Neurodevelopmental Disorders: Mechanisms and Therapeutics (J5)
January 19-22, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Tomasz Nowakowski, Xin Jin, Stephan Sanders and Zhaolan (Joe) Zhou
Tuesday, January 19, 2027
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Wednesday, January 20, 2027
| 8:00–9:00 AM |
Welcome and Keynote Address |
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Huda Y. Zoghbi, Baylor College of Medicine
A Journey in Rett Syndrome: From Basic Science Discovery of Causal Gene to Therapies of Patients |
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| 9:00–11:15 AM |
Genetics and Genomics of Neurodevelopmental Disorders |
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Hyejung Won, University of North Carolina, Chapel Hill
Experimental Validation of Common Variants of Neurodevelopmental Disorders |
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Xin Jin, Scripps Research Institute
Massively Parallel Dissection of Gene to Phenotype Relationships using Perturb-seq |
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Thomas Bourgeron, Institut Pasteur
PARIS: Paris Autism Research International Sib-Pair Study |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–12:15 PM |
Meet the Editors |
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| 12:15–1:00 PM |
Poster Setup |
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| 12:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Emerging Technologies in the Study of Neurodevelopmental Disorders |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Genes to Molecular Phenotypes |
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Yukiko Gotoh, University of Tokyo
Genetic and Epigenetic Mechanisms of Cortical Development |
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Willow Coyote-Maestas, University of California, San Francisco
Deep Mutational Scanning Approaches to Correlate Structure and Function of Proteins |
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Sila Ultanir, Francis Crick Institute
Kinase Signaling in Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Thursday, January 21, 2027
| 8:00–11:00 AM |
Circuits to Phenotypes |
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Gabrielle Pouchelon, Cold Spring Harbor Laboratory
Transient Connectivity and Circuit Reprogramming in Cortical Development |
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Guillermina López Bendito, Instituto de Neurociencias
Spontaneous Activity–Gene Program Interplay in Circuits Development: Implications for Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion 1: What to Translate? When to Translate? How to Translate? |
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| 12:00–1:00 PM |
Poster Setup |
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| 12:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Human and Non-Human Models |
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Tomasz Nowakowski, University of California, San Francisco
Establishing Tools for Human Neuroscience |
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Pierre Vanderhaeghen, KU Leuven
Interrogating Human Specific and Neurodevelopmental Risk Genes using Chimeric Models |
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Paola Arlotta, Harvard University
Brain Organoids to Study Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Environment and Experience |
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Zhaolan (Joe) Zhou, University of Pennsylvania
Epigenetic Dissection of Mechanisms underlying Neurodevelopmental Disorders |
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Kristen J. Brennand, Yale School of Medicine
Insights into Gene-Environment Interactions in Neurodevelopmental Disorders |
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Gloria Choi, Massachusetts Institute of Technology
Cytokine Regulation of Brain and Behavior |
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Anca M. Pasca, Stanford University
Neonatal Hypoxia and Pediatric Risk Factors |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion 2: Grand Challenges in NDDs |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Neurmodulation, Biomarkers, and Therapies |
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Stephan Sanders, University of Oxford
Gene Targeting Strategies for Autism and Neurodevelopmental Disorders |
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Allyson Berent, Foundation for Angelman Syndrome Therapeutics/AS2Bio
The Parents’ Journey through Drug Development: Making the IMPOSSIBLE POSSIBLE-The Angelman Syndrome Story |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Saturday, January 23, 2027
