Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease (J3)
January 19-22, 2026
| Fairmont Banff Springs, Banff, AB, Canada
Pieter Dorrestein, Michael A. Fischbach, Neha Garg and Ines Thiele
Scholarship Deadline: Sep. 24, 2025 | Abstract Deadline: Dec. 31, 2025 | Early Registration Deadline: Nov. 21, 2025
| 4:00–8:00 PM |
Registration |
Riverview Lounge |
| 6:00–8:00 PM |
Welcome Mixer |
Riverview Lounge |
Tuesday, January 20, 2026
| 7:00–8:00 AM |
Breakfast |
Alberta/New Brunswick |
| 8:00–8:10 AM |
Welcome Remarks (Joint) |
Cascade Ballroom |
| 8:10–9:30 AM |
Keynote Address (Joint) |
Cascade Ballroom |
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Emily P Balskus, HHMI-Harvard University
Mechanistic Enzymology of Microbiome-Derived Gene Products |
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Mohamed S. Abou Donia, Princeton University
Production and Metabolism of Bioactive Molecules by the Human Microbiome |
|
| 9:30–9:50 AM |
Coffee Break |
Riverview Lounge |
| 10:00–11:30 AM |
Microbial Biochemistry in Health and Disease (Joint) |
Cascade Ballroom |
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Stavroula Hatzios, Yale University
Microbial Modulation of Redox-Active Molecules in the Gut |
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Harry Sokol, Saint-Antoine Hospital
Effect of Microbiome on Energy Metabolism in IBD |
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Tamia A Harris-Tryon, University of Texas Southwestern Medical Center
Host-Microbial Crosstalk at the Skin Surface |
|
| 11:15–12:15 PM |
Meet the Editors (Joint) |
Cascade Ballroom |
| 11:15–1:00 PM |
Poster Setup |
Alberta/New Brunswick |
| 11:15–2:30 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Alberta/New Brunswick |
| 2:30–4:30 PM |
Symposia Spotlight 1 |
Alhambra Ballroom |
| |
Angela Sofia Burkhart Colorado, University of Colorado Anschutz Medical Campus
DietMicrobeNet: A Bioinformatics Tool to Increase Resolution of Diet-Microbe Relationships at the Compound-Enzyme Level Using Networks |
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Jonas Cremer, Stanford University
Quantifying Metabolic Fluxes from the Gut Microbiota to Human Host |
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Jelle Dillen, University of Antwerp
Composition-Driven Discovery of Antimicrobial Metabolites and Peptides From the Vaginal Microbiome |
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Arvid E Gollwitzer, Broad
MetaOmics-10T: An Openly Shareable Foundational Dataset to Unlock AI-Accelerated Discovery in Microbial Ecosystems |
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Erik Hasenoehrl, Brigham and Women's Hospital, Boston Children's Hospital
Identification of Key Bacteria, Genes, and Metabolites in the Microbiota-mediated Metabolism of Bilirubin |
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Caitlin H Kowalski, Dartmouth Hitchcock Medical Center
Mycobiome-Mediated Lipid Transformations in the Skin Microenvironment |
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Andrei Osterman, Stanford Burnham Prebys Medical Discovery Institute
Genomics-Guided Prediction of Microbial Metabolic Phenotypes for Rational Design of Microbiome-Targeted Nutritional Supplements |
|
| 4:30–5:00 PM |
Coffee Available |
Riverview Lounge |
| 5:00–7:00 PM |
Microbiome Metabolites in Immune Regulation and Metabolic Health |
Alhambra Ballroom |
| |
Jacob Folz, ETH Zurich DHEST IFNH
Quantification Of Microbiota Metabolism for Functional Insight to Gut Health |
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Fredrik Bäckhed, University of Gothenburg
Microbiome and Metabolic Signaling in the Gut |
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Changtao Jiang, Peking University Health Science Center
Unlocking the Potential of Gut Microbial Enzymes for Precision Treatment of Metabolic Diseases |
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Margaret Alexander, University of Wisconsin - Madison
Short Talk: Mechanisms of the Microbiota-Dependent Protective Effect of a Ketogenic Diet in Multiple Sclerosis Models |
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Robert Quinn, Michigan State University
Short Talk: Microbially Conjugated Bile Acids as a New Dialect in the Host-Microbiome Crosstalk |
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| 7:00–8:00 PM |
Social Hour with Dinner |
Alberta/New Brunswick |
| 7:30–10:00 PM |
Poster Session 1 |
Alberta/New Brunswick |
Wednesday, January 21, 2026
| 7:00–8:00 AM |
Breakfast |
Alberta/New Brunswick |
| 8:00–11:00 AM |
Emerging Tools to Study Microbiome Derived Metabolites |
Alhambra Ballroom |
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Ines Thiele, University of Galway
Metabolic Models of Microbiome |
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Alexey Melnik, Arome Science Inc.
Quantitative Metabolomics in Microbiome Research |
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Pieter Dorrestein, University of California, San Diego
Speeding up the Process to Discover Microbiome Derived Molecules with Fast Computation, Leveraging Public Data and New Metabolomics Mining Tools |
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Clary B. Clish, Broad Institute of MIT and Harvard
Metabolomics in Human Health |
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Abigail S Gancz, North Carolina State University
Short Talk: Successful Fecal Microbiota Transplants in Recurrent Clostridioides Difficile Patients Are Associated with Lipidomic Shifts in Acylcarnitines and Sphingolipids with Concurrent Shifts in Enterobacteriaceae |
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Simone Zuffa, UC San Diego
Short Talk: A Multi-Organ Murine Metabolomics Atlas Reveals Molecular Dysregulations in Alzheimer’s Disease |
|
| 9:00–9:20 AM |
Coffee Break |
Riverview Lounge |
| 11:00–1:00 PM |
Poster Setup |
Alberta/New Brunswick |
| 11:00–3:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Alberta/New Brunswick |
| 2:00–3:30 PM |
Career Roundtable (Joint) |
Alhambra Ballroom |
| 4:00–5:00 PM |
Coffee Break with Hot Chocolate, Firepits & Mountain Views |
Conservatory Terrace |
| 5:00–7:00 PM |
The Genes that Make Microbial Metabolites |
Alhambra Ballroom |
| |
Marnix Medema, Wageningen University
Elucidating the Functions of Metabolic Gene Clusters in Microbiomes using Computational Omics |
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Sloan Devlin, Harvard Medical School
Gut Microbial Chemistry in Health and Disease |
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Karen D Corbin, AdventHealth Translational Research Institute
Microbial Metabolites as Biomarkers and Mechanistic Influencers of Human Energy Balance |
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Hannah E Augustijn, Wageningen University & Research
Short Talk: Harnessing Microbial Regulatory Networks to Unlock Biosynthetic Potential |
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Caroline E.M.K. Dricot, University of Antwerp
Short Talk: Microdiversity in the Shadows: Functional Specialization and SNP-Driven Overproduction of Vitamins and Indoles in Vaginal Limosilactobacillus |
|
| 7:00–8:00 PM |
Social Hour with Dinner |
Alberta/New Brunswick |
| 7:30–10:00 PM |
Poster Session 2 |
Alberta/New Brunswick |
Thursday, January 22, 2026
| 7:00–8:00 AM |
Breakfast |
Alberta/New Brunswick |
| 8:00–11:00 AM |
Advanced Methods to Study the Microbiome (Joint) |
Cascade Ballroom |
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Donald E. Ingber, Wyss Institute for Biologically Inspired Engineering at Harvard
Analyzing Host-Microbiome Interactions Using Human Organ Chips |
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Jared S Kehe, Concerto Biosciences
Measuring Millions of Microbial Combinations to Unravel the Ecology of the Skin Microbiome |
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Elaine Y. Hsiao, University of California, Los Angeles
Advances in the Gut-Brain Axis |
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Diego R Gelsinger, Columbia University
Short Talk: Metagenomic Editing of Commensal Bacteria in vivo using CRISPR-associated Transposases |
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Nick Burton, Van Andel Institute
Short Talk: A High-Throughput Screening Platform for Identifying Microbiome Produced Metabolites that Regulate Animal Physiology |
|
| 9:00–9:20 AM |
Coffee Break |
Riverview Lounge |
| 9:20–9:25 AM |
Award Recipient Acknowledgement |
Cascade Ballroom |
| 11:00–1:00 PM |
Poster Setup |
Alberta/New Brunswick |
| 11:00–2:30 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Alberta/New Brunswick |
| 2:30–4:30 PM |
Symposia Spotlight 2 |
Alhambra Ballroom |
| |
Tatiana T Marquez-Lago, University of Alabama at Birmingham, Heersink School of Medicine
Human Milk Microbiome-Metabolome Interactions Influence Cytomegalovirus Transmission to Infants |
|
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Jared R Mayers, Fred Hutchinson Cancer Center
Leveraging A Reverse-Translational Framework to Decode In Vivo Microbial Metabolism |
|
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Aleksandra Uryga, Miedzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie
Mapping Microbial Metabolites Beyond the Intestine |
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Gaohua Yang, Wallenberg Laboratory, Sahlgrenska University Hospital
A Microbial Caffeic Acid To 4-Ethylcatechol Funnel In Polyphenol Catabolism Protects Against Diet-Induced Hepatic Steatosis |
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Jacqueline A Barnett, Melius MicroBiomics
Rational Engineering of Escherichia coli Nissle 1917 for Inflammation-Selective Expansion Enables Single-Dose Therapeutic Efficacy and Systemic Metabolic Remodeling in a Translational Porcine Colitis Model |
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Camilo Anthony G Gacasan, Emory University School of Medicine
Beneficial Microbe Driven Rewiring of Metabolic Pathways in the Gut and Liver |
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Chayanika Gogoi, National Institute of Immunology
Nutrient-Driven Microbiome Adaptations Mitigate Salmonella Burden in Mice |
|
| 4:30–5:00 PM |
Coffee Available |
Riverview Lounge |
| 5:00–6:45 PM |
The Metabolism at the Intersection of Microbiome, Host, Drugs and Pathogens |
Alhambra Ballroom |
| |
Casey Michelle Theriot, North Carolina State University
Bile Salt Hydrolases as Regulators of C. difficile Colonization in the Gut |
|
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Neha Garg, Georgia Institute of Technology
A Metabolomics Approach to Dissect Interactions between the Pathogen, the Beneficial Bacteria, and the Host |
|
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Karen L. Madsen, University of Alberta
Talk Title to be Annonced |
|
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Michael Zimmermann, European Molecular Biology Laboratory
Short Talk: Gut Bacteria Generate Prodrugs in situ Increasing Systemic Drug Exposure |
|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Alhambra Ballroom |
| 7:00–8:00 PM |
Social Hour with Dinner |
Alberta/New Brunswick |
| 7:30–10:00 PM |
Poster Session 3 |
Alberta/New Brunswick |
