Immunometabolism Across Scales: From Cells to Systems to Healthspan (J2)
January 11-14, 2026
| Fairmont Hotel Vancouver, Vancouver, BC, Canada
Susan M Kaech, Vishwa Deep Dixit and Dequina Angelina Nicholas
Scholarship Deadline: Oct. 10, 2025 | Abstract Deadline: Dec. 19, 2025 | Early Registration Deadline: Nov. 13, 2025
| 4:00–8:00 PM |
Registration |
British Columbia Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
British Columbia Foyer |
| 7:30–8:30 AM |
Breakfast |
Vancouver Island Room |
| 8:30–8:40 AM |
Welcome Remarks (Joint) |
British / Columbia Ballroom |
| 8:40–10:00 AM |
Keynote Address (Joint) |
British / Columbia Ballroom |
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Marcia C. Haigis, Harvard Medical School
Investigating the Role of Metabolites in Immune Cells across Scales: Spanning Molecules and Cells to the Host |
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Christina S. Leslie, Memorial Sloan-Kettering Cancer Center
T Cell Mediated Immunity; Chromatin States; Comp Bio |
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| 10:00–10:20 AM |
Coffee Break |
British Columbia Foyer |
| 10:20–10:25 AM |
Award Recipient Acknowledgement |
British / Columbia Ballroom |
| 10:25–12:25 PM |
Inside the Cell's Kitchen: Mastering the Art of Nutrient Signaling (Joint) |
British / Columbia Ballroom |
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Dequina Angelina Nicholas, University of California, Irvine
Metabolite Control of Immune Cell Specificity |
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Eicke Latz, University of Bonn
Myeloid Cell Signaling/Immunometabolism/Personalized Medicine |
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Steven J. Bensinger, University of California, Los Angeles
Regulation of Immune Cell Function by Lipid Metabolism |
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Greg M Delgoffe, University of Pittsburgh
Short Talk: Postprandial Alterations to Systemic Metabolism Durably Enhance T Cell Immunity |
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Joel Babdor, University of Pennsylvania
Short Talk: Microbiome Mediators Control the Immune Tone in Health and Disease |
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| 12:25–1:00 PM |
Poster Setup |
British / Columbia Ballroom |
| 12:25–2:30 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
British / Columbia Ballroom |
| 2:30–4:30 PM |
Symposia Spotlight 1 |
Columbia Ballroom |
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Hannah Bumgarner, University of Pittsburgh
When Feast is just as bad as Famine: Hyperglycemic Cell Culture Drives T Cell Dysfunction |
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Chih-Hao Chang, The Jackson Laboratory
Mitochondrial Pyruvate Oxidation Licenses RUNX3-Driven Tim-3 via p300-Dependent Acetylation to Limit CTL Function |
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Yusuke Endo, KAZUSA DNA Research Institute
The Novel Function of Lipid Flux on RORγt-mediated Th17 Cell Pathogenicity |
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SeongJun (James) Han, Harvard University
Metabolic Reprogramming of CD8+ T Cells with Aging Impairs Anti-Tumor Immunity |
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Dustin Hancks, University of Texas Southwestern Medical Center
Mitochondrial ETC Activity Licenses Temporal Progression of Immune States at the Proteome Level |
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Injae Hwang, Perelman School of Medicine, University of Pennsylvania
Unraveling the Switchable Roles of Ketone Body Metabolism of Mesenchymal Stromal Cells in Regulating Adipose Tissue Inflammation and Insulin Resistance |
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Ramiah D Jacks, The Ohio State University
Rapid Adipose Tissue Expansion Triggers Proliferation of Memory Adipose Tissue T cells and Accumulation of Novel “T helper 2 (Th2) Regulatory” Cells |
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Ichiro Katahira, Universitätsklinikum Düsseldorf
Controlling Mitochondrial Membrane Architecture Via MIC60 Determines Viral Replication To Promote Anti-viral Immunity |
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| 4:30–5:00 PM |
Coffee Available |
British Columbia Foyer |
| 5:00–7:00 PM |
Immune Adaptation to Tissue Metabolic Ecosystems |
Columbia Ballroom |
| |
Russell G. Jones, Van Andel Research Institute
Nutrient Preference in Control of Adaptive Immune Responses |
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Cholsoon Jang, University of California, Irvine
Talk Title to be Announced |
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Lydia Lynch, Princeton University
Metabolic Adaptations of Innate Lymphocytes in Tissues |
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Amy Yu, Harvard University
Short Talk: One-Carbon Metabolism Sustains Effector T Cell Function Through Cell-Surface Glycosylation |
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Santosha A Vardhana, Memorial Sloan Kettering Cancer Center
Short Talk: Systemic Iron Sequestration Limits Intratumoral CD8+ T Cell Responses in Pancreas Cancer |
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| 7:00–8:00 PM |
Social Hour with Dinner |
Vancouver Island Room |
| 7:30–10:00 PM |
Poster Session 1 |
British / Columbia Ballroom |
Tuesday, January 13, 2026
| 7:30–8:30 AM |
Breakfast |
Vancouver Island Room |
| 8:30–11:30 AM |
Microbial Metabolites at the Crossroads of Nutrition and Immunity |
Columbia Ballroom |
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Manuela Raffatellu, University of California, San Diego
Microbial-Derived Metabolites at the Host-Pathogen Interface |
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Noah W. Palm, Yale University
Gut Microbiome- Metabolome-Immune Communication Networks |
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Dan R. Littman, HHMI/New York University School of Medicine
Role of Sulfur-Containing Amino Acids on Organismal Immunometabolic Response |
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Sagar P Bapat, University of California, San Francisco
Short Talk: Dietary Timing Dictates Inflammatory Memory in Skin |
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Felix Hartmann, German Cancer Research Center
Short Talk: Spatial Proteomics Identifies Lactate-Competent CD8⁺ T cells as a Feature of Response to Checkpoint Inhibition in Melanoma |
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Andrea Graziani, Università di Torino
Short Talk: Diacylglycerol Kinase alpha (DGKα) Couples Antigen-induced T Cell Activation to the Negative Feedback Mechanism Leading to TCR and CAR Ubiquitination and Lysosomal Degradation |
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Benjamin Y Winer, Memorial Sloan Kettering Cancer Center
Short Talk: Pushing the Envelope: Regulation of Myeloid Plasma Membrane Abundance and its Effect of Cellular Decision Making |
|
| 9:30–9:50 AM |
Coffee Break |
British Columbia Foyer |
| 11:30–1:00 PM |
Poster Setup |
British / Columbia Ballroom |
| 11:30–3:15 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
British / Columbia Ballroom |
| 3:15–4:30 PM |
Meet the Pioneers (Joint) |
Columbia Ballroom |
| 4:30–5:00 PM |
Coffee Available |
British Columbia Foyer |
| 5:00–7:00 PM |
Neuro-Immune Regulation of Immune Function and Metabolism |
Columbia Ballroom |
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Ana Domingos, University of Oxford
Sympathetic Control of Immunity |
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Susan M Kaech, The Salk Institute
Fueling T Cell Responses in Cancer |
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Christina Camell, University of Minnesota
Catecholamines and GDFs in Regulation of Adipose Immunometabolism |
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Judy J Lee, Johns Hopkins University
Short Talk: Lipid Metabolism Regulates Fate Decision of Oligodendrocyte Precursor Cells in Multiple Sclerosis Lesions |
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Ekaterina Vinogradova, Rockefeller University
Short Talk: Chemical Proteomic Approaches to Study and Modulate T Cell Function |
|
| 7:00–8:00 PM |
Social Hour with Dinner |
Vancouver Island Room |
| 7:30–10:00 PM |
Poster Session 2 |
British / Columbia Ballroom |
Wednesday, January 14, 2026
| 7:30–8:30 AM |
Breakfast |
Vancouver Island Room |
| 8:30–11:30 AM |
Immunometabolic Control of Aging and Healthspan |
Columbia Ballroom |
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Vishwa Deep Dixit, Yale University
Immunometabolic Checkpoints of Aging |
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Phillip West, The Jackson Laboratory
Mitochondrial Control of Innate Immunity in Disease and Aging |
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Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne
Talk Title to be Announced |
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Jonathan D. Powell, Calico Life Sciences
The Immunometabolism of Immunoaging |
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Michael S Dahabieh, Van Andel Institute
Short Talk: Immune Checkpoints Reimagined: Lipid–Protein Control of T Cell Exhaustion |
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Farnaz Shamsi, New York University
Short Talk: Inflammaging of the Brown Adipose Immune Niche Orchestrates Age-Related Decline |
|
| 9:30–9:50 AM |
Coffee Break |
British Columbia Foyer |
| 11:30–2:30 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2: Rising Stars |
Columbia Ballroom |
| |
Yae Rin Jeon, Yonsei University College of Medicine, Seoul, South Korea
PPAR-α Reprograms Lipid Metabolism to Define Macrophage Fate in Chronic Mycobacterium Avium Infection |
|
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Sushanth Kumar, Duke University
Understanding the Mechanisms by which Maternal High-Fat Diet Leads to Sex-Specific Dysfunction of the Serotonin System in Offspring |
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Julio Ayala Angulo, University of California, Irvine
CD1a-Mediated Inflammation Modulates Metabolism in High Fat Diet Mouse Model of T2D |
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Megan H Le, University of Washington
Metabolic Profiling Identifies Distinct Immune Cell Phenotypes at the Maternal-Fetal Interface across Pregnancy |
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Corinna Mayer, Karolinska Institutet
Spatial and Functional Dissection of Immune-metabolic Dynamics in the Human Endometrium across the Menstrual Cycle |
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Andrew Monteith, University of Tennessee-Knoxville
Acute Fasting Impairs Neutrophil Metabolism and Exacerbates Susceptibility to Staphylococcus Aureus Bacteremia |
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Noga Ron-Harel, Technion-Israel Institute of Technology
Heme and Iron Toxicity in the Aged Spleen Impairs T-cell Immunity through Iron Deprivation |
|
| 4:30–5:00 PM |
Coffee Available |
British Columbia Foyer |
| 5:00–6:00 PM |
Systems Metabolism in Health and Disease (Joint) |
British / Columbia Ballroom |
| |
Leif S Ludwig, Berlin Institute of Health and Max Delbrück Center for Molecular Medicine
Single-Cell Multi-Omics of Mitochondrial DNA Disorders |
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Stacey D Finley, University of Southern California
Signaling and Metabolic States in Immunotherapy |
|
| 6:00–6:45 PM |
Closing Keynote Address (Joint) |
British / Columbia Ballroom |
| |
Jeffrey C Rathmell, University of Chicago
Immunometabolism in Health and Disease |
|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Joint) |
British / Columbia Ballroom |
| 7:00–8:00 PM |
Social Hour with Dinner |
Vancouver Island Room |
| 8:00–9:00 PM |
Entertainment |
British / Columbia Ballroom |
Thursday, January 15, 2026
