Next-Generation Nanomedicine (EK1)
September 6-8, 2023
| Virtual Conference
Philip L. Felgner, Anna K. Blakney and Norbert Pardi
| Abstract Deadline: Aug. 30, 2023
Wednesday, September 6, 2023
| 3:00–3:30 AM |
Welcome and Keynote Address |
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Pieter Cullis, University of British Columbia
Rational Design of Lipid Nanoparticle Delivery Systems for Nucleic Acid-Based Drugs |
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| 3:30–6:00 AM |
Challenges in Anatomical and Physiological Nanomedicine Delivery |
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Jayesh Kulkarni, NanoVation Therapeutics
Universal Delivery |
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Daniel J. Siegwart, University of Texas Southwestern Medical Center
Multiplexed SORT LNPs for Enhancing CRISPR/Cas Gene Editing Cancer Therapy through Modulating Tumor Mechanical Properties |
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James Dahlman, Georgia Tech / Emory Medical School
LNP Barcoding |
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Kathryn Whitehead, Carnegie Mellon University
From Farm to Pharmacy: A Strawberry-Derived Solution to Oral Protein Delivery |
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Maria José Alonso, University of Santiago de Compostela
Nanoemulsions vs. LNPs for RNA Delivery |
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| 8:00–9:00 AM |
Poster Session |
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| 9:30–12:30 PM |
Immunoengineering in Nanomedicine |
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Parinaz Fathi, NIBIB, National Institutes of Health
Biologically-Derived Nanomaterials |
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Jeffrey A. Hubbell, University of Chicago
Engineering Polymer Conjugates and Protein Fusions for Immune Modulation |
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Jessica Weaver, Arizona State University
Placenta-Iinspired Approaches to Engineering Immune Tolerance |
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Thursday, September 7, 2023
| 3:00–3:30 AM |
Keynote Address |
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Drew Weissman, University of Pennsylvania
Nucleoside Modified mRNA-LNP Therapeutics |
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| 3:30–5:45 AM |
AI and Big Data in Nanomedicine / Progress in RNA Vaccines I |
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Daniel Reker, Duke University
Machine Learning for Self-Assembling Nanoparticles |
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Ramya Kumar, Colorado School of Mines
Machine Learning for Nucleic Acid Delivery |
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| 8:00–9:00 AM |
Career Roundtable |
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Denise Hsu, Moderna
Director, Clinical Development, Infectious Diseases |
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| 9:30–12:30 PM |
Progress in RNA Vaccines II |
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Mustafa Diken, BioNTech
mRNA Vaccines against Cancer |
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Philip L. Felgner, University of California, Irvine
150 Years of Vaccine Science |
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Michela Locci, University of Pennsylvania
Immunological Mechanisms of mRNA-LNP Vaccines |
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Norbert Pardi, University of Pennsylvania
Development of Broadly Protective Influenza Vaccines Using Nucleoside-Modified mRNA |
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Denise Hsu, Moderna
Moderna Seasonal Influenza Vaccine Portfolio |
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Friday, September 8, 2023
| 3:00–6:00 AM |
Applications of RNA Beyond Vaccines |
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Anna K. Blakney, University of British Columbia
Optimizing Self-Amplifying RNA Vectors for Applications Beyond Vaccines |
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Jesse Erasmus, HDT Bio / University of Washington
Enabling High-Dose Administration of Replicating mRNA for Multivalent Vaccination and Therapeutic Applications |
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Zoltan Jakus, Semmelweis University
Treatment of Lymphedema with VEGFC mRNA |
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Valerie Gouon-Evans, Boston University
Treatment of Liver Diseases with mRNA Encoded Factors |
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| 9:30–12:30 PM |
Delivery Technologies |
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Cyrus Safinya, University of California, Santa Barbara
Fluid Lipid Nanodiscs and Exosome Derived Vectors in Delivery Applications |
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Krzysztof Palczewski, University of California, Irvine
Precision Genome Editing in the Eye |
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Suzie Pun, University of Washington
Cytosolic Delivery of Macromolecules: Vehicle Design and Lessons Learned in Delivery Limitations |
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