Hormonal Influences on Immunity and Cancer Across the Lifespan (F2)
October 4-8, 2026  | Beaver Run Conference Center, Breckenridge, CO, United States
Suzanne D. Conzen, Amy Moran and James DeGregori
* Session Chair † Invited but not yet accepted | Program current as of November 4, 2025 2 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, October 4, 2026
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Monday, October 5, 2026
4:00–5:00 PM Welcome and Keynote Address
  Alberto Mantovani, Humanitas University
Intersection of Inflammation and Cancer
 
5:00–7:00 PM Hormones, Age, Immunity and Cancer Risk
  Speaker to be Announced
 
  Duygu Ucar †, The Jackson Laboratory
Sexual-Dimorphism in Human Immune System Aging
 
  Juulia Jylhävä †, Karolinska Institute
Large-Scale Genome-Wide Analyses with Proteomics Integration Reveal Novel Loci and Biological Insights into Frailty
 
  Short Talk(s) Chosen from Abstracts
 
Tuesday, October 6, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Sex Differences in Cancer Immunity and Outcomes
  Joseph Unger †, Fred Hutchinson Cancer Center
Cancer Outcomes and Sex Differences- Across the Lifespan
 
  Amy Moran, Oregon Health & Science University
Hormone Receptor Action as Immune Modifiers Affecting IO Outcome
 
  Fabio Conforti †, European Institute of Oncology
Sex Differences in the Efficacy of Immunotherapy for Various Cancers, with Immunotherapy being Less Effective in Women than in Men
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:00–12:00 PM Panel Discussion 1: Machine Learning and Artificial Intelligence
  * Kendall W. Nettles †, The Scripps Research Institute
 
12:00–1:00 PM Poster Setup
12:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Neuroendocrine Immune Regulation of Cancer - the Host, the Cancer Cell and the Microenvironment
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Physiological and Social Stressors: Puberty, Pregnancy, & Menopause
  Pepper Jo Schedin †, Oregon Health & Science University
Discovery of Mechanisms by Which Hormonal Changes of the Lifespan Affect Cancer Risk
 
  Suzanne D. Conzen, University of Texas Southwestern Medical Center
Pubertal Social Stressors and the Role of Glucocorticoid Receptor in Mammary Gland Development and Cancer Risk
 
  Elizabeth A. Bonney, University of Vermont
Pregnancy’s Influence on T Cell Regulation
 
  Weiping Zou †, University of Michigan
B7-H4 as a Previously Unrecognized Onco-Fetal Immune Tolerance Checkpoint Driven by Progesterone Signaling
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Wednesday, October 7, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM The Aging Host and the Role of the Microenvironment
  Speaker to be Announced
 
  Speaker to be Announced
 
  Curtis J. Henry, University of Colorado Cancer Center
The Epigenetic Landscape of Breast Cancer, Metabolism, and Obesity
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–12:00 AM Panel Discussion 2: Aging of the Tumor Microenvironment - Who are the Main Players?
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable: Successful Interdisciplinary Science and Learning to Speak another Language
4:30–5:00 PM Coffee Available
5:00–7:00 PM Metabolic and Hormonal Changes during Aging as a Driver of Tumorigenesis
  Ana P. Gomes, Lee Moffitt Cancer Center & Research Institute
Understanding Cancer through the Lens of Old Age
 
  Speaker to be Announced
 
  Michael Hwang †, Genentech
For the Immune and Hormone Connection, we have a Great Young Scientist in our Translational Medicine
 
  Johan Auwerx †, École Polytechnique Fédérale de Lausanne
Nuclear Receptors, Lifespan, Inflammation, Disease, Founded Several Companies
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Thursday, October 8, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Immune Senescence and Healthspan
  James DeGregori, University of Colorado Denver School of Medicine
Clonal Hematopoiesis and Cancer Prevention
 
  Morgan Levine †, Altos Labs
Aging Epigenetics and Cancer Risk
 
  Speaker to be Announced
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Epigenetics and Cancer Over the Lifespan - Tumor and the Microenvironment
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM The Aging Immune System and the Onset of Disease
  Kendall W. Nettles †, The Scripps Research Institute
Using Machine Learning to Model Nuclear Receptor Biology in T Cells and Tissues
 
  David Furman †, Buck Institute for Research on Aging
Measuring Immune Function in Humans and Machine Learning Tools to Better Define the Role of the Immune System in Disease and Longevity
 
  Ben A Youngblood, St. Jude Children's Research Hospital
Translating Epigenetic Mechanisms of T Cell Exhaustion into Durable Tumor Immunity
 
  Speaker to be Announced
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
Friday, October 9, 2026
8:00–11:59 PM Departure