Antibodies as Drugs: Evolving Designs, Formats and Approaches (K7)
February 22-25, 2027
| Fairmont Banff Springs, Banff, AB, Canada
James E Crowe, Jr., Lisa Purcell and Jonah Rainey
Monday, February 22, 2027
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Tuesday, February 23, 2027
| 8:00–8:10 AM |
Welcome Remarks (Joint) |
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| 8:10–9:00 AM |
Keynote Address (Joint) |
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James Zou, Stanford University
The Virtual Lab |
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| 9:00–11:15 AM |
Drug Design and Preclinical Development: Stimulating Therapeutics and Translation (Joint) |
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Dean Ho, National University of Singapore
Simulating First-in-Human Dosing Studies in Oncology |
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Philip Kim, University of Toronto
Computation and Artificial Intelligence-Based Methods for Better Antibody Development |
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Mohamed Shahin †, Pfizer
Modeling and Simulations Meet AI for Clinical Pharmacology |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Bispecific Antibodies for Co-Engagement and Co-Stimulation |
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Shelley Force Aldred, Rondo Therapeutics
T-Cell Co-Stimulatory Bispecific Antibodies for Treating Solid Tumors |
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Koorosh Korfi †, Roche
CD28 and 4-1BB Costimulation in Combination Therapies |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, February 24, 2027
| 8:00–11:00 AM |
New Dosing and Use Paradigms for Multispecific Antibodies |
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Paul W. H. I. Parren, Leiden University Medical Center
Deep-Depletion of Tissue-Resident Pathogenic Immune Cells |
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Yvonne Y. Chen †, University of California, Los Angeles
Bispecific Logic-Gated CAR-T Cells |
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Nina Weisser, Zymeworks BC Inc.
TriTCE Co-stim: A Differentiated T Cell Engager Platform with Conditional cis CD28 Co-Stimulation and Transferability to Diverse Targeting Strategies |
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Peyton Greenside †, BigHat Biosciences
TCE for Diverse Targets |
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Jonah Rainey, Lilly
Talk Title to be Announced |
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Short Talk(s) Chosen from Abstracts
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|
| 9:00–9:20 AM |
Coffee Break |
|
| 11:00–1:00 PM |
Poster Setup |
|
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:30 PM |
Conditionally and Selectively Active Antibodies |
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Meike Logtenberg, Merida Biosciences
Selective Binding and Clearance of Pathogenic Antibodies |
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Cathy Chang †, BioAlta, LLC.
Protein-Associated Chemical Switches for Conditionally Active Biologics |
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Short Talk(s) Chosen from Abstracts
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| 6:30–7:00 PM |
Panel Discussion 1: The Cutting-Edge of Antibody Engagement |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Thursday, February 25, 2027
| 8:00–11:00 AM |
Application of Innovations to Exogenous Antibody Targets to Expand Breadth and Efficacy |
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David Veesler, University of Washington
Antibody Inhibition of Activation Mechanisms of Coronavirus Spike |
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Laura M Walker, Moderna
Alternative Expression of Antibodies |
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James E Crowe, Jr., Vanderbilt University Medical Center
Human Monoclonal Antibodies for Emerging Infectious Diseases |
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Lisa Purcell, Third Rock Ventures
Novel Structure-Guided Functional Improvement of Antibody Breadth and Potency |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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| |
Short Talks Chosen from Abstracts
|
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:30 PM |
Novel Scaffolds and Immunoconjugates |
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Bradley Pentelute †, Massachusetts Institute of Technology
Efficient Drug Delivery through Selective Modification of Proteins |
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Jason Laliberte, AstraZeneca
VHH-Based Antibodies for Broad Influenza Targeting |
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Short Talk(s) Chosen from Abstracts
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| 6:30–7:00 PM |
Panel Discussion 2: How Far Is Too Far: Target Engagement, Computational Design and New Scaffolds |
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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Friday, February 26, 2027
