Epigenetics in Health and Disease (D4)
      
      
      
      
      
      April 12-15, 2027
       | Rimrock Banff, Emblems Collection, Banff, AB, Canada
      
      
      
         
          Liling Wan and Bradley E. Bernstein
        
            
      
      
      
          
      
   
            
     
          
    
      
      
        
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 4:00–8:00 PM | 
            Registration | 
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            | 6:00–8:00 PM | 
            Welcome Mixer | 
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            | 8:00–9:00 AM | 
            Welcome and Keynote Address | 
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            |   | 
            Clifford P. Brangwynne †, Princeton University Phase Separation in Genome Regulation | 
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            | 9:00–11:15 AM | 
            Genome Architecture in Development and Disease | 
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            |   | 
            Eileen E.M. Furlong †, European Molecular Biology Laboratory Enhancer-Promoter Interactions in Development | 
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            |   | 
            Liling Wan, University of Pennsylvania Condensates in Genome Organization | 
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            |   | 
            Anders Sejr Hansen †, Massachusetts Institute of Technology High-Resolution 3D Genome Imaging | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 9:30–9:50 AM | 
            Coffee Break | 
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            | 11:15–1:00 PM | 
            Poster Setup | 
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            | 11:15–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–10:00 PM | 
            Poster Viewing | 
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            | 2:30–4:30 PM | 
            Symposia Spotlight 1: Epigenetic Mechanisms Governing Cell Fate in Health and Disease | 
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            Short Talks Chosen from Abstracts
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–7:00 PM | 
            Epigenetic Dysregulation in Cancer: Mechanisms and Therapeutic Targets | 
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            |   | 
            Margaret A Goodell †, Baylor College of Medicine DNA Methylation in Hematological Malignancies | 
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            |   | 
            Ali Shilatifard †, Northwestern University Transcriptional Elongation in Health and Disease | 
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            |   | 
            Pamela Ting †, Novartis Institutes for BioMedical Research A Molecular Glue Degrader of the WIZ Transcription Factor for Fetal Hemoglobin Induction | 
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            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            Wednesday, April 14, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–11:00 AM | 
            Epigenetic Mechanisms of Transcriptional Control | 
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            |   | 
            Karen Adelman †, Harvard Medical School Transcriptional Elongation and Enhancer-Promoter Communication | 
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            |   | 
            Kathrin Plath †, University of California, Los Angeles RNA-Mediated Regulation of Gene Expression | 
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            |   | 
            Geneviève Almouzni †, Centre National de la Recherche Scientifique Histone Variants in Chromatin Assembly and Genome Stability | 
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            |   | 
            Bradley E. Bernstein, Dana-Farber Cancer Institute Functional Epigenomics and Cancer Mechanisms | 
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            Short Talk(s) Chosen from Abstracts
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            | 9:00–9:20 AM | 
            Coffee Break | 
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            | 11:00–1:00 PM | 
            Poster Setup | 
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            | 11:00–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–3:00 PM | 
            Symposia Spotlight 2: Environmental Inputs and Chromatin Dynamics in Physiology and Disease | 
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            Short Talks Chosen from Abstracts
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            | 1:00–10:00 PM | 
            Poster Viewing | 
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            | 3:00–4:30 PM | 
            Career Roundtable | 
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–7:00 PM | 
            Mapping and Perturbing the Epigenome | 
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            |   | 
            Bing Ren †, Ludwig Institute for Cancer Research 3D Genome and Epigenomic Architecture | 
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            |   | 
            Charles Gersbach †, Duke University CRISPR-Based Epigenome Editing | 
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            |   | 
            Alla Sigova †, CAMP4 Therapeutics RNA Amplifier Therapeutics Targeting Regulatory RNAs to Upregulate Disease-Associated Genes | 
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            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            | 8:00–11:00 AM | 
            Epigenetic Modification Dynamics and Function in Development and Disease | 
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            |   | 
            Shelley L Berger †, University of Pennsylvania Histone Modifications in Gene Regulation | 
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            |   | 
            Wei Xie †, Tsinghua University Epigenetic Regulation in Early Development | 
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            |   | 
            Asifa Akhtar †, Max Planck Institute of Immunobiology and Epigenetics Dosage Compensation in Development | 
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            |   | 
            Kristian Helin †, The Institute of Cancer Research Histone Modifying Enzymes Regulators in Cancer | 
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            Short Talk(s) Chosen from Abstracts
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            | 9:00–9:20 AM | 
            Coffee Break | 
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            | 11:00–5:00 PM | 
            On Own for Lunch | 
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            | 2:30–4:30 PM | 
            Symposia Spotlight 3: Emerging Tools, Technologies, and Therapeutics | 
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            |   | 
            Short Talks Chosen from Abstracts
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–7:00 PM | 
            Meeting Wrap-Up: Outcomes and Future Directions | 
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            | 5:00–7:00 PM | 
            Epigenetic Plasticity in Physiology and Tissue Homeostasis | 
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            |   | 
            Susan M Kaech †, The Salk Institute Metabolism, Histone Modifications, and Immunity | 
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            |   | 
            Justin Brumbaugh †, University of Colorado Epigenetic Regulation in Cell Plasticity and Regeneration in the Intestinal Epithelium | 
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            |   | 
            Jan Zylicz †, University of Copenhagen Epigenetic and Metabolic Regulation of Early Development | 
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            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            | 8:00–11:00 PM | 
            Entertainment | 
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