Innate Immunity: Molecular Mechanisms, Diseases & Therapeutics (J1)
January 11-14, 2027  | Fairmont Banff Springs, Banff, AB, Canada
Lingyin Li, Carina Cristina de Oliveira Mann and Michael Crackower
Scholarship Deadline: Sep. 16, 2026 | Abstract Deadline: Dec. 22, 2026 | Early Registration Deadline: Nov. 13, 2026
* Session Chair † Invited but not yet accepted | Program current as of August 5, 2026 11 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, January 11, 2027
4:00–8:00 PM Registration Van Horne Foyer
6:00–8:00 PM Welcome Mixer Van Horne Foyer
Tuesday, January 12, 2027
7:00–8:00 AM Breakfast President's Hall
8:00–8:10 AM Welcome Remarks (Joint) Van Horne A/B
8:10–9:00 AM Keynote Address (Joint) Van Horne A/B
  Catherine J Wu, Dana-Farber Cancer Institute
Personalizing Medicine through Cancer Vaccines
 
9:00–11:00 AM T Cells and Innate Allies: Partners in Vaccination (Joint) Van Horne A/B
  Robert A. Seder, NIAID, National Institutes of Health
Vax-Innate
 
  Peter DeMuth, Elicio Therapeutics
Targeting mKRAS Immunotherapy to the Lymph Nodes to Promote Anti-Tumor Immunity
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break Van Horne Foyer
11:10–12:10 PM Meet the Editors Van Horne A/B
12:10–1:00 PM Poster Setup Van Horne C
12:10–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Van Horne C
2:30–4:30 PM Symposia Spotlight 1 Van Horne B
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available Van Horne Foyer
5:00–7:00 PM dsDNA Sensing Van Horne B
  Zhijian James Chen, University of Texas Southwestern Medical Center
cGAS-STING Signaling in Aging
 
  Lingyin Li, Stanford University and Arc Institute
Extracellular cGAMP, the Immunotransmitter that Bridges Innate and Adaptive Immunity
 
  Daniel B. Stetson, University of Washington
How STING Activation Kill Cells
 
  Li Gan, Weill Cornell Medicine
The Role of cGAS/STING in Neurodegeneration
 
7:00–8:00 PM Social Hour with Dinner President's Hall
7:30–10:00 PM Poster Session 1 Van Horne C
Wednesday, January 13, 2027
7:00–8:00 AM Breakfast President's Hall
8:00–11:00 AM ssDNA and RNA Sensing Van Horne B
  Hao Wu, Harvard Medical School, Boston Children's Hospital
Mitochondrial GSDMD
 
  Carina Cristina de Oliveira Mann, Technical University of Munich
Regulation of Nucleic Acid Receptors
 
  Russell E Vance, University of California, Berkeley
Effector-Triggered Immune Detection of Pathogens
 
  Benjamin Morehouse, University of California, Irvine
Evolutionary Conservation of Cyclic Dinucleotide Recognition in Immunity
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break Van Horne Foyer
11:10–12:10 PM Panel Discussion 1: Mouse Human Differences from Pathways to Molecules to Atomic Level Details Van Horne B
12:10–1:00 PM Poster Setup Van Horne C
12:10–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Van Horne C
2:00–3:00 PM Career Roundtable (Joint) Van Horne B
4:30–5:00 PM Coffee Available Van Horne Foyer
5:00–7:00 PM Innate Signals in T Cells (Joint) Van Horne A/B
  Eduardo Davila, University of Colorado
Rewiring T Cell Fate to Increase Anti-tumor Activity and Persistence While Reducing Exhaustion Resistance
 
  Nicolas Manel, Institut Curie
Activation of Intracellular Innate Immune Sensors
 
  Jelena Bezbradica Mirkovic, University of Oxford
Cytosolic Innate Sensing and Lytic Cell Death in Autoinflammation
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner President's Hall
7:30–10:00 PM Poster Session 2 Van Horne C
Thursday, January 14, 2027
7:00–8:00 AM Breakfast President's Hall
8:00–11:00 AM Innate Immunity in Cardiovascular/Metabolic/Autoimmune Diseases Van Horne B
  Min Ae Lee-Kirsch, Technische Universität Dresden
TLR Signaling in Interferonopathy
 
  Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital
Targeting Innate Immune Cell Death, PANoptosis, in Disease
 
  Rayk Behrendt, University of Bonn
Talk Title to be Announced
 
  Michael Crackower, Ventus Therapeutics
Targeting cGAS in Rheumatology and Beyond
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break Van Horne Foyer
11:10–12:10 PM Panel Discussion 2: Drug Development Challenges and VC Takes Van Horne B
12:10–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2 Van Horne B
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available Van Horne Foyer
5:00–6:00 PM Innate Immunity in Neuroinflammation Van Horne B
  Michael T Heneka, University of Luxembourg
The Role of NLRP3 in Microglial Phagocytosis in Alzheimer's Disease
 
  Marina Romero-Ramos, Aarhus University
The Role of the Immune System in Parkinson's Disease
 
6:00–6:50 PM Closing Keynote Address Van Horne B
  Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne
cGAS-STING Pathway in Innate Immunity: Molecular Mechanisms and Therapeutic Implications
 
6:50–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Van Horne B
7:00–8:00 PM Social Hour with Dinner President's Hall
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Friday, January 15, 2027
12:00–11:59 PM Departure