Hematopoiesis (K7)
February 23-26, 2026
| Keystone Resort, Keystone, CO, United States
Vijay G. Sankaran, Anna E. Beaudin and Esther Obeng
Scholarship Deadline: Oct. 30, 2025 | Abstract Deadline: Feb. 4, 2026 | Early Registration Deadline: Dec. 31, 2025
Monday, February 23, 2026
| 4:00–8:00 PM |
Registration |
Longs Peak Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
Longs Peak Foyer |
Tuesday, February 24, 2026
| 7:00–8:00 AM |
Breakfast |
Quandary Peak |
| 8:00–8:10 AM |
Welcome Remarks |
Grays Peak |
| 8:10–9:00 AM |
Keynote Address |
Grays Peak |
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* Anna E. Beaudin, University of Utah School of Medicine
Session Chair |
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Margaret A Goodell, Baylor College of Medicine
Mosaicism in Hematopoiesis |
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| 9:00–11:15 AM |
Developmental Hematopoiesis |
Grays Peak |
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Leonard I. Zon, HHMI/Boston Children's Hospital
Zebrafish Developmental Hematopoiesis |
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* Anna E. Beaudin, University of Utah School of Medicine
Developmental Hematopoiesis |
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Anne H Carroll, Albert Einstein College of Medicine
Short Talk: Spatiotemporal and Molecular Regulation of Embryonic Lymphoid Progenitor Production |
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Stefan Radtke, Fred Hutchinson Cancer Center
Short Talk: CD90 – More Than just a Stem Cell Marker: Implication for Blood Development, Cancer Immunotherapy, and Gene Therapy |
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| 9:30–9:50 AM |
Coffee Break |
Longs Peak Foyer |
| 9:50–9:55 AM |
Award Recipient Acknowledgement |
Grays Peak |
| 11:15–12:15 PM |
Meet the Editors |
Grays Peak |
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Esther Obeng, Emory University School of Medicine
*Session Chair, Blood Editorial Board |
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Gaia Trincucci, Journal of Experimental Medicine
Deputy Editor, JEM |
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Margaret A Goodell, Baylor College of Medicine
Editorial Board, Cell Stem Cell & Cancer Cell |
|
| 12:15–1:00 PM |
Poster Setup |
Quandary Peak |
| 12:15–2:30 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
Quandary Peak |
| 2:30–4:30 PM |
Symposia Spotlight 1 |
Grays Peak |
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* Esther Obeng, Emory University School of Medicine
Session Chair |
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Jonathan S. Weissman, Whitehead Institute, HHMI, and MIT
Long Talk: Lineage Tracing of Native Hematopoiesis |
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Cecilia Cotta-Ramusino, Tessera Therapeutics
Long Talk: In Vivo Genome Engineering of HSCs in Sickle Cell Disease |
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Yoon-A Kang, Washington University in St. Louis
Unfolded Protein Response Signaling Promotes Myeloid Cell Production and Cooperates with Oncogenic Mutation |
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Alan B. Cantor, Boston Children's Hospital/Dana-Farber Cancer Institute, Harvard Medical School
Megakaryocyte p53 activation in ANKRD26-Related Thrombocytopenia and Leukemia Predisposition |
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Morgan Walcheck, Boston Children's Hospital
Stress-responsive Embryonic HSC Fate is Balanced via the AHR-NLRP3 Inflammasome Axis |
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Nikita A Vantsev, University of Pennsylvania
PITPβ Drives Jak2V617F-mediated Myeloproliferative Neoplasms in Mice Through AKT Activation |
|
| 4:30–5:00 PM |
Coffee Available |
Longs Peak Foyer |
| 5:00–7:00 PM |
Hematopoietic Stem Cell Biology |
Grays Peak |
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* Robert A.J. Signer, University of California, San Diego
HSC Regulation by the Proteostasis Network |
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Shalin H. Naik, Walter & Eliza Hall Institute
Clonal Dynamics of HSC Contributions to Hematopoiesis |
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Raffaella Di Micco, Ospedale San Raffaele
Stress Responses in HSCs |
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Victoria Lawless, Weill Cornell Medicine
Short Talk: An IFN-gamma-Mediated Adaptive Immune Signaling Axis in Bone Marrow Reprograms Hematopoietic Stem Cells to Improve Myeloid Function |
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Lea Flippe, Murdoch Children's Research Institut
Short Talk: MECOM Expression Tracks Haematopoietic Development from Artery to Engraftable iHSCs |
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| 7:00–8:00 PM |
Social Hour with Dinner |
Quandary Peak |
| 7:30–10:00 PM |
Poster Session 1 |
Quandary Peak |
Wednesday, February 25, 2026
| 7:00–8:00 AM |
Breakfast |
Quandary Peak |
| 8:00–11:00 AM |
Hematopoietic Microenvironment |
Grays Peak |
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* Kellie Machlus, Boston Children's Hospital and Harvard Medical School
Session Chair |
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Daniel Lucas, Cincinnati Children's Medical Center
Imaging of the Bone Marrow Spatial Architecture |
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Louise E Purton, St. Vincent's Institute of Medical Research
Regulation of Hematopoiesis and Bone Marrow Failure Syndromes by Dysregulated Endothelial Cells |
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Rebekka Schneider, Erasmus MC
MPN Microenvironment |
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Sean J. Morrison, University of Texas Southwestern Medical Center
Niche Regulation of HSCs |
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Christina M Termini, Fred Hutchinson Cancer Center
Short Talk: Depletion of Microenvironmental Syndecan-2 Impairs Hematopoietic Stem Cell Self-Renewal and Cytokine Responses |
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Bo Shen, Tsinghua University
Short Talk: Mammalian Bone Marrow Adipocytes Fuel Hematopoietic Maintenance and Regeneration |
|
| 9:00–9:20 AM |
Coffee Break |
Longs Peak Foyer |
| 11:00–1:00 PM |
Poster Setup |
Quandary Peak |
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Quandary Peak |
| 1:30–2:45 PM |
Career Roundtable (Joint) |
Longs Peak |
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Lidia Bosurgi, University Medical Center Hamburg-Eppendorf
Group Leader, Professor |
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Dale Starkie, DJS Antibodies - AbbVie
Director |
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Christina M Termini, Fred Hutchinson Cancer Center
Assistant Professor |
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Stella J Berendam, Astrazeneca
Discovery Safety Science Specialist, Immunotoxicology |
|
| 4:30–5:00 PM |
Coffee Available |
Longs Peak Foyer |
| 5:00–7:00 PM |
Aging, Inflammation, and Disease |
Grays Peak |
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* Amelie Collins, Cincinnati Children's Hospital Medical Center
Session Chair |
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Jennifer Trowbridge, The Jackson Laboratory
Selective Advantage and Selective Vulnerability in Clonal Hematopoiesis |
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Luis Batista, Huntsman Cancer Institute, University of Utah
Impaired Post-transcriptional Processing of ncRNAs Trigger Hematopoietic Failure |
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Vijay G. Sankaran, Boston Children’s Hospital
Insights from Blood Disorders Enable New Therapies |
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Julia Belk, Stanford
Short Talk: Clonal Hematopoiesis and the Aging Brain |
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Nader Yatim, Icahn School of Medicine at Mount Sinai
Short Talk: Impaired Polyamine Metabolism Drives Hematopoietic Aging |
|
| 7:00–8:00 PM |
Social Hour with Dinner |
Quandary Peak |
| 7:30–10:00 PM |
Poster Session 2 |
Quandary Peak |
Thursday, February 26, 2026
| 7:00–8:00 AM |
Breakfast |
Quandary Peak |
| 8:00–11:00 AM |
Cutting Edge Innovations in Hematopoiesis |
Grays Peak |
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* Weike Pei, Westlake University
Session Chair |
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Vanessa M Scanlon, UConn Health
Remote Presentation: Consequences of Erythropoietin Signaling in Megakaryocytic-Erythroid Progenitors |
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Britta Will, Albert Einstein College of Medicine
Metabolic Regulation of HSCs |
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Sara Tomei, Walter and Eliza Institute Hall of Medical Research
Short Talk: Clonal Multi-omics Uncovers CD200 as a Marker for Bona Fide HSCs |
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Anna-Lena Neehus, Boston Children's Hospital
Short Talk: Stalled B Cell Development as a Convergent Mechanism for Germline Predisposition to Childhood Leukemia |
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Arushana A Maknojia, Baylor College of Medicine
Short Talk: An Unusual Friendship: How Gut Microbiota and Endogenous Retroviruses (ERVs) Interact to Support Hematopoiesis? |
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Amanda J Daniels, University of California - San Diego
Short Talk: Enhancing Translation Fidelity Confers Hematopoietic Stem Cells with Increased Resistance to Stress and Suppresses Cancer Initiation |
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Peter Kurre, University of Pennsylvania
Short Talk: MYC as a Central Player in Fanconi Anemia Associated Hematopoiesis Failure |
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Teng Gao, Boston Children's Hospital
Short Talk: Robust Single-Cell Multiomic Lineage Tracing of Human Hematopoiesis Enabled by Population-Genetic Modeling of Mitochondrial DNA Drift |
|
| 9:00–9:20 AM |
Coffee Break |
Longs Peak Foyer |
| 11:00–5:00 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2 |
Grays Peak |
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* Jennifer Trowbridge, The Jackson Laboratory
Session Chair |
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Bianca E Bean, University of Florida
Netrin-1 Regulates Hematopoietic Stem Cell Function via UNC5A |
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Michalis Agathocleous, University of Texas Southwestern Medical Center
Stem Cell Function and Hematopoiesis in the Absence of Carbohydrate Oxidation and Fermentation |
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Shinya Fujita, National Institute of Global Health and Medicine, Japan Institute for Health Security
Piezo1 Mechanosensing as a Druggable Target to Enhance Hematopoietic Stem Cell Homing to Bone Marrow |
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Chia-Jo Chen, Cincinnati Children's Hospital Medical Center
Asynchronous Acquisition of Hematopoietic Stem Cell Functional Maturity During Postnatal Development |
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Sulagna Sanyal, University of Pennsylvania
YY1 Depletion Reprograms Committed Murine Pro-B Cells to Acquire Hematopoietic Stem Cell Properties |
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Jill Henrich, University of Pennsylvania
Regulation of Ribosomal RNA Transcription by MYC in Hematopoiesis |
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James Swann, Columbia University
Molecular Cartography of Emergency Myelopoiesis Reveals Conserved Modules of Hematopoietic Activation in Inflammation and Leukemia |
|
| 4:30–5:00 PM |
Coffee Available |
Longs Peak Foyer |
| 5:00–6:45 PM |
Hematologic Malignancies |
Grays Peak |
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* Michael G Kharas, Memorial Sloan Kettering Cancer Center
Session Chair |
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Catriona H.M. Jamieson, University of California, San Diego
Myeloid Malignancies |
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Esther Obeng, Emory University School of Medicine
Pathogenesis of MDS |
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John E. Dick, Princess Margaret Cancer Centre
What Makes a Stem Cell a Stem Cell and How Does It Go Bad |
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Yuanyuan Wang, UCLA
Short Talk: Unraveling Stemness Mechanisms in MECOM Rearranged Acute Myeloid Leukemias |
|
| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
Grays Peak |
| 7:00–8:00 PM |
Social Hour with Dinner |
Quandary Peak |
| 8:00–9:00 PM |
Cash Bar |
Quandary Peak |
| 8:00–9:00 PM |
Entertainment |
Quandary Peak |
Friday, February 27, 2026
