Hormonal Influences on Immunity and Cancer Across the Lifespan (F2)
October 4-8, 2026  | Beaver Run Conference Center, Breckenridge, CO, United States
Suzanne D. Conzen, Amy Moran and James DeGregori
* Session Chair † Invited but not yet accepted | Program current as of December 15, 2025 7 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, October 4, 2026
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Monday, October 5, 2026
4:00–4:10 PM Welcome Remarks
4:10–5:00 PM Keynote Address
  Alberto Mantovani, Humanitas University
Intersection of Inflammation and Cancer
 
5:00–7:00 PM Hormones, Age, Immunity and Cancer Risk
  Quinn Ostrom, Duke University
Talk Title to be Announced
 
  Duygu Ucar, The Jackson Laboratory
Sexual-Dimorphism in Human Immune System Aging
 
  Christy Hagan, University of Kansas Medical Center
Hormone–Immune Crosstalk: How Progesterone Enables Immune Escape in Breast Cancer
 
  Short Talk(s) Chosen from Abstracts
 
Tuesday, October 6, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Sex Differences in Cancer Immunity and Outcomes
  Joseph Unger, Fred Hutchinson Cancer Center
Cancer Treatment Outcomes and Sex Differences: Evaluations Using Clinical Trial Databases
 
  Amy Moran, Oregon Health & Science University
Hormone Receptor Action as Immune Modifiers Affecting IO Outcome
 
  Fabio Conforti, European Institute of Oncology
Sex Differences in the Efficacy of Immunotherapy for Various Cancers, with Immunotherapy being Less Effective in Women than in Men
 
  Michael Angelo †, Stanford University
Talk Title to be Announced
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:00–12:00 PM Panel Discussion 1: Machine Learning and Artificial Intelligence
  * Kendall W. Nettles, The Scripps Research Institute
 
12:00–1:00 PM Poster Setup
12:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Neuroendocrine Immune Regulation of Cancer - the Host, the Cancer Cell and the Microenvironment
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Physiological and Social Stressors: Puberty, Pregnancy, & Menopause
  Pepper Jo Schedin, Oregon Health & Science University
Discovery of Mechanisms by Which Hormonal Changes of the Lifespan Affect Cancer Risk
 
  Suzanne D. Conzen, University of Texas Southwestern Medical Center
Pubertal Social Stressors and the Role of Glucocorticoid Receptor in Mammary Gland Development and Cancer Risk
 
  Elizabeth A. Bonney, University of Vermont
Pregnancy’s Influence on T Cell Regulation
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Wednesday, October 7, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM The Aging Host and the Role of the Microenvironment
  Emi K. Nishimura †, University of Tokyo
Melanocyte Stem Cells (McSCs) and their Niche Coordinately Determine Individual Stem Cell Fate through Depending on Exposome
 
  Joao Passos, Mayo Clinic
How Mitochondria Fuel Inflammation: Implications for Healthy Aging
 
  Curtis J. Henry, University of Colorado Cancer Center
The Epigenetic Landscape of Breast Cancer, Metabolism, and Obesity
 
  Lydia Lynch †, Princeton University
Dietary Fat Influences Anti-Tumor Immunity in Obese Mice
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–12:00 AM Panel Discussion 2: Aging of the Tumor Microenvironment - Who are the Main Players?
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable: Successful Interdisciplinary Science and Learning to Speak another Language
4:30–5:00 PM Coffee Available
5:00–7:00 PM Metabolic and Hormonal Changes during Aging as a Driver of Tumorigenesis
  Ana P. Gomes, Lee Moffitt Cancer Center & Research Institute
Understanding Cancer through the Lens of Old Age
 
  Nima Sharifi, University of Miami
Talk Title to be Announced
 
  Michael Hwang, Genentech
Nuclear Hormone Receptor Signaling and Anti-Tumor Immunity
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Thursday, October 8, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Immune Senescence and Healthspan
  James DeGregori, University of Colorado Denver School of Medicine
Clonal Hematopoiesis and Cancer Prevention
 
  Karin E. de Visser †, Netherlands Cancer Institute
Tumor Driven Reprogramming of the Myelopoiesis
 
  Yash Chhabra, Fox Chase Cancer Center
Beyond the Surface: Decoding Age and Sex Disparity in Melanoma Progression and Therapy Response
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Epigenetics and Cancer Over the Lifespan - Tumor and the Microenvironment
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM The Aging Immune System and the Onset of Disease
  Kendall W. Nettles, The Scripps Research Institute
Using Machine Learning to Model Nuclear Receptor Biology in T Cells and Tissues
 
  David Furman †, Buck Institute for Research on Aging
Measuring Immune Function in Humans and Machine Learning Tools to Better Define the Role of the Immune System in Disease and Longevity
 
  Ben A Youngblood, St. Jude Children's Research Hospital
Translating Epigenetic Mechanisms of T Cell Exhaustion into Durable Tumor Immunity
 
  Alison Ringel, Massachusetts Institute of Technology
Age-Related effects on Anti-Tumor Immunity
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
Friday, October 9, 2026
8:00–11:59 PM Departure