Transposable Elements: From Evolution to Engineering (C2)
March 15-18, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Irina Arkhipova, Samuel H Sternberg, Ting Wang and Phillip D. Zamore
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–9:00 AM |
Welcome and Keynote Address |
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Vera Gorbunova †, University of Rochester
Role of L1 Retrotransposons in Aging |
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| 9:00–11:15 AM |
Structural and Mechanistic Aspects of Transposition |
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Samuel H Sternberg, Columbia University
Functional Roles of Domesticated Reverse Transcriptases in Antiviral Immunity |
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George E. Ghanim †, Princeton University
Structure and Biochemistry of L1 and Alu Retrotransposition |
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Elizabeth Kellogg †, St. Jude Children's Research Hospital
Structures of the Holo CRISPR RNA-Guided Transposon Integration Complex |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–12:15 PM |
Meet the Editors |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Transposons in Genome Editing and Engineering |
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R. K Slotkin †, Donald Danforth Plant Science Center
The Future of Genome Editing in Plants |
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Jonathan S. Gootenberg †, Harvard Medical School
Reprogramming Site-Specific Retrotransposon Activity to New DNA Sites |
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Akanksha Thawani †, Columbia University
Structures of Vertebrate R2 Retrotransposon Complexes during Target-Primed Reverse Transcription |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, March 17, 2027
| 8:00–11:00 AM |
Transposons in Disease and Therapeutics |
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Ting Wang, Washington University
Transposable Elements and Cancer Epigenome |
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Heike Keilhack †, ROME Therapeutics
Drug Discovery in the Dark Genome |
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Hui Shen †, Van Andel Institute
Probing Transposable Element Expression in Single Cells |
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Katherine Chiappinelli †, George Washington University
The Viral Mimicry Response to Transposable Elements in Cancer |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Evolution and Genomics |
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Irina Arkhipova, Marine Biological Laboratory
Evolution of Reverse Transcription Mechanisms |
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George Kassiotis †, The Francis Crick Institute
HERVs and Evolution of Antiviral Host Defenses |
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Oleg Simakov †, University of Vienna
Transposable Elements and Evolution of Metazoan Genome Architecture |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Small RNAs and Transposon Silencing |
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Phillip D. Zamore, University of Massachusetts Chan Medical School
How are Pachytene piRNAs Made and What Do They Do? |
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Yukiko M. Yamashita †, Whitehead Institute
Silencing of Transposons in rDNA and of Selfish Genetic Elements in the Male Germ Line in Flies |
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René F. Ketting †, Institute for Molecular Biology
Transposon Control by Small RNAs in Nematodes |
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Ansgar Zoch †, University of Edinburgh
Transposon Silencing in the Mammalian Testis Germline |
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Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Transposon-Host Interactions |
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Deborah Bourc'his †, Institut Curie
Epigenetic Decisions and Reproduction in Mammals |
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Julius Brennecke †, IMBA - Institut für Molekulare Biotechnologie GmbH
Transposons, piRNAs and Drosophila Oogenesis |
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Vincent Colot †, École Normale Supérieure
Genetic and Epigenetic Variation and Environmental Adaptation in Arabidopsis |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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