Hematopoiesis (K7)
February 23-26, 2026  | Keystone Resort, Keystone, CO, United States
Vijay G. Sankaran, Anna E. Beaudin and Esther Obeng
Scholarship Deadline: Oct. 30, 2025 | Abstract Deadline: Feb. 4, 2026 | Early Registration Deadline: Dec. 31, 2025
* Session Chair † Invited but not yet accepted | Program current as of November 25, 2025 10 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Monday, February 23, 2026
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Tuesday, February 24, 2026
7:00–8:00 AM Breakfast
8:00–8:10 AM Welcome Remarks
8:10–9:00 AM Keynote Address
  Margaret A Goodell, Baylor College of Medicine
Mosaicism in Hematopoiesis
 
9:00–11:15 AM Developmental Hematopoiesis
  Muzlifah A Haniffa, Wellcome Sanger Institute
Human Developmental Hematopoiesis
 
  Leonard I. Zon, HHMI/Boston Children's Hospital
Zebrafish Developmental Hematopoiesis
 
  Anna E. Beaudin, University of Utah School of Medicine
Developmental Hematopoiesis
 
  Anne H Carroll †, Albert Einstein College of Medicine
Short Talk: Spatiotemporal and Molecular Regulation of Embryonic Lymphoid Progenitor Production
 
9:30–9:50 AM Coffee Break
11:15–12:15 PM Meet the Editors
12:15–1:00 PM Poster Setup
12:15–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1
  Yoon-A Kang †, Washington University in St. Louis
Unfolded Protein Response Signaling Promotes Myeloid Cell Production and Cooperates with Oncogenic Mutation
 
  Stefan Radtke †, Fred Hutchinson Cancer Center
CD90 – More Than just a Stem Cell Marker: Implication for Blood Development, Cancer Immunotherapy, and Gene Therapy
 
  Benjamin L. Ebert, Dana-Farber Cancer Institute
Clonal Hematopoiesis
 
  Dan A. Landau, Weill Cornell Medicine
Single Cell Biology of Hematologic Malignancies
 
  Arushana A Maknojia †, Baylor College of Medicine
An Unusual Friendship: How Gut Microbiota and Endogenous Retroviruses (ERVs) Interact to Support Hematopoiesis?
 
  Peter Kurre †, University of Pennsylvania
MYC as a Central Rheostat in Fanconi Anemia Associated Hematopoiesis Failure
 
  Alan B. Cantor †, Boston Children's Hospital/Dana-Farber Cancer Institute, Harvard Medical School
Megakaryocyte p53 activation in ANKRD26-Related Thrombocytopenia and Leukemia Predisposition
 
  Amanda J Daniels †, University of California - San Diego
Enhancing Translation Fidelity Confers Hematopoietic Stem Cells with Increased Resistance to Stress and Suppresses Cancer Initiation
 
  Morgan Walcheck †, Boston Children's Hospital
Stress-responsive Embryonic HSC Fate is Balanced via the AHR-NLRP3 Inflammasome Axis
 
  Nikita A Vantsev †, University of Pennsylvania
PITPβ is Required for Malignant pAKT Activation and the Development of Jak2 V617F-Induced Myeloproliferative Neoplasms (MPN) in Mice
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Hematopoietic Stem Cell Biology
  Shalin H. Naik, Walter & Eliza Hall Institute
Clonal Dynamics of HSC Contributions to Hematopoiesis
 
  Raffaella Di Micco, Ospedale San Raffaele
Stress Responses in HSCs
 
  Britta Will, Albert Einstein College of Medicine
Metabolic Regulation of HSCs
 
  Victoria Lawless †, Weill Cornell Medicine
Short Talk: An IFN-gamma-Mediated Adaptive Immune Signaling Axis in Bone Marrow Reprograms Hematopoietic Stem Cells to Improve Myeloid Function
 
  Lea Flippe †, Murdoch Children's Research Institut
Short Talk: MECOM Expression Tracks Haematopoietic Development from Artery to Engraftable iHSCs
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Poster Session 1
Wednesday, February 25, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Hematopoietic Microenvironment
  Daniel Lucas, Cincinnati Children's Medical Center
Imaging of the Bone Marrow Spatial Architecture
 
  Louise E. Purton, St. Vincent's Institute of Medical Research
Regulation of Hematopoiesis and Bone Marrow Failure Syndromes by Dysregulated Endothelial Cells
 
  Rebekka Schneider, Erasmus MC
MPN Microenvironment
 
  Sean J. Morrison, University of Texas Southwestern Medical Center
Niche Regulation of HSCs
 
  Christina Marie Termini †, Fred Hutchinson Cancer Center
Short Talk: Depletion of Microenvironmental Syndecan-2 Impairs Hematopoietic Stem Cell Self-Renewal and Cytokine Responses
 
  Bo Shen †, Tsinghua University
Short Talk: Mammalian Bone Marrow Adipocytes Fuel Hematopoietic Maintenance and Regeneration
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
1:45–2:45 PM Career Roundtable (Joint)
3:00–4:30 PM Grant Writing Workshop
4:30–5:00 PM Coffee Available
5:00–7:00 PM Aging, Inflammation, and Disease
  Jennifer Trowbridge, The Jackson Laboratory
Inflammatory Cytokines in Clonal Hematopoiesis
 
  Luis Batista, Washington University School of Medicine
Telomere Disorders and Hematopoiesis
 
  Vijay G. Sankaran, Boston Children’s Hospital
Insights from Blood Disorders Enable New Therapies
 
  Julia Belk †, Stanford
Short Talk: Clonal Hematopoiesis and the Aging Brain
 
  Nader Yatim †, Icahn School of Medicine at Mount Sinai
Short Talk: Impaired Polyamine Metabolism Drives Hematopoietic Aging
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Poster Session 2
Thursday, February 26, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Cutting Edge Innovations in Hematopoiesis
  Jonathan S. Weissman, Whitehead Institute, HHMI, and MIT
Lineage Tracing of Native Hematopoiesis
 
  Vanessa M Scanlon, UConn Health
Extrinsic Regulators of Hematopoietic Progenitor Commitment
 
  Robert A.J. Signer, University of California, San Diego
HSC Regulation by the Proteostasis Network
 
  Cecilia Cotta-Ramusino, Tessera Therapeutics
In Vivo Genome Engineering of HSCs in Sickle Cell Disease
 
  Sara Tomei †, Walter and Eliza Institute Hall of Medical Research
Short Talk: Clonal Multi-omics Uncovers CD200 as a Marker for Bona Fide HSCs
 
  Anna-Lena Neehus †, Boston Children's Hospital
Short Talk: Stalled B Cell Development as a Convergent Mechanism for Germline Predisposition to Childhood Leukemia
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2
  Bianca E Bean †, University of Florida
Netrin-1 Regulates Hematopoietic Stem Cell Function via UNC5A
 
  Michalis Agathocleous †, University of Texas Southwestern Medical Center
Stem Cell Function and Hematopoiesis in the Absence of Carbohydrate Oxidation and Fermentation
 
  Shinya Fujita †, Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security
Piezo1 Mechanosensing as a Druggable Target to Enhance Hematopoietic Stem Cell Homing to Bone Marrow
 
  Chia-Jo Chen †, Cincinnati Children's Hospital Medical Center
Asynchronous Acquisition of Hematopoietic Stem Cell Functional Maturity During Postnatal Development
 
  Sulagna Sanyal †, University of Pennsylvania
YY1 Depletion Reprograms Committed Murine Pro-B Cells to Acquire Hematopoietic Stem Cell Properties
 
  Jiazhuo Li †, South China University of Technology
PRC2 Times Sequential Metabolic–Autophagy Transitions to Coordinate Terminal Erythropoiesis
 
  Jill Henrich †, University of Pennsylvania
Regulation of Ribosomal RNA Transcription by MYC in Hematopoiesis
 
  James Swann †, Columbia University
Molecular Cartography of Emergency Myelopoiesis Reveals Conserved Modules of Hematopoietic Activation in Inflammation and Leukemia
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Hematologic Malignancies
  Catriona H.M. Jamieson, University of California, San Diego
Myeloid Malignancies
 
  Esther Obeng, St. Jude Children's Research Hospital
Pathogenesis of MDS
 
  John E. Dick, Princess Margaret Cancer Centre
What Makes a Stem Cell a Stem Cell and How Does It Go Bad
 
  Yuanyuan Wang †, UCLA
Short Talk: Unraveling Stemness Mechanisms in MECOM Rearranged Acute Myeloid Leukemias
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Friday, February 27, 2026
12:00–11:59 PM Departure