Neurodevelopmental Disorders: Mechanisms and Therapeutics (J5)
January 19-22, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Tomasz Nowakowski, Xin Jin, Stephan Sanders and Zhaolan (Joe) Zhou
Tuesday, January 19, 2027
| 4:00–8:00 PM |
Registration |
|
| 6:00–8:00 PM |
Welcome Mixer |
|
Wednesday, January 20, 2027
| 8:00–9:00 AM |
Welcome and Keynote Address |
|
| |
Huda Y. Zoghbi †, Baylor College of Medicine
A Journey in Rett Syndrome: From Basic Science Discovery of Causal Gene to Therapies of Patients |
|
| 9:00–11:15 AM |
Genetics and Genomics of Neurodevelopmental Disorders |
|
| |
Hyejung Won, University of North Carolina, Chapel Hill
Experimental Validation of Common Variants of Neurodevelopmental Disorders |
|
| |
Xin Jin, Scripps Research Institute
Massively Parallel Dissection of Gene to Phenotype Relationships using Perturb-seq |
|
| |
Thomas Bourgeron †, Institut Pasteur
PARIS: Paris Autism Research International Sib-Pair Study |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:30–9:50 AM |
Coffee Break |
|
| 11:15–12:15 PM |
Meet the Editors |
|
| 12:15–1:00 PM |
Poster Setup |
|
| 12:15–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
|
| 2:30–4:30 PM |
Symposia Spotlight 1: Emerging Technologies in the Study of Neurodevelopmental Disorders |
|
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
|
| 5:00–7:00 PM |
Genes to Molecular Phenotypes |
|
| |
Yukiko Gotoh, University of Tokyo
Genetic and Epigenetic Mechanisms of Cortical Development |
|
| |
Willow Coyote-Maestas, University of California, San Francisco
Deep Mutational Scanning Approaches to Correlate Structure and Function of Proteins |
|
| |
Sila Ultanir, Francis Crick Institute
Kinase Signaling in Neurodevelopmental Disorders |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 7:00–8:00 PM |
Social Hour with Dinner |
|
Thursday, January 21, 2027
| 8:00–11:00 AM |
Circuits to Phenotypes |
|
| |
Gabrielle Pouchelon, Cold Spring Harbor Laboratory
Transient Connectivity and Circuit Reprogramming in Cortical Development |
|
| |
Guillermina López Bendito, Instituto de Neurociencias
Spontaneous Activity–Gene Program Interplay in Circuits Development: Implications for Neurodevelopmental Disorders |
|
| |
Botond Roska †, Institute of Molecular and Clinical Ophthalmology (IOB) Basel
Asynchrony of Functional Connectivity in Developing Brain of ASD Models |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–12:00 PM |
Panel Discussion 1: What to Translate? When to Translate? How to Translate? |
|
| 12:00–1:00 PM |
Poster Setup |
|
| 12:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
|
| 3:00–4:30 PM |
Career Roundtable |
|
| 4:30–5:00 PM |
Coffee Available |
|
| 5:00–7:00 PM |
Human and Non-Human Models |
|
| |
Tomasz Nowakowski, University of California, San Francisco
Establishing Tools for Human Neuroscience |
|
| |
Pierre Vanderhaeghen, KU Leuven
Interrogating Human Specific and Neurodevelopmental Risk Genes using Chimeric Models |
|
| |
Paola Arlotta, Harvard University
Brain Organoids to Study Neurodevelopmental Disorders |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 7:00–8:00 PM |
Social Hour with Dinner |
|
| 8:00–11:00 AM |
Environment and Experience |
|
| |
Zhaolan (Joe) Zhou, University of Pennsylvania
Epigenetic Dissection of Mechanisms underlying Neurodevelopmental Disorders |
|
| |
Kristen J. Brennand, Yale School of Medicine
Insights into Gene-Environment Interactions in Neurodevelopmental Disorders |
|
| |
Gloria Choi, Massachusetts Institute of Technology
Cytokine Regulation of Brain and Behavior |
|
| |
Anca M. Pasca, Stanford University
Neonatal Hypoxia and Pediatric Risk Factors |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–12:00 PM |
Panel Discussion 2: Grand Challenges in NDDs |
|
| 11:00–5:00 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
|
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
|
| 5:00–7:00 PM |
Neurmodulation, Biomarkers, and Therapies |
|
| |
Stephan Sanders, University of Oxford
Gene Targeting Strategies for Autism and Neurodevelopmental Disorders |
|
| |
Allyson Berent, Foundation for Angelman Syndrome Therapeutics/AS2Bio
The Parents’ Journey through Drug Development: Making the IMPOSSIBLE POSSIBLE-The Angelman Syndrome Story |
|
| |
Cassiano Carromeu †, Recursion
Using Human Pluripotent Stem Cell-Derived Neural Cultures to Assess Safety of New Drugs and Chemicals |
|
| |
Short Talk(s) Chosen from Abstracts
|
|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
|
| 7:00–8:00 PM |
Social Hour with Dinner |
|
| 8:00–11:00 PM |
Entertainment |
|
Saturday, January 23, 2027
