HIV and (Re)Emerging Viruses: Aligning Lessons Across Pandemics (K1)
April 8-11, 2024
| Herrenhausen Palace, Hannover, Germany
Melanie M. Ott, Priti Kumar, Olivier Schwartz and Alex Sigal
Scholarship Deadline: Jan. 17, 2024 | Abstract Deadline: Jan. 17, 2024 | Early Registration Deadline: Feb. 7, 2024
4:00–8:00 PM |
Registration |
Grand Mussmann Hotel, Tivoli Room |
6:00–8:00 PM |
Welcome Mixer |
Central-Hotel Kaiserhof |
8:00–9:00 AM |
Breakfast |
Individual Hotel |
8:30–9:00 AM |
Poster Setup |
Foyer |
9:00–10:00 AM |
Welcome and Keynote Address |
Auditorium |
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Sarah Catherine Gilbert, University of Oxford Preparing to Vaccinate Against the Next Pandemic |
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9:00–7:00 PM |
Poster Viewing |
Foyer |
10:00–12:15 PM |
Pathogenesis I- Viral Emergence |
Auditorium |
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Stefan Pöhlmann, Deutsches Primatenzentrum GmbH Principles of Coronaviral Infections |
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Geoffrey L. Smith, University of Oxford Host-Virus Interactions with Monkeypox Virus |
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Jérémy Dufloo, Universitat de València Short Talk: Short Talk: Viral Entry is a Weak Barrier to Zoonosis |
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Paige Fletcher, NIAID, NIH Short Talk: Short Talk: Taï Forest Virus: The Virus Sequence Determines the Pathogenic Potential |
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Max Josef J Kellner, IMBA Short Talk: Short Talk: Bat Organoids: Understanding Emerging Virus Infections through the Lens of Reservoir Species |
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10:30–10:50 AM |
Coffee Break |
Foyer |
12:15–1:15 PM |
Lunch |
Ballroom |
1:00–3:00 PM |
Poster Session 1 |
Foyer |
3:30–4:30 PM |
Career Roundtable |
Auditorium |
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Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases Research Chair & Professor |
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Joel N. Blankson, Johns Hopkins School of Medicine Professor of Medicine |
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Irini Sereti, NIAID, National Institutes of Health Senior Investigator |
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Valentin Le Douce, BioNTech SE Associate Director - Infectious Disease Vaccines |
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4:30–5:00 PM |
Coffee Available |
Foyer |
5:00–7:00 PM |
Pathogenesis II- Molecular Mechanisms |
Auditorium |
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Melanie M. Ott, Gladstone Institute of Virology How Viral Proteins Shape HIV and SARS-CoV-2 Pathogenesis |
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Wendy Barclay, Imperial College London Lessons Learned from Flu and SARS-CoV-2 |
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Kei Sato, The University of Tokyo Pathogenicity of Omicron Subvariants |
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Sharon R. Lewin, University of Melbourne mRNA Therapeutics for SARS-CoV2 and HIV latency |
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Lisa Lasswitz, University of Veterinary Medicine Hannover Short Talk: Short Talk: CD81 is a Host Factor for Chikungunya Virus Replication |
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7:00–8:00 PM |
Social Hour with Lite Bites |
Ballroom |
Wednesday, April 10, 2024
8:00–9:00 AM |
Breakfast |
Individual Hotel |
8:30–9:00 AM |
Poster Setup |
Foyer |
9:00–12:00 PM |
Common Lessons in Prevention |
Auditorium |
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Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases Antibody Responses in People Living with HIV |
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Olivier Schwartz, Institut Pasteur Entry and Replication of Human Seasonal Coronaviruses and Recent SARS-CoV-2 Variants |
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Joel N. Blankson, Johns Hopkins School of Medicine Natural Immunity to HIV |
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Daniel Lingwood, Harvard Medical School Short Talk: Short Talk: Eliciting a Single Amino Acid Change by Vaccination Enables Cross-Group Protective Influenza Antibodies |
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Matthew Sutton, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health Short Talk: Short Talk: Evaluating Mechanisms of Protection by Broadly Reactive Anti-Alphavirus Antibodies |
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9:00–7:00 PM |
Poster Viewing |
Foyer |
10:00–10:20 AM |
Coffee Break |
Foyer |
12:00–1:00 PM |
Lunch |
Ballroom |
12:30–2:30 PM |
Poster Session 2 |
Foyer |
2:30–4:30 PM |
Workshop 1 |
Auditorium |
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Ulrike Lange, Heinrich Pette Institute Transcriptional Activity of Proviral Sequences as Driver for Clonal Expansion in Chronic HIV Infection |
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Dania Figueroa Acosta, Icahn School of Medicine at Mount Sinai Endocytic Recycling-Dependent Env Antigenic States Affect Neutralization of Cell-Free and Cell-Cell Infection by Broadly Neutralizing Antibodies |
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Uwem Etop George, African Centre of Excellence for Genomics of Infectious Diseases Whole Genome Sequencing Reveals Cryptic Circulation of Dengue Virus in the Rainforest Region of Nigeria, West Africa |
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Shlomi Ilan, Ragon Institute of MGH, MIT and Harvard Functional Antibody Signatures Following Combined Active and Passive Therapeutic Immunization of SHIV-infected Rhesus Macaques |
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Nell Saunders, Institut Pasteur TMPRSS2 is a Functional Receptor for Human Coronavirus HKU1 |
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Taha Y. Taha, Gladstone Institutes/UCSF Spike-Independent Evolution of Recent SARS-CoV-2 Omicron Subvariants Enhances Viral RNA Replication via NSP6 Mutations |
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Florian Kabinger, Max Planck Institute for Multidisciplinary Sciences Uncovering the Mechanism of Small Molecule Inhibitors Against the RNA Polymerase of SARS-CoV-2 |
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4:30–5:00 PM |
Coffee Available |
Foyer |
5:00–7:00 PM |
Drivers of Viral Evolution |
Auditorium |
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Alex Sigal, Africa Health Research Institute SARS-CoV-2 Evolution and Pathogenesis in PLWH |
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Ravindra K. Gupta, University of Cambridge SARS-CoV-2 Spike Evolution – Balancing Infectivity with Immune Evasion |
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Emma Hodcroft, University of Basel Evolution of HIV and Other Viruses |
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Ann-Kathrin Reuschl, University College London Short Talk: Short Talk: SARS-CoV-2 Evolution of Innate Immune Antagonism |
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7:00–8:00 PM |
Social Hour with Lite Bites |
Ballroom |
8:00–9:00 AM |
Breakfast |
Individual Hotel |
9:00–12:00 PM |
Pushing the Boundaries on Viral Therapeutics |
Auditorium |
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Priti Kumar, Yale School of Medicine HIV Gene Therapy: A Time to Prevent, a Time to Control, and Now, the Time to Cure |
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Galit Alter, Moderna, Inc. Antibodies Therapeutics in HIV, SARS, Flu, and RSV |
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Michael Z. Lin, Stanford University School of Medicine Short Talk: Short Talk: Design of Oral Antiviral Drugs for Broad-Spectrum Activity Against Coronaviruses |
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Vijayakumar Velu, Emory University Short Talk: Short Talk: IL-15/IL-15Ra Cytokine Therapy Leads to Control of Viral Rebound in SIV Infected Macaques |
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Tomas Raul Wiche Salinas, Emory University Short Talk: Short Talk: Persistent Reduction of SIV Reservoir Through Short-Term BCL-2 Inhibition at ART Initiation in Rhesus Macaques |
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10:00–10:20 AM |
Coffee Break |
Foyer |
12:00–1:00 PM |
Lunch |
Ballroom |
1:00–2:30 PM |
Hands-On Computer Workshop on Los Alamos HIV Sequence and Immunology Databases and Tools (HIV.lanl.gov) |
Auditorium |
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Brian T. Foley, Los Alamos National Lab Los Alamos National Lab |
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Jennifer Mamrosh, Los Alamos National Laboratory Los Alamos National Lab |
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2:30–4:30 PM |
Workshop 2 |
Auditorium |
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Maria C Hesselman, University of Zurich Distinct V2 Apex Broadly Neutralizing Antibody Modalities in Subtype B HIV-1 Infection |
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Doan C. Nguyen, Emory University The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination |
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Sharidan Brown, Scripps Research Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens |
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Enrico Bravo, King's College London IFNα2 Autoantibodies Post SARS-CoV-2 Wave 1 in India Are Associated with Lower Omicron Symptomology |
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Julia Hitschfel, Ragon Institute of MGH, MIT and Harvard Transcriptional Profiling of HIV-Specific CD8 T Cell Responses From Lymph Nodes and Blood of Natural Controllers |
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Nicholas Provine, University of Oxford Immune Signatures Associated with Failure to Seroconvert in Individuals Immunized with MVA-BN as a Vaccine Against MPOX |
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Wilfredo Garcia-Beltran, Ragon Institute of Mass General, MIT and Harvard Evasion of NKG2D-Mediated Cytotoxic Immunity by Sarbecoviruses |
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Adam Zuiani, BioNTech US A Multivalent mRNA Monkeypox Virus Vaccine (BNT166) Protects Mice and Macaques From Orthopoxvirus Disease |
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4:30–5:00 PM |
Coffee Available |
Foyer |
5:00–6:45 PM |
Plenary PM |
Auditorium |
6:45–7:00 PM |
Post-Acute Sequelae of Viral Infections |
Auditorium |
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Nadia R. Roan, University of California, San Francisco Post-Acute Sequelae of COVID-19 |
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Gabriella Worwa, NIH/NIAID/IRF-Frederick Modeling Post-Acute Sequelae of Ebola Virus Disease |
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Irini Sereti, NIAID, National Institutes of Health HIV and Chronic Immune Activation: The Impact of Low Nadir CD4 Counts |
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Till Omansen, Bernhard-Nocht-Institut für Tropenmedizin Short Talk: Short Talk: Lassa Fever is Hallmarked by Inflammation and Kidney Injury or Neurological Disease: Results from the Lassa Fever PATHOGENESIS Study |
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7:00–8:00 PM |
Social Hour with Lite Bites |
Ballroom |