Neurodevelopmental Disorders: Mechanisms and Therapeutics (J5)
January 19-22, 2027
| Beaver Run Conference Center, Breckenridge, CO, United States
Tomasz Nowakowski, Xin Jin, Stephan Sanders and Zhaolan (Joe) Zhou
Scholarship Deadline: Sep. 25, 2026 | Abstract Deadline: Dec. 30, 2026 | Early Registration Deadline: Nov. 20, 2026
Tuesday, January 19, 2027
| 4:00–8:00 PM |
Registration |
Colorado Ballroom Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
Colorado Ballroom Foyer |
Wednesday, January 20, 2027
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–8:10 AM |
Welcome Remarks |
Breckenridge Ballroom |
| 8:10–9:00 AM |
Keynote Address |
Breckenridge Ballroom |
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Huda Y. Zoghbi, Baylor College of Medicine
A Journey in Rett Syndrome: From Basic Science Discovery of Causal Gene to Therapies of Patients |
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| 9:00–11:15 AM |
Decoding Variant Effects: From Population Genomics to Functional Consequences |
Breckenridge Ballroom |
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Hyejung Won, University of North Carolina, Chapel Hill
Experimental Validation of Common Variants of Neurodevelopmental Disorders |
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Xin Jin, Scripps Research Institute
Massively Parallel Dissection of Gene to Phenotype Relationships Using Perturb-seq |
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Thomas Bourgeron, Institut Pasteur
The Genetic Orchestra of Autism: From Medicine to Neurodiversity |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
Breckenridge Ballroom Foyer |
| 11:25–12:25 PM |
Meet the Editors |
Breckenridge Ballroom |
| 12:25–1:00 PM |
Poster Setup |
Colorado Ballroom Peak 1-3 |
| 12:25–2:30 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Colorado Ballroom Peak 1-3 |
| 2:30–4:30 PM |
Symposia Spotlight 1: Emerging Technologies in the Study of Neurodevelopmental Disorders |
Breckenridge Ballroom |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
Breckenridge Ballroom Foyer |
| 5:00–7:00 PM |
Molecular Mechanisms Linking Gene Dysregulation to Protein Function and Cellular Phenotypes |
Breckenridge Ballroom |
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Yukiko Gotoh, University of Tokyo
Genetic and Epigenetic Mechanisms of Cortical Development |
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Willow Coyote-Maestas, University of California, San Francisco
Deep Mutational Scanning Approaches to Correlate Structure and Function of Proteins |
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Sila Ultanir, Francis Crick Institute
Kinase Signaling in Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
Summit Gallery |
| 7:30–10:00 PM |
Poster Session 1 |
Colorado Ballroom Peak 1-3 |
Thursday, January 21, 2027
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–11:00 AM |
Circuit Dynamics Shaping Developmental Outcomes |
Breckenridge Ballroom |
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Gabrielle Pouchelon, Cold Spring Harbor Laboratory
Transient Connectivity and Circuit Reprogramming in Cortical Development |
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Guillermina López Bendito, Instituto de Neurociencias
Spontaneous Activity–Gene Program Interplay in Circuits Development: Implications for Neurodevelopmental Disorders |
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Liqun Luo, Stanford University
Wiring Specificity of Neural Circuits |
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Weizhe Hong, UCLA Los Angeles
The Neuroscience of Prosocial Behavior: From Helping and Cooperation to Social AI |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Breckenridge Ballroom Foyer |
| 11:10–12:10 PM |
Panel Discussion 1: What to Translate? When to Translate? How to Translate? |
Breckenridge Ballroom |
| 12:10–1:00 PM |
Poster Setup |
Colorado Ballroom Peak 1-3 |
| 12:10–3:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Colorado Ballroom Peak 1-3 |
| 3:00–4:30 PM |
Career Roundtable (Joint) |
Colorado Ballroom Peak 4-5 |
| 4:30–5:00 PM |
Coffee Available |
Breckenridge Ballroom Foyer |
| 5:00–7:00 PM |
Experimental Models for Interrogating Human Specific Neurodevelopmental Mechanisms |
Breckenridge Ballroom |
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Tomasz Nowakowski, University of California, San Francisco
Establishing Tools for Human Neuroscience |
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Pierre Vanderhaeghen, KU Leuven
Interrogating Human Specific and Neurodevelopmental Risk Genes using Chimeric Models |
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Paola Arlotta, Harvard University
Brain Organoids to Study Neurodevelopmental Disorders |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
Summit Gallery |
| 7:30–10:00 PM |
Poster Session 2 |
Colorado Ballroom Peak 1-3 |
| 7:00–8:00 AM |
Breakfast |
Summit Gallery |
| 8:00–11:00 AM |
Environment and Experience |
Breckenridge Ballroom |
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Zhaolan (Joe) Zhou, University of Pennsylvania
Epigenetic Dissection of Mechanisms underlying Neurodevelopmental Disorders |
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Kristen J. Brennand, Yale School of Medicine
Insights into Gene-Environment Interactions in Neurodevelopmental Disorders |
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Gloria Choi, Massachusetts Institute of Technology
Cytokine Regulation of Brain and Behavior |
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Anca M. Pasca, Stanford University
Neonatal Hypoxia and Pediatric Risk Factors |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Breckenridge Ballroom Foyer |
| 11:10–12:10 PM |
Panel Discussion 2: Grand Challenges in NDDs |
Breckenridge Ballroom |
| 12:10–2:30 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2 |
Breckenridge Ballroom |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
Breckenridge Ballroom Foyer |
| 5:00–6:15 PM |
From Genetic Targets to Therapeutic Strategies |
Breckenridge Ballroom |
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Stephan Sanders, University of Oxford
Gene Targeting Strategies for Autism and Neurodevelopmental Disorders |
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Joe Gleeson, University of California, San Diego
Lessons from Neurodevelopmental Disease |
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Short Talk(s) Chosen from Abstracts
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| 6:15–7:05 PM |
Closing Keynote Address |
Breckenridge Ballroom |
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Allyson Berent, Foundation for Angelman Syndrome Therapeutics/AS2Bio
The Parents’ Journey through Drug Development: Making the IMPOSSIBLE POSSIBLE-The Angelman Syndrome Story |
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| 7:05–7:15 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
Breckenridge Ballroom |
| 7:15–8:15 PM |
Social Hour with Dinner |
Summit Gallery |
| 8:00–9:00 PM |
Entertainment |
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Saturday, January 23, 2027
