From Systems Immunology to Immunoengineering (J1)
January 11-14, 2026
| Fairmont Hotel Vancouver, Vancouver, BC, Canada
Alexander Hoffmann, Eicke Latz and Stacey D Finley
Scholarship Deadline: Oct. 10, 2025 | Abstract Deadline: Dec. 19, 2025 | Early Registration Deadline: Nov. 13, 2025
| 4:00–8:00 PM |
Registration |
British Columbia Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
British Columbia Foyer |
| 7:30–8:30 AM |
Breakfast |
Pacific Ballroom |
| 8:30–8:40 AM |
Welcome Remarks (Joint) |
Columbia Ballroom |
| 8:40–10:00 AM |
Keynote Session (Joint) |
Columbia Ballroom |
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* Dequina Angelina Nicholas, University of California, Irvine
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* Alexander Hoffmann, University of California, Los Angeles
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Marcia C. Haigis, Harvard Medical School
Investigating the Role of Metabolites in Immune Cells across Scales: Spanning Molecules and Cells to the Host |
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Christina S. Leslie, Memorial Sloan-Kettering Cancer Center
T Cell Mediated Immunity; Chromatin States; Comp Bio |
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| 10:00–10:20 AM |
Coffee Break |
British Columbia Foyer |
| 10:20–10:25 AM |
Award Recipient Acknowledgement |
Columbia Ballroom |
| 10:25–12:25 PM |
Inside the Cell's Kitchen: Mastering the Art of Nutrient Signaling (Joint) |
Columbia Ballroom |
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* Adam P Williamson, Bryn Mawr College
Session Chair |
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Dequina Angelina Nicholas, University of California, Irvine
Same Cells, Different Menus: Metabolic Pathways that Divide |
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Eicke Latz, German Rheumatology Research Center (DRFZ)
Myeloid Cell Signaling/Immunometabolism/Personalized Medicine |
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Steven J. Bensinger, University of California, Los Angeles
Regulation of Immune Cell Function by Lipid Metabolism |
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Joel Babdor, University of Pennsylvania
Short Talk: Microbiome Mediators Control the Immune Tone in Health and Disease |
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* Ekaterina Vinogradova, Rockefeller University
Short Talk: Chemical Proteomic Approaches to Study and Modulate T Cell Function |
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| 12:25–1:00 PM |
Poster Setup |
Vancouver Island Room |
| 12:25–2:30 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Vancouver Island Room |
| 2:30–4:30 PM |
Symposia Spotlight 1: Multi-Scale Communication and Coordination |
British Ballroom |
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* Benedict Seddon, University College London
Session Chair |
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* Leyuan Ma, Children's Hospital Of Philadelphia/University of Pennsylvania
Session Chair |
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Prabal Chhibbar, University of Pittsburgh
Discovering Viral Evolutionary Constraints Essential For Hijacking Host Cellular Machinery To Design Broadly Neutralizing Immunotherapies |
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Tyler T Dao, MIT
Robust T Cell Activation Kills Tumors Regardless of T Cell Specificity |
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Erika M. Palmieri, National Cancer Institute (NCI) / NIH
Metabolic Reprogramming of Tumor Microenvironment by Nitric Oxide |
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Jacob Parres-Gold, Caltech
Competitive Protein Dimerization Enables Cell-type-specific Signal Integration |
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Antonella Prisco, Institute of Genetics and Biophysics
Modeling the Magnitude and Persistence of the Antibody Response Through the Contributions of Different Subsets of Antibody-Secreting Cells |
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Taehyun Kim, University of British Columbia
A Microbiome-Derived Metabolite Suppresses Neutrophilic Airway Inflammation in Type 2-Low Asthma |
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Heekyong Rachel Bae, Kyungpook National University
Chronic Interferon-γ Signaling Bridges Obesity to Female-Predominant Autoimmune Diseases through M1-Linked Type I IFN Amplification |
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| 4:30–5:00 PM |
Coffee Available |
British Columbia Foyer |
| 5:00–6:45 PM |
Circuits to Regulate Immune Cell Function |
British Ballroom |
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* Jinhong Wie, The Catholic University of Korea. College of Medicine
Session Chair |
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Catera L Wilder, University of California, San Francisco
The Integration of Molecular Mechanisms Controlling Signaling Specificity |
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Jamie Spangler, Johns Hopkins University
Engineering Cytokine/Antibody Fusion Proteins for Targeted Immunotherapy |
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Ellen V. Rothenberg, California Institute of Technology
Regulatory Networks for T Cell Development |
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Jishnu Das, University of Pittsburgh
Short Talk: A Unified Network Systems Approach Uncovers a Core Novel Program Underlying T Follicular Helper Cell Differentiation |
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| 6:45–8:00 PM |
Social Hour with Dinner |
Pacific Ballroom |
| 7:30–10:00 PM |
Poster Session 1 |
Vancouver Island Room |
Tuesday, January 13, 2026
| 7:30–8:30 AM |
Breakfast |
Pacific Ballroom |
| 8:30–11:30 AM |
Immune Cell Coordination in Tissues |
British Ballroom |
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* Stacey D Finley, University of Southern California
Session Chair |
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Soumen Basak, National Institute of Immunology
Crosstalk between Signaling Pathways Calibrates Immunoregulatory Dendritic Cell Functions in the Intestine |
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Elsje Pienaar, Purdue University
Multi-Scale Modeling of Host Immune, Pathogen and Drug Dynamics |
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Musa M. Mhlanga, Radboud Institute for Molecular Life Sciences
Epigenetics at the Apex of Vaccination and Senescence |
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Benedict Seddon, University College London
Short Talk: Ontogeny of Foxp3+ Regulatory T cells in Health and Malignant Disease |
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Fangwen Zhao, Center for Molecular Medicine
Short Talk: Integrative Chromatin Accessibility Atlas of Rare Monogenic Immunodeficiencies Reveals Shared and Distinct Dysregulation of Immune Cell Identity |
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Michael Raddatz, UCLA
Short Talk: The Genetic Architecture of Cellular Inflammation in Metabolic Syndrome |
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Xin Liu, Tsinghua University
Short Talk: Tissue-Patrolling GZMK⁺ CD8⁺ T Cells Fuel Recurrence of Airway Inflammatory Diseases |
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| 9:30–9:50 AM |
Coffee Break |
British Columbia Foyer |
| 11:30–1:00 PM |
Poster Setup |
Vancouver Island Room |
| 11:30–2:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Vancouver Island Room |
| 2:00–3:00 PM |
Panel Discussion 1: How to Measure Immune Health |
British Ballroom |
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* Felix Meissner, University Hospital Bonn
Panel Moderator |
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* Musa M. Mhlanga, Radboud Institute for Molecular Life Sciences
Panel Moderator |
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Leif S Ludwig, Berlin Institute of Health and Max Delbrück Center for Molecular Medicine
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Fan Liu, Leibniz-Forschungsinstitut für Molekulare Pharmakologie
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Eicke Latz, German Rheumatology Research Center (DRFZ)
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Alexander Hoffmann, University of California, Los Angeles
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| 3:15–4:30 PM |
Career Roundtable (Joint) |
Columbia Ballroom |
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Fan Liu, Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Group Leader & Professor |
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Rhiannon Macrae, Broad Institute
Scientific Advisor |
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Kelly Moynihan, Curie.Bio
VP, CSO Partner Team |
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Ernesto Andrianantoandro, Cell Press
Scientific Editor |
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| 4:30–5:00 PM |
Coffee Available |
British Columbia Foyer |
| 5:00–6:45 PM |
Dynamic Control of Immunity |
British Ballroom |
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* Eicke Latz, German Rheumatology Research Center (DRFZ)
Session Chair |
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Nicolas Chevrier, University of Chicago
Mechanisms of Combinatorial Sensing in Innate Immunity |
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Alexander Hoffmann, University of California, Los Angeles
Modeling Antibody Responses |
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Edward Botchwey, Georgia Tech & Emory University
Bio-Materials Controlling Immune Cell Function |
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Leyuan Ma, Children's Hospital Of Philadelphia/University of Pennsylvania
Short Talk: Early Bystander Effect of Vaccine Boosting of CAR T Cells Reinvigorates Endogenous anti-Tumor T Cell Immunity to Regress Pancreatic Cancer |
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| 6:45–7:45 PM |
Social Hour with Dinner |
Pacific Ballroom |
| 7:30–10:00 PM |
Poster Session 2 |
Vancouver Island Room |
Wednesday, January 14, 2026
| 7:30–8:30 AM |
Breakfast |
Pacific Ballroom |
| 8:30–11:30 AM |
Technology Driving Immune Research |
British Ballroom |
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* Alexander Hoffmann, University of California, Los Angeles
Session Chair |
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Felix Meissner, University Hospital Bonn
Systems Proteomics, Dissecting Immune Language by Secretomics |
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Fan Liu, Leibniz-Forschungsinstitut für Molekulare Pharmakologie
Using Cross-Linking Mass Spectrometry to Decode Immune Signaling |
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Jenny Jiang, University of Pennsylvania
Immune Engineering, T Cell Receptor |
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Nathaniel Robichaud, Nomic Bio
Short Talk: Identification and Toxicity Profiling of Immunomodulatory Compounds by High-throughput Proteomics |
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Suehyun Cho, Max Planck School Matter to Life
Short Talk: Recording Host-Pathogen Interactions with Salmonella enterica serovar Typhimurium to Trace Long-Term Immune Consequences of Infection |
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Amanda C Hornick, MIT
Short Talk: Interrogating Antiviral Antibody Responses with Multiplexed, High-Throughput Serum Assays |
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Paula P Coelho, Genentech
Short Talk: Systematic Integrated Characterization of Macrophage Plasticity from Molecular Profiles to Cell Images |
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| 9:30–9:50 AM |
Coffee Break |
British Columbia Foyer |
| 11:30–1:45 PM |
On Own for Lunch |
|
| 1:45–3:15 PM |
Symposia Spotlight 2: Dynamics and Heterogeneity |
British Ballroom |
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Adam P Williamson, Bryn Mawr College
Protective Clearance in Health and Disease: An Integrated Approach to Understand and Engineer Phagocyte Biology |
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Helen Huang, UCLA
Temporal Proof-reading for B-cell Selection |
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Ziwei Tian, University of Colorado Denver, Anschutz Medical Campus
Sparse Time Series Chain Graphical Model Dissects the Sequential Humoral–Cellular Immune Dynamics in IV-BCG Vaccinated NHPs against Tuberculosis |
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Michihiro Nakamura, Yamaguchi University Graduate School of Medicine
Heterogeneous Uptake Dynamics Uncover Macrophage-Specificity in the Immune System |
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Joshua A McKeever, University of Chicago
Vitamin D Receptor Modulates NF-κB Bandwidth to Promote Transcriptional Diversity across Thymic Epithelia for Immune Tolerance |
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Riley Mullins, Washington University School of Medicine
Scalable Transcription Factor Mapping Uncovers the Regulatory Dynamics of Natural and Synthetic Transcription Factors in Human T Cell States |
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| 3:30–4:30 PM |
Panel Discussion 2: Immunology in the Age of AI |
British Ballroom |
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Chuangqi Wang, University of Colorado, Anschutz Medical Campus
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| 4:30–5:00 PM |
Coffee Available |
British Columbia Foyer |
| 5:00–6:00 PM |
Systems Metabolism in Health and Disease (Joint) |
Columbia Ballroom |
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* Benjamin Y Winer, NYU Langone
Session Chair |
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* Erika M. Palmieri, National Cancer Institute (NCI) / NIH
Session Chair |
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Leif S Ludwig, Berlin Institute of Health and Max Delbrück Center for Molecular Medicine
Human Immunity through the Lens of Mitochondrial Genetics |
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Stacey D Finley, University of Southern California
Signaling and Metabolic States in Immunotherapy |
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| 6:00–6:45 PM |
Closing Keynote Address (Joint) |
Columbia Ballroom |
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* Susan M Kaech, Allen Institute
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* Alexander Hoffmann, University of California, Los Angeles
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Jeffrey C Rathmell, University of Chicago
Immunometabolism in Health and Disease |
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Joint) |
Columbia Ballroom |
| 7:00–8:00 PM |
Social Hour with Dinner |
Pacific Ballroom |
| 8:00–9:00 PM |
Entertainment |
British Ballroom |
Thursday, January 15, 2026
