Vaccinology: A New Era in Immune-Driven Vaccine Design (D3)
May 4-7, 2026  | INEC Killarney Convention Centre, Killarney, KY, Ireland
Galit Alter, Dan H. Barouch, Lynda M. Stuart and Christopher Chiu
Scholarship Deadline: Jan. 8, 2026 | Abstract Deadline: Apr. 14, 2026 | Early Registration Deadline: Mar. 6, 2026
* Session Chair † Invited but not yet accepted | Program current as of February 25, 2026 2 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, May 4, 2026
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, May 5, 2026
7:00–8:00 AM Breakfast
7:30–8:00 AM Poster Setup
7:45–5:00 PM Poster Viewing
8:00–8:10 AM Welcome Remarks
8:10–9:00 AM Keynote Address (Sponsored by Eli Lilly)
  * Karin Bok, Eli Lilly
Chair Introduction
 
  Bali Pulendran, Stanford University School of Medicine
Next Generation Immune Inspired Vaccine Design
 
9:00–11:15 AM How Can We Overcome Waning and Imprinted Immunity?
  Robert A. Seder, NIAID, National Institutes of Health
Anamnestic Immunity - The Key to Durability
 
  Adolfo García-Sastre, Mount Sinai School of Medicine
Breaking the Imprint
 
  Dan H. Barouch, Beth Israel Deaconess Medical Center
Vaccine Immunity to Respiratory Pathogens
 
  Yael Weiss-Ottolenghi †, Sheba Medical Center, Tel-Hashomer, Israel
Short Talk: Profiling the Serological Dynamics Following Seasonal Respiratory Viral Infections in Healthcare Workers
 
9:30–9:50 AM Coffee Break
11:15–12:15 PM Lunch
12:00–2:30 PM Poster Session 1
3:00–4:30 PM Panel 1: Is a One Size Fits All Vaccine Possible for All Populations
  * Galit Alter, AstraZeneca
 
  * Christopher Chiu, Imperial College London
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Dissecting and Harnessing the GC Response?
  Gabriel D Victora, Rockefeller University/HHMI
Refueling germinal center reactions by boosting
 
  Michela Locci, University of Pennsylvania
Dissecting the GC Response
 
  Carola G Vinuesa, Francis Crick Institute
Driving Productive Extra and Intra Follicular B Cell Immunity
 
  Casey Beppler †, Stanford University
Short Talk: Aging Restricts Maturation of CXCL13⁺ Tfh Cells in Human Immunity
 
  Madison L Seefeld †, University of Minnesota
Short Talk: Albumin Hitch-hiking Vaccines for Protection against Herpes Simplex Virus
 
7:00–8:00 PM On Own for Dinner
Wednesday, May 6, 2026
7:00–8:00 AM Breakfast
8:00–11:30 AM How Can We Use Correlates and AI to Accelerate Vaccine Development?
  Galit Alter, AstraZeneca
Advancing Platform Level Correlates of Immunity
 
  John Tsang, Yale University School of Medicine
AI & Systems Immunology for Vaccine Development
 
  Lisa Wagar, University of California, Irvine
Modeling Vaccine Induced Immunity to Drive Vaccine Design
 
  Francis Impens, Ghent University
T Cell Epitope Discovery based AMR Vaccines
 
  Jishnu Das †, University of Pittsburgh
Short Talk: A Systems Approach to Discover Viral Evolutionary Constraints Essential For Hijacking Host Cellular Machinery To Design Broadly Neutralizing Immunotherapies
 
  Marjolein Stip †, RIVM (Dutch Institute for Public Health and Environment)
Short Talk: The Contribution of Pre-existing, Broadly Reactive T cells in Heterosubtypic Protection against A(H1N1)pdm09 Infection in Children
 
  Bryant S Colin †, University of Chicago
Short Talk: Scalable Transcriptional Profiling of CD4+ T Cell States for Vaccine and Adjuvant Discovery
 
  Gitte Erbs †, Statens Serum Institut
Short Talk: Identification of Immunological Correlates of Protection (CoP) in the Helicobacter Pylori Mouse Challenge Model
 
9:00–9:20 AM Coffee Break
9:20–9:25 AM Award Recipient Acknowledgement
11:30–1:00 PM Poster Setup
11:30–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–3:30 PM Career Roundtable
3:30–4:30 PM Panel on Structure-Based Vaccine Design
  Joel Finney †, Boston Children's Hospital
Short Talk: A Public Class of Broadly Protective Human Antibodies that Bind Postfusion Influenza Hemagglutinin
 
  Anna-Sophia Boguraev †, Harvard University
Short Talk: Computationally Designed Scaffolds Present Complex Flavivirus Epitopes
 
  Dieter Sebastian Hoffmann, Leipzig University
Short Talk: Germline-targeting Hepatitis C Virus Immunogens with broad affinity for precursors of AR3C-Class Broadly Neutralizing Antibodies
 
  Danton Ivanochko †, The Hospital for Sick Children
Short Talk: A Stabilized Tandem Antigen Chimera that Elicits Potent Malaria Transmission-Reducing Activity
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM How Can We Exploit New Platforms to Accelerate Vaccine Development and Global Equity?
  Lynda M. Stuart, Fund for Science and Technology (Paul Allen Foundation)
Mimicking Pathogen Shape to Train the Immune Response
 
  Annaliesa S. Anderson, Pfizer, Inc
Next Generation Vaccines for Bacteria
 
  Anna Rydlova †, Imperial College London
Short Talk: Interrogating Humoral Immune Features Beyond O-Antigen–Specific IgG in a Human Non-Typhoidal Salmonella Challenge Model
 
  Courtney R. Plumlee †, Seattle Children's Research Institute
Short Talk: Prevention of Infection in an Ultra-low Dose Tuberculosis Murine Model is a Novel Metric of Vaccine-Mediated Immunity
 
  Luka Cicin-Sain †, Helmholtz Centre for Infection Research
Short Talk: Xenotropic Latency of a Non-replicating Herpesviral Vaccine Vector Elicits Lasting Adaptive Immunity
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Poster Session 2
Thursday, May 7, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Do We Need Tissue Resident Immunity to Achieve Mucosal Protection?
  Christopher Chiu, Imperial College London
The Power of the Human Challenge Model
 
  Daniela M Ferreira, University of Oxford
Dissecting Mucosal Correlates to Bacterial Pathogens
 
  Mihai L Azoitei †, Duke University
AI-Powered Immunogen Design to Target Conserved Regions of Rapidly Evolving Pathogens
 
  Donna L Farber, Columbia University Medical Center
Tissue Resident T Cells across Organs
 
  Haibo Zhang †, Stanford University
Short Talk: Mucosal Vaccination Transcends Pathogen Boundaries to Protect from Diverse Respiratory Threats
 
  Dong-il Kwon †, Yale University, School of Medicine
Short Talk: Clonal Expansion and Trafficking of Memory B Cells Underpin Bone Marrow and Lung IgA+ Plasma Cells following Unadjuvanted Nasal Booster Administration
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
11:30–1:00 PM Poster Setup
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Panel 2: Vaccine Equity and Global Health
  * Lynda M. Stuart, Fund for Science and Technology (Paul Allen Foundation)
 
  * Dan H. Barouch, Beth Israel Deaconess Medical Center
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM How Does Immunology Inform Next Generation Therapeutic Vaccine Design?
  Ari Waisman, University of Mainz, Medical School
Tolerizing Vaccines to Fight Autoimmunity
 
  Michal Bassani-Sternberg, University Hospital of Lausanne, Ludwig Institute for Cancer Research
Inspiring Cancer Vaccine Design with Immunopeptidomics
 
  Meklit Workneh, Moderna
Norovirus Vaccines
 
  Audrey K Thomas, Vanderbilt University
Short Talk: Mucosal Vaccination Clears Clostridioides Difficile Colonization
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Poster Session 3
Friday, May 8, 2026
12:00–11:59 PM Departure