| 4:00–8:00 PM | Registration | INEC Foyer |
| 6:00–8:00 PM | Welcome Mixer | INEC Foyer |
| 7:00–8:00 AM | Breakfast | Individual Hotel |
| 8:00–8:10 AM | Welcome Remarks | INEC Main Auditorium |
| * Karen H. Vousden, Francis Crick Institute |
| * Cynthia L. Sears, Johns Hopkins University School of Medicine |
| * Eileen White, Rutgers Cancer Institute |
| 8:10–9:00 AM | Keynote Address | INEC Main Auditorium |
| * Eileen White, Rutgers Cancer Institute Session Chair |
| Heather Christofk, University of California, Los Angeles Metabolic Transitions in Cancer |
| 9:00–11:15 AM | Systemic Metabolism and Cancer | INEC Main Auditorium |
| * Lydia Lynch, Princeton University Session Chair |
| Craig B Thompson, Memorial Sloan Kettering Cancer Center You Are What You Eat: Membrane Lipids Are an Achilles’ Heel for Kidney Cancer |
| Matthew G Vander Heiden, Massachusetts Institute of Technology The Interplay Between Tumor and Systemic Metabolism |
| Christopher J Halbrook, University of California, Irvine Exploiting Metabolic Vulnerabilities of Chemoresistant Pancreatic Cancer |
| H.Furkan Alkan, UT Southwestern Medical Center Short Talk: Metabolic Regulation of Melanoma Immunogenicity and Metastasis |
| 9:30–9:50 AM | Coffee Break | INEC Foyer |
| 11:15–1:00 PM | Poster Setup | INEC Foyer |
| 11:15–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | INEC Foyer |
| 2:30–4:30 PM | Symposia Spotlight 1: Metabolism and the Immune Response | INEC Main Auditorium |
| * Mariia Yuneva, Calico Life Sciences and Francis Crick Institute Session Chair |
| Julianna Blagih, University of Montreal Short Talk: Fat Length and Timing Matter - Exploiting Saturated Fatty Acids as Cancer Therapy |
| Eveline Barbieri, Baylor College of Medicine Short Talk: Metabolic Competition for Cyst(e)ine Promotes T cell Dysfunction and MYCN-driven Neuroblastoma Tumor Progression |
| Meggie Danielson, University of California Irvine Short Talk: Cytosolic Bacterial Pathogens Activate Innate Immune Pathways in Tumors For Cancer Therapy |
| Alison L. Jaccard, University of Pennsylvania Short Talk: Nutrient-Sensitive Histone Propionylation Regulates T cell Fate and Function |
| Evan C Lien, Van Andel Institute Short Talk: A Low-Fat Diet Improves Cancer Immunotherapy Responses |
| Laura V. Pinheiro, University of Pennsylvania Short Talk: Cancer Cell Insulin Receptor Impairs Anti-Tumor Immunity and Promotes Tumor Growth |
| Viraj Sanghvi, Columbia University Irving Medical Center Short Talk: Lipid Desaturation as a Metabolic Checkpoint for T Cell Immunity in Liver Cancer |
| Vineeth Vengayil, University of Pennsylvania Short Talk: Choline Metabolism Controls Tumor Growth and Myeloid Cell Function in Pancreatic Ductal Adenocarcinoma |
| 4:30–5:00 PM | Coffee Available | INEC Foyer |
| 5:00–7:00 PM | Microbiota, Metabolism and Cancer | INEC Main Auditorium |
| * Marcus D. Goncalves, NYU Langone Session Chair |
| Cynthia L. Sears, Johns Hopkins University School of Medicine Microbiota and Colon Cancer |
| Saman Maleki, Western University Microbiota Engraftment Shapes Toxicity and Clinical Response to Immune Checkpoint Inhibitor Therapy in Metastatic Renal Cell Carcinoma |
| Bertrand Routy, Centre hospitalier de l’Université de Montréal Gut Microbiome and the Efficacy of Cancer Immunotherapy |
| Asael Roichman, Bar Ilan University Short Talk: Dietary Phytochemical-Microbiome Interactions as Determinants of Anticancer Therapy Response |
| Luisa Siegert, Technical University of Munich Short Talk: Refined Diets Trigger Tumor Formation via H2S-producing Desulfovibrio in ATF6-driven Colorectal Cancer |
| 7:00–8:00 PM | Social Hour with Dinner | INEC Foyer |
| 7:30–10:00 PM | Poster Session 1 | INEC Foyer |
| 7:00–8:00 AM | Breakfast | Individual Hotel |
| 8:00–11:00 AM | Metabolic Disease, Aging and Cancer | INEC Main Auditorium |
| * Navdeep S Chandel, Northwestern University Session Chair |
| Ayelet Erez, Weizmann Institute of Science Rewiring Hepatic Metabolism Through Tumor–Host Interactions During Cancer Cachexia |
| Peter James Mullen, University of Southern California Whole Body Metabolism and Cancer Progression |
| Ralph J DeBerardinis, University of Texas Southwestern Medical Center Metabolic Disease and Cancer |
| Karen H. Vousden, Francis Crick Institute Metabolic Control of Cancer Progression |
| David McFadden, UT Southwestern Medical Center Short Talk: Loss of Heterozygosity Exposes Germline Mutations in Complex I that Drive Warburg Metabolism In Oncocytic Carcinoma of the Thyroid |
| Seongmi Russell, Washington University in St. Louis Short Talk: Early-Life Microbial Exposure Reprograms Gut Epithelial Stem Cell Fate to Prime Early-Onset Colorectal Cancer Susceptibility |
| 9:00–9:20 AM | Coffee Break | INEC Foyer |
| 9:20–9:25 AM | Award Recipient Acknowledgement | INEC Main Auditorium |
| 11:00–1:00 PM | Poster Setup | INEC Foyer |
| 11:00–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | INEC Foyer |
| 3:30–4:30 PM | Career Roundtable | INEC Main Auditorium |
| Janhavi Kolhe, Cell Scientific Editor |
| Michaela R Reagan, MaineHealth Institute for Research Faculty Scientist II |
| Petros Tyrakis, Faeth Therapeutics Associate Principal Scientist |
| Triona Ni Chonghaile, Royal College of Surgeons in Ireland Associate Professor |
| 4:30–5:00 PM | Coffee Available | INEC Foyer |
| 5:00–7:00 PM | Antioxidants and Cancer | INEC Main Auditorium |
| * Thales Papagiannakopoulos, NYU School of Medicine Session Chair |
| Scott J Dixon, Stanford University Lipid oxidation and non-apoptotic tumor cell death |
| Richard L. Possemato, New York University School of Medicine Iron Metabolism and Cancer |
| Navdeep S Chandel, Northwestern University Mitochondrial Metabolism, ROS and Cancer |
| Christine Chio, Columbia University Short Talk: Iron-regulated MSRA Methionine Redox Signaling Controls Systemic Metabolism in Cancer and Nutrient Stress |
| Roshni A de Souza, Columbia Unviersity Short Talk: Hypoxia-driven Nucleotide Imbalance Promotes Differentiation in the Colon and Colorectal Cancer |
| 7:00–8:00 PM | Social Hour with Dinner | INEC Foyer |
| 7:30–10:00 PM | Poster Session 2 | INEC Foyer |
| 7:00–8:00 AM | Breakfast | Individual Hotel |
| 8:00–11:00 AM | Cachexia, Obesity and Cancer | INEC Main Auditorium |
| * Peter James Mullen, University of Southern California Session Chair |
| Eileen White, Rutgers Cancer Institute Autophagy, Cachexia and Cancer |
| Lydia Lynch, Princeton University Metabolism, Fat and Cancer |
| Marcus D. Goncalves, NYU Langone Tumor-Body Interactions and Weight Loss |
| Rachel J. Perry, Yale University Obesity, Exercise and Cancer |
| Ana Luiza Labbate Bonaldo, Sao Paulo State University - UNESP Short Talk: Integrated Liver and Muscle Transcriptomics Identify Obesity-Dependent Modulators of Ovarian Cancer Cachexia |
| Alexandra S Ware, University of Chicago Short Talk: BNIP3-Dependent Muscle Atrophy in Cancer Cachexia Promotes PDAC Progression |
| 9:00–9:20 AM | Coffee Break | INEC Foyer |
| 11:00–5:00 PM | On Own for Lunch |
| 2:30–4:30 PM | Symposia Spotlight 2: Understanding Mechanism and Translation for Therapy | INEC Main Auditorium |
| * Richard L. Possemato, New York University School of Medicine Session Chair |
| Michalis Agathocleous, University of Texas Southwestern Medical Center Short Talk: Vitamin C is a Tumor Suppressor Metabolite in Blood Cancers |
| Cian D'Arcy, RCSI Short Talk: Global Proteomic Assessment of a Novel HDAC6 inhibitor and PROTAC in Multiple Myeloma Identify Metabolic Adaptations |
| Keeley G Hewton, University of British Columbia Short Talk: Depletion of Specific Essential Amino Acids Increases Sensitivity to LAT1 Abrogation in Pancreatic Cance |
| Kevin G Hicks, University of Utah Short Talk: Folate Cycle Metabolites Allosterically Regulate Pyruvate Kinase M2 To Modulate Carbohydrate Metabolism |
| Ladan Mashouri, University of Texas at Austin Short Talk: Engineering a Novel Serine-Degrading Enzyme for Targeted Cancer Therapy |
| Michael Noji, University of Pennsylvania Short Talk: Pancreas-specific BCKDK Deficiency Accelerates Pancreatic Neoplasia |
| Cuauhtemoc B Ramirez, University of California, Irvine Short Talk: Understanding and Targeting Essential Amino Acid Metabolism for Treating TSC Kidney Tumors |
| Leah Ziolkowski, The University of Chicago Short Talk: ATF4 Is Required for KRas-Driven Pancreatic Tumorigenesis to Suppress Early-Stage p53 Induction via Effects on 1C Metabolism That Are Rescued by a High Serine Diet |
| 4:30–5:00 PM | Coffee Available | INEC Foyer |
| 5:00–6:45 PM | Cancer, Diet and Therapy | INEC Main Auditorium |
| * Matthew G Vander Heiden, Massachusetts Institute of Technology Session Chair |
| Thales Papagiannakopoulos, NYU School of Medicine Control of Nutrients for Cancer Therapy |
| Mariia Yuneva, Calico Life Sciences and Francis Crick Institute Metabolic Regulation of Aging and Metastasis |
| Oliver Maddocks, University of Glasgow, Faeth Therapeutics Multi-Node Targeting of the PI3K/mTOR Axis in Endometrial and Breast Cancer |
| Yanxiang (Jessie) Guo, Rutgers Cancer Institute Short Talk: Ketogenic Diet Uncovers Genotype-Specific Metabolic and Immune Vulnerabilities in KRAS-Driven Lung Cancer |
| 6:45–7:00 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | INEC Main Auditorium |
| * Cynthia L. Sears, Johns Hopkins University School of Medicine |
| * Eileen White, Rutgers Cancer Institute |
| * Karen H. Vousden, Francis Crick Institute |
| 7:00–8:00 PM | Social Hour with Dinner | INEC Foyer |
| 8:00–9:00 PM | Cash Bar | INEC Foyer |
| 12:00–11:59 PM | Departure |