Epigenetics in Health and Disease (D4)
April 12-15, 2027
| Rimrock Banff, Emblems Collection, Banff, AB, Canada
Liling Wan and Bradley E. Bernstein
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–9:00 AM |
Welcome and Keynote Address |
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Clifford P. Brangwynne †, Princeton University
Phase Separation in Genome Regulation |
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| 9:00–11:15 AM |
Genome Architecture in Development and Disease |
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Eileen E.M. Furlong †, European Molecular Biology Laboratory
Enhancer-Promoter Interactions in Development |
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Liling Wan, University of Pennsylvania
Condensates in Genome Organization |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Epigenetic Mechanisms Governing Cell Fate in Health and Disease |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Epigenetic Dysregulation in Cancer: Mechanisms and Therapeutic Targets |
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Margaret A Goodell, Baylor College of Medicine
DNA Methylation in Hematological Malignancies |
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Ali Shilatifard, Northwestern University
Transcriptional Elongation in Health and Disease |
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Pamela Ting †, Novartis Institutes for BioMedical Research
A Molecular Glue Degrader of the WIZ Transcription Factor for Fetal Hemoglobin Induction |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, April 14, 2027
| 8:00–11:00 AM |
Epigenetic Mechanisms of Transcriptional Control |
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Karen Adelman †, Harvard Medical School
Transcriptional Elongation and Enhancer-Promoter Communication |
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Kathrin Plath, University of California, Los Angeles
RNA-Mediated Regulation of Gene Expression |
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Geneviève Almouzni, Centre National de la Recherche Scientifique
Histone Variants in Chromatin Assembly and Genome Stability |
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Bradley E. Bernstein, Dana-Farber Cancer Institute
Functional Epigenomics and Cancer Mechanisms |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–3:00 PM |
Symposia Spotlight 2: Environmental Inputs and Chromatin Dynamics in Physiology and Disease |
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Short Talks Chosen from Abstracts
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Mapping and Perturbing the Epigenome |
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Bing Ren, New York Genome Center and Columbia University
3D Genome and Epigenomic Architecture |
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Charles Gersbach, Duke University
CRISPR-Based Epigenome Editing |
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Alla Sigova †, CAMP4 Therapeutics
RNA Amplifier Therapeutics Targeting Regulatory RNAs to Upregulate Disease-Associated Genes |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Epigenetic Modification Dynamics and Function in Development and Disease |
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Shelley L Berger †, University of Pennsylvania
Histone Modifications in Gene Regulation |
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Wei Xie, Tsinghua University
Transcription Regulation in Early Mammalian Development |
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Asifa Akhtar, Max Planck Institute of Immunobiology and Epigenetics
Dosage Compensation in Development |
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Kristian Helin, The Institute of Cancer Research
Roles of Histone Methylation in Transcription and Development |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 3: Emerging Tools, Technologies, and Therapeutics |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Epigenetic Plasticity in Physiology and Tissue Homeostasis |
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Susan M Kaech †, The Salk Institute
Metabolism, Histone Modifications, and Immunity |
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Justin Brumbaugh, University of Colorado
Epigenetic Regulation in Cell Plasticity and Regeneration in the Intestinal Epithelium |
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Jan Zylicz, University of Copenhagen
Epigenetic and Metabolic Regulation of Early Development |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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