Vaccinology During and After COVID-19 (F6)
September 17-20, 2023  | Atlanta Marriott Marquis, Atlanta, GA, United States
Bali Pulendran, Robert A. Seder and Gagandeep Kang
Scholarship Deadline: Jun. 15, 2023 | Abstract Deadline: Jun. 15, 2023 | Early Registration Deadline: Jul. 19, 2023
* Session Chair † Invited but not yet accepted | Program current as of June 22, 2025 5 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, September 17, 2023
4:00–8:00 PM Arrival and Registration International Salon Foyer
6:00–6:15 PM Welcome Remarks International Salon Foyer
6:00–8:00 PM Welcome Mixer International Salon Foyer
  * Bali Pulendran, Stanford University School of Medicine
Session Chair		  
  Barney S. Graham, Morehouse School of Medicine
Vaccine Equity and the Future of Global Health		  
  * Maria Elena Bottazzi, Baylor College of Medicine
Session Chair		  
  * Dan H. Barouch, Beth Israel Deaconess Medical Center
Session Chair		  
  Maria Elena Bottazzi, Baylor College of Medicine
COVID-19 Vaccine Technologies Bolstering the Development of Neglected Tropical Disease Vaccines		  
  Dan H. Barouch, Beth Israel Deaconess Medical Center
Correlates of Protection for COVID-19 Vaccines		  
  Jay K. Kolls, Tulane School of Medicine
Clinical Development of an Intranasal Pneumonia Vaccine that Targets Th17 TRM Cells		  
  Tyler D Gavitt, Duke University School of Medicine
Short Talk: Short Talk: A Trivalent RBD-nanoparticle Vaccine Elicits Protective Immunity against Three Human-pathogenic Coronavirus Species in Mice		  
Monday, September 18, 2023
7:30–8:30 AM Breakfast International Salon 1-3
8:00–8:30 AM Poster Setup International Salon 7-10
8:30–9:30 AM Welcome and Keynote Address International Salon 4-6
  * Jay K. Kolls, Tulane School of Medicine
Session Chair		  
  * Chinnaswamy Jagannath, Houston Methodist Research Institute
Session Chair		  
  Frank Wegmann, Janssen Vaccines & Prevention
Mucosal Boosting Enhances Vaccine Protection Against SARS-CoV-2 in Rhesus Macaques		  
  Chinnaswamy Jagannath, Houston Methodist Research Institute
A Self-adjuvated Vaccine Induces Multiple Pathways of Innate Immunity Protecting Mice against Tuberculosis		  
  Fredrika Hellgren, Karolinska Institutet
Prior SARS-CoV-2 Infection Modulates the Early Inflammatory Response to mRNA Vaccination		  
  Yupeng Feng, Stanford University
Evolution of Antibody Immunity to Subunit COVID-19 Vaccines		  
  Pritesh Desai, Washington University
Intestinal Helminth Infection Impairs Vaccine-induced T Cell Responses and Protection against a SARS-CoV-2 Omicron Variant in Mice		  
  Cuiping (Catherine) Liu, NIH
Genetic Immunization with Self-Assembling SARS-CoV-2 Spike-HBsAg Nanoparticles		  
8:30–7:00 PM Poster Viewing International Salon 7-10
9:30–11:45 AM Vaccine Platforms for COVID-19 and Beyond International Salon 4-6
10:00–10:20 AM Coffee Break International Salon Foyer
  * Pamela J. Bjorkman, California Institute of Technology
Session Chair		  
  Pamela J. Bjorkman, California Institute of Technology
Towards a Vaccine Against Animal Sarbecoviruses and SARS-CoV2 Variants that would not need Updating		  
  Barton F. Haynes, Duke University Medical Center
Strategy for the Development of Pancoronavirus Vaccines: Immunogen Designs and Protective Immune Responses		  
  Ankita Leekha, University of Houston
Short Talk: Short Talk: Ending Transmission: Multi-antigen Intranasal Vaccines Protect against Challenge by Diverse Sarbecoviruses		  
  Harry Kleanthous, SK Biosciences
A Nanoparticle based Pan Coronavirus and Influenza Vaccines		  
11:45–1:00 PM Lunch International Salon 7-10
12:30–2:30 PM Poster Session 1 International Salon 7-10
2:30–4:30 PM Workshop 1: Immune Responses to Vaccination International Salon 4-6
4:30–5:00 PM Coffee Available International Salon Foyer
5:00–7:00 PM Pan Pathogen Vaccines International Salon 4-6
  * Mala K. Maini, University College London
Session Chair		  
  * Donna L. Farber, Columbia University Medical Center
Session Chair		  
  Alessandro Sette, La Jolla Institute for Immunology
Breakthrough Infection Enhances Sars-Cov-2-Specific T Cell Responses and Generates Novel Epitope Specificities		  
  Robert A. Seder, NIAID, National Institutes of Health
T Cell Quality in Memory and Protection		  
  Donna L. Farber, Columbia University Medical Center
Durable Vaccine Immunity in Human Tissues		  
  Mala K. Maini, University College London
T Cell based COVID Protection Before and after the Pandemic		  
  Laura Su, University of Pennsylvania
Pre-Existing Memory in Vaccine Responses		  
Tuesday, September 19, 2023
  Rino Rappuoli, Fondazione Biotecnopolo di Siena
Scientific Director		  
  Maria Elena Bottazzi, Baylor College of Medicine
Associate Dean & Professor		  
  Laura Su, University of Pennsylvania
Assistant Professor & Physician		  
7:30–8:30 AM Breakfast International Salon 1-3
8:30–11:30 AM T-Cell Based Vaccines International Salon 4-6
  * Gagandeep Kang, Bill and Melinda Gates Foundation
Session Chair		  
  Fan Zhou, University of Bergen
Age Related Differences in Kinetics and Magnitude of SARS-CoV-2 and Endemic Human Coronavirus Reactive Antibody Responses After Vaccination and Infection		  
  Lobke Hensen, University Medical Center Utrecht
T Cell Immune Response Induced by Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination in Down Syndrome		  
  Francesco Berlanda Scorza, Gsk Vaccines Institute For Global Health Srl (Gvgh)
A Strategic Model and Industry Collaboration for Sustainable Development of Vaccines against Neglected Diseases		  
  Jerome Nyhalah Dinga, University of Buea
Combating the Loss in Childhood Immunization Gains in Rural Communities and Vaccination of Disabled Persons due to Covid-19: The Approach of Building Relationships and Harnessing Power in the Community		  
  Ramya Madhavan, Christian Medical College
Humoral Immune Response Elicited by Mix-and-Match SARS-CoV-2 Vaccination Strategies in India		  
9:30–9:50 AM Coffee Break International Salon Foyer
  * Shane Crotty, La Jolla Institute for Immunology
Session Chair		  
  * Rafi Ahmed, Emory University School of Medicine
Session Chair		  
  Rafi Ahmed, Emory University School of Medicine
Durability of Immune Responses to Vaccination and Infection		  
  Shane Crotty, La Jolla Institute for Immunology
Immune Memory to Infection and COVID-19 Vaccination		  
  Grace Hendricks, University of Washington
Short Talk: Computationally Designed mRNA-launched Nanoparticle Vaccines		  
  Vamsee Mallajosyula, Stanford University
Short Talk: Short Talk: Broadening T Cell Help by Antigen Crosslinking as a Universal Vaccine Platform against Rapidly Evolving Pathogenic Viruses		  
  Sandhya Bangaru, The Scripps Research Institute
Short Talk: Short Talk: Structural Evaluation of Serum Polyclonal Antibody Responses to mRNA-1273 and NVX-CoV2373 Vaccines		  
11:30–1:00 PM Poster Setup International Salon 7-10
11:30–5:00 PM On Own for Lunch
1:00–2:00 PM Career Roundtable International Salon 4-6
1:00–10:00 PM Poster Viewing International Salon 7-10
3:00–4:30 PM Workshop 2: Equity in Vaccine Responses International Salon 4-6
4:30–5:00 PM Coffee Available International Salon Foyer
5:00–7:00 PM B Cell and Antibody Responses To Vaccination International Salon 4-6
7:00–8:15 PM Social Hour with Lite Bites International Salon 7-10
7:30–10:00 PM Poster Session 2 International Salon 7-10
  * Galit Alter, Moderna, Inc.
Session Chair		  
  * Karin Loré, Karolinska Institutet
Session Chair		  
  Bali Pulendran, Stanford University School of Medicine
Innate Immune Predictors and Mechanisms of Vaccination		  
  Galit Alter, Moderna, Inc.
Structural and Functional Determinants of Antibody Responses to Vaccination and Infection		  
  Karin Loré, Karolinska Institutet
Immune Responses Elicited by mRNA Vaccines Compared to Traditional Vaccine Platforms		  
  Mark M. Davis, Stanford University School of Medicine, Howard Hughes
Measuring Vaccine Immunity in a Dish		  
  Paola A Lopez Zapana, MIT
Short Talk: Short Talk: Placental Transfer and Durability of Maternal COVID-19 Vaccine-induced Antibodies in Infants through 6 Months of Age		  
  Katerina Roznik, Johns Hopkins University
Short Talk: Short Talk: Hepatitis C Virus Vaccine Immunogenicity in People who Inject Drugs: Investigating the Impact of Opioids on Dysregulated Neutrophil and T Cell Function		  
Wednesday, September 20, 2023
7:30–8:30 AM Breakfast International Salon 1-3
  * Bali Pulendran, Stanford University School of Medicine
Session Chair		  
  * Robert A. Seder, NIAID, National Institutes of Health
Session Chair		  
  Slim Fourati, Northwestern University
Pan-vaccine Analysis Reveals Innate Immune Endotypes Predictive of Antibody Responses to Vaccination		  
  Thomas Hagan, Cincinnati Children's Hospital
Transcriptional Atlas of the Human Immune Response to 13 Vaccines		  
  Hyun Jik Kim, Seoul National University College of Medicine
Distinct Interferon-related Innate Immune Signatures in the Nasopharynx of COVID-19 Patients Depending on Disease Severity or Vaccine History		  
  Vicki Stylianou, Westmead Institute for Medical Research
Adjuvant AS01 Activates Subcapsular Sinus Macrophages and Dendritic Cells in Human Lymph Node Explants		  
  Sanya Thomas, Boston Children's Hospital/Harvard Medical School
Human in vitro Modeling Characterizes Mechanism of Action of Adjuvantation Systems Defining Scalable and Affordable Precision Vaccine Formulations for Early Childhood		  
  Antonella Prisco, National Research Council
Evaluation of COVID-19 Vaccination Protocols in an Agent-based Immune Simulation Platform		  
8:30–11:30 AM Measuring and Predicting Immunity to Vaccination International Salon 4-6
9:30–9:50 AM Coffee Break International Salon Foyer
  * Rino Rappuoli, Fondazione Biotecnopolo di Siena
Session Chair		  
  Gagandeep Kang, Bill and Melinda Gates Foundation
Enhancing Vaccine Equity Before and After COVID-19		  
  Rino Rappuoli, Fondazione Biotecnopolo di Siena
Preparing for the Next Pandemic		  
  Nadia Rachel Cohen, CEPI
The CEPI Portfolio and Ecosystem Supports Development of Coronavirus Vaccines		  
11:30–5:00 PM On Own for Lunch
2:30–4:30 PM Workshop 3: Measuring and Predicting Immunity to Vaccination and Infection International Salon 4-6
4:30–5:00 PM Coffee Available International Salon Foyer
5:00–6:45 PM Vaccinology in the Post-COVID Era International Salon 4-6
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) International Salon 4-6
7:00–8:00 PM Social Hour with Lite Bites International Salon 7-10
8:00–9:00 PM Cash Bar International Salon 7-10
Thursday, September 21, 2023
7:00–11:59 PM Departure