Induced Proximity and Targeted Protein Degradation: Emerging Technologies and Therapeutic Applications (K3)
February 8-11, 2027
| Fairmont Banff Springs, Banff, AB, Canada
Christina Woo, William Forrester and Alessio Ciulli
Scholarship Deadline: Oct. 15, 2026 | Abstract Deadline: Jan. 20, 2027 | Early Registration Deadline: Dec. 11, 2026
| 4:00–8:00 PM |
Registration |
Riverview Lounge |
| 6:00–8:00 PM |
Welcome Mixer |
Riverview Lounge |
Tuesday, February 9, 2027
| 7:00–8:00 AM |
Breakfast |
Alberta/New Brunswick |
| 8:00–8:10 AM |
Welcome Remarks |
Cascade Ballroom |
| 8:10–9:00 AM |
Keynote Address |
Cascade Ballroom |
| |
Brenda A Schulman, Max Planck Institute of Biochemistry
Signaling by the Ubiquitin System |
|
| 9:00–11:30 AM |
Clinic to First Approval, TPD Medicinal Chemistry to in vivo |
Cascade Ballroom |
| |
Angela Cacace, Arvinas Inc
Neurodegenerative Targets in TPD |
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Juliet Williams, Kymera Therapeutics
Bold Approaches to Target Highly Credentialed, Undrugged Disease causing Proteins |
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William Forrester, Novartis
The Novartis Targeted Protein Degradation Platform |
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Gwenn M Hansen, Nurix Therapeutics
Clinical Development of Nurix’s Degrader Drugs |
|
| 9:30–9:50 AM |
Coffee Break |
Riverview Lounge |
| 11:40–12:40 PM |
Meet the Editors (Joint) |
Cascade Ballroom |
| 12:40–1:00 PM |
Poster Setup |
Alberta/New Brunswick |
| 12:40–2:30 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Alberta/New Brunswick |
| 2:30–4:30 PM |
Symposia Spotlight 1 |
Cascade Ballroom |
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
Riverview Lounge |
| 5:00–7:00 PM |
Induced Proximity Modalities to Treat Human Disease |
Cascade Ballroom |
| |
Lauren V Albrecht, University of California Irvine
Methyl Arginine TACs |
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Steven Banik, Stanford University
Shuttle Proteins |
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Mikko Taipale, University of Toronto
Pervasive Mislocalization of Pathogenic Coding Variants Underlying Human Disorders: Cell |
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Short Talk(s) Chosen from Abstracts
|
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| 7:00–8:00 PM |
Social Hour with Dinner |
Alberta/New Brunswick |
| 7:30–10:00 PM |
Poster Session 1 |
Alberta/New Brunswick |
Wednesday, February 10, 2027
| 7:00–8:00 AM |
Breakfast |
Alberta/New Brunswick |
| 8:00–11:00 AM |
New Frontiers for E3 Ligases in TPD |
Cascade Ballroom |
| |
Nicolas H Thomä, EPFL Lausanne
Haven't Got a Glue: Protein Surface Variation for the Design of Molecular Glue Degraders |
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Lindsey Ingerman James, University of North Carolina at Chapel Hill
E3 Ligase and Degrader Discovery |
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Jacob E Corn, ETH Zürich
Recognition and Removal of Proteins with Weird Stuff Attached to Them |
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| |
Christina Woo, Harvard University
Probing Cereblon Allosterically |
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Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
Riverview Lounge |
| 11:10–12:10 PM |
Panel Discussion: How to Start a Company |
Cascade Ballroom |
| 12:10–1:00 PM |
Poster Setup |
Alberta/New Brunswick |
| 12:10–3:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Alberta/New Brunswick |
| 3:00–4:30 PM |
Career Roundtable (Joint) |
Alhambra Ballroom |
| 4:30–5:00 PM |
Coffee Available |
Riverview Lounge |
| 5:00–7:00 PM |
Discovery Chemistry for Novel Induced Proximity Modalities |
Cascade Ballroom |
| |
Alessio Ciulli, University of Dundee, School of Life Sciences
Trivalent TAC Chemistry |
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Nir London, Weizmann Institute of Science
A Pharmacological Modality to Sequester Homomeric Proteins |
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Roman C Sarott, Max Planck Institute for Medical Research
Gene Reprogramming via Chemical Induced Proximity |
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Short Talk(s) Chosen from Abstracts
|
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| 7:00–8:00 PM |
Social Hour with Dinner |
Alberta/New Brunswick |
| 7:30–10:00 PM |
Poster Session 2 |
Alberta/New Brunswick |
Thursday, February 11, 2027
| 7:00–8:00 AM |
Breakfast |
Alberta/New Brunswick |
| 8:00–11:00 AM |
Induced Proximity Biologics from the Lab to the Clinic |
Cascade Ballroom |
| |
Laura L. Kiessling, Massachusetts Institute of Technology
Cell Surface Induced Proximity Engineering |
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Hui-Kuan Lin, Duke University
Degrader Delivery through CD36 |
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John Flygare, Eli Lilly
Delving into Novel Design and Development to Strive for Next-Generation ADCs Providing Long-Term Benefit to Patients |
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Xin Zhou, Dana-Farber Cancer Institute
Programmable Proteins to Redirect Cell Fate |
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Short Talk(s) Chosen from Abstracts
|
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| 9:00–9:20 AM |
Coffee Break |
Riverview Lounge |
| 11:00–2:30 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2 |
Cascade Ballroom |
| |
Short Talks Chosen from Abstracts
|
|
| 4:30–5:00 PM |
Coffee Available |
Riverview Lounge |
| 5:00–6:15 PM |
Glues at the AI and ML Interface |
Cascade Ballroom |
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Victor Guallar, Barcelona Supercomputing Center and Nostrum Biodiscovery
There Is More Than One Ligase and Molecular Glue for Each Target... & We Know Them |
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Short Talk(s) Chosen from Abstracts
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| 6:15–7:05 PM |
Closing Keynote Address |
Cascade Ballroom |
| |
Gerald R. Crabtree, Stanford University
Past and Future of Chemical Induced Proximity |
|
| 7:05–7:15 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Cascade Ballroom |
| 7:15–8:15 PM |
Social Hour with Dinner |
Alberta/New Brunswick |
| 8:00–11:00 PM |
Entertainment |
|
Friday, February 12, 2027
