Institute
Session Chair
 
  Mikael J Pittet, University of Geneva
Microenvironmental Coordination in the Control of Human Cancers
 
10:00–12:15 PM Myeloid Cells Through Life and Aging Auditorium
  * Marc Bajénoff, Centre d'Immunologie Marseille-Luminy
Session Chair
 
  * Tim Lämmermann, Max Planck Institute of Immunobiology and Epigenetics
Session Chair
 
  Sonia Garel, College de France
Decoding Microglia through the Lens of Early Development
 
  Katrin Andreasson, Stanford University
Myeloid Cells and Cognitive Decline in Aging
 
  Filip K. Swirski, Icahn School of Medicine at Mount Sinai
Impact of Lifestyle and Environment on Myeloid Cells
 
  Ciara Campbell, Imperial College London
Short Talk: Neutrophils Bound To Mast Cell Granules Induce Remote Damage During Early Life Allergen-Induced Lung Inflammation
 
10:30–10:50 AM Coffee Break Foyer
12:15–1:15 PM Lunch Ballroom
12:45–2:45 PM Poster Session 1 Foyer
2:45–4:30 PM Symposia Spotlight 1: Late Breaking Research Auditorium
  * Sonia Garel, College de France
Session Chair
 
  * Bryan Yipp, University of Calgary
Session Chair
 
  David Bejarano, LIMES Institute, University of Bonn
Spatial and Phenotypic Heterogeneity of Intestinal Macrophages
 
  Elisa Eme-Scolan, Aix-Marseille University
The Role of Myeloid Cells in Skull-To-Brain Axis & Neuroinflammation
 
  Milas Ugur, University of Wurzburg
Pulse-Chase Tracking of Myeloid Precursors Reveals the Differentiation and Maintenance of Dendritic Cells and Monocytes
 
  Beatrice Zitti, University of Geneva
Immune Regulation of CCR7+ Dendritic Cells at Tumor Sites
 
  Stijn Verwaerde, Vlaams Instituut voor Biotechnologie, Ghent University
Type-2 innate Lymphocytes Reprogram Resident Alveolar Macrophages into Drivers of Inflammation by Switching from PPAR-γ to IRF4 Regulons
 
  Lilian Salm, University of Bern
Plasma Fibronectin Released by Peritoneal Macrophages Promote Remote Skin Wound Healing
 
  Wen Peng, GIGA research, University of Liege
Endothelial Tgfβ Signaling Supports Lung Interstitial Macrophage Differentiation And Prevents Age-Related Abnormalities
 
4:30–5:00 PM Coffee Available Foyer
5:00–7:00 PM Myeloid Cells Beyond Macrophages: Granulocytes Auditorium
  * Filip K. Swirski, Icahn School of Medicine at Mount Sinai
Session Chair
 
  * Katrin Andreasson, Stanford University
Session Chair
 
  Tim Lämmermann, Max Planck Institute of Immunobiology and Epigenetics
Neutrophil Trapping by Mast Cells
 
  Paul Kubes, University of Calgary
Myeloid Cells in Tissue Repair
 
  Svetoslav Chakarov, Shanghai Jiao Tong University School of Medicine (SJTU)
Short Talk: Tissue Specific Microenvironment Drives Eosinophil Metabolic Adaptation
 
  Quin Waterbury, Columbia University Irving Medical Center
Short Talk: Neutrophil Density Controls Bone Marrow Myelopoiesis During Obesity.
 
  Julia Kolter, University of Freiburg
Short Talk: Sensory Neurons Imprint Tissue Macrophage Identity via TGF-β
 
  Daniel Crepaz, University of Zurich
Short Talk: Eosinophils Control Intestinal Commensalism to Sustain Homeostasis
 
7:00–8:00 PM Social Hour with Lite Bites Ballroom
Wednesday, March 5, 2025
8:00–9:00 AM Breakfast Individual Hotel
8:30–9:00 AM Poster Setup Foyer
8:45–7:00 PM Poster Viewing Foyer
9:00–12:00 PM Mechano-Sensing and Responses in Myeloid Cells in Tissues Auditorium
  * Menna R Clatworthy, University of Cambridge
Session Chair
 
  * Lai Guan Ng, Shanghai Immune Therapy Institute
Session Chair
 
  Mathieu Deygas, INEM/Institut Curie
Fast Adaptation to Confinement Steers Neutrophil Migration in Complex Microenvironments
 
  Spencer Freeman, SickKids Research Institute
Fluid Surveillance and Mechanotransduction in Macrophage
 
  Wendy Liu, University of California Irvine
Macrophage Responses to Mechanical Cues
 
  Marc Bajénoff, Centre d'Immunologie Marseille-Luminy
Stromal Cells as Macrophage Niches
 
  Ting Zhou, Westlake University
Short Talk: Rescuing Dendritic Cell Interstitial Motility Sustains Anti-Tumor Immunity Cycle
 
  Thomas Fabre, Pfizer
Short Talk: Expression of GPNMB in SPP1+ Scar-Associated Macrophage Promotes Fibrosis Across Organs
 
10:00–10:20 AM Coffee Break Foyer
10:20–10:25 AM Award Recipient Acknowledgement Auditorium
12:00–1:00 PM Lunch Ballroom
12:30–2:30 PM Poster Session 2 Foyer
3:00–4:30 PM Career Roundtable Auditorium
  Wendy Liu, University of California Irvine
Assistant Professor
 
  Amy Sawtell, Abbvie
Senior Scientist II
 
  Hermann Haller, Mt. Desert Island Biological Laboratory
President & Professor
 
4:30–5:00 PM Coffee Available Foyer
5:00–7:00 PM Myeloid Cells in Human Tissue and Clinical Setting Auditorium
  * Mikael J Pittet, University of Geneva
Session Chair
 
  * Christine Carine Moussion, Genentech, Inc.
Session Chair
 
  Menna R Clatworthy, University of Cambridge
Regional Environmental Cues Shaping Function of Human Kidney Macrophages
 
  Florent Ginhoux, Gustave Roussy
Heterogeneity of Tissue Resident Macrophages
 
  Fernando D Camargo, Boston Children's Hospital
Ancestry and Function in the Hematopoietic System
 
  Artur Kibler, University Hospital Essen
Short Talk: Myeloid Cells Drive Early-Life Maturation Of The Human Splenic Marginal Zone
 
  Zheng Wang, KU Leuven
Short Talk: Unveiling the Relationship Between Nerve-Associated Macrophages and nerves across different organs
 
7:00–8:00 PM Social Hour with Lite Bites Ballroom
Thursday, March 6, 2025
8:00–9:00 AM Breakfast Individual Hotel
9:00–12:00 PM Myeloid Cell Interaction with Stromal Cells in Health and Disease Tissue Auditorium
  * Wendy Liu, University of California Irvine
Session Chair
 
  Christine Carine Moussion, Genentech, Inc.
Myeloid Cells in the Tumor Microenvironment
 
  Irina A. Udalova, University of Oxford
Myeloid Cells in the Synovium - Osmotic and Mechanical Pressure
 
  Bryan Yipp, University of Calgary
Neutrophils in Human Pulmonary Host Defense
 
  Lai Guan Ng, Shanghai Immune Therapy Institute
Neutrophil Heterogeneity and Function in Tumor Setting
 
  Apple C Vollmers, Genentech
Short Talk: Dermatopontin-Expressing Fibroblasts Mediate An Essential Skin Macrophage Niche
 
  Alexander Moshensky, University of California, Irvine
Short Talk: Disentangling the Epidermal-Immune Crosstalk in Inflammatory Skin Disease
 
10:00–10:20 AM Coffee Break Foyer
12:00–1:00 PM Meet the Editors Auditorium
  Iliyan D Iliev, Weill-Cornell Medical College
*Session Chair
 
  Nick J Bernard, Nature Immunology
Senior Editor
 
  Achim Breiling, EMBO
Senior Scientific Editor
 
  Viorica Liebe Lastun, Elsevier B.V
Scientific Editor
 
  Lucie Laurien, Elsevier
Scientific Editor
 
  Lorenzo Spagnuolo, Cell Press
Scientific Editor
 
1:00–2:00 PM Lunch Ballroom
2:00–4:00 PM Symposia Spotlight 2: Short Talks and Panel - Immune Mechano-Sensing in Tissues Auditorium
  * Ana-Maria Lennon-Duménil, Curie Institute
Panelist & Session Chair
 
  Spencer Freeman, SickKids Research Institute
Panelist
 
  Wendy Liu, University of California Irvine
Panelist
 
  Irina A. Udalova, University of Oxford
Panelist
 
  Seily Shrestha, Queen's University
Fibroblast-Derived CSF1 Regulates Macrophage Dynamics In Skeletal Muscle Repair
 
  Benedicte Chazaud, Université Claude Bernard Lyon
Efferocytosis Controls Dec1/bhlhe40 for the Resolution Of Inflammation
 
  Hanrui Zhang, Columbia University
Finding and Pushing the Limits of Macrophage Efferocytosis via Genome-wide CRISPR Screening
 
  Satoshi Watanabe, Kanazawa University
Dynamics And Roles Of Macrophages In Lung Regeneration: Insights From The Mouse Pneumonectomy Model
 
  Barbora Schonfeldova, The Kennedy Institute of Rheumatology, University of Oxford
AQP1 Integrates Mechano-Osmotic Signals In Synovial Macrophages Residing In Mechanically Strained Areas Of The Joint
 
  Aline Yatim, Institut Curie Paris
Impact of Cell Confinement on Monocytes
 
4:00–4:30 PM Coffee Available Foyer
4:30–6:15 PM Myeloid Cell Interaction with Pathogens and Microbiota Auditorium
  * Spencer Freeman, SickKids Research Institute
Session Chair
 
  * Fernando D Camargo, Boston Children's Hospital
Session Chair
 
  Barbara Rehermann, NIDDK, National Institutes of Health
Remote Presenter - Wild Mouse Microbiota: Impact on Regulation of Systemic Immune Responses
 
  Ana-Maria Lennon-Duménil, Curie Institute
Myeloid Cells as Gut Sentinels - Mechanical Stress and Infection
 
  Iliyan D Iliev, Weill-Cornell Medical College
Immune Regulation by Fungal Strain Diversity in Inflammatory Bowel Disease
 
  Raymond Shim, University of Calgary
Short Talk: Kupffer Cell Antibacterial Function Requires Continual Sympathetic Nerve Output
 
6:15–6:30 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Auditorium
6:30–7:30 PM Social Hour with Lite Bites Ballroom
Friday, March 7, 2025
12:00–11:59 PM Departure