Transposable Elements: From Evolution to Engineering (C2)
March 15-18, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Irina Arkhipova, Samuel H Sternberg, Ting Wang and Phillip D. Zamore
Scholarship Deadline: Nov. 18, 2026 | Abstract Deadline: Feb. 23, 2027 | Early Registration Deadline: Jan. 14, 2027
| 4:00–8:00 PM |
Registration |
Colorado Ballroom Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
Colorado Ballroom Foyer |
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–8:10 AM |
Welcome Remarks |
Colorado Ballroom Peak 4-5 |
| 8:10–9:00 AM |
Keynote Address |
Colorado Ballroom Peak 4-5 |
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Vera Gorbunova, University of Rochester
Role of L1 Retrotransposons in Aging |
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| 9:00–11:15 AM |
Structural and Mechanistic Aspects of Transposition |
Colorado Ballroom Peak 4-5 |
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Samuel H Sternberg, Columbia University, HHMI
Functional Roles of Domesticated Reverse Transcriptases in Antiviral Immunity |
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George E. Ghanim, Princeton University
Structure and Biochemistry of L1 and Alu Retrotransposition |
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Elizabeth Kellogg, St. Jude Children's Research Hospital
Structures of the Holo CRISPR RNA-Guided Transposon Integration Complex |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
Colorado Ballroom Foyer |
| 11:25–12:25 PM |
Meet the Editors |
Colorado Ballroom Peak 4-5 |
| 12:25–1:00 PM |
Poster Setup |
Colorado Ballroom Peak 1-3 |
| 12:25–2:30 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Colorado Ballroom Peak 1-3 |
| 2:30–4:30 PM |
Symposia Spotlight 1 |
Colorado Ballroom Peak 4-5 |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
Colorado Ballroom Foyer |
| 5:00–7:00 PM |
Transposons in Genome Editing and Engineering |
Colorado Ballroom Peak 4-5 |
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R. K Slotkin, Donald Danforth Plant Science Center
The Control of Transposable Elements in Plants |
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Jonathan S. Gootenberg, Harvard Medical School
Reprogramming Site-Specific Retrotransposon Activity to New DNA Sites |
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Akanksha Thawani, Columbia University
Structures of R2 Retrotransposons during Target-Primed Reverse Transcription |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
Colorado Ballroom Peak 1-3 |
| 7:30–10:00 PM |
Poster Session 1 |
Colorado Ballroom Peak 1-3 |
Wednesday, March 17, 2027
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–11:00 AM |
Transposons in Disease and Therapeutics |
Colorado Ballroom Peak 4-5 |
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Ting Wang, Washington University
Transposable Elements and Cancer Epigenome |
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Cecilia Cotta-Ramusino, Tessera Therapeutics
Talk Title to be Announced |
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Hui Shen, Van Andel Institute
Probing Transposable Element Expression in Single Cells |
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Katherine Chiappinelli, George Washington University
The Viral Mimicry Response to Transposable Elements in Cancer |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Colorado Ballroom Foyer |
| 9:20–9:25 AM |
Award Recipient Acknowledgement |
Colorado Ballroom Peak 4-5 |
| 11:00–1:00 PM |
Poster Setup |
Colorado Ballroom Peak 1-3 |
| 11:00–3:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Colorado Ballroom Peak 1-3 |
| 3:00–4:30 PM |
Career Roundtable |
Colorado Ballroom Peak 4-5 |
| 4:30–5:00 PM |
Coffee Available |
Colorado Ballroom Foyer |
| 5:00–7:00 PM |
Evolution and Genomics |
Colorado Ballroom Peak 4-5 |
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Irina Arkhipova, Marine Biological Laboratory
Evolution of Reverse Transcription Mechanisms |
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George Kassiotis, The Francis Crick Institute
HERVs and Evolution of Host Immunity |
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Oleg Simakov, University of Vienna
The Role of Transposable Elements in Shaping Deeply Conserved Synteny in Animal Genomes |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
Colorado Ballroom Peak 1-3 |
| 7:30–10:00 PM |
Poster Session 2 |
Colorado Ballroom Peak 1-3 |
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–11:00 AM |
Small RNAs and Transposon Silencing |
Colorado Ballroom Peak 4-5 |
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Phillip D. Zamore, University of Massachusetts Chan Medical School
How are Pachytene piRNAs Made and What Do They Do? |
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Yukiko M. Yamashita, Whitehead Institute
Silencing of Transposons in rDNA and of Selfish Genetic Elements in the Male Germ Line in Flies |
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René F. Ketting, Institute for Molecular Biology
Transposon Control by Small RNAs in Nematodes |
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Ansgar Zoch, University of Edinburgh
RNA-Directed Epigenetic Silencing of Transposons in the Mammalian Male Germline |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Colorado Ballroom Foyer |
| 11:00–2:30 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2 |
Colorado Ballroom Peak 4-5 |
| |
Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
Colorado Ballroom Foyer |
| 5:00–7:00 PM |
Transposon-Host Interactions |
Colorado Ballroom Peak 4-5 |
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Sandra Duharcourt, Institut Jacques Monod
Programmed DNA Elimination in the Unicellular Eukaryote Paramecium: An Extreme Strategy for Transposon Control |
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Alexei A. Aravin, Cornell University
Evolutionary Innovations in the piRNA-based Host Defense Against TEs |
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Pierre Baduel, Ecole Normale Superieure / CNRS
Epigenomic Surveillance between TEs and Transgenerational Epigenetic Inheritance |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Colorado Ballroom Peak 4-5 |
| 7:00–8:00 PM |
Social Hour with Dinner |
Colorado Ballroom Peak 1-3 |
| 8:00–9:00 PM |
Entertainment |
Colorado Ballroom Peak 1-3 |
| 8:00–9:00 PM |
Cash Bar |
Colorado Ballroom Peak 1-3 |
