HIV and (Re)Emerging Viruses: Aligning Lessons Across Pandemics (K1)
      
      
      
      
      
      April 8-11, 2024
       | Herrenhausen Palace, Hannover, Germany
      
      
      
         
          Melanie M. Ott, Priti Kumar, Olivier Schwartz and Alex Sigal
        
            
      
      
      
          Scholarship Deadline: Jan. 17, 2024 | Abstract Deadline: Jan. 17, 2024 | Early Registration Deadline: Feb. 7, 2024
      
   
            
     
          
    
      
      
        
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 4:00–8:00 PM | 
            Registration | 
            Grand Mussmann Hotel, Tivoli Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 6:00–8:00 PM | 
            Welcome Mixer | 
            Central-Hotel Kaiserhof | 
          
        
        
        
         
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–9:00 AM | 
            Breakfast | 
            Individual Hotel | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:30–9:00 AM | 
            Poster Setup | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 9:00–10:00 AM | 
            Welcome and Keynote Address | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Sarah Catherine Gilbert, University of Oxford Preparing to Vaccinate Against the Next Pandemic | 
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            | 9:00–7:00 PM | 
            Poster Viewing | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 10:00–12:15 PM | 
            Pathogenesis I- Viral Emergence  | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Stefan Pöhlmann, Deutsches Primatenzentrum GmbH Principles of Coronaviral Infections | 
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            |   | 
            Geoffrey L. Smith, University of Oxford Host-Virus Interactions with Monkeypox Virus | 
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            |   | 
            Jérémy Dufloo, Universitat de València Short Talk: Short Talk: Viral Entry is a Weak Barrier to Zoonosis | 
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            |   | 
            Paige Fletcher, NIAID, NIH Short Talk: Short Talk: Taï Forest Virus: The Virus Sequence Determines the Pathogenic Potential | 
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            |   | 
            Max Josef J Kellner, IMBA Short Talk: Short Talk: Bat Organoids: Understanding Emerging Virus Infections through the Lens of Reservoir Species | 
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            | 10:30–10:50 AM | 
            Coffee Break | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 12:15–1:15 PM | 
            Lunch | 
            Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 1:00–3:00 PM | 
            Poster Session 1 | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 3:30–4:30 PM | 
            Career Roundtable | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases Research Chair & Professor | 
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            |   | 
            Joel N. Blankson, Johns Hopkins School of Medicine Professor of Medicine | 
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            |   | 
            Irini Sereti, NIAID, National Institutes of Health Senior Investigator | 
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            |   | 
            Valentin Le Douce, BioNTech SE Associate Director - Infectious Disease Vaccines | 
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            | 4:30–5:00 PM | 
            Coffee Available | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 5:00–7:00 PM | 
            Pathogenesis II- Molecular Mechanisms | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Melanie M. Ott, Gladstone Institute of Virology How Viral Proteins Shape HIV and SARS-CoV-2 Pathogenesis | 
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            |   | 
            Wendy Barclay, Imperial College London Lessons Learned from Flu and SARS-CoV-2 | 
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            |   | 
            Kei Sato, The University of Tokyo Pathogenicity of Omicron Subvariants | 
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            |   | 
            Sharon R. Lewin, University of Melbourne mRNA Therapeutics for SARS-CoV2 and HIV latency | 
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            |   | 
            Lisa Lasswitz, University of Veterinary Medicine Hannover Short Talk: Short Talk: CD81 is a Host Factor for Chikungunya Virus Replication | 
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            | 7:00–8:00 PM | 
            Social Hour with Lite Bites | 
            Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
        
          
            Wednesday, April 10, 2024
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–9:00 AM | 
            Breakfast | 
            Individual Hotel | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:30–9:00 AM | 
            Poster Setup | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 9:00–12:00 PM | 
            Common Lessons in Prevention | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases Antibody Responses in People Living with HIV | 
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            |   | 
            Olivier Schwartz, Institut Pasteur Entry and Replication of Human Seasonal Coronaviruses and Recent SARS-CoV-2 Variants | 
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            |   | 
            Joel N. Blankson, Johns Hopkins School of Medicine Natural Immunity to HIV | 
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            |   | 
            Daniel Lingwood, Harvard Medical School Short Talk: Short Talk: Eliciting a Single Amino Acid Change by Vaccination Enables Cross-Group Protective Influenza Antibodies | 
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            |   | 
            Matthew Sutton, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health Short Talk: Short Talk: Evaluating  Mechanisms of Protection by Broadly Reactive Anti-Alphavirus Antibodies | 
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            | 9:00–7:00 PM | 
            Poster Viewing | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 10:00–10:20 AM | 
            Coffee Break | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 12:00–1:00 PM | 
            Lunch | 
            Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 12:30–2:30 PM | 
            Poster Session 2 | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 2:30–4:30 PM | 
            Workshop 1 | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Ulrike Lange, Heinrich Pette Institute Transcriptional Activity of Proviral Sequences as Driver for Clonal Expansion in Chronic HIV Infection | 
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            |   | 
            Dania Figueroa Acosta, Icahn School of Medicine at Mount Sinai Endocytic Recycling-Dependent Env Antigenic States Affect Neutralization of Cell-Free and Cell-Cell Infection by Broadly Neutralizing Antibodies | 
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            |   | 
            Uwem Etop George, African Centre of Excellence for Genomics of Infectious Diseases Whole Genome Sequencing Reveals Cryptic Circulation of Dengue Virus in the Rainforest Region of Nigeria, West Africa | 
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            |   | 
            Shlomi Ilan, Ragon Institute of MGH, MIT and Harvard Functional Antibody Signatures Following Combined Active and Passive Therapeutic Immunization of SHIV-infected Rhesus Macaques | 
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            |   | 
            Nell Saunders, Institut Pasteur TMPRSS2 is a Functional Receptor for Human Coronavirus HKU1 | 
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            |   | 
            Taha Y. Taha, Gladstone Institutes/UCSF Spike-Independent Evolution of Recent SARS-CoV-2 Omicron Subvariants Enhances Viral RNA Replication via NSP6 Mutations | 
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            |   | 
            Florian Kabinger, Max Planck Institute for Multidisciplinary Sciences Uncovering the Mechanism of Small Molecule Inhibitors Against the RNA Polymerase of SARS-CoV-2 | 
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            | 4:30–5:00 PM | 
            Coffee Available | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 5:00–7:00 PM | 
            Drivers of Viral Evolution | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Alex Sigal, Africa Health Research Institute SARS-CoV-2 Evolution and Pathogenesis in PLWH | 
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            |   | 
            Ravindra K. Gupta, University of Cambridge SARS-CoV-2 Spike Evolution – Balancing Infectivity with Immune Evasion | 
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            |   | 
            Emma Hodcroft, University of Basel Evolution of HIV and Other Viruses | 
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            |   | 
            Ann-Kathrin Reuschl, University College London Short Talk: Short Talk: SARS-CoV-2 Evolution of Innate Immune Antagonism | 
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            | 7:00–8:00 PM | 
            Social Hour with Lite Bites | 
            Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–9:00 AM | 
            Breakfast | 
            Individual Hotel | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 9:00–12:00 PM | 
            Pushing the Boundaries on Viral Therapeutics | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Priti Kumar, Yale School of Medicine HIV Gene Therapy: A Time to Prevent, a Time to Control, and Now, the Time to Cure | 
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            |   | 
            Galit Alter, Moderna, Inc. Antibodies Therapeutics in HIV, SARS, Flu, and RSV | 
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            |   | 
            Michael Z. Lin, Stanford University School of Medicine Short Talk: Short Talk: Design of Oral Antiviral Drugs for Broad-Spectrum Activity Against Coronaviruses | 
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            |   | 
            Vijayakumar Velu, Emory University Short Talk: Short Talk: IL-15/IL-15Ra Cytokine Therapy Leads to Control of Viral Rebound in SIV Infected Macaques | 
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            |   | 
            Tomas Raul Wiche Salinas, Emory University Short Talk: Short Talk: Persistent Reduction of SIV Reservoir Through Short-Term BCL-2 Inhibition at ART Initiation in Rhesus Macaques | 
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            | 10:00–10:20 AM | 
            Coffee Break | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 12:00–1:00 PM | 
            Lunch | 
            Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 1:00–2:30 PM | 
            Hands-On Computer Workshop on Los Alamos HIV Sequence and Immunology Databases and Tools (HIV.lanl.gov) | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Brian T. Foley, Los Alamos National Lab Los Alamos National Lab | 
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            |   | 
            Jennifer Mamrosh, Los Alamos National Laboratory Los Alamos National Lab | 
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            | 2:30–4:30 PM | 
            Workshop 2 | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Maria C Hesselman, University of Zurich Distinct V2 Apex Broadly Neutralizing Antibody Modalities in Subtype B HIV-1 Infection | 
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            |   | 
            Doan C. Nguyen, Emory University The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination | 
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            |   | 
            Sharidan Brown, Scripps Research Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens | 
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            |   | 
            Enrico Bravo, King's College London IFNα2 Autoantibodies Post SARS-CoV-2 Wave 1 in India Are Associated with Lower Omicron Symptomology | 
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            |   | 
            Julia Hitschfel, Ragon Institute of MGH, MIT and Harvard Transcriptional Profiling of HIV-Specific CD8 T Cell Responses From Lymph Nodes and Blood of Natural Controllers | 
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            |   | 
            Nicholas Provine, University of Oxford Immune Signatures Associated with Failure to Seroconvert in Individuals Immunized with MVA-BN as a Vaccine Against MPOX | 
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            |   | 
            Wilfredo Garcia-Beltran, Ragon Institute of Mass General, MIT and Harvard Evasion of NKG2D-Mediated Cytotoxic Immunity by Sarbecoviruses | 
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            |   | 
            Adam Zuiani, BioNTech US A Multivalent mRNA Monkeypox Virus Vaccine (BNT166) Protects Mice and Macaques From Orthopoxvirus Disease | 
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            | 4:30–5:00 PM | 
            Coffee Available | 
            Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 5:00–6:45 PM | 
            Plenary PM | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 6:45–7:00 PM | 
            Post-Acute Sequelae of Viral Infections | 
            Auditorium | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Nadia R. Roan, University of California, San Francisco Post-Acute Sequelae of COVID-19 | 
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            |   | 
            Gabriella Worwa, NIH/NIAID/IRF-Frederick Modeling Post-Acute Sequelae of Ebola Virus Disease | 
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            |   | 
            Irini Sereti, NIAID, National Institutes of Health HIV and Chronic Immune Activation: The Impact of Low Nadir CD4 Counts | 
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            |   | 
            Till Omansen, Bernhard-Nocht-Institut für Tropenmedizin Short Talk: Short Talk: Lassa Fever is Hallmarked by Inflammation and Kidney Injury or Neurological Disease: Results from the Lassa Fever PATHOGENESIS Study | 
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            | 7:00–8:00 PM | 
            Social Hour with Lite Bites | 
            Ballroom |