Solute Carrier Transporters: Structure, Physiology and Pharmacology (D1)
April 13-16, 2026  | Wylie Center and Tupper Manor at Endicott College, Beverly, MA, United States
Giulio Superti-Furga, David Drew and Kathleen Giacomini
Scholarship Deadline: Jan. 8, 2026 | Abstract Deadline: Mar. 24, 2026 | Early Registration Deadline: Feb. 13, 2026
* Session Chair † Invited but not yet accepted | Program current as of April 6, 2026 1 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, April 13, 2026
4:00–8:00 PM Registration Conference Center Atrium
6:00–8:00 PM Welcome Mixer Conference Center Atrium
Tuesday, April 14, 2026
7:30–8:30 AM Breakfast Beverly Foyer
8:00–8:30 AM Poster Setup Ipswich
8:30–8:40 AM Welcome Remarks Beverly Room
8:30–5:00 PM Poster Viewing Ipswich
8:40–9:30 AM Drs. Edward and Martha Dennis Endowed Keynote Address Beverly Room
  Olga Boudker, Weill Cornell Medical College
Structure-Function-Mechanism of Neuronal Glutamate Transporters		  
9:30–11:30 AM Membrane Transporters and Metabolism Beverly Room
  Rajini Rao, Johns Hopkins University
Ion Transporters		  
  David Drew, Stockholm University
Two-step Mechanism for Sugar Translocation		  
  Sarah-Maria Fendt, VIB-KU Leuven
Metabolism of Cancer Cells		  
  Daniel Bondeson, UMass Chan Medical School
Short Talk: Exploiting Inorganic Phosphate Sensing and Efflux Pathways as Therapeutic Vulnerabilities in Cancer		  
10:00–10:20 AM Coffee Break Beverly Foyer
11:30–12:30 PM Lunch Newburyport
12:00–2:00 PM Poster Session 1 Ipswich
2:00–4:00 PM Symposia Spotlight 1: Transporters as Regulators of Cellular Homeostasis Beverly Room
  Melinda M Diver, Memorial Sloan Kettering Cancer Center
Gatekeepers of Phosphate Homeostasis: Unveiling the Unconventional Mechanism of SLC34 Transporters		  
  Yingze Ma, Johns Hopkins University School of Medicine
Dietary Fat Enhances Intestinal Copper Absorption by Modulating Copper Transporter 1 (CTR1/SLC31A1)		  
  Jan Spaas, Stanford University
SLC16A13 is a New Pantothenate Transporter linked to Cardiometabolic Disease		  
  Krishna Reddy, University of South Florida
Assembly and Biogenesis of an Elevator-Type SLC Transporter		  
  Alastair Stewart, The Victor Chang Cardiac Research Institute
Structural Basis of Sodium Ion-Dependent Carnitine Transport by OCTN2		  
  Peixuan Yu, Michigan State University
Structure and Post-Translational Modification of the Prostaglandin Transporter		  
  Eric M. Morrow, Brown University
Na+/H+ Exchanger 6 (NHE6) Function in Endosome Maturation and Neurodegeneration		  
4:00–4:30 PM Coffee Available Beverly Foyer
4:30–6:00 PM Transporters and the CNS Beverly Room
  Ligong Chen, Tsinghua University
An Unconventional and Neglected Iron Transporter in Brain		  
  Laura Cancedda, Istituto Italiano di Tecnologia and IAMA Therapeutics
Targeting NKCC Transport Proteins - New Treatments Against CNS Disorders		  
  Dushyant Kumar Srivastava, Vollum Institute, Oregon Health & Science University
Short Talk: Insights into the Allosteric Inhibitory Mechanisms in the Human Dopamine Transporter		  
  Yihan Zhao, Icahn school of medicine at Mount Sinai
Short Talk: Rational Design of First In-Class Small Molecule Inhibitors for a Brain Bicarbonate Transporter		  
6:00–9:30 PM Transportation to Town for Dinner Options
Wednesday, April 15, 2026
12:00–2:00 PM Poster Session 2 Ipswich
7:30–8:30 AM Breakfast Beverly Foyer
8:00–8:30 AM Poster Setup Ipswich
8:30–11:30 AM Transporter Genetics and Metabolomics Beverly Room
  Giulio Superti-Furga, Research Center for Molecular Medicine of the Austrian Academy of Sciences
Membrane Transporters as Mediators of Physiology across Cells and Ecosystems		  
  Nora Kory, Harvard T.H Chan School of Public Health
Mitochondrial Transporters and the Control of Cellular Metabolism		  
  Nancy Carrasco, Vanderbilt University
The Tale of the Sodium/iodide Symporter (NIS): From Cloning to Structure to Engineering		  
  Kim L Brouwer, University of North Carolina at Chapel Hill
Liver Disease-mediated Alterations in Hepatic SLC51A/B and SLCO2B1 Localization and Function		  
  Joseph R Visker, University of Utah & Wake Forest University
Short Talk: Solute-Carrier Bypass for Cardiac Carbohydrate Oxidation Under Stress		  
8:30–5:00 PM Poster Viewing Ipswich
9:30–9:50 AM Coffee Break Beverly Foyer
11:30–12:30 PM Lunch Newburyport
2:15–3:30 PM Career Roundtable Beverly Room
  Nicolas Reyes, National Center of Scientific Research
Research Director		  
  Erica Evans, Curie.Bio
Senior Vice President		  
3:30–4:00 PM Coffee Available Beverly Foyer
4:00–6:00 PM Integrative Transporter Complexes and Organelles Beverly Room
  Simon Newstead, University of Oxford
Understanding the Role of SLCs in Chronic Pain in the Human Body		  
  Nicolas Reyes, National Center of Scientific Research
Recognition of Solute Carriers by Retrovirus-Derived Human Proteins		  
  Kivanc Birsoy, Rockefeller University
Mitochondrial Carrier Physiology		  
  Xujun Cao, Arc Institute
Short Talk: Conserved Lysosomal Transporters Regulate cGAMP–STING Signaling by Direct cGAMP Sequestration		  
6:00–9:00 PM Transportation to Town for Dinner Options
Thursday, April 16, 2026
7:30–8:30 AM Breakfast Beverly Foyer
8:30–11:30 AM Emerging SLC Technologies for Drug Discovery Beverly Room
  Zhen Chen,  X-Chem
Application of DNA Encoded Libraries to Solute Carrier Drug Discovery		  
  Shane Hegarty, Axonis
Development of First-In-Class KCC2 Potentiators for the Treatment of CNS Disorders		  
  Erik Lindström, Ipsen
Bile Acid Transporters such as SLC10A2 as Target to Treat Liver Disease		  
  Francesca Vallese, CUNY ASRC
SLC4A1, the Multitaskerase: from the Ankyrin-1 Complex to CO₂ Transport		  
  Sergei Kutseikin, The Scripps Research Institute
Short Talk: Pharmacological Inhibition of SLC33A1 Redefines Its Role in Endoplasmic Reticulum Redox Balance and Adaptive Signaling		  
  Giovanna Maresca, Axxam SpA
Short Talk: Advancing KCC2 Pharmacological Potentiation: Breaking the State-of-the-Art for CNS Drug Discovery		  
9:00–9:20 AM Coffee Break Beverly Foyer
11:30–12:30 PM Lunch Newburyport
12:30–2:30 PM Networking/Social Time
2:30–4:00 PM Symposia Spotlight 2: Transporters and Cancer Beverly Room
  Lior Golomb, Dana-Farber Cancer Institute, Harvard Medical School
Inactivation of SLC33A1 Sensitizes EGFR Mutant Lung Cancer Cells to Tyrosine Kinase Inhibition		  
  Gregory S. Ducker, University of Utah
An Essential Role for SLC7A5 in Tumor Arginine Metabolism		  
  Rachel (Rae) J House, Van Andel Institute
Defining and Targeting Regulators of Lipid Uptake in Cancer		  
  Meinusha Govindarajan, University of Toronto
Surface Proteomics Reveals SLC7A1 and Arginine Metabolism as a Vulnerability in High Grade Serous Ovarian Cancer		  
  Ruth H. Palmer, University of Gothenburg
Anaplastic Lymphoma Kinase Harnesses the SLC4A7 Bicarbonate Transporter and De Novo Nucleotide Synthesis in Neuroblastoma and Lung Cancer		  
4:00–4:30 PM Coffee Available Beverly Foyer
4:30–6:15 PM Transporters and Drug Discovery Beverly Room
  Kathleen Giacomini, School of Pharmacy, University of California, San Francisco
The Pseudogene Divide in the SLC22 Family: From Orphan Genes to Primate-Specific Functions		  
  Christopher G Parker, The Scripps Research Institute
Chemical Proteomic Approaches to Study Transporters		  
  Ariel Bensimon, Solgate
Accelerating the Discovery of Drug Candidates Against SLCs		  
  Lotte Vanherle, Helmholtz Munich
Short Talk: First-in-Class Small Molecule Inhibitor of SLC13A5 (INDY) Improves MASH, Hepatic Inflammation and Metabolic Dysregulation in Mice and Human Primary Hepatocytes		  
6:15–6:30 PM Meeting Wrap-Up: Outcomes and Future Directions Beverly Room
6:30–9:30 PM Transportation to Town for Dinner Options
Friday, April 17, 2026
12:00–11:59 PM Departure