Integrative Structural Biology: Bridging Fields, Techniques, and Scales (F1)
September 28-October 1, 2026 | Village at Breckenridge, Breckenridge, CO, United States
Alex de Marco, Giulia Palermo and Niccolò Banterle
Scholarship Deadline: Jul. 15, 2026 | Abstract Deadline: Sep. 9, 2026 | Early Registration Deadline: Jul. 31, 2026
Monday, September 28, 2026
| 4:00–8:00 PM |
Registration |
Atrium Lobby |
| 6:00–8:00 PM |
Welcome Mixer |
Forest Ballroom and Lounge |
Tuesday, September 29, 2026
| 7:00–8:00 AM |
Breakfast |
Forest Ballroom and Lounge |
| 8:00–8:10 AM |
Welcome Remarks |
Elevation Ballroom |
| 8:10–9:00 AM |
Keynote Address |
Elevation Ballroom |
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James S Fraser, University of California, San Francisco
Statistical Structural Biology |
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| 9:00–11:15 AM |
Integrating Multiscale Microscopy |
Elevation Ballroom |
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Alex de Marco, New York Structural Biology Center
Visual Proteomics, from Data to Virtual Cells |
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Lindsey Young, University of California, San Diego
Expanding the Toolkit for Structural Cell Biology |
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Agnieszka Obarska-Kosinska, Max Planck Institute of Biophysics
Structural Modeling of Nuclear Pore Complexes |
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William Conway, Flatiron Institute
Short Talk: Multiscale, Local Self-Organization of the Human Metaphase Mitotic Spindle |
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| 9:30–9:50 AM |
Coffee Break |
Elevation Foyer |
| 11:25–12:25 PM |
Meet the Editors |
Elevation Ballroom |
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Katarzyna M. Marcinkiewicz, Nature Communications
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| 12:25–1:00 PM |
Poster Setup |
Atrium Lobby |
| 12:25–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Atrium Lobby |
| 2:30–4:30 PM |
Symposia Spotlight: Machines, Membranes, and Molecular Recognition |
Elevation Ballroom |
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Md Ashaduzzaman †, UC Davis
Short Talk: Mechanism of Heterotrimeric Kinesin-2 Autoinhibition and Cargo-mediated Activation |
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Walter J Chazin, Vanderbilt University
Short Talk: Capturing Active Nucleotide Excision Repair Machinery As It Assembles, Scans and Verifies Lesions |
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Kitaik Lee †, St. Jude Children's Research Hospital
Short Talk: In Situ Photo-Crosslinking and Cryo-EM Reveal a Transient PSMD5/S5b Chaperone State of the Proteasome |
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Zhicheng Cui, University of Colorado Anschutz Medical Campus
Short Talk: Structural Basis of PI3P Recognition and Membrane Remodeling by the DFCP1 Oligomer during Autophagy Initiation |
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Alys A Peisley †, University of Michigan
Short Talk: Cryo-EM Structures of Kir7.1 Reveal the Molecular Mechanisms of Gating and ML418 Blockade |
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Harsh Bansia †, New York University
Short Talk: Structural Basis for NGF/TrkA Blockade by Analgesic Antibodies |
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Alesandro Civljak †, Icahn School of Medicine at Mount Sinai
Short Talk: Cryo-EM Reveals a Structural Mechanism of Polyvalent Engagement of the Peanut Allergen Ara h 2 by a Class of Pathogenic IgE Antibodies |
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Diego Suchenski Loustaunau, Yale University
Short Talk: PORECAST: Deep Learning Segmentation of Nuclear Pore Complexes and Nuclei to Map Local Nuclear Envelope Tension in Cells and Tissues |
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| 4:30–5:00 PM |
Coffee Available |
Elevation Foyer |
| 5:00–7:00 PM |
Integrating Data Generation and Computational Approaches |
Elevation Ballroom |
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Kevin H Gardner, CUNY Advanced Science Research Center
Lighting the Way: Integrative Structural Biology Studies of Photosensors in Action |
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Alisha Jones, New York University
Integrative Structural and Computational Biology for RNA Discovery |
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Pilar Cossio, Flatiron Institute
Inferring Probability Distributions of RNAs using Cryo-EM Images |
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Christopher JF Cameron, New York Structural Biology Center
Short Talk: Real-Time Movie Triage for Early Quality Control in Cryo-EM |
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Abhilash Sahoo, Simons Foundation
Short Talk: A Physics-Based Framework for Predicting and Controlling Preferred Orientation in Cryo-EM |
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| 7:00–8:00 PM |
Social Hour with Dinner |
Forest Ballroom and Lounge |
| 7:30–10:00 PM |
Poster Session 1 |
Atrium Lobby |
Wednesday, September 30, 2026
| 7:00–8:00 AM |
Breakfast |
Forest Ballroom and Lounge |
| 8:00–11:00 AM |
Computational Approaches and Data Integration |
Elevation Ballroom |
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Karissa Y. Sanbonmatsu, Los Alamos National Laboratory
Multiscale Modeling of Biological Systems: Integrating Structural and Dynamic Information |
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Giulia Palermo, University of California Riverside
Advancing Gene Editing through Computational Models and Deep Learning |
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Uriel Morzan, Universidad de Buenos Aires
Unsupervised Learning Approaches in Molecular Dynamics towards Understanding Allostery and Protein Regulation |
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Ivaylo Ivanov †, Georgia State University
Short Talk: Molecular Model of TFIIH Recruitment to the Transcription-coupled Repair Machinery |
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Piotr Chyzy, University of Warsaw
Short Talk: Catching a Riboswitch in the Act: Multidimensional Simulations of Aminoglycoside Recognition |
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Shivam Pandit †, The University of Tennessee, Knoxville
Short Talk: Integrative Simulation and Neutron Scattering Analysis of Sequence-Encoded Phase Separation in Plant IDPs |
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| 9:00–9:20 AM |
Coffee Break |
Elevation Foyer |
| 9:20–9:25 AM |
Award Recipient Acknowledgement |
Elevation Ballroom |
| 11:00–1:00 PM |
Poster Setup |
Atrium Lobby |
| 11:00–3:30 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Atrium Lobby |
| 3:30–4:30 PM |
Career Roundtable |
Elevation Ballroom |
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Edward Eng, New York Structural Biology Center
Senior Scientist |
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| 4:30–5:00 PM |
Coffee Available |
Elevation Foyer |
| 5:00–7:00 PM |
Structural Dynamics |
Elevation Ballroom |
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Hashim M. Al-Hashimi, Columbia University
Predicting RNA Cellular Activity from Sequence via Conformational Ensembles |
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George Lisi, Brown University
Atomic Details at the Intersection of Allostery, Specificity, and Inhibition of CRISPR-Cas Systems |
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Cesar de la Fuente, University of Pennsylvania
Accelerating Biological Discovery with AI |
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Jose Rodriguez, University of California, Los Angeles
Surveillance of Amyloid Structure and Function, from Atoms to Cells |
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| 7:00–8:00 PM |
Social Hour with Dinner |
Forest Ballroom and Lounge |
| 7:30–10:00 PM |
Poster Session 2 |
Atrium Lobby |
Thursday, October 1, 2026
| 7:00–8:00 AM |
Breakfast |
Forest Ballroom and Lounge |
| 8:00–11:00 AM |
Visualizing Correlative Datasets |
Elevation Ballroom |
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Niccolò Banterle, European Molecular Biology Laboratory
Structural Cell Biology at the Mesoscale |
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Fan Liu, Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Illuminating Drug-Target Interactions: Integrating Structural Biology and Advanced Proteomics |
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Simon Scheuring, Weill Cornell Medicine
High-Speed Atomic Force Microscopy: Visualizing Biomolecular Structure-Dynamics in Real-Time |
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Jessie James L Malit, ETH Zurich
Short Talk: Uncovering the Cell Surface of Asgard Archaea |
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Maxim B Prigozhin, Harvard University
Short Talk: Dynamic and Multicolor Electron Microscopy |
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Vineeta Kaushik †, ICTER, IChf, Warsaw Poland
Short Talk: PDE6 Conformational Dynamics as a Molecular Driver of Light-Induced Photoreceptor Length Modulation |
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Rachael Kretsch †, Stanford University
Short Talk: High Throughput and In Situ Interrogation of Large ncRNA RNA Families |
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| 9:00–9:20 AM |
Coffee Break |
Elevation Foyer |
| 11:10–12:10 PM |
Panel Discussion: Funding Opportunities |
Elevation Ballroom |
| 12:10–5:00 PM |
On Own for Lunch |
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| 4:30–5:00 PM |
Coffee Available |
Elevation Foyer |
| 5:00–6:45 PM |
Interpreting Correlative Datasets |
Elevation Ballroom |
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Janet Iwasa, University of Utah School of Medicine
New Tools for Animating Dynamic Molecular Models |
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Elizabeth Kellogg, St. Jude Children's Research Hospital
From Structure to Function: Integrative Approaches for Understanding Complex Biological Systems |
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Peter Dahlberg, Stanford University
Integration of Advanced Optical Microscopy into FIB-Milling Platforms |
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Jake Johnston †, Columbia University/NYSBC
Short Talk: DisTangle: A Deep Learning Tool for Cryo-ET Filament Semantic and Instance Segmentation |
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
Elevation Ballroom |
| 7:00–8:00 PM |
Social Hour with Dinner |
Forest Ballroom and Lounge |
| 8:00–9:00 PM |
Cash Bar |
Forest Ballroom and Lounge |
| 8:00–9:00 PM |
Entertainment |
Forest Ballroom and Lounge |
