| 4:00–8:00 PM | Registration | Macdonald Foyer |
| 6:00–8:00 PM | Welcome Mixer | Macdonald Foyer |
| 7:00–8:00 AM | Breakfast | MacDonald CD |
| 7:30–8:30 AM | Poster Setup | MacDonald CD |
| 7:45–7:00 PM | Poster Viewing | MacDonald CD |
| 8:00–9:00 AM | Welcome and Keynote Address | Macdonald AB |
| * Christina Towers, The Salk Institute for Biological Studies Session Chair |
| Anne Simonsen, University of Oslo Intracellular Membrane Trafficking Through Endolysosomes and Autophagy |
| 9:00–11:15 AM | Intersections of Endolysosomes and Autophagy | Macdonald AB |
| * Christina Towers, The Salk Institute for Biological Studies Session Chair |
| * Leon O. Murphy, Casma Therapeutics Session Chair |
| Marja Jäättelä, Danish Cancer Institute Targeting Lysosomal Ion and Lipid Homeostasis in Cancer Treatment |
| Chan Lee, Harvard Medical School Short Talk: TRPML1 Activation Promotes CASM-Dependent Recruitment of DMXL1 to Lysosomes |
| Malene Hansen, Buck Institute for Research on Aging On Canonical and Non-Canonical Autophagy Gene Functions in Aging |
| Rupert Beale, The Francis Crick Institute Non-Canonical Autophagy Mechanisms |
| Thi Phuong Thuy Nguyen, Dana Farber Cancer Institute Women in Autophagy |
| 9:30–9:50 AM | Coffee Break | Macdonald Foyer |
| 11:15–12:15 PM | Lunch | MacDonald CD |
| 11:20–12:20 PM | Women In Science Networking Session | Macdonald AB |
| * Christina Towers, The Salk Institute for Biological Studies Session Chair |
| * Anne Simonsen, University of Oslo Session Chair |
| * Chiara Di Malta, Telethon Institute of Genetics and Medicine Session Chair |
| * Malene Hansen, Buck Institute for Research on Aging Session Chair |
| * Ana Maria Cuervo, Albert Einstein College of Medicine Session Chair |
| * Marja Jäättelä, Danish Cancer Institute Session Chair |
| * Rushika M. Perera, University of California, San Francisco Session Chair |
| 12:00–2:30 PM | Poster Session 1 | MacDonald CD |
| 2:30–4:30 PM | Symposia Spotlight 1: New Insights on Targeting Autophagy and Lysosomes | Macdonald AB |
| * Carmine Settembre, Telethon Foundation Session Chair |
| * Sanjna Singh, South Australian Health and Medical Research Institute Session Chair |
| Joseph D. Mancias, Dana-Farber Cancer Institute Full Talk: Targeting Ferritinophagy in Cancer |
| Swetha Gowrishankar, University of Illinois at Chicago Small Molecule Modulator of Neuronal Lysosome Positioning and Function Resolves Alzheimer’s Disease-Linked Pathologies in Cultured Human Neurons |
| G. Jordan Ray, MIT Lysosomal RNA Profiling Reveals Targeting of Specific Types of RNAs for Degradation |
| Chantell S Evans, Duke University School of Medicine Full Talk: Investigating the Temporal Dynamics of Mitophagy in Neurons |
| Suganthi Chittaranjan, British Columbia Cancer Agency Torin-1 Reduces the Survival Rate of Cells Escaping Combined Treatment with the ATG4B and ATG4A Inhibitor LV320 and Metformin in PDAC Models |
| Matthew Shurtleff, Lycia Therapeutics Catalytic Degradation of Circulating Targets with FcRn-Mediated cycling LYTACs |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Biophysics and Biochemistry of Autophagy | Macdonald AB |
| * Dan Baird, Casma Tx Session Chair |
| * Malene Hansen, Buck Institute for Research on Aging Session Chair |
| Sascha Martens, University of Vienna Mechanisms of Cargo Selection and Autophagosome Biogenesis |
| Jingyue Cassano, University of New Mexico Short Talk: Lysosomes Collaborate with Biomolecular Condensates in Response to Damage |
| James H. Hurley, University of California, Berkeley Mechanisms of Autophagy Initiation |
| Tara D Fischer, National Institutes of Health ATG8 and Ubiquitin Conjugation at Golgi-Related Membranes |
| 7:00–8:00 PM | On Own for Dinner |
| 7:00–8:00 AM | Breakfast | MacDonald CD |
| 8:00–11:00 AM | Disease Relevance and Therapeutic Opportunities: Oncology and Metabolism | Macdonald AB |
| * Joseph D. Mancias, Dana-Farber Cancer Institute Session Chair |
| Christina Towers, The Salk Institute for Biological Studies Targeting Autophagy in Cancer |
| Rushika M. Perera, University of California, San Francisco Lysosomes in Cancer |
| Caleb Cheng, University of Michigan Short Talk: Targeting PIKfyve-Driven Lipid Metabolism in Pancreatic Cancer |
| Noor Gammoh, The University of Edinburgh Autophagy Regulates Oncogenic Signalling |
| Chiara Di Malta, Telethon Institute of Genetics and Medicine TFEB in Metabolic Growth Disorders |
| Sharon Gorski, BC Cancer Research Institute Short Talk: Suppression of Autophagy and PARP1 Activity by Dual Loss of Caspase 3 and Caspase 7 |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 9:20–9:25 AM | Award Recipient Acknowledgement | Macdonald AB |
| 11:00–1:00 PM | Poster Setup | MacDonald CD |
| 11:00–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | MacDonald CD |
| 3:30–4:30 PM | Career Roundtable | Macdonald AB |
| Christina Towers, The Salk Institute for Biological Studies Assistant Professor |
| Dan Baird, Casma Tx VP of Molecular Biology |
| Andrea Marat, Journal of Cell Biology Deputy Editor |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Disease Relevance and Therapeutic Opportunities: Neurodegeneration | Macdonald AB |
| * Chantell S Evans, Duke University School of Medicine Session Chair |
| * Monther Abu-Remaileh, Stanford University Session Chair |
| Yvette C. Wong, Northwestern University Inter-Organelle Lysosome Contact Sites in Health and Neurodegeneration |
| Mathieu Bourdenx, University College London Short Talk: Subcellular Proteomics Identify a Late-Endosome-Specific Signature Predicting Alzheimer's Disease Progression |
| Beat Nyfeler, Novartis Biomedical Research Identification of Entry Points for Autophagy-Mediated Targeted Protein and Organelle Degradation using an Induced-Proximity Screen |
| Claire E Richardson, UW Madison Short Talk: TFEB/HLH-30-Mediated Expansion of Neuronal Lysosomal Capacity in Early Adulthood Maintains Dendrite Morphology and Neurotransmission During Caenorhabditis Elegans Aging |
| Juan S. Bonifacino, National Institutes of Health AP-4 Delivers Autophagy Effectors from the TGN to Phagophore Assembly Sites |
| 7:00–8:00 PM | Social Hour with Lite Bites | MacDonald CD |
| 7:30–10:00 PM | Poster Session 2 | MacDonald CD |
| 7:00–8:00 AM | Breakfast | MacDonald CD |
| 8:00–11:00 AM | Disease Relevance and Therapeutic Opportunities: Infection and Immunity | Macdonald AB |
| * James H. Hurley, University of California, Berkeley Session Chair |
| * Tara D Fischer, National Institutes of Health Session Chair |
| Feng Shao, National Institute of Biological Sciences The Role of Autophagy Machinery in Anti-Bacterial Mechanisms |
| Maximiliano Gutierrez, Francis Crick Institute Xenophagy: Implications for Tuberculosis |
| Damian Gatica, University of Ottawa Short Talk: The ER-Phagy Receptor FAM134B/RETREG1 is Targeted by Salmonella Typhimurium to Promote Infection |
| James Phelan, National Cancer Institute Autophagic Control of Oncogenic Signaling in Lymphoma |
| Kathryn Jacobs, VIB center for cancer biology Short Talk: Autophagy as a Key Regulator of High Endothelial Venule Identity and Function During Inflammation |
| Corey N Cunningham, University of Utah Short Talk: The Orphan Transporter SLC16A6 is Required For Melanogenesis And Lysosomal Acidification |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 11:00–11:15 AM | Autophagy and Autophagy Reports Poster Award | Macdonald AB |
| 11:00–2:15 PM | On Own for Lunch |
| 2:15–4:30 PM | Symposia Spotlight 2: Novel Techniques and Models to Interrogate Autophagosomes and Endolysosomes | Macdonald AB |
| * Maximiliano Gutierrez, Francis Crick Institute Session Chair |
| * Adam L Yokom, University of Missouri Session Chair |
| Oluwatobi A Adeosun, University of Osnabrueck Transbilayer Lipid Dynamics and Signaling in Lysosomal Repair |
| Monther Abu-Remaileh, Stanford University Full Talk: Unlocking The Secrets of the Lysosome in Neurodegeneration: From Tool Development to Novel Biology and Back |
| Elizabeth Delorme-Axford, Oakland University The Nonsense-Mediated mRNA Decay Factor Upf3 is a Negative Regulator of Autophagy in Yeast |
| Michael A Mandell, University of New Mexico School of Medicine TRIM46 maintains microtubule organization to restrain Golgi atg8ylation and lysosomal biogenesis |
| Karyn King, University of Ottawa Discovery of Regulatory Pathways for CASM |
| Tara Tigani, Peter MacCallum Cancer Centre Employing a Metabolism Focused CRISPR Screen to Identify Novel Regulators of Lysosomal Biogenesis |
| Samit Desai, University of Basel Mitochondria-ER Contact Sites Facilitate Endocytic Lysosomal Reformation Via DRP1-Dependent Fission |
| Rhiannon Brown, University of Sheffield Stratifying Sporadic Parkinson’s Disease Patients Based on Mitochondrial and Lysosomal Dysfunction |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–6:45 PM | What Don't We Know About the Autophagy Pathway | Macdonald AB |
| * Rupert Beale, The Francis Crick Institute Session Chair |
| * Anne Simonsen, University of Oslo Session Chair |
| Leon O. Murphy, Casma Therapeutics Targeting Autophagy: Where the Field Has Been and Where is it Going |
| Timothy Sargeant, SAHMRI Short Talk: Physiological Human Autophagy Increases in the PBMC Pool In Human Ageing And Human Age-Related Disease |
| Ana Maria Cuervo, Albert Einstein College of Medicine Chaperone Mediated Autophagy: Where the Field has Been and Where is it Going? |
| Noboru Mizushima, University of Tokyo Autophagy in the nervous system: Where the Field has Been and Where is it Going? |
| 6:45–7:00 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | Macdonald AB |
| 7:00–8:00 PM | Social Hour with Lite Bites | MacDonald CD |
| 8:00–9:00 PM | Entertainment | Macdonald AB |
| 8:00–9:00 PM | Cash Bar | MacDonald CD |
| 12:00–11:59 PM | Departure |