Vector-Pathogen Interactions: From Vector Biology to Innovative Control Strategies (K2)
February 1-4, 2027  | Crowne Plaza Geneva, Geneva, Switzerland
Doug E. Brackney, Flaminia Catteruccia, Utpal Pal and Sarah Merkling
Scholarship Deadline: Oct. 8, 2026 | Abstract Deadline: Jan. 13, 2027 | Early Registration Deadline: Dec. 4, 2026
* Session Chair † Invited but not yet accepted | Program current as of October 25, 2026 7 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, February 1, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, February 2, 2027
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–8:40 AM Welcome Remarks
8:40–9:30 AM Keynote Address
  Erol Fikrig, Yale University School of Medicine
Elucidating Vector-Microbe-Host Interactions using High-Throughput Exoproteome Screens
 
9:30–11:45 AM Mechanistic Insights into Vector Immunity
  Ryan C. Smith, Iowa State University
Mosquito Hemocytes: Double-Edged Swords in Pathogen Control
 
  Shirley Luckhart, University of Idaho
Mosquito Metabolic Regulation of Malaria Parasite Development
 
  Utpal Pal, University of Maryland
Host Signals Promote Tick Immunity and Development
 
  Roenick P Olmo †, Institut de Biologie Moléculaire et Cellulaire - IBMC
Short Talk: Complex I Activity Determines Early Resistance to Dengue Virus Infection in the Mosquito Midgut
 
10:00–10:20 AM Coffee Break
11:55–12:55 PM Workshop: Visual Experimentation
12:55–1:55 PM Lunch
1:00–2:30 PM Poster Session 1
2:30–4:30 PM Symposia Spotlight 1: Vector Determinants of Pathogen Infection
  Anya J O'Neal †, Johns Hopkins Bloomberg School of Public Health
Short Talk: Blood-Induced Hemocytes Manage Oxidative Stress and Facilitate Bacterial Colonization in the Blacklegged Tick Ixodes Scapularis
 
  Thomas Vial †, Institut Pasteur
Short Talk: Cellular and Metabolic Atlases of Aedes aegypti Tissues Reveal an Immunometabolic Switch Associated with Dengue Virus Resistance
 
  Jason L. Rasgon †, Pennsylvania State University
Short Talk: Mosquito Genetic Modification Using Infectious Agents
 
  Lauren Aguado †, Rockefeller University
Short Talk: Revealing Host Factors That Support Alphavirus Replication in Aedes aegypti Mosquito Cells
 
  Yu-Min Chuang †, Yale University
Short Talk: Host Antibodies Targeting Mosquito Proteins Modulate Plasmodium Transmission
 
  Corey L. Campbell †, Colorado State University
Short Talk: Alteration of Histone Modifications and SREBP Transcription Factor Binding Reveal Differences in Mosquito Midgut Responses to Rift Valley Fever Virus Exposure
 
  Joppe Hovius †, Amsterdam UMC
Short Talk: TICK ME: A Novel Human Tick Challenge Model for Dissecting Clinical Manifestations and Immune Signatures of Acquired Tick Resistance
 
  Kevin Maringer †, The Pirbright Institute
Short Talk: The Evolutionary Arms Race Between NF-Κb-Mediated Antiviral Immunity And Orthoflaviviruses Influences Arboviral Vector Tropism and Emergence
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Key Cellular and Molecular Determinants of Arbovirus Infection and Transmission
  Doug E. Brackney, Connecticut Agricultural Experiment Station
How Flaviviruses Initiate Infection of the Mosquito Midgut
 
  Sarah Merkling, Institut Pasteur
Deciphering Mosquito-Virus Interactions at the Single-Cell Level
 
  Gong Cheng, Tsinghua University
A Role for EVs in Mediating Virus-Vector Specificity
 
  Andrii Slonchak †, QIMR Berghofer Medical Research Institute
Spatial Gene Expression Atlas of Aedes Aegypti Reveals Novel Mechanisms of Dengue Virus-Vector Interactions
 
  Erik Turner †, University of California, Davis
Short Talk: Exploring The Potential for Aedes Aegypti Based Environmental Spread a Chikungunya Virus Live Attenuated Vaccine, IXCHIQ
 
7:00–8:00 PM On Own for Dinner
Wednesday, February 3, 2027
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–11:30 AM Cutting-Edge Strategies for Halting Vector-Borne Disease Transmission
  Johanna Fraser, Burnet Institute
Determining the Risk of Virus Resistance Developing against Wolbachia in Aedes Aegypti
 
  Omar S. Akbari, University of California, San Diego
Genetic Biocontrol at Scale: Precision Suppression of Arboviral Vectors
 
  Jeremy K Herren, International Centre of Insect Physiology and Ecology, icipe
Utilizing Microsporidia to Block Malaria Transmission
 
  Sibao Wang, Chinese Academy of Sciences
Harnessing Mosquito Gut Symbiotic Bacteria to Block Malaria Transmission
 
  David Omondi O Ouma †, Liverpool School of Tropical Medicine
Short Talk: Establishing Wolbachia-Based Incompatible Insect Technique for Culex molestus Control in the UK
 
  Chrysoula Kitsou †, University of Maryland
Short Talk: A Feeding-Induced Mouthpart-Associated Protein is a Promising Anti-Tick Vaccine Candidate
 
9:30–9:50 AM Coffee Break
11:40–12:40 PM Panel Discussion 1: From Bench to Field: How to Translate Laboratory Breakthroughs to Actual Control Strategies
12:40–1:40 PM Lunch
1:00–2:30 PM Poster Session 2
2:30–3:30 PM Career Roundtable
3:30–4:30 PM Panel Discussion 2: Global Virus Network (Joint)
4:30–5:00 PM Coffee Available
5:00–7:00 PM Controlling Transmission in Endemic Regions: Field Applications of Novel Control Strategies
  Aboulaye Diabaté, Institut de Recherche en Sciences de la Santé/Centre Muraz, Bobo-Dioulasso
From Entomopathogenic Fungi to Gene Drive: Lessons from the Field
 
  David Malone, Gates Foundation
Precision Vector Control: Rethinking Insecticides for Targeted Transmission Control
 
  Sara N. Mitchell, Debug Project At Google
Wolbachia-Mediated Sterility to Suppress Mosquito Populations
 
  Brian D Foy †, Colorado State University
Short Talk: Current Progress on Medicated Bird Feed to Control Arbovirus Transmission
 
  Vanessa Ngannang †, Centre for Research in Infectious Diseases
Short Talk: The Argininosuccinate Lyase Gene Exacerbates Pyrethroid Resistance in the African Malaria Vector Anopheles funestus Through Cis-Regulatory Elements and Allelic Variation
 
7:00–8:00 PM On Own for Dinner
Thursday, February 4, 2027
7:30–8:30 AM Breakfast
8:30–11:30 AM Vector Physiology: A Key Determinant in Pathogen Transmission
  Laura Dickson, University of Texas of Medical Branch
The Effects of Dehydration and Humidity on Mosquito Susceptibility to Infection
 
  Flaminia Catteruccia, Harvard T.H. Chan School of Public Health
Unraveling Key Mosquito-Parasite Interactions to Block Malaria Transmission
 
  Brian L. Weiss, Yale School of Public Health
An Integral Role for Endosymbiotic Bacteria in Tsetse Fly Biology
 
  Petr Kopacek, Czech Academy of Science
Understanding Tick Biology through Multi-Omics Approaches
 
  Eric Calvo †, NIH
Short Talk: From Enzymes to Scavengers: Functional Evolution of Tsetse Fly Salivary Proteins
 
  Agustin Rolandelli †, INSERM DR Nord Ouest
Short Talk: From Gut to Hemocytes: Tissue-Specific Responses to Blood Feeding and Yersinia pestis Infection in Fleas
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Lunch
2:30–4:30 PM Symposia Spotlight 2: Pathogen Determinants Mediating Vector Infection
  Ailsa Craven †, Harvard T.H. Chan School of Public Health
Short Talk: Unraveling The Role of Plasmodium Falciparum Ookinete Micronemes in Midgut Traversal
 
  Zhong Wan †, Radboudumc
Short Talk: Deep Behavioral Phenotyping of Pathogen Infected Mosquitoes Reveals Species-Specific Behavior Changes Enhancing Transmission
 
  Jason M Park †, Washington State University
Short Talk: Tick specific Anaplasma effector AteA localizes with the actin cytoskeleton and binds cellular signaling proteins Crk and RasGAP
 
  Rhoel R. Dinglasan †, University of Florida
Short Talk: An N-Glycosylation Mutation in the Gc Structural Protein Head Domain of Oropouche Virus (OROV) Is Associated with Transmissible Infection In Mosquitoes
 
  Godfrey Indinda †, The Connecticut Agricultural Experiment Station
An Antiviral Lectin Blocks Orthoflavivirus Infection of Aedes Aegypti Through Nonstructural Protein 1 (NS1) Inhibition
 
  Meghan Hermance †, University of South Alabama
Short Talk: Prior Host Exposure to a Tick-Borne Flavivirus Reshapes the Cutaneous Niche for Viral Co-Feeding Transmission
 
  Alexander Rouvinski †, Hebrew University of Jerusalem, IMRIC
Short Talk: Novel Membrane Fusogens from Insect Restricted Viruses of Negevirus Taxon
 
  Tanwee Das De †, Indian Institute of Science and Education Research
Short Talk: From Odor to Outbreak: Deciphering odor detection mechanisms and Pathogen Transmission
 
4:30–5:00 PM Coffee Available
5:00–6:15 PM Navigating the Vector Landscape: Pathogen Strategies from Infection to Transmission
  Dana K Shaw, Washington State University, College of Veterinary Medicine
The Molecular Tug of War between Tick Immunity and Pathogen Persistence
 
  Jack Sunter, Oxford Brookes University
Sticking Around: Leishmania Adhesion during Sand Fly infection
 
  Brandy St. Laurent †, Cornell University
Short Talk: Malaria Parasite Development in the Invasive Urban Malaria Vector Anopheles Stephensi Under Variable Humidity and Temperature
 
6:15–7:05 PM Closing Keynote Address
  Carolina V. Barillas-Mury, NIAID, National Institutes of Health
The Role of Midgut Stem Cells During Plasmodium Infection of Mosquitoes
 
7:05–7:15 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:15–8:15 PM On Own for Dinner
Friday, February 5, 2027
12:00–11:59 PM Departure