Long COVID and Other Post-Acute Infection Syndromes (F1)
August 10-13, 2025  | Eldorado Hotel & Spa, Santa Fe, NM, United States
Akiko Iwasaki, Avindra Nath, Hannah Davis and Daniel M. Altmann
Scholarship Deadline: May. 28, 2025 | Abstract Deadline: Jul. 18, 2025 | Early Registration Deadline: Jun. 25, 2025
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 4 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, August 10, 2025
4:00–8:00 PM Registration Concourse
6:00–8:00 PM Welcome Mixer Cava Santa Fe
Monday, August 11, 2025
7:00–8:00 AM Breakfast Anasazi Ballroom
7:30–8:00 AM Poster Setup Anasazi Ballroom
7:30–5:00 PM Poster Viewing Anasazi Ballroom
8:00–9:00 AM Welcome and Keynote Address Eldorado Ballroom
  * Akiko Iwasaki, Yale University/HHMI
 
  Michael J Peluso, University of California, San Francisco
Long COVID: What We have Learned so far and What Needs to Happen Next
 
9:00–11:15 AM Epidemiology, Clinical Diagnosis and Management of Long COVID Eldorado Ballroom
  * Hannah Davis, Patient-Led Research Collaborative
Two patterns in Long Covid: Craniocervical Instability and Illness Duration
 
  Ziyad Al-Aly, Washington University School of Medicine
Epidemiology of Long COVID
 
  David Putrino, Mount Sinai School of Medicine
Clinical Diagnosis and Management of Long COVID
 
  Michelle J L Scoullar, Burnet Institute
Short Talk: A Narrative Review of the Impact, Treatment and Outcomes of Paediatric Long COVID, Including the Prevalence of Dysautonomia, From A Specialist Long COVID Clinic in Australia
 
9:30–9:50 AM Coffee Break Concourse
11:15–12:15 PM Lunch Anasazi Ballroom
11:20–12:15 PM Women in Science Networking Session Eldorado Ballroom
  * Emma C Wall, The Francis Crick Institute
 
  * Nadia R. Roan, University of California, San Francisco
 
  * Esther Melamed, Dell Medical School
 
  * Hanna Ollila, University of Helsinki and Harvard University
 
  * Courtney Malo, Science Translational Medicine
 
11:45–2:15 PM Poster Session 1 Anasazi Ballroom
2:15–4:30 PM Symposia Spotlight: Featured Abstract Presentations Eldorado Ballroom
  Amelie Bos, University Medical Centre Amsterdam
An In Vitro Model for Long-COVID Using Skeletal Muscle Cultures and Patient Plasma
 
  * Timothy J. Henrich, University of California, San Francisco
Multi-Omic Analysis of Bone Marrow from People with and Without Long COVID Reveals Lymphoproliferative Disorders and Immune Dysregulation but Not SARS-CoV-2 Persistence
 
  Penelope Markham, BioVie
A Phase 2 Trial Designed to Enhance Signal Detection in an Evaluation of Bezisterim (NE3107) For the Treatment of Neurological Symptoms of Long COVID
 
  Claire S Laxton, Yale University
Development of a Multiplex qPCR To Detect Herpesvirus Reactivation and Shedding Dynamics in Saliva of Long Covid Patients
 
  Emma C Wall, The Francis Crick Institute
An Innate Inflammatory Signature Is Consistently Enriched in the Plasma of Adults Living with Long COVID Across all Clinical Symptom Groups
 
  Nadia R. Roan, University of California, San Francisco
Inhibition of CXCR4 Signaling Reverses Behavioral Abnormalities in a Mouse Model of Long COVID
 
  Esther Melamed, Dell Medical School
Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies
 
  Michela Locci, University of Pennsylvania
Alterations of B Cell Responses to SARS-CoV-2 in Long COVID
 
  Hung-Jen Chen, University of Amsterdam, Amsterdam University Medical Centers
Long COVID and Autoimmunity: Transfer of IgG from Long COVID Patients Induces Symptomology in Mice
 
4:30–5:00 PM Coffee Available Concourse
5:00–7:00 PM Immunological Dysfunction and Mechanisms of Long COVID Eldorado Ballroom
  * Daniel M. Altmann, Imperial College London
Immune Signatures of Long COVID
 
  E. John Wherry, University of Pennsylvania
Using T Cells as Biosensors in Long COVID
 
  Akiko Iwasaki, Yale University/HHMI
Immunological Mechanisms of Long COVID
 
  August Jernbom, KTH Royal Institute of Technology / Johns Hopkins University
Short Talk: Prevalent and Persistent New-Onset Autoantibodies in Mild to Severe COVID-19
 
  Shubha Talwar, Imperial College London
Short Talk: Investigating the Role of Autoantibodies in Long-Lasting Respiratory Symptoms Post-COVID-19
 
7:00–8:00 PM On Own for Dinner
Tuesday, August 12, 2025
7:00–8:00 AM Breakfast Anasazi Ballroom
8:00–10:30 AM Post-Acute Infection Syndromes Eldorado Ballroom
  Lisa F.P. Ng, Infectious Diseases Labs, ASTAR
Post-Chikungunya Virus Autoimmune Syndrome
 
  * Michal Caspi Tal, Massachusetts Institute of Technology
Unraveling the Immunopathology of Borrelia Infection-Associated Chronic Illnesses: Sex Differences and Predictive Diagnostics
 
  Maureen R. Hanson, Cornell University
Immune Signaling in ME/CFS
 
  Jalene Velazquez, Washington State University
Short Talk: Distinct Antibody Effector Profiles Track with the Development of Post-Ebola Syndrome
 
  Maia M Madison, UCSF
Short Talk: Cytokine Biomarkers for Differential Diagnosis of Persistent Lyme Disease and Other Infection-Associated Chronic Illnesses
 
9:00–9:20 AM Coffee Break Concourse
9:20–9:25 AM Award Recipient Acknowledgement Eldorado Ballroom
10:30–1:00 PM Poster Setup Anasazi Ballroom
10:30–3:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Anasazi Ballroom
1:45–2:45 PM Career Roundtable Eldorado Ballroom
  Roshan Kumar, HiFiBiO Therapeutics
Executive Director, Head of Research and External Innovation
 
  Vidhya Vijayakumar, Draper Labs
Principal Member of Technical Staff
 
  Annukka A Antar, Johns Hopkins School of Medicine
Assistant Professor
 
3:00–4:30 PM Panel Discussion: Long COVID: Mechanisms, Diagnosis, and Emerging Treatments Eldorado Ballroom
  * Maggie Bartlett, Global Virus Network & Johns Hopkins School of Public Health
Moderator
 
  * Sten H. Vermund, University of South Florida
Moderator
 
  Akiko Iwasaki, Yale University/HHMI
 
  Anders G. Vahlne, Karolinska Institutet
 
  Resia Pretorius, Stellenbosch University
 
  Janet M Mullington, BIDMC & Harvard Medical School
 
  Annukka A Antar, Johns Hopkins School of Medicine
 
4:30–5:00 PM Coffee Available Concourse
5:00–7:00 PM Gut, Sex and other Influences on the Manifestation of PAIS Eldorado Ballroom
  Sabra L. Klein, Johns Hopkins University
Remote Presentation: Sex Differences in Long COVID Revealed by Animal Models
 
  * Maayan Levy, Stanford University
The Role of Persistent Gut Infection in Long COVID
 
  Vivian Vasconcelos C Litwinski, Federal University of Minas Gerais
After the Virus: Mechanisms Driving Post-Viral Sequelae
 
  Brian H LaFranchi, UCSF
Short Talk: Deep Multi-Omic Analysis of Colorectal Tissues from People with and Without Long COVID Demonstrates SARS-CoV-2 Persistence and Immune Dysregulation Years After Initial Infection
 
  James Chung, University of Missouri
Short Talk: Facilitating Mouse Studies of Long COVID
 
7:00–8:00 PM Social Hour with Dinner Anasazi Ballroom
7:30–10:00 PM Poster Session 2 Anasazi Ballroom
Wednesday, August 13, 2025
7:00–8:00 AM Breakfast Anasazi Ballroom
8:00–11:00 AM Neurological and Vascular Damages in Long COVID Eldorado Ballroom
  Petter Brodin, Karolinska Institutet
Viral Persistence and Regulation of Immunity in PACS
 
  * Avindra Nath, NINDS, National Institutes of Health
Neurological Complications in Long COVID and ME CFS
 
  Jennifer Frontera, New York University
Neurodegenerative Diseases Following COVID-19
 
  Joga R. Chaganti, Thomas Jefferson University Hospital
Imaging Correlates of Dysfunction in Glymphatic System, Blood Brian Barrier and Explore Glutamatergic Excitotoxicity in Long Covid
 
  Lindsay McAlpine, Yale University School of Medicine
Short Talk: Cerebrospinal Fluid Alterations & Proteomics in Neuropsychiatric Long COVID
 
  Alba Azola, Johns Hopkins School of Medicine
Short Talk: Blood-Brain Barrier Disruption in Long COVID and Cognitive Correlates
 
9:00–9:20 AM Coffee Break Concourse
11:00–1:00 PM Poster Setup Anasazi Ballroom
11:00–2:15 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Anasazi Ballroom
2:30–4:30 PM Understudied Topics in PAIS Eldorado Ballroom
  Roshan Kumar, HiFiBiO Therapeutics
T Cell Dysregulation Revealed by Single-Cell TCR Repertoire & Expression Profiling of Long COVID and ME/CFS Patients
 
  Hideki Ueno, Graduate School of Medicine, Kyoto University
Sex Differences in Immune Responses Shape Long COVID Pathogenesis
 
  Cherie L Marvel, Johns Hopkins University
Functional brain imaging and outcomes in long COVID and post treatment Lyme disease
 
  Paige Hansen Colburn, Massachusetts Institute of Technology
Lyme Disease Increases Risk for Multiple Gynecological Conditions
 
  * John N Aucott, Johns Hopkins University
The Concurrence of Post-Treatment Lyme Disease, Fibromyalgia, and ME/CFS
 
  Bronwyn M Gunn, Washington State University
Humoral Immune Correlates of Orthoebolavirus Sudanese RNA Persistence in Semen
 
  Abigail Vanderheiden, Washington University in St. Louis
Dural CD4+ T Cells Promote Hippocampal Memory Deficits in a Mouse Model of COVID-19
 
  Bornali Bhattacharjee, Yale University
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination
 
4:30–5:00 PM Coffee Available Concourse
5:00–6:15 PM Clinical and Translational Approaches in PAIS Eldorado Ballroom
  * E. Wesley Ely, Vanderbilt University Medical Center
Reverse-LC Baricitinib Trial for Long COVID
 
  Amitava Banerjee, University College London
Insights from STIMULATE-ICP
 
  Giulia Unali, Boston University
Short Talk: Bone Marrow Hematopoietic Impairment in a Humanized Mouse Model of Post-acute Sequelae of COVID-19
 
6:15–6:30 PM Meeting Wrap-Up: Outcomes and Future Directions Eldorado Ballroom
6:30–7:30 PM Social Hour with Dinner Anasazi Ballroom
7:30–10:00 PM Poster Session 3 Eldorado Ballroom
Thursday, August 14, 2025
12:00–11:59 PM Departure