4:00–6:00 PM | Workshop on Networking & Communication Skills for Early-Career Scientists | Peaks 4-5 |
4:00–8:00 PM | Registration | Colorado Ballroom Foyer |
6:00–8:00 PM | Welcome Mixer | Colorado Ballroom Foyer |
7:00–8:00 AM | Breakfast | Summit Gallery |
8:00–9:00 AM | Welcome and Keynote Address | Peaks 4 - 5 |
* Valerie B. O'Donnell, Cardiff University |
* Junken Aoki, University of Tokyo |
Marcus Conrad, Helmholtz Zentrum München Role of Lipids in Driving Ferroptosis in Mitochondria |
9:00–11:15 AM | Organelle Stress and Ferroptosis in Health and Diseases | Peaks 4 - 5 |
* L. A Cowart, Virginia Commonwealth University Session Chair |
Karen Reue, University of California, Los Angeles Identification of Genes that Control Lipid Metabolism |
Guillaume Thibault, Nanyang Technological University Lipid Bilayer Stress-Induced Unfolded Protein Response in Aging |
James A Olzmann, University of California, Berkeley At The Intersection of Lipid Droplets and Ferroptosis |
Cyrus Nikain, Memorial Sloan Kettering Cancer Center, New York Short Talk: IFITM3 Regulates Ferroptosis Through Membrane Remodeling |
9:30–9:50 AM | Coffee Break | Colorado Ballroom Foyer |
11:15–1:00 PM | Poster Setup | Peaks 1 - 3 |
11:15–2:30 PM | On Own for Lunch |
1:00–10:00 PM | Poster Viewing | Peaks 1 - 3 |
2:30–4:30 PM | LIPID MAPS/ILS Workshop | Peaks 4 - 5 |
Kim Ekroos, Lipidomics Consulting Ltd. |
Gerhard Liebisch, University of Regensburg |
Matthew Conroy, Cardiff University |
Dominik Kopczynski, University of Vienna |
4:30–5:00 PM | Coffee Available | Colorado Ballroom Foyer |
5:00–7:00 PM | Lipids in Metabolic Disease | Peaks 4 - 5 |
* Valerie B. O'Donnell, Cardiff University Session Chair |
* Michael H. Gelb, University of Washington Session Chair |
Judith A. Simcox, University of Wisconsin - Madison Regulation of Energy Expenditure by Plasma Lipid Signaling |
Russell A. DeBose-Boyd, University of Texas Southwestern Medical Center Cholesterol Metabolism |
L. A Cowart, Virginia Commonwealth University Diversity of Structures and Roles of Atypical Sphingolipids |
Mehdi Damaghi, Stony Brook University Short Talk: Sphingolipids Metabolic Plasticity Defines Cancer Cell Fitness in Adaptation to Acidic Tumor Microenvironments |
Robert Ahrends, University of Vienna Short Talk: Critical Shifts In Lipid Metabolism Promote Megakaryocyte Differentiation And Proplatelet Formation |
7:00–8:00 PM | Social Hour with Lite Bites | Peaks 1 - 3 |
7:30–10:00 PM | Poster Session 1 | Peaks 1 - 3 |
7:00–8:00 AM | Breakfast | Summit Gallery |
8:00–11:00 AM | Role of Lipids in Organisms and Metabolic Disease | Peaks 4 - 5 |
* Karen Reue, University of California, Los Angeles Session Chair |
* Judith A. Simcox, University of Wisconsin - Madison Session Chair |
Dominic Campopiano, University of Edinburgh Remote Presentation: Novel Sphingolipids Generated by Bacteria |
Michael H. Gelb, University of Washington Mass Spectrometry-Based Expansion of Newborn Screening |
Edward A Dennis, University of California, San Diego Specificity of Lipid Enzymes in Cellular Function and Metabolic Disease |
Yarden Ariav, Weizmann Institute of Science Short Talk: Elevating cGMP Levels Through PDE5A Inhibition Restricts Cancer Metastasis By Impeding NPC1-Mediated Cholesterol Trafficking |
Eugene Koo, University of Texas Southwestern Medical Center Short Talk: Bacterial Lipopolysaccharide Stimulates Long Chain Fatty Acid Uptake in The Small Intestine |
Josie Daldegan Rezende, University of Maryland, Baltimore Short Talk: Correlation Of Hepatoxicity Markers And Sphingolipid Enzymatic Activity To Sphingolipid Structure And Abundance |
Xiaoman Liu, The Broad Institute of MIT and Harvard Short Talk: Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking Akap11, a Risk Gene for Schizophrenia and Bipolar Disorder |
9:00–9:20 AM | Coffee Break | Colorado Ballroom Foyer |
9:20–9:25 AM | Award Recipient Acknowledgement | Peaks 4 - 5 |
11:00–1:00 PM | Poster Setup | Peaks 1 - 3 |
11:00–3:00 PM | On Own for Lunch |
1:00–10:00 PM | Poster Viewing | Peaks 1 - 3 |
1:30–2:30 PM | Career Roundtable | Peaks 4 - 5 |
Judith A. Simcox, University of Wisconsin - Madison Assistant Professor |
Robert Ahrends, University of Vienna Professor |
Camille M Konopnicki, Korro Bio Principal Scientist |
3:00–4:30 PM | Intersections between Lipid Metabolism and Ferroptosis | Peaks 4 - 5 |
* Ginger L. Milne, Vanderbilt University Medical Center Session Chair |
* Marcus Conrad, Helmholtz Zentrum München Session Chair |
Daniela Costa, Cardiff University Platelet-Derived Enzymatically Oxidized Phospholipids Link Coagulopathies To Systemic Inflammation In Thromboembolic Disease |
Javier Garcia-Bermudez, University of Texas Southwestern Medical Center Dissecting The Roles Of Lipid Uptake In Tumors |
Justine Mucinski, AdventHealth Effects of 24 months of calorie restriction on circulating ceramides and associated sphingolipids in healthy adults |
Michele R Plewes, University of Nebraska Medical Center Dysregulated Lipid Metabolism and SREBP1/2 Signaling Contribute to Granulosa Cell Dysfunction and Impaired Ovarian Response |
Sri Ramya Donepudi, University of Pittsburgh Investigating The Role Of Epoxyeicosatrienoic Acids In Allergic Asthma: Sex Differences And The Effect Of Seh Inhibitor On Lung Function In Females And Males |
Ke Shan, Duke Univeristy TMEM16F as a Regulator of Ferroptosis in Astrocytes and Trophoblasts: Implications for Neurodegeneration and Placental Biology |
4:30–5:00 PM | Coffee Available | Colorado Ballroom Foyer |
5:00–7:00 PM | Phospholipid Metabolism in Physiology and Disease | Peaks 4 - 5 |
* Alan R Brash, Vanderbilt University School of Medicine Session Chair |
* Guillaume Thibault, Nanyang Technological University Session Chair |
Timothy T Hla, Boston Children's Hospital/Harvard Medical School Endothelial Protective Property of S1P as a Therapeutic Strategy in Diseases of Multiple Organ Systems |
Junken Aoki, University of Tokyo An Emerging Role of PAQR Family Members as Phospholipid Remodeling PLA2 |
William L. Holland, University of Utah Genetics of Hyperceramidemia |
Gerhard Liebisch, University of Regensburg Lipidomics Reveals Novel Insights into Platelet Activation in Patients with Antiphospholipid Syndrome |
7:00–8:00 PM | Social Hour with Lite Bites | Peaks 1 - 3 |
7:30–10:00 PM | Poster Session 2 | Peaks 1 - 3 |
7:00–8:00 AM | Breakfast | Summit Gallery |
8:00–11:00 AM | Lipids and Regulation of Cellular Homeostasis | Peaks 4 - 5 |
* Junken Aoki, University of Tokyo Session Chair |
Takeshi Harayama, Institute of Molecular and Cellular Pharmacology Manipulating Cellular Lipidome to Discover Novel Regulatory Mechanisms of Lipid Composition |
Meng C. Wang, HHMI/Janelia Research Campus Lysosome Lipid Signaling in Neurons Regulates Longevity |
Stacy L Gelhaus, University of Pittsburgh Electrophilic Fatty Acid Regulation of Cellular Metabolism Mediates Inflammation Resolution |
Kasparas Petkevicius, University of Cambridge CLN8 is an acyltransferase catalyzing a key step in bis(monoacylglycero)phosphate biosynthesis |
Maia Kinnebrew, Stanford University Short Talk: ACC1 Links Lipid Droplet Metabolism to Cellular Cholesterol Homeostasis |
Johannes Morstein, UCSF Short Talk: Direct Targeting of Protein-Membrane Interactions |
Gregory Wyant, MGH/HMS Short Talk: Plasmalogen Control of Peroxisome Degradation Confers Ischemic Protection |
9:00–9:20 AM | Coffee Break | Colorado Ballroom Foyer |
11:00–11:10 AM | People's Choice Poster Award Announcement | Peaks 4 - 5 |
11:10–2:30 PM | On Own for Lunch |
2:30–4:30 PM | Symposia Spotlight: Research Presentations Selected from Abstract Submissions | Peaks 4 - 5 |
* Stacy L Gelhaus, University of Pittsburgh Session Chair |
* William L. Holland, University of Utah Session Chair |
Alan R Brash, Vanderbilt University School of Medicine Structural Basis Of Covalent Binding Of Acylceramides In Formation Of The Skin Permeability Barrier |
Alessandra Ferrari, University of California, Berkeley Nonvesicular Trafficking In Enterocytes Facilitates The Uptake Of Diet-Derived Cholesterol |
Anna Hains, University of Manchester Ceramides Mediate the Resolution of Psoriasis-Like Skin Inflammation |
Takese T McKenzie, MD Anderson Cancer Center Loss Of Lipocalin Prostaglandin D2 Synthase Impairs Myelin Debris Clearance And Microglial Activation During Demyelination |
Ginger L. Milne, Vanderbilt University Medical Center Metabolism Of Oxidized Lipid Mediators By UDP-Glucuronosyltransferases (Ugts): Implications For In Vivo Quantification |
Brendan Prideaux, University of Texas Medical Branch Spatial Lipidomic Analysis of Inflammatory Pathways in Pulmonary Tuberculosis |
Bin Zheng, Cedars-Sinai Medical Center DHODH Modulates Immune Evasion of Cancer Cells Via CDP-Choline Dependent Regulation of Phospholipid Metabolism |
4:30–5:00 PM | Coffee Available | Colorado Ballroom Foyer |
5:00–6:30 PM | Bioactive Lipids in Inflammatory Disease | Peaks 4 - 5 |
* James A Olzmann, University of California, Berkeley Session Chair |
Valerie B. O'Donnell, Cardiff University The SARS-CoV2 Envelope Responds to Host Lipid Metabolism through Changing its Coat |
Scott A. Summers, University of Utah Remodeling the Ceramide Backbone to Treat Cardiorenal Metabolic Disease |
Mei Yee Koh, University of Utah Short Talk: HAF Promotes Lipid Dysregulation and Progression from MASH to MASH-HCC |
Marta Overchuk, University of North Carolina at Chapel Hill Short Talk: Concurrent Induction of Ferroptosis- and Apoptosis-like Lipid Signatures in Ovarian Cancer Cells with Photodynamic Therapy |
6:30–6:45 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | Peaks 4 - 5 |
6:45–8:00 PM | Social Hour with Lite Bites | Peaks 1 - 3 |
7:30–9:00 PM | Entertainment | Peaks 4 - 5 |
8:00–9:00 PM | Cash Bar | Peaks 1 - 3 |
12:00–11:59 PM | Departure |