HIV and (Re)Emerging Viruses: Aligning Lessons Across Pandemics (K1)
April 8-11, 2024  | Herrenhausen Palace, Hannover, Germany
Melanie M. Ott, Priti Kumar, Olivier Schwartz and Alex Sigal
Scholarship Deadline: Jan. 17, 2024 | Abstract Deadline: Jan. 17, 2024 | Early Registration Deadline: Feb. 7, 2024
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 8 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, April 8, 2024
4:00–8:00 PM Registration Grand Mussmann Hotel, Tivoli Room
6:00–8:00 PM Welcome Mixer Central-Hotel Kaiserhof
Tuesday, April 9, 2024
8:00–9:00 AM Breakfast Individual Hotel
8:30–9:00 AM Poster Setup Foyer
9:00–10:00 AM Welcome and Keynote Address Auditorium
  Sarah Catherine Gilbert, University of Oxford
Preparing to Vaccinate Against the Next Pandemic
 
9:00–7:00 PM Poster Viewing Foyer
10:00–12:15 PM Pathogenesis I- Viral Emergence Auditorium
  Stefan Pöhlmann, Deutsches Primatenzentrum GmbH
Principles of Coronaviral Infections
 
  Geoffrey L. Smith, University of Oxford
Host-Virus Interactions with Monkeypox Virus
 
  Jérémy Dufloo, Universitat de València
Short Talk: Short Talk: Viral Entry is a Weak Barrier to Zoonosis
 
  Paige Fletcher, NIAID, NIH
Short Talk: Short Talk: Taï Forest Virus: The Virus Sequence Determines the Pathogenic Potential
 
  Max Josef J Kellner, IMBA
Short Talk: Short Talk: Bat Organoids: Understanding Emerging Virus Infections through the Lens of Reservoir Species
 
10:30–10:50 AM Coffee Break Foyer
12:15–1:15 PM Lunch Ballroom
1:00–3:00 PM Poster Session 1 Foyer
3:30–4:30 PM Career Roundtable Auditorium
  Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases
Research Chair & Professor
 
  Joel N. Blankson, Johns Hopkins School of Medicine
Professor of Medicine
 
  Irini Sereti, NIAID, National Institutes of Health
Senior Investigator
 
  Valentin Le Douce, BioNTech SE
Associate Director - Infectious Disease Vaccines
 
4:30–5:00 PM Coffee Available Foyer
5:00–7:00 PM Pathogenesis II- Molecular Mechanisms Auditorium
  Melanie M. Ott, Gladstone Institute of Virology
How Viral Proteins Shape HIV and SARS-CoV-2 Pathogenesis
 
  Wendy Barclay, Imperial College London
Lessons Learned from Flu and SARS-CoV-2
 
  Kei Sato, The University of Tokyo
Pathogenicity of Omicron Subvariants
 
  Sharon R. Lewin, University of Melbourne
mRNA Therapeutics for SARS-CoV2 and HIV latency
 
  Lisa Lasswitz, University of Veterinary Medicine Hannover
Short Talk: Short Talk: CD81 is a Host Factor for Chikungunya Virus Replication
 
7:00–8:00 PM Social Hour with Lite Bites Ballroom
Wednesday, April 10, 2024
8:00–9:00 AM Breakfast Individual Hotel
8:30–9:00 AM Poster Setup Foyer
9:00–12:00 PM Common Lessons in Prevention Auditorium
  Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases
Antibody Responses in People Living with HIV
 
  Olivier Schwartz, Institut Pasteur
Entry and Replication of Human Seasonal Coronaviruses and Recent SARS-CoV-2 Variants
 
  Joel N. Blankson, Johns Hopkins School of Medicine
Natural Immunity to HIV
 
  Daniel Lingwood, Harvard Medical School
Short Talk: Short Talk: Eliciting a Single Amino Acid Change by Vaccination Enables Cross-Group Protective Influenza Antibodies
 
  Matthew Sutton, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health
Short Talk: Short Talk: Evaluating Mechanisms of Protection by Broadly Reactive Anti-Alphavirus Antibodies
 
9:00–7:00 PM Poster Viewing Foyer
10:00–10:20 AM Coffee Break Foyer
12:00–1:00 PM Lunch Ballroom
12:30–2:30 PM Poster Session 2 Foyer
2:30–4:30 PM Workshop 1 Auditorium
  Ulrike Lange, Heinrich Pette Institute
Transcriptional Activity of Proviral Sequences as Driver for Clonal Expansion in Chronic HIV Infection
 
  Dania Figueroa Acosta, Icahn School of Medicine at Mount Sinai
Endocytic Recycling-Dependent Env Antigenic States Affect Neutralization of Cell-Free and Cell-Cell Infection by Broadly Neutralizing Antibodies
 
  Uwem Etop George, African Centre of Excellence for Genomics of Infectious Diseases
Whole Genome Sequencing Reveals Cryptic Circulation of Dengue Virus in the Rainforest Region of Nigeria, West Africa
 
  Shlomi Ilan, Ragon Institute of MGH, MIT and Harvard
Functional Antibody Signatures Following Combined Active and Passive Therapeutic Immunization of SHIV-infected Rhesus Macaques
 
  Nell Saunders, Institut Pasteur
TMPRSS2 is a Functional Receptor for Human Coronavirus HKU1
 
  Taha Y. Taha, Gladstone Institutes/UCSF
Spike-Independent Evolution of Recent SARS-CoV-2 Omicron Subvariants Enhances Viral RNA Replication via NSP6 Mutations
 
  Florian Kabinger, Max Planck Institute for Multidisciplinary Sciences
Uncovering the Mechanism of Small Molecule Inhibitors Against the RNA Polymerase of SARS-CoV-2
 
4:30–5:00 PM Coffee Available Foyer
5:00–7:00 PM Drivers of Viral Evolution Auditorium
  Alex Sigal, Africa Health Research Institute
SARS-CoV-2 Evolution and Pathogenesis in PLWH
 
  Ravindra K. Gupta, University of Cambridge
SARS-CoV-2 Spike Evolution – Balancing Infectivity with Immune Evasion
 
  Emma Hodcroft, University of Basel
Evolution of HIV and Other Viruses
 
  Ann-Kathrin Reuschl, University College London
Short Talk: Short Talk: SARS-CoV-2 Evolution of Innate Immune Antagonism
 
7:00–8:00 PM Social Hour with Lite Bites Ballroom
Thursday, April 11, 2024
8:00–9:00 AM Breakfast Individual Hotel
9:00–12:00 PM Pushing the Boundaries on Viral Therapeutics Auditorium
  Priti Kumar, Yale School of Medicine
HIV Gene Therapy: A Time to Prevent, a Time to Control, and Now, the Time to Cure
 
  Galit Alter, Moderna, Inc.
Antibodies Therapeutics in HIV, SARS, Flu, and RSV
 
  Michael Z. Lin, Stanford University School of Medicine
Short Talk: Short Talk: Design of Oral Antiviral Drugs for Broad-Spectrum Activity Against Coronaviruses
 
  Vijayakumar Velu, Emory University
Short Talk: Short Talk: IL-15/IL-15Ra Cytokine Therapy Leads to Control of Viral Rebound in SIV Infected Macaques
 
  Tomas Raul Wiche Salinas, Emory University
Short Talk: Short Talk: Persistent Reduction of SIV Reservoir Through Short-Term BCL-2 Inhibition at ART Initiation in Rhesus Macaques
 
10:00–10:20 AM Coffee Break Foyer
12:00–1:00 PM Lunch Ballroom
1:00–2:30 PM Hands-On Computer Workshop on Los Alamos HIV Sequence and Immunology Databases and Tools (HIV.lanl.gov) Auditorium
  Brian T. Foley, Los Alamos National Lab
Los Alamos National Lab
 
  Jennifer Mamrosh, Los Alamos National Laboratory
Los Alamos National Lab
 
2:30–4:30 PM Workshop 2 Auditorium
  Maria C Hesselman, University of Zurich
Distinct V2 Apex Broadly Neutralizing Antibody Modalities in Subtype B HIV-1 Infection
 
  Doan C. Nguyen, Emory University
The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination
 
  Sharidan Brown, Scripps Research
Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens
 
  Enrico Bravo, King's College London
IFNα2 Autoantibodies Post SARS-CoV-2 Wave 1 in India Are Associated with Lower Omicron Symptomology
 
  Julia Hitschfel, Ragon Institute of MGH, MIT and Harvard
Transcriptional Profiling of HIV-Specific CD8 T Cell Responses From Lymph Nodes and Blood of Natural Controllers
 
  Nicholas Provine, University of Oxford
Immune Signatures Associated with Failure to Seroconvert in Individuals Immunized with MVA-BN as a Vaccine Against MPOX
 
  Wilfredo Garcia-Beltran, Ragon Institute of Mass General, MIT and Harvard
Evasion of NKG2D-Mediated Cytotoxic Immunity by Sarbecoviruses
 
  Adam Zuiani, BioNTech US
A Multivalent mRNA Monkeypox Virus Vaccine (BNT166) Protects Mice and Macaques From Orthopoxvirus Disease
 
4:30–5:00 PM Coffee Available Foyer
5:00–6:45 PM Plenary PM Auditorium
6:45–7:00 PM Post-Acute Sequelae of Viral Infections Auditorium
  Nadia R. Roan, University of California, San Francisco
Post-Acute Sequelae of COVID-19
 
  Gabriella Worwa, NIH/NIAID/IRF-Frederick
Modeling Post-Acute Sequelae of Ebola Virus Disease
 
  Irini Sereti, NIAID, National Institutes of Health
HIV and Chronic Immune Activation: The Impact of Low Nadir CD4 Counts
 
  Till Omansen, Bernhard-Nocht-Institut für Tropenmedizin
Short Talk: Short Talk: Lassa Fever is Hallmarked by Inflammation and Kidney Injury or Neurological Disease: Results from the Lassa Fever PATHOGENESIS Study
 
7:00–8:00 PM Social Hour with Lite Bites Ballroom
Friday, April 12, 2024
12:00–11:59 PM Departure