Proximity Based Biology and Therapeutics: Targeted Protein Degradation and Beyond (K6)
February 23-26, 2026
| Fairmont Banff Springs, Banff, AB, Canada
Neil Bence, Cheryl Arrowsmith and Amit Choudhary
Scholarship Deadline: Oct. 29, 2025 | Abstract Deadline: Feb. 3, 2026 | Early Registration Deadline: Dec. 30, 2025
Monday, February 23, 2026
| 4:00–8:00 PM |
Registration |
Van Horne Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
Van Horne Foyer |
Tuesday, February 24, 2026
| 7:00–8:00 AM |
Breakfast |
President's Hall |
| 8:00–9:00 AM |
Welcome and Keynote Address |
Van Horne A |
| |
Ning Zheng, University of Washington
Stuck on You: The Omnipresence of Molecular Glues |
|
| 9:00–11:15 AM |
Transformation of Drug Discovery and Induced Proximity through AI/ML |
Van Horne A |
| |
Nicholas F. Polizzi, Dana-Farber Cancer Institute
Designing Biosensors from Scratch Using Principles of Induced Proximity |
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George M Burslem †, University of Pennsylvania
Talk Title to be Announced |
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Mikko Taipale †, University of Toronto
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
Van Horne Foyer |
| 11:15–1:00 PM |
Poster Setup |
Van Horne C |
| 11:15–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Van Horne C |
| 2:30–4:30 PM |
Symposia Spotlight: Emerging Technologies and Approaches in Proximity Induction |
Van Horne A |
| 4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
| 5:00–7:00 PM |
Novel Induced Proximity based Approaches |
Van Horne A |
| |
Amit Choudhary, Harvard Medical School
Proximity-Inducing Molecules for Protein Editing |
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Gerald R. Crabtree, Stanford University
Transcriptional Chemical Inducers of Proximity |
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| |
Elena De Vita, Queen Mary University of London
Targeted Protein Dephosphorylation vial PHOSTACs |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
President's Hall |
| 7:30–10:00 PM |
Posters |
Van Horne C |
Wednesday, February 25, 2026
| 7:00–8:00 AM |
Breakfast |
President's Hall |
| 8:00–11:00 AM |
Leveraging Novel Protein Degradation Machinery for Next Generation Protein Degraders |
Van Horne A |
| |
Cheryl Arrowsmith, University of Toronto
Increasing the Repertoire of Chemically Recruitable E3 Ligases for Targeted Protein Degradation |
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| |
Asad Taherbhoy, Foghorn Therapeutics
Novel Strategies of Targeting the Transcriptional Machinery for Degradation |
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| |
Gwenn Hansen, Nurix Therapeutics
Enabling Novel Ligases for Targeted Protein Degradation through DEL based Approaches |
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| |
Daniel K Nomura, University of California, Berkeley
Enabling Novel Ligases |
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| |
Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
Van Horne Foyer |
| 11:00–1:00 PM |
Poster Setup |
Van Horne C |
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Van Horne C |
| 3:00–4:30 PM |
Career Roundtable |
Van Horne B |
| 4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
| 5:00–7:00 PM |
Induced Proximity to Modulate Protein Complexes |
Van Horne A |
| |
Katherine Kayser-Bricker, Halda Therapeutics
Regulated Induced Proximity Targeting Chimeras (RIPTACs) |
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Michelle R. Arkin, University of California, San Francisco
Utilization of Stabilizers of Protein-Protein Interactions |
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Jian Jin, Icahn School of Medicine at Mount Sinai
New Approaches to Target Undruggable Proteins |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
President's Hall |
| 7:30–10:00 PM |
Posters |
Van Horne C |
Thursday, February 26, 2026
| 7:00–8:00 AM |
Breakfast |
President's Hall |
| 8:00–11:00 AM |
Clinical Progress in Induced Proximity Approaches |
Van Horne A |
| |
Neil Bence, Bristol Myers Squibb
BMS Protein Degrader from Discovery to Clinical Development |
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| |
Paula O’Connor, Nurix Therapeutics
Advancing Novel Degraders to the Clinic (BTK and Beyond) |
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| |
Michael Feldman †, Kymera Therapeutics
STAT6 Degraders for Autoimmune Disease |
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| |
Sheryl Gough, Arvinas Inc
The PROTAC Mode of Action Makes Therapeutic Targeting of BCL6 Possible |
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Short Talk(s) Chosen from Abstracts
|
|
| 9:00–9:20 AM |
Coffee Break |
Van Horne Foyer |
| 11:00–5:00 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Panel Discussion: Driving Innovation: From Concept to Company, how to Start a Company around a New Idea |
Van Horne A |
| 4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
| 5:00–6:45 PM |
Enabling Discovery and Development of Novel Induced Proximity Molecules and Glues |
Van Horne A |
| |
Georg E. Winter, CeMM Research Center for Molecular Medicine
Novel Glue Discovery via Isogenic Morphological Profiling |
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Alessio Ciulli, University of Dundee, School of Life Sciences
Expanding the Target Space of Protein Degraders |
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Lauren V Albrecht †, University of California Irvine
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
Van Horne A |
| 7:00–8:00 PM |
Social Hour with Dinner |
President's Hall |
| 8:00–11:00 PM |
Entertainment |
|
Friday, February 27, 2026
