| 4:00–8:00 PM | Registration | Macdonald Foyer |
| 6:00–8:00 PM | Welcome Mixer | Macdonald Foyer |
| 7:00–8:00 AM | Breakfast | Macdonald CDEF |
| 8:00–8:10 AM | Welcome Remarsk | Macdonald B |
| 8:10–9:00 AM | Keynote Address | Macdonald B |
| Roy Kishony, Technion – Israel Institute of Technology The Future of Antibiotic Resistance |
| 9:00–11:00 AM | Translating Antibiotics into the Clinic: Obstacles and Opportunities | Macdonald B |
| Man-Wah Tan, Genentech, Inc. Novel Inhibitors against Gram-negative Pathogens |
| Speaker to be Announced |
| David Payne, GlaxoSmithKline Antibiotic Discovery and Development at GSK |
| 9:30–9:50 AM | Coffee Break | Macdonald Foyer |
| 11:10–11:40 AM | Panel Discussion 1: Q&A with Drs. Tan and Payne | Macdonald B |
| 11:40–1:00 PM | Poster Setup | Macdonald CDEF |
| 11:40–2:30 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Macdonald CDEF |
| 2:30–4:30 PM | Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions | Macdonald B |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–6:45 PM | Antibiotics AI: Computational & AI-Enabled Antibiotic Discovery | Macdonald B |
| James J. Collins, Broad Institute of MIT & Harvard AI Approaches for Antibiotic Discovery |
| Cesar de la Fuente, University of Pennsylvania Accelerating Antibiotic Discovery Using AI |
| Ewa Szczurek, Helmholtz Munich Controllable Generative AI for Antimicrobial Peptides Discovery |
| Short Talk(s) Chosen from Abstracts |
| 6:55–7:25 PM | Panel Discussion 2: Q&A with Drs. Collins, de la Fuente and Szczurek | Macdonald B |
| 7:25–8:25 PM | Social Hour with Dinner | Macdonald CDEF |
| 7:30–10:00 PM | Poster Session 1 | Macdonald CDEF |
| 7:00–8:00 AM | Breakfast | Macdonald CDEF |
| 8:00–11:00 AM | Natural-Product Biosynthesis and Engineering | Macdonald B |
| Gerry D. Wright, McMaster University New Natural Product Antibiotics |
| Allison Lopatkin, University of Rochester Predictive Biology: Understanding and Reversing the Evolution of Antibiotic Resistance |
| Short Talk(s) Chosen from Abstracts |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 11:10–12:10 PM | Roundtable Discussion: The Next Generation of Antibiotic Hunters (inspiring new people into the field) | Macdonald B |
| Paul E. Turner, Yale University |
| 12:10–1:00 PM | Poster Setup | Macdonald CDEF |
| 12:10–3:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Macdonald CDEF |
| 3:00–4:30 PM | Career Roundtable (Joint) | Macdonald A |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Antibiotic Discovery and Host Immunity | Macdonald B |
| Yifat Merbl, Weizmann Institute of Science Proteasome-Derived Defense Peptides (PDDPs): An Untapped Source of Antimicrobial Agents |
| Olga Shevchuk, University Hospital Essen Production of Encrypted Antibiotics in Human Kidney Infections |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner | Macdonald CDEF |
| 7:30–10:00 PM | Poster Session 2 | Macdonald CDEF |
| 7:00–8:00 AM | Breakfast | Macdonald CDEF |
| 8:00–11:00 AM | Frontiers in Non-Traditional Antimicrobials: Phages, Vaccines, Peptides & Beyond | Macdonald B |
| Paul E. Turner, Yale University Phage Therapy to Combat Infections by Antibiotic-Resistant Bacterial Pathogens |
| Rino Rappuoli, Fondazione Biotecnopolo di Siena Vaccines against AMR |
| Renee Fleeman, University of Central Florida Peptide Dual Targeting of Membrane and Ribosomes disrupts biofilm formation and prevents in vivo dissemination |
| Short Talk(s) Chosen from Abstracts |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 11:00–2:30 PM | On Own for Lunch |
| 2:30–4:30 PM | Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions | Macdonald B |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–6:30 PM | Alternative Approaches to Antibiotics | Macdonald B |
| Manuela Raffatellu, University of California, San Diego Harnessing Iron Acquisition Machinery to Target Pathogens |
| Victor Torres †, St. Jude Children's Research Hospital Novel Approaches Against Staphylococcus Aureus Infections |
| Jörg Vogel, University of Würzburg The Promises and Challenges of Programmable RNA Antibiotics |
| 6:30–7:30 PM | Machine Learning and Antimicrobial Peptides | Macdonald B |
| Jiangning Song, Monash University Machine Learning for Antimicrobial Peptide Design and Discovery |
| Daniela Kalafatovic, University of Rijeka Self-Assembling Peptide Design with Generative AI |
| 7:30–7:45 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | Macdonald B |
| 7:45–8:45 PM | Social Hour with Dinner | Macdonald CDEF |
| 8:00–11:00 PM | Cash Bar |
| 8:00–11:00 PM | Entertainment |
| 12:00–11:59 PM | Departure |