Human Microbiome: From Models and Mechanism to Medicine (J4)
January 19-22, 2026  | Fairmont Banff Springs, Banff, AB, Canada
Ami S. Bhatt, Tami Lieberman and Harry Sokol
Scholarship Deadline: Sep. 24, 2025 | Abstract Deadline: Dec. 31, 2025 | Early Registration Deadline: Nov. 21, 2025
* Session Chair † Invited but not yet accepted | Program current as of November 4, 2025 2 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, January 19, 2026
4:00–8:00 PM Registration Riverview Lounge
6:00–8:00 PM Welcome Mixer Riverview Lounge
Tuesday, January 20, 2026
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–9:30 AM Welcome and Keynote Session (Joint) Cascade Ballroom
  Emily P Balskus, HHMI-Harvard University
Mechanistic Enzymology of Microbiome-Derived Gene Products
 
  Mohamed S. Abou Donia, Princeton University
Production and Metabolism of Bioactive Molecules by the Human Microbiome
 
9:30–9:50 AM Coffee Break Riverview Lounge
10:00–11:30 AM Microbial Biochemistry in Health and Disease (Joint) Cascade Ballroom
  Stavroula Hatzios, Yale University
Microbial Modulation of Redox-Active Molecules in the Gut
 
  Harry Sokol, Saint-Antoine Hospital
Effect of Microbiome on Energy Metabolism in IBD
 
  Tamia A Harris-Tryon, University of Texas Southwestern Medical Center
Host-Microbial Crosstalk at the Skin Surface
 
11:15–12:15 PM Meet the Editors (Joint) Cascade Ballroom
11:15–1:00 PM Poster Setup Alberta/New Brunswick
11:15–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Alberta/New Brunswick
2:30–4:30 PM Symposia Spotlight 1 Cascade Ballroom
  Anna Ruth Schwarzenbach, University of Oxford
Evolving Pathogen-killing Bacteria as Live Biotherapeutics
 
  Bahtiyar Yilmaz, University of Bern
Cradled By Commensals, Provoked by Inflammation: The Dual Life of Natural Antibodies
 
  Jordana M. Ferro, McMaster University
Evaluation of a Skin Microbiome-Derived Antifungal Compound for the Treatment of Candida albicans and Candida auris Skin Colonization
 
  Jean-Marc Chatel, Micalis Institute
The Microbial Anti-Inflammatory Molecule (MAM) of Faecalibacterium is a Key Protein Processed and Exported to the Envelope
 
  Axel Ranson, INSERM/Institut Pasteur de Paris
Dietary Modulation in a Translational Pig Model Identified Early, Sex-Specific Modifications in the Small Intestinal Microbiome and Metabolome, Along with Changes in Peptidoglycan Remodeling
 
  Jessica A Jana, University of Pittsburgh
Bacterial Translocation Following PD1 Blockade Drives Immunotherapy Response in Melanoma Through Microbiome-Specific T Cell Polarization
 
  Anika Sander †, Technical University of Munich
A Common Polymorphism affecting Intestinal Bilirubin Metabolism alters Microbe-Host Interactions
 
  Nora S. Naegele, University of Copenhagen
Dynamic and Reversible Alterations of the Human Intestinal Barrier: Tracking Systemic Impact and Recovery with Non-Invasive Biomarkers
 
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–7:00 PM Microbe-Host Interactions Cascade Ballroom
  Mahesh S. Desai, Luxembourg Institute of Health
Diet, the Gut Microbiome and Host Health
 
  Ami S. Bhatt, Stanford University
Deciphering Microbe-Host Communication
 
  Ramnik Xavier, Massachusetts General Hospital
Large-Scale Population Studies to Understand the Gut-Immune Axis
 
  Nathalie Rolhion, INSERM
Short Talk: Faecalibacterium prausnitzii EXL01 Exhibits a Specific Peptidoglycan That is Involved in its Anti-Inflammatory Effect in a NOD2-Dependent Way
 
  Meenakshi Chakraborty, Stanford University
Short Talk: Age-Related Microbiome Metabolites Modulate Splicing and Chromatin Accessibility in the Brain
 
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
7:30–10:00 PM Poster Session 1 Alberta/New Brunswick
Wednesday, January 21, 2026
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–11:00 AM Microbe-Microbe Interactions in the Human Microbiome Cascade Ballroom
  Tami Lieberman, Massachusetts Institute of Technology
Evolution of the Skin Microbiome Across Scales
 
  Sur Herrera Paredes, National Autonomous University of Mexico
Population Genetics to Study Evolution in the Human Microbiome
 
  Naama Geva-Zatorsky, Technion Institute of Technology
Functional Plasticity in Microbiota-Host interactions
 
  Benjamin D. Ross, Dartmouth College
Mechanisms and Consequences of Microbial Warfare in the Gut
 
  Isaiah Song, Keio University Institute for Advanced Biosciences
Short Talk: iX-seq: A Droplet Microfluidics Platform For Uncovering Cross-Feeding Interactions In The Human Gut Microbiota
 
  Smita Gopinath, Harvard School of Public Health
Short Talk: Microbiome-mediated Inhibition of Herpes Simplex Virus Infections
 
9:00–9:20 AM Coffee Break Riverview Lounge
11:00–1:00 PM Poster Setup Alberta/New Brunswick
11:00–3:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Alberta/New Brunswick
2:00–3:30 PM Career Roundtable (Joint) Alhambra Ballroom
3:30–4:30 PM Panel Discussion Alhambra Ballroom
4:00–5:00 PM Coffee Break with Hot Chocolate, Firepits & Mountain Views Conservatory Terrace
5:00–7:00 PM In vivo Diversity and Dynamics Cascade Ballroom
  Bernat Olle, Vedanta Biosciences
Development of Potential First-in-Class Live Biotherapeutic Products for Gastrointestinal Diseases
 
  Julie A. Segre, National Institutes of Health
Global Skin Microbiomes and Emerging Fungal Pathogens
 
  Sarah Lebeer, University of Antwerp
Citizen Science to Study the Vaginal Microbiome
 
  Eitan Yaffe, Stanford
Short Talk: Mobilization of Resistance Genes in the Human Gut Under Antibiotic Pressure
 
  Erica T Grant, Luxembourg Institute of Health
Short Talk: Mucin on the Menu: Insights into the Mucus-Associated Microbiome from the LUXFICO Study
 
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
7:30–10:00 PM Poster Session 2 Alberta/New Brunswick
Thursday, January 22, 2026
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–11:00 AM Advanced Methods to Study the Microbiome (Joint) Cascade Ballroom
  Donald E. Ingber, Wyss Institute for Biologically Inspired Engineering at Harvard
Studying the Vaginal Microbiome with Organ-on-a-Chip Methods
 
  Jared Kehe †, Concerto Biosciences
Talk Title to be Announced
 
  Elaine Y. Hsiao, University of California, Los Angeles
Advances in the Gut-Brain Axis
 
  Diego R Gelsinger, Columbia University
Short Talk: Metagenomic Editing of Commensal Bacteria in vivo using CRISPR-associated Transposases
 
  Nick Burton, Van Andel Institute
Short Talk: A High-Throughput Screening Platform for Identifying Microbiome Produced Metabolites that Regulate Animal Physiology
 
9:00–9:20 AM Coffee Break Riverview Lounge
9:20–9:25 AM Award Recipient Acknowledgement Cascade Ballroom
11:00–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2 Cascade Ballroom
  Jim Shaw, Dana-Farber Cancer Institute
Algorithmic Advances in Nanopore Metagenome Assembly Uncover Hidden Strain Diversity and Genome Dynamics
 
  Lindsay S Moffatt, University of Guelph
An Efficient Trigonometry-Based Method for High-Throughput Whole Genome Analysis
 
  Piotr Rozwalak, Friedrich-Schiller-Universität Jena
Mushuvirus is the Most Prevalent Human Gut Bacteriophage Worldwide
 
  Yuya Kiguchi, Stanford University
Small Protein Array of the Human Microbiome is a Modulator of Macrophage Polarization
 
  Lior Lobel, Bar-Ilan University
Unveiling Bacterial Molecular Mechanisms in Cancer Immunotherapy Response: A Novel Metaproteomic Approach
 
  Vincent Charron-Lamoureux, University of California - San Diego
Creating and Searching a Metadata Network Graph for Microbiome Metabolomics
 
  Saria McKeithen-Mead, Stanford University
Capturing Evolution via Gene Transfer in the Gut Microbiome
 
  Jason J Biemond, Amsterdam University Medical Centers
Gut Microbiota and Resistome Dynamics in Sepsis ICU Patients in India; A Large Longitudinal Prospective Cohort Study
 
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–6:45 PM Microbiome Drivers of Disease Cascade Ballroom
  Benjamin Hadida, Exeliom Biosciences
Microbiome-Based Therapeutics for Cancer Treatment
 
  Karine Clément, INSERM / Sorbonne Universite
Diabetes, Obesity and the Gut Microbiome
 
  Premysl Bercik, McMaster University
Microbiome and IBS
 
  Julien Pujo, McMaster University
Short Talk: Bacterial Phospholipids Induce Chronic Abdominal Pain In Patients With Irritable Bowel Syndrome
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Cascade Ballroom
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
8:00–9:00 PM Cash Bar
8:00–9:00 PM Entertainment
Friday, January 23, 2026
12:00–11:59 PM Departure