Antibodies as Drugs: Evolving Designs, Formats and Approaches (K7)
      
      
      
      
      
      February 22-25, 2027
       | Fairmont Banff Springs, Banff, AB, Canada
      
      
      
         
          James E Crowe, Jr., Lisa Purcell and Jonah Rainey
        
            
      
      
      
          
      
   
            
     
          
    
      
      
        
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
        
          
            Monday, February 22, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 4:00–8:00 PM | 
            Registration | 
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            | 6:00–8:00 PM | 
            Welcome Mixer | 
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            Tuesday, February 23, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–9:00 AM | 
            Welcome and Keynote Address (Joint) | 
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            |   | 
            James Zou †, Stanford University The Virtual Lab | 
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            | 9:00–11:15 AM | 
            Drug Design and Preclinical Development: Stimulating Therapeutics and Translation (Joint) | 
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            |   | 
            Dean Ho †, National University of Singapore Simulating First-in-Human Dosing Studies in Oncology | 
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            |   | 
            Regina Barzilay †, Massachusetts Institute of Technology ML for Drug Discovery and Oncology Success Stories | 
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            |   | 
            Philip Kim †, University of Toronto Computation and Artificial Intelligence-Based Methods for Better Antibody Development | 
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            |   | 
            Mohamed Shahin †, Pfizer Modeling and Simulations Meet AI for Clinical Pharmacology | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 9:30–9:50 AM | 
            Coffee Break | 
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            | 11:15–1:00 PM | 
            Poster Setup | 
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            | 11:15–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–10:00 PM | 
            Poster Viewing | 
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            | 2:30–4:30 PM | 
            Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions | 
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            |   | 
            Short Talks Chosen from Abstracts
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–7:00 PM | 
            Bispecific Antibodies for Co-Engagement and Co-Stimulation | 
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            |   | 
            Shelley Force Aldred †, Rondo Therapeutics Co-Stimulatory Bispecifics | 
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            |   | 
            Koorosh Korfi †, Roche CD28 and 4-1BB Costimulation in Combination Therapies | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            Wednesday, February 24, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–11:00 AM | 
            New Dosing and Use Paradigms for Multispecific Antibodies | 
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            |   | 
            Ton M. Logtenberg †, Gyes B.V./Olethros Deep-Depletion of Tissue-Resident Pathogenic Immune Cells | 
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            |   | 
            Yvonne Y. Chen †, University of California, Los Angeles Bispecific Logic-Gated CAR-T Cells | 
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            |   | 
            Nina Weisser †, Zymeworks BC Inc. Trispecific T-Cell Engagers | 
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            |   | 
            Peyton Greenside †, BigHat Biosciences TCE for Diverse Targets | 
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            |   | 
            Jonah Rainey, Lilly Talk Title to be Announced | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 9:00–9:20 AM | 
            Coffee Break | 
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            | 11:00–1:00 PM | 
            Poster Setup | 
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            | 11:00–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–10:00 PM | 
            Poster Viewing | 
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            | 3:00–4:30 PM | 
            Career Roundtable | 
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            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–6:30 PM | 
            Conditionally and Selectively Active Antibodies | 
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            |   | 
            Meike Logtenberg †, Merida Biosciences Selective Binding and Clearance of Pathogenic Antibodies | 
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            |   | 
            Cathy Chang †, BioAlta, LLC. Protein-Associated Chemical Switches for Conditionally Active Biologics | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 6:30–7:00 PM | 
            Panel Discussion 1: The Cutting-Edge of Antibody Engagement | 
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            Thursday, February 25, 2027
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–11:00 AM | 
            Application of Innovations to Exogenous Antibody Targets to Expand Breadth and Efficacy | 
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            |   | 
            David Veesler †, University of Washington Antibody Inhibition of Activation Mechanisms of Coronavirus Spike | 
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            |   | 
            Laura M Walker †, Moderna Alternative Expression of Antibodies | 
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            |   | 
            James E Crowe, Jr., Vanderbilt University Medical Center Talk Title to be Announced | 
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            |   | 
            Lisa Purcell, Third Rock Ventures Novel Structure-Guided Functional Improvement of Antibody Breadth and Potency | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 9:00–9:20 AM | 
            Coffee Break | 
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            | 11:00–5:00 PM | 
            On Own for Lunch | 
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            | 2:30–4:30 PM | 
            Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions | 
             | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Short Talks Chosen from Abstracts
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              | 
          
        
        
                
        
       
      
    
      
           
      
  
      
        
        
        
          
            | 4:30–5:00 PM | 
            Coffee Available | 
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            | 5:00–6:30 PM | 
            Novel Scaffolds and Immunoconjugates | 
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            |   | 
            Bradley Pentelute †, Massachusetts Institute of Technology Efficient Drug Delivery through Selective Modification of Proteins | 
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            |   | 
            Pawel Stocki †, Ossianix Brain Shuttles for Targeted Delivery | 
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            |   | 
            Jason Laliberte †, AstraZeneca VHH-Based Antibodies for Broad Influenza Targeting | 
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            Short Talk(s) Chosen from Abstracts
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            | 6:30–7:00 PM | 
            Panel Discussion 2: How Far Is Too Far: Target Engagement, Computational Design and New Scaffolds | 
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            | 6:45–7:00 PM | 
            Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | 
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
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            | 8:00–11:00 PM | 
            Entertainment | 
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            Friday, February 26, 2027