Biosecurity and Infectious Diseases: Pandemic Threats, Frontline Research, and the Path Forward (F2)
September 20-24, 2027  | Location to be Determined
Melanie M Ott, Olivier Schwartz and Leo Poon
* Session Chair † Invited but not yet accepted | Program current as of September 1, 2026 4 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, September 20, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, September 21, 2027
7:00–8:00 AM Breakfast
8:00–8:10 AM Welcome Remarks (Joint)
8:10–8:40 AM Keynote Session (Joint)
  Raul Andino †, University of California, San Francisco
Virus Evolution and Live-Attenuated Viral Vaccines
 
  Wendy Barclay †, Imperial College London
The Arsenal of Modern Virology: From Viral and Human Genetics to Human Challenge Studies
 
8:40–11:15 AM Spillover Risk, Surveillance and Potential from Animals to Humans (Joint)
  Le Van Tan †, Oxford University Clinical Research Unit
Viral Surveillance: What Probing Nature Teaches Us About Pandemic Preparedness
 
  Michael S. Diamond †, Washington University School of Medicine
Zoonotic Reservoirs, Spillover Mechanisms, and Surveillance of Emerging Positive-Strand RNA Viruses
 
  Cleo Bertelsmeier †, University of Lausanne
Wildlife Trade Drives Animal-to-Human Pathogen Transmission
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:15–1:00 PM Poster Setup
11:25–12:25 PM Panel Discussion 1: Global Risk-Value Framework of Spillover and General Infectious Disease Research
  * Leo Poon, University of Hong Kong
 
  Cleo Bertelsmeier †, University of Lausanne
 
  James W. Black †, OpenAI
 
12:25–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Emerging Pathogens: Discovery, Surveillance, and Preparedness
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM New Frontiers of Pathogen Research
  Melanie M Ott, Gladstone Institutes
From Viral Evolution to Pandemic Preparedness: Safe, High-Throughput Experimental Approaches to Predict Emerging Viral Variants
 
  Olivier Schwartz, Institut Pasteur
Viral Evolution and Immune Escape: Lessons for Next-Generation Therapeutics
 
  Christian Drosten †, Charité - Universitätsmedizin Berlin
Ancient Virus Evolution: Lessons and Responsibilities Today
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Wednesday, September 22, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM AI in Infectious Disease Research (Joint)
  Ethan Jackson †, Microsoft
Project Premonition: Reimagining Pathogen Surveillance with AI, Robotics, and Genomics
 
  Aude Bernheim †, Institut Pasteur
Evolution of Immunity Across Domains of Life
 
  Kathryn Tunyasuvunakool †, DeepMind
From AlphaFold to AI for Scientific Discovery
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable (Joint)
4:30–5:00 PM Coffee Available
5:00–7:00 PM Transparency and Responsible Communication in Infectious Disease Research
  Leo Poon, University of Hong Kong
Open Data in a Pandemic: Building Trust Through Global Pathogen Surveillance
 
  Lalitha Sundaram †, University of Cambridge
Biosecurity and Pandemic Preparedness in a New Age of Infectious Disease Research
 
  Kevin M. Esvelt †, MIT Media Lab
Safeguarding Exponential Biology
 
  Lisa F.P. Ng †, Infectious Diseases Labs, ASTAR
From Discovery to Dialogue: Communicating Infectious Disease Research for Public Trust
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Thursday, September 23, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM From Discovery to Countermeasures
  Jesse D. Bloom †, Fred Hutchinson Cancer Research Center
The Evolutionary Origins of Emerging Viruses: Predicting the Next Spillover
 
  Christian T. Happi †, Redeemer's University
Genomics Against Epidemics: Building African Leadership in Infectious Disease Research
 
  Minkyung Baek †, Seoul National University
Landscape-Scale Navigation Unlocks Antibody CDR Structural Logic for AI-Guided Rescue and Therapeutic Optimization
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
11:10–12:10 PM Panel Discussion 2: Defining Standards, Boundaries, and Opportunities
  * Melanie M Ott, Gladstone Institutes
 
  Michael S. Diamond †, Washington University School of Medicine
 
  Lalitha Sundaram †, University of Cambridge
 
  Lisa McDonald †, Global Health Security Fund,
 
  Herbert 'Skip' W Virgin †, Gates Foundation
 
2:30–4:30 PM Symposia Spotlight 2: Translating Discovery into Preparedness and Public Health
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Sharing Global Risks and Resources
  James W. Black †, OpenAI
Biological Foundation Models: Emerging Capabilities and Biosecurity Risks
 
  Lisa McDonald †, Global Health Security Fund,
Public-Private Models for Globally Aligned Health Security
 
  Herbert 'Skip' W Virgin †, Gates Foundation
Enabling Innovation While Managing Risk: A Global Health Perspective on Infectious Disease Research
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Friday, September 24, 2027
12:00–11:59 PM Departure