Autophagy in Health and Disease: From Mechanisms to Therapeutics (K4)
February 8-11, 2027  | Fairmont Banff Springs, Banff, AB, Canada
Hong Zhang, Susan Ferro-Novick and Hitoshi Nakatogawa
Scholarship Deadline: Oct. 15, 2026 | Abstract Deadline: Jan. 20, 2027 | Early Registration Deadline: Dec. 11, 2026
* Session Chair † Invited but not yet accepted | Program current as of August 5, 2026 11 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, February 8, 2027
4:00–8:00 PM Registration Riverview Lounge
6:00–8:00 PM Welcome Mixer Riverview Lounge
Tuesday, February 9, 2027
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–8:10 AM Welcome Remarks Alhambra Ballroom
8:10–9:00 AM Keynote Address Alhambra Ballroom
  Noboru Mizushima, University of Tokyo
Machinery for Autophagosome Formation and Maturation
 
9:00–11:15 AM Autophagy Machinery and Regulation Alhambra Ballroom
  Hitoshi Nakatogawa, Tokyo Institute of Technology
Mechanism of ER-IM Contact Formation
 
  Sascha Martens, University of Vienna
In vitro Reconstitution of Autophagy
 
  Nobuo N Noda, Hokkaido University
Lipid Transport in Autophagosome Formation
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break Riverview Lounge
11:40–12:40 PM Meet the Editors (Joint) Cascade Ballroom
12:40–1:00 PM Poster Setup Alberta/New Brunswick
12:40–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Alberta/New Brunswick
2:30–4:30 PM Symposia Spotlight 1: Mechanistic Insights into Cargo-Specific Autophagy Alhambra Ballroom
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–7:00 PM Mechanistic Insights into Cargo-Specific Autophagy Alhambra Ballroom
  Susan Ferro-Novick, University of California, San Diego
Autophagy Receptors Function at Distinct ER Domains
 
  Florian Wilfling, Max-Planck-Institut of Biophysics
Structural Insights into Protein Aggregates Degraded by Autophagy
 
  Eric H. Baehrecke, University of Massachusetts Medical School
Macroautophagy-Independent Clearance of Mitochondria
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
7:30–10:00 PM Poster Session 1 Alberta/New Brunswick
Wednesday, February 10, 2027
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–11:00 AM Autophagy in Cellular and Organismal Physiology Alhambra Ballroom
  Ana Maria Cuervo, Albert Einstein College of Medicine
Chaperone-Mediated Autophagy in Metabolism
 
  Hong Zhang, Chinese Academy of Sciences
Systemic Regulation of Autophagy in C. Elegans
 
  Xiaochen Wang, Southern University of Science and Technology
Lysosome Dynamics: Regulation and Functions
 
  Roberto Zoncu, University of California Berkeley
Lysosomes in Integrating Biosynthetic and Catabolic Processes
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break Riverview Lounge
11:10–12:10 PM Panel Discussion: Big Picture Topics Alhambra Ballroom
12:10–1:00 PM Poster Setup Alberta/New Brunswick
12:10–3:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Alberta/New Brunswick
3:00–4:30 PM Career Roundtable (Joint) Alhambra Ballroom
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–7:00 PM Beyond Degradation: Novel Autophagy-Related Pathways Alhambra Ballroom
  Vojo Deretic, University of New Mexico Health Sciences Center
Noncanonical Roles of Atg8ylation in Membrane Dynamics
 
  Yan Zhao, Southern University of Science and Technology
Autophagy Proteins Hijacked by Coronaviruses
 
  Mondira Kundu, St. Jude Children's Hospital
ULK1/2 Physiological Functions
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
7:30–10:00 PM Poster Session 2 Alberta/New Brunswick
Thursday, February 11, 2027
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–11:00 AM Autophagic Dysfunction in Disease Alhambra Ballroom
  Dimitri Krainc, Northwestern University
Lysosomal Function and Parkinson’s Disease
 
  Patricia Boya, University of Fribourg
Autophagy and Lysosomes in Aging and Age-Related Diseases
 
  Ai Yamamoto, Columbia University
Autophagy Dysfunction and Neurodegeneration
 
  Anna Katharina Simon, Max-Delbrück-Centrum für Molekulare Medizin (MDC)
Autophagy in T Cell Aging
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break Riverview Lounge
11:00–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Beyond Degradation: Novel Function of Autophagy Proteins Alhambra Ballroom
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–6:45 PM Therapeutic Innovations: Harnessing Autophagy for Treatment Alhambra Ballroom
  Boxun Lu, Fudan University
Molecular Glues for Targeted Mutant HTT Autophagic Degradation
 
  Speaker to be Announced
 
  Vassiliki Nikoletopoulou, University of Lausanne
Mechanisms of Autophagy-Dependent Secretion in Neurons
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions Alhambra Ballroom
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Friday, February 12, 2027
12:00–11:59 PM Departure