Innate immunity: Molecular mechanisms, Diseases & Therapeutics  (J1)
      
      
      
      
      
      January 11-14, 2027
       | Fairmont Banff Springs, Banff, AB, Canada
      
      
      
         
          Lingyin Li, Carina Cristina de Oliveira Mann and Michael Crackower
        
            
      
      
      
          
      
   
            
     
          
    
      
      
        
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 4:00–8:00 PM | 
            Registration | 
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            | 6:00–8:00 PM | 
            Welcome Mixer | 
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            Tuesday, January 12, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–9:00 AM | 
            Welcome and Keynote Address (Joint) | 
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            |   | 
            Catherine J Wu †, Dana-Farber Cancer Institute Personalizing Medicine through Cancer Vaccines | 
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            | 9:00–11:15 AM | 
            T Cells and Innate Allies: Partners in Vaccination (Joint) | 
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            Robert A. Seder, NIAID, National Institutes of Health Vax-Innate | 
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            Christopher Haqq †, Elicio Therapeutics Lymph Node-Targeting Amphiphile Technology for Next-Generation Vaccines | 
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            Short Talk(s) Chosen from Abstracts
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            | 9:30–9:50 AM | 
            Coffee Break | 
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            | 11:15–1:00 PM | 
            Poster Setup | 
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            | 11:15–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–10:00 PM | 
            Poster Viewing | 
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            | 2:30–4:30 PM | 
            Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions | 
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            Short Talks Chosen from Abstracts
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–7:00 PM | 
            dsDNA Sensing | 
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            |   | 
            Zhijian James Chen †, University of Texas Southwestern Medical Center cGAS-STING Signaling in Aging | 
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            |   | 
            Daniel B. Stetson, University of Washington How STING Activation Kill Cells | 
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            |   | 
            Andrea Ablasser †, Ecole Polytechnique Fédérale de Lausanne cGAS-STING Pathway in Innate Immunity: Molecular Mechanisms and Therapeutic Implications | 
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            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            Wednesday, January 13, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–11:00 AM | 
            Innate Signals in T Cells (Joint) | 
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            |   | 
            Michael B. Brenner †, Harvard Medical School The Role of GZMK+ T-Cells in Inflammatory Disease | 
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            |   | 
            Hong-Bing Shu †, Wuhan University Two Decades of STING Research | 
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            |   | 
            Lingyin Li, Stanford University and Arc Institute Extracellular cGAMP, the Immunotransmitter that Bridges Innate and Adaptive Immunity | 
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            Short Talk(s) Chosen from Abstracts
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            | 9:00–9:20 AM | 
            Coffee Break | 
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            | 11:00–12:00 PM | 
            Panel Discussion 1: Mouse Human Differences from Pathways to Molecules to Atomic Level Details | 
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            | 11:00–1:00 PM | 
            Poster Setup | 
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            | 11:00–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–10:00 PM | 
            Poster Viewing | 
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            | 1:30–2:45 PM | 
            Career Roundtable (Joint) | 
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–7:00 PM | 
            ssDNA and RNA Sensing | 
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            |   | 
            Hao Wu, Harvard Medical School, Boston Children's Hospital Mitochondrial GSDMD | 
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            Carina Cristina de Oliveira Mann, Technical University of Munich Regulation of Nucleic Acid Receptors | 
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            |   | 
            Russell E Vance, University of California, Berkeley Effector-Triggered Immune Detection of Pathogens | 
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            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            Thursday, January 14, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–11:00 AM | 
            Innate Immunity in Cardiovascular/Metabolic/Autoimmune Diseases | 
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            |   | 
            Min Ae Lee-Kirsch, Technische Universität Dresden TLR Signaling in Interferonopathy | 
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            |   | 
            Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital Targeting Innate Immune Cell Death, PANoptosis, in Disease | 
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            Garron Thomas Dodd, University of Melbourne Pathogenic Hypothalamic Extracellular Matrix Promotes Metabolic Disease | 
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            Michael Crackower, Ventus Therapeutics The Development of Non-Canonical Inflammasome Inhibitors for the Treatment of Inflammatory Disease | 
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            Short Talk(s) Chosen from Abstracts
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            | 9:00–9:20 AM | 
            Coffee Break | 
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            | 11:00–12:00 PM | 
            Panel Discussion 2: Drug Development Challenges and VC Takes | 
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            | 12:00–5:00 PM | 
            On Own for Lunch | 
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            | 2:30–4:30 PM | 
            Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions | 
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            |   | 
            Short Talks Chosen from Abstracts
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–6:45 PM | 
            Innate Immunity in Neuroinflammation | 
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            |   | 
            Michael T. Heneka, University of Luxembourg The Role of NLRP3 in Microglial Phagocytosis in Alzheimer's Disease | 
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            Marina Romero-Ramos †, Aarhus University The Role of the Immune System in Parkinson's Disease | 
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            |   | 
            Li Gan, Weill Cornell Medicine The Role of cGAS/STING in Neurodegeneration | 
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            Short Talk(s) Chosen from Abstracts
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            | 6:45–7:00 PM | 
            Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | 
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            | 8:00–11:00 PM | 
            Entertainment | 
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