Autophagy in Health and Disease: From Mechanisms to Therapeutics (K4)
February 8-11, 2027
| Fairmont Banff Springs, Banff, AB, Canada
Hong Zhang, Susan Ferro-Novick and Hitoshi Nakatogawa
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Tuesday, February 9, 2027
| 8:00–9:00 AM |
Welcome and Keynote Address |
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Noboru Mizushima, University of Tokyo
Machinery for Autophagosome Formation and Maturation |
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| 9:00–11:15 AM |
Autophagy Machinery and Regulation |
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Hitoshi Nakatogawa, Tokyo Institute of Technology
Mechanism of ER-IM Contact Formation |
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Claudine Kraft †, University of Freiburg
Phase Separation in Assembly of Autophagic Initiation Hubs on Cargo |
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Nobuo N Noda, Hokkaido University
Lipid Transport in Autophagosome Formation |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–12:15 PM |
Meet the Editors |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Mechanistic Insights into Cargo-Specific Autophagy |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Mechanistic Insights into Cargo-Specific Autophagy |
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Susan Ferro-Novick, University of California, San Diego
Autophagy Receptors Function at Distinct ER Domains |
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Florian Wilfling †, Max-Planck-Institut of Biophysics
Structural Insights into Protein Aggregates Degraded by Autophagy |
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Eric H. Baehrecke, University of Massachusetts Medical School
Macroautophagy-Independent Clearance of Mitochondria |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, February 10, 2027
| 8:00–11:00 AM |
Autophagy in Cellular and Organismal Physiology |
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Ana Maria Cuervo, Albert Einstein College of Medicine
Chaperone-Mediated Autophagy in Metabolism |
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Hong Zhang, Chinese Academy of Sciences
Systemic Regulation of Autophagy in C. Elegans |
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Xiaochen Wang, Southern University of Science and Technology
Lysosome Dynamics: Regulation and Functions |
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Roberto Zoncu, University of California Berkeley
Lysosomes in Integrating Biosynthetic and Catabolic Processes |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion: Big Picture Topics |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Beyond Degradation: Novel Autophagy-Related Pathways |
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Vojo Deretic †, University of New Mexico Health Sciences Center
Noncanonical Roles of Atg8ylation in Membrane Dynamics |
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Yan Zhao, Southern University of Science and Technology
Autophagy Proteins Hijacked by Coronaviruses |
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Mondira Kundu, St. Jude Children's Hospital
ULK1/2 Physiological Functions |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Thursday, February 11, 2027
| 8:00–11:00 AM |
Autophagic Dysfunction in Disease |
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Dimitri Krainc, Northwestern University
Lysosomal Function and Parkinson’s Disease |
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Noor Gammoh †, The University of Edinburgh
Autophagy in Tumor Formation |
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Patricia Boya †, University of Fribourg
Autophagy and Lysosomes in Aging and Age-Related Diseases |
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Boxun Lu, Fudan University
Molecular Glues for Targeted Mutant HTT Autophagic Degradation |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Beyond Degradation: Novel Function of Autophagy Proteins |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Therapeutic Innovations: Harnessing Autophagy for Treatment |
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Gilbert Di Paolo †, Denali Therapeutics Inc.
Harnessing Lipids in Neurodegenerative Diseases |
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Mary E. Hamby †, Cognition Therapeutics, Inc.
Pharmacological Targeting of the Alzheimer's Disease |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Friday, February 12, 2027
