Cardiovascular Epigenetics and Gene Regulation (C5)
April 15-18, 2024
| Herrenhausen Palace, Hannover, Germany
Roger Foo, Federica Accornero and Enzo R. Porrello
Scholarship Deadline: Jan. 23, 2024 | Abstract Deadline: Jan. 23, 2024 | Early Registration Deadline: Feb. 14, 2024
| 4:00–8:00 PM |
Arrival and Registration |
Grand Mussmann Hotel, Tivoli Room |
| 6:00–8:00 PM |
Welcome Mixer |
Central-Hotel Kaiserhof |
| 8:00–9:00 AM |
Breakfast |
Individual Hotel |
| 8:30–9:00 AM |
Poster Setup |
Ballroom |
| 9:00–10:00 AM |
Welcome and Keynote Address |
Auditorium |
| |
Wolf Reik, Altos Labs, Cambridge Institute of Science
Epigenetic Reprogramming in Development and Ageing |
|
| 9:00–7:00 PM |
Poster Viewing |
Ballroom |
| 10:00–12:15 PM |
Epigenome, 3D Chromatin Conformation and New Technology |
Auditorium |
| |
Leslie A. Leinwand, University of Colorado Boulder
Plasticity in the Heart in Health and Disease |
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| |
Yibin Wang, Duke-NUS, Singapore
Ribosome Biogenesis Control in Cardiac Hypertrophy |
|
| |
Emily S. Wong, Victor Chang Cardiac Research Institute
Evolutionary Enhancer Code and 3D Chromatin |
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| |
Lorenz H Lehmann, University of Heidelberg
Short Talk: Short Talk: A Memorized Superenhancer Regulates Metabolic Flexibility via Retinoid Acid Signaling in the Heart |
|
| 10:30–10:50 AM |
Coffee Break |
Foyer |
| 12:15–1:15 PM |
Lunch |
Ballroom |
| 1:00–3:00 PM |
Poster Session |
Ballroom |
| 3:30–4:30 PM |
Career Roundtable |
Ballroom |
| |
Yibin Wang, Duke-NUS, Singapore
Professor & Director |
|
| |
Gergana Dobreva, Heidelberg University
Professor & Medical Faculty |
|
| |
Xuhui Feng, Bristol Myers Squibb
Senior Scientist |
|
| 4:30–5:00 PM |
Coffee Available |
Foyer |
| 5:00–7:00 PM |
Gene Regulation, Cell States and Regeneration |
Auditorium |
| |
Enzo R. Porrello, Murdoch Children's Research Institute
Enhancing Maturation of Stem Cell-derived Cardiomyocytes |
|
| |
Li Qian, University of North Carolina at Chapel Hill
Epigenetic Regulation of Cardiac Reprogramming |
|
| |
Lynn Devilee, QIMR Berghofer
Short Talk: Short Talk: Cell Cycle Re-Entry Follows Functional Inhibition of Cardiomyocytes in Mature Human Cardiac Organoids |
|
| |
Ahmed I. Mahmoud, University of Wisconsin - Madison
Short Talk: Short Talk: Decoding the Interplay Between Metabolism and Epigenetics During Adult Heart Regeneration |
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| |
Nathan Palpant, University of Queensland
Short Talk: HOPX Associated Molecular Programs Control Cardiomyocyte Cell States Underpinning Cardiac Development and Disease |
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| |
Shambhabi Chatterjee, Hannover Medical School
Short Talk: Short Talk: Telomerase is Crucial for Survival, Function and Regeneration of Cardiomyocytes |
|
| 7:00–8:00 PM |
Social Hour with Lite Bites |
Ballroom |
Wednesday, April 17, 2024
| 8:00–9:00 AM |
Breakfast |
Individual Hotel |
| 9:00–12:00 PM |
Metabolism, Obesity and Gene Regulation |
Auditorium |
| |
Thomas Thum, Medical School Hannover
Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Diseases |
|
| |
Johannes Backs, University of Heidelberg
HDAC Signaling in Cardiometabolic Disease |
|
| |
Kathy Lui, Chinese University of Hong Kong
YY1 Epigenetically Orchestrates Vascular Contraction by Controlling transcript Stability in VSMCs |
|
| |
Pieterjan Dierickx, Max Planck for Heart & Lung Research
Short Talk: Short Talk: NAD+ Controls Circadian Rhythmic Gene Expression During Cardiac Aging |
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| |
Niranjana Natarajan, Universitty of Pittsburgh
Short Talk: Short Talk: Epigenetic Regulation of Macrophage Function in Cardiovascular Disease |
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| |
Emmanouil Georgios Solomonidis, Goethe University
Short Talk: Short Talk: Hematopoietic Loss of KDM6A Impairs Cardiac Recovery Post Myocardial Infarction via Pro-Inflammatory Myeloid Cells |
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| |
Junedh Mahesh Amrute, Washington University School of Medicine in St. Louis
Short Talk: Short Talk: Runx1 Gene Regulatory Network in Macrophages Facilitates Cardiac Recovery |
|
| 10:00–10:20 AM |
Coffee Break |
Foyer |
| 12:00–1:00 PM |
Lunch |
Ballroom |
| 1:00–2:30 PM |
Independent Exploration of the Gardens |
Herrenhausen Palace |
| 2:30–4:30 PM |
Workshop |
Auditorium |
| |
Alessia Costa, MHH
An Engineered Reporter Tool to Track Human Cardiomyocyte Proliferation |
|
| |
Diana Harleidy Vargas-Trujillo, ALPINA
Effect of Nutritional Modulation in Microbial-Derived Succinate Pathways and its Epigenetic Implications in Cardiovascular Disease |
|
| |
Cheng-Fu Kao, Academia Sinica
Epigenetic Regulator RNF20 Underlies Temporal Hierarchy of Gene Expression to Regulate Postnatal Cardiomyocyte Polarization |
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| |
Christian Bär, Institute of Molecular and Translational Therapeutic Strategies - IMTTS
Long Non-Coding RNA Foxo6os Prevents Cardiomyocyte Death and Attenuates Myocardial Infarction Injury |
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| |
Alexandre R. Colas, Sanford-Burnham Medical Research Institute
Transcription Factor-Mediated Control of Chromatin Accessibility During Cardiac Reprogramming |
|
| 4:30–5:00 PM |
Coffee Available |
Foyer |
| 5:00–7:00 PM |
Histones and DNA Regulatory Elements |
Auditorium |
| |
James E. Hudson, QIMR Berghofer Medical Research Institute
BET Inhibitors for CVD |
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| |
Timothy A. McKinsey, University of Colorado Denver
Unexpected Roles for HDAC11 |
|
| |
Roger Foo, National University of Singapore
Multiplex Assessment of Cardiac Distal Regulatory Elements |
|
| |
Artemy Zhigulev, KTH Royal Institute of Technology
Short Talk: Short Talk: The Role of Rare Enhancer Variants in Bicuspid Aortic Valve Pathology |
|
| |
Chang Jie Mick Lee, National University of Singapore
Short Talk: Short Talk: Validating Functional Histone-acetylated Variant Enhancers in Human Hearts using a STARR-seq Approach |
|
| 7:00–8:00 PM |
Social Hour with Lite Bites |
Ballroom |
| 8:00–9:00 AM |
Breakfast |
Individual Hotel |
| 9:00–12:00 PM |
Vascular Gene Regulation |
Auditorium |
| |
Saptarsi M. Haldar, Amgen Inc.
Drug Discovery in CVD Epigenetics |
|
| |
Costanza Emanueli, Imperial College London
Regulation of MicroRNA Expression and Function in the Human Heart |
|
| |
Hanjoong Jo, Emory University
Flow-induced Vascular Cell Reprogramming and Atherosclerosis by Transcriptomic and Epigenomic Regulation |
|
| |
Gergana Dobreva, Heidelberg University
Epigenetic Regulation of Cardiovascular Cell Fate and Function |
|
| |
Janice Reid, QIMR Berghofer Medical Research Institute
Short Talk: Short Talk: Constructing a Ligand Signaling Transcriptome Encyclopedia for the Heart |
|
| 10:00–10:20 AM |
Coffee Break |
Foyer |
| 12:00–1:00 PM |
Lunch |
Ballroom |
| 1:00–2:45 PM |
Epitranscriptomics, RNA and DNA Modifications |
Auditorium |
| |
Federica Accornero, Brown University
RNA-Dependent Mechanisms of Heart Failure |
|
| |
Ralf Gilsbach, Institute of Experimental Cardiology Heidelberg University Hospital
Decoding and Functional Modulation of Cardiac Regulatory Elements |
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| |
Izhak Kehat, Technion –Israel Institute of Technology
Localised Translation in Cardiomyocytes |
|
| |
Changcheng Zhou, University of California, Riverside
Short Talk: Short Talk: Paternal Hypercholesterolemia Alters Sperm tsRNAs/rsRNAs and Elicits Sex-Specific Exacerbation of Atherosclerosis in Offspring |
|
| 2:45–3:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Auditorium |
| 3:00–4:00 PM |
Cocktail Hour with Snacks |
Foyer |
