Neurodevelopmental Disorders: Risk Factors and Molecular Mechanisms (H9)
January 1-4, 2026
| Location to be Determined
Maria Carolina Marchetto and Patricia C. B. Beltrão-Braga
Thursday, January 1, 2026
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–9:00 AM |
Welcome and Keynote Address |
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Daniel H. Geschwind †, University of California, Los Angeles
Characterization of Gene Regulatory Elements in Human Fetal Cortical Development: Enhancing Our Understanding of Neurodevelopmental Disorders and Evolution |
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| 9:00–11:15 AM |
Genomic Risk Factors in Neurodevelopmental Disorders |
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Stephen W. Scherer †, Hospital for Sick Children, University of Toronto
Environmental Exposures Associated with Elevated Risk for Autism Spectrum Disorder May Augment the Burden of Deleterious de novo Mutations Among Probands |
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Michael F. Wells †, University of California, Los Angeles
Using 'Village-in-a-Dish' Approach to Study the Impact of Human Genetic Variation on Phenotypic Diversity |
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Kristen J. Brennand †, Yale School of Medicine
Using Stem Cells to Explore the Genetics Underlying Schizophrenia |
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Short Talk(s) Chosen from Abstracts
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|
| 9:30–9:50 AM |
Coffee Break |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Workshop: New Therapeutical Approaches for Modeling Neurodevelopmental Disorders |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Mechanistic Insights on Neurodevelopmental Disorders |
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Kasper Lage †, Broad Institute of MIT and Harvard
Protein Interaction Studies in Human Induced Neurons Indicate Convergent Biology Underlying Autism Spectrum Disorders |
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Renata Santos †, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266
Deficient LEF1 Expression is Associated with Lithium Resistance and Hyperexcitability in Neurons Derived from Bipolar Disorder Patients |
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Berit Elissa Powers †, Ionis Pharmaceuticals, Inc.
Screening Small Molecules in ES and iPS-Derived Motor Neurons to Identify Therapeutic Compounds for SMA |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Lite Bites |
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Saturday, January 3, 2026
| 8:00–11:00 AM |
3-D Models to Investigate Neurodevelopmental Disorders |
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Giorgia Quadrato †, University of Southern California, USC Stem Cell
Upgrading the Physiological Relevance of Human Brain Organoids |
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Maria Carolina Marchetto, University of California, San Diego
Impact of AUTS2 Deficiency on the Differentiation of Human Neurons |
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Madeline Lancaster †, Medical Research Council Laboratory of Molecular Biology
Human Brain Development Using Cerebral Organoids |
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Jin-Yuan Wang †, STEMCELL Technologies Inc.
Using Human Pluripotent Stem Cell-Derived Neural Organoids for Disease Modeling |
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| |
Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–1:00 PM |
Poster Setup |
|
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
|
| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Accessing Neuronal Activity in Human Models for Neurodevelopmental Disorders |
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Krishnan Padmanabhan †, University of Rochester School of Medicine
Network Size Affects the Complexity of Activity in Human iPSC-Derived Neuronal Populations |
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Anne G. Bang †, Sanford Burnham Prebys Medical Discovery Institute
Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks |
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Marie Obien †, MaxWell Biosystems
Advanced Functional Characterization of iPSC-Derived in vitro Models in Disease Modelling and Artificial Intelligence |
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Short Talk(s) Chosen from Abstracts
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|
| 7:00–8:00 PM |
Social Hour with Lite Bites |
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| 8:00–11:00 AM |
Environmental Risk Factors in Neurodevelopmental Disorders |
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Anca M. Pasca †, Stanford University
Stem Cell Models for Neonatal Hypoxia |
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Lena Smirnova †, Johns Hopkins University
Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres |
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Lorenz Studer †, Memorial Sloan Kettering Cancer Center
An Epigenetic Barrier Sets the Timing of Human Neuronal Maturation |
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Cathy Barr †, University of Toronto
Neurobiology of Reading Disabilities and Comorbid Disorders: Genetic findings and Stem Cell Models |
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Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Viral Infections and Neurodevelopmental Disorders Outcomes |
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Patricia C. B. Beltrão-Braga, University of São Paulo
Viral Infections and Neurodevelopmental Disorders Outcomes |
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Raphael Gaudin †, CNRS
Brain Exposure to SARS-CoV-2 Virions Perturbs Synaptic Homeostasis |
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Karin Nielsen †, University of California, Los Angeles
Neurodevelopmental Delay in Children Exposed to Maternal SARS-CoV-2 In-Utero |
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Short Talk(s) Chosen from Abstracts
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|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Lite Bites |
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| 8:00–11:00 PM |
Entertainment |
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