Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations (C3)
March 15-18, 2026
| Fairmont Le Château Frontenac, Québec, QC, Canada
Jennifer Guerriero, Thomas Marron, Ira Mellman and Solange Peters
Scholarship Deadline: Nov. 12, 2025 | Abstract Deadline: Feb. 20, 2026 | Early Registration Deadline: Jan. 14, 2026
| 4:00–8:00 PM |
Registration |
Vercheres |
| 6:00–8:00 PM |
Welcome Mixer |
Vercheres |
| 7:30–8:30 AM |
Breakfast |
Frontenac / Petit Frontenac |
| 8:00–8:30 AM |
Poster Setup |
Grand Ballroom |
| 8:15–5:00 PM |
Poster Viewing |
Grand Ballroom |
| 8:30–9:30 AM |
Welcome and Keynote Address |
Grand Ballroom |
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Elizabeth M. Jaffee, Johns Hopkins University
Cancer Immunotherapy - Where do we Stand Now? |
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| 9:30–11:45 AM |
The Failures, Successes and Future of Cancer Immunotherapy |
Grand Ballroom |
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Solange Peters, CHUV
Postmortem of Failed Immunotherapy Approaches |
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James P. Allison, University of Texas MD Anderson Cancer Center
Immune Checkpoint Blockade in Cancer Immunotherapy: Mechanistic Insights Provide New Therapeutic Opportunities |
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Ira Mellman, Parker Institute for Cancer Immunotherapy
The Future of Cancer Immunotherapy |
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Short Talk(s) Chosen from Abstracts
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| 10:00–10:20 AM |
Coffee Break |
Vercheres |
| 11:45–12:45 PM |
Lunch |
Frontenac / Petit Frontenac |
| 12:30–2:30 PM |
Poster Session 1 |
Grand Ballroom |
| 2:30–4:30 PM |
Panel Discussion 1: Accelerating Development and Overcoming Regulatory Challenges of Drug Approvals |
Grand Ballroom |
| 4:30–5:00 PM |
Coffee Available |
Vercheres |
| 5:00–7:00 PM |
Probing Omics and Big Data to Identify Novel Therapeutic Targets and Biomarkers |
Grand Ballroom |
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Arielle Elkrief, Université de Montréal
The Gut Microbiome as a Therapeutic Target in Immuno-oncology |
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Padmanee Sharma, University of Texas MD Anderson Cancer Center
From the Clinic to the Lab: Investigating Mechanisms of Response and Resistance to Immune Checkpoint Therapy |
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Özlem Türeci, BioNTech
Vaccines |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
On Own for Dinner |
|
| 7:30–8:30 AM |
Breakfast |
Frontenac / Petit Frontenac |
| 8:00–8:30 AM |
Poster Setup |
Grand Ballroom |
| 8:15–5:00 PM |
Poster Viewing |
Grand Ballroom |
| 8:30–11:30 AM |
Advances and Challenges of Combination Immunotherapy of Cancer |
Grand Ballroom |
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Sandra Demaria, Weill Cornell Medical College
Challenges and Opportunities to Improve Responses to Radiation and Immunotherapy Combinations |
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Thomas Powles, Barts Cancer Institute
How to Optimally Combine Chemotherapies and Targeted Therapies with Immunotherapy |
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Thomas Marron, Icahn School of Medicine at Mount Sinai
Neoadjuvant Combination Immunotherapy Approaches: Improving Outcomes and Propelling the Science |
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Alexandra Snyder, Generate Biomedicines, Inc.
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
Vercheres |
| 9:50–9:55 AM |
Award Recipient Acknowledgement |
Grand Ballroom |
| 11:30–12:30 PM |
Lunch |
Frontenac / Petit Frontenac |
| 12:30–2:30 PM |
Poster Session 2 |
Grand Ballroom |
| 1:30–2:30 PM |
Career Roundtable |
Grand Ballroom |
| 2:45–4:30 PM |
Panel Discussion 2: “Lessons Learned” from Combination Therapy: What can be Learned from the Failures to Improve Future Successes in Combination Treatment |
Grand Ballroom |
| 4:30–5:00 PM |
Coffee Available |
Vercheres |
| 5:00–7:00 PM |
Novel Approaches for Targeting Myeloid and Stromal Cells in the Tumor Microenvironment |
Grand Ballroom |
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Shannon J Turley, Amgen Inc.
Talk Title to be Announced |
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Karin E. de Visser, Netherlands Cancer Institute
Crosstalk between Eosinophils and Adaptive Immune Cells: A New Avenue for Immune Checkpoint Blockade |
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Jennifer Guerriero, Brigham and Women's Hospital
Harnessing Macrophages for Anti-Cancer Therapy |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
On Own for Dinner |
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Wednesday, March 18, 2026
| 7:30–8:30 AM |
Breakfast |
Frontenac / Petit Frontenac |
| 8:30–11:30 AM |
Novel Insights into Tumor Recognition by Lymphocytes |
Grand Ballroom |
| |
Tullia C. Bruno, University of Pittsburgh
Harnessing B Cells Inside and Outside of Tertiary Lymphoid Structures for Improved Anti-tumor Immunity |
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Miriam Merad, Mount Sinai School of Medicine
Novel Insights into the Organization of TLS |
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E. John Wherry, University of Pennsylvania
Novel T Cell Checkpoints |
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Carl H June, University of Pennsylvania
Cellular Therapies |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
Vercheres |
| 11:30–12:30 PM |
Lunch |
Frontenac / Petit Frontenac |
| 12:45–2:00 PM |
Panel: Perspectives: Personalized Medicine & Patient-Centered Strategies |
Grand Ballroom |
| 2:30–4:30 PM |
Workshop: Novel Platforms to Understand Mechanisms of Action and Resistance |
Grand Ballroom |
| 4:30–5:00 PM |
Coffee Available |
Vercheres |
| 5:00–6:45 PM |
Cancer Immunotherapy: Overcoming Resistance |
Grand Ballroom |
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Hélène Salmon, Institut Curie
Factors of TME Resistance |
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Charles Swanton, Francis Crick Institute
Clonal Evolution and Immune Evasion |
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Andy Minn †, Memorial Sloan Kettering Cancer Center
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Grand Ballroom |
| 7:00–8:00 PM |
On Own for Dinner |
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