4:00–8:00 PM | Arrival and Registration | INEC Foyer |
6:00–8:00 PM | Welcome Mixer | INEC Foyer |
7:00–8:00 AM | Breakfast | Individual Hotel |
8:00–9:00 AM | Welcome and Keynote Address | INEC Main Auditorium |
* Miriam Merad, Mount Sinai School of Medicine Session Chair |
* Matthew F. Krummel, University of California, San Francisco Session Chair |
Martin Guilliams, Ghent University - VIB DC and Macrophage Diversity in Health and Diseases |
9:00–11:15 AM | Developmental Regulation of Myeloid Cells in Cancer and Beyond | INEC Main Auditorium |
Miriam Merad, Mount Sinai School of Medicine Enhancing DC Function in the TME |
* Christine Carine Moussion, Genentech, Inc. Spatial Organization of Myeloid Programs in the TME |
Merav Cohen, Tel-Aviv University Myeloid Cellular Cross-Talks During Cancer Development |
Robert Samstein, Icahn School of Medicine at Mount Sinai Short Talk: Short Talk: HLA Class II Mediated Immune Surveillance of Lung Cancer |
9:30–9:50 AM | Coffee Break | INEC Foyer |
11:15–1:00 PM | Poster Setup | INEC Foyer |
11:15–5:00 PM | On Own for Lunch |
1:00–10:00 PM | Poster Viewing | INEC Foyer |
3:30–4:30 PM | Career Roundtable | INEC Main Auditorium |
Judith A. Varner, University of California, San Diego Professor, Pathology |
Venkataraman Sriram, Foundery Innovations Founder, Managing Member, & Chief Scientific Officer |
Matteo Iannacone, San Raffaele Scientific Institute & University Group Leader |
4:30–5:00 PM | Coffee Available | INEC Foyer |
5:00–7:00 PM | Enhancing DC Functionality in the TME | INEC Main Auditorium |
* Matthew F. Krummel, University of California, San Francisco Session Chair |
* Miriam Merad, Mount Sinai School of Medicine Session Chair |
Rony Dahan, Weizmann Institute of Science Antibody Targeting of Dendritic Cells in Cancer |
Ruth Lan, Asher Biotherapeutics Cell-Specific Cytokine Delivery |
Livia Lacerda Mariano, Institute Curie Short Talk: Short Talk: The TRPML1 Calcium Lysosomal Channel Controls Dendritic Cell Migration and Anti-tumor Immunity |
Raphael Mattiuz, Icahn School of Medicine at Mount Sinai Short Talk: Short Talk: Dendritic Cells Form and Maintain Tertiary Lymphoid Structures (TLSs) in Cancer Contributing to Immunotherapeutic Responses |
7:00–8:00 PM | Social Hour with Lite Bites | INEC Foyer |
7:30–10:00 PM | Poster Session 1 | INEC Foyer |
7:00–8:00 AM | Breakfast | Individual Hotel |
8:00–11:00 AM | Boosting Macrophage Tumorigenic Function | INEC Main Auditorium |
* Julie Helft, Institut Cochin FOLR2+ Macs and Antitumor Immunity |
Jennifer Guerriero, Brigham and Women's Hospital Metabolic Targeting of Tumor Macrophages |
* Philippe Benaroch, INSERM Institut Curie Myeloid Cell Engineering for Anti-Tumor Treatments |
Ido Amit, Weizmann Institute Mapping Macrophages Inflammatory Programs |
Florent Ginhoux, Singapore Immunology Network Regulation of Monocyte-Derived Cells Differentiation in Inflamed Tissues |
Meijun Wang, City University of Hong Kong (Shenzhen) Research Institute Short Talk: Short Talk: Investigate the Role of IRF5 in Macrophages and Myeloid Cells in Anti-Tumor Immunity |
Lea Feldmann, Institut Pasteur Short Talk: Short Talk: Understanding the Antitumoral Activity of CAR-Macrophages |
9:00–9:20 AM | Coffee Break | INEC Foyer |
11:00–1:00 PM | Poster Setup | INEC Foyer |
11:00–5:00 PM | On Own for Lunch |
1:00–10:00 PM | Poster Viewing | INEC Foyer |
2:30–4:30 PM | Workshop | INEC Main Auditorium |
Dalton Hermans, National Institutes of Health ACT-VAX-INNATE: An Integrated Approach for Enhancing Tumor Control with Adoptive T Cell Therapy |
* Alexander B. Sigalov, SignaBlok, Inc. Ligand-Independent TREM-1 Blockade in Cancer Treatment |
Thomas Jaquin, IOmx Therapeutics AG IOMX-0675 , a LILRB1 and LILRB2 Cross-Specific Antibody, Effectively Repolarizes Immunosuppressive Myeloid Cells and Activates T Cells Leading to Potent Tumor Cell Killing |
Martina Molgora, Washington University School of Medicine Lack of TREM2 During anti-PD1 Therapy Reprograms Intestinal Macrophages and Microbiota to Enhance Tumor Rejection |
Daniela C Cerezo-Wallis, Yale University Cancer Enables Auxiliary Pathways of Granulopoiesis to Potentiate Tumorassociated Neutrophils |
* Damya Laoui, Vrije Universiteit Brussel-VIB Intratumoral Delivery of Lipid Nanoparticle-Formulated mRNA Encoding IL-21, IL-7, and 4-1BBL Induces Anti-Tumor Immunity |
Cristina Contreras Burrola, National Cancer Institute Going the Distance: Uncovering a Global Myeloid Reprogramming in Human Metastatic and Adjacent Microenvironments |
Garett Dunsmore, University of Paris Saclay Timing and Location Dictate Monocyte Fate and Their Transition to Tumor-Associated Macrophages |
4:30–5:00 PM | Coffee Available | INEC Foyer |
5:00–7:00 PM | Dampening Myeloid Regulatory Programs | INEC Main Auditorium |
* Martin Guilliams, Ghent University - VIB Session Chair |
Venkataraman Sriram, Foundery Innovations Targeting Trem2 in Cancer Patients |
* Judith A. Varner, University of California, San Diego Targeting Immunosupressive Macrophages |
Megan Clark, UPenn Short Talk: Short Talk: Mitochondrial NDUFA4 is a Functional Switch Controlling TAM Function and Tumor Immunity |
Nicoletta Caronni, Ospedale San Raffaele Short Talk: Short Talk: IL-1β+ Macrophages Fuel Pathogenic Inflammation in Pancreatic Cancer |
Matthew Arvedson, UCSF Short Talk: Short Talk: Aire-Expressing Tumor-Associated Macrophages Promote Cancer Immune Evasion |
Samarth Hegde, Icahn School of Medicine at Mount Sinai Short Talk: Short Talk: Epigenetic Dysregulation of Myeloid Progenitors Fuel Immunosuppressive Macrophages in Tumor Microenvironment |
7:00–8:00 PM | Social Hour with Lite Bites | INEC Foyer |
7:30–10:00 PM | Poster Session 2 | INEC Foyer |
7:00–8:00 AM | Breakfast | Individual Hotel |
8:00–11:00 AM | Myeloid Cell Control of the Tissue Ecosystem | INEC Main Auditorium |
* Matthew F. Krummel, University of California, San Francisco Space-Time 'Movements' in Tissues |
* Laurence Zitvogel, Institut Gustave Roussy Bile Acids Module the Gut Immune Rheostat Tuning Cancer Immunosurveillance |
Luke A. J. O'Neill, Trinity Biomedical Sciences Institute A Break in Mitochondrial Endosymbiosis as a Basis for Inflammatory Diseases |
Jo A. Van Ginderachter, Vrije Universiteit Brussel Short Talk: Short Talk: Kupffer Cell-Derived MIF as Regulator of Liver Metastasis |
Ayumi Kuratani, Osaka University Short Talk: Short Talk: Identification of a Tumor-Specific Macrophage Subset and its Functional Analysis by Labeling and Depletion Using the Novel VeDTR Mouse System |
9:00–9:20 AM | Coffee Break | INEC Foyer |
11:00–5:00 PM | On Own for Lunch |
4:30–5:00 PM | Coffee Available | INEC Foyer |
5:00–6:45 PM | Myeloid Cells in Viral and Inflammatory Diseases | INEC Main Auditorium |
* Matteo Iannacone, San Raffaele Scientific Institute & University Targeting Myeloid Cells in Viral Diseases |
* Carla V. Rothlin, Yale University Myeloid and Stromal Crosstalk in Non-Resolving Inflammation |
Duale A Ahmed, Carleton University Short Talk: Short Talk: Vaccinia-Induced Early Anti-Tumour Immune Responses Are Dependent on Differential Reprogramming of Myeloid Cell Populations in Highly Versus Weakly Immunogenic Murine Cancer Models |
6:45–7:00 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | INEC Main Auditorium |
7:00–8:00 PM | Social Hour with Lite Bites | INEC Foyer |
8:00–9:00 PM | Cash Bar | INEC Foyer |
7:00–11:59 PM | Departure |