Precision Genome Engineering: From Basic Mechanisms to Application (L1)
March 9-12, 2026
| Fairmont Banff Springs, Banff, AB, Canada
Jonathan S. Weissman, Cecilia Cotta-Ramusino and Joseph Bondy-Denomy
Scholarship Deadline: Nov. 7, 2025 | Abstract Deadline: Feb. 18, 2026 | Early Registration Deadline: Jan. 9, 2026
| 4:00–8:00 PM |
Registration |
Van Horne Foyer |
| 6:00–8:00 PM |
Welcome Mixer |
Van Horne Foyer |
| 7:00–8:00 AM |
Breakfast |
President's Hall |
| 8:00–9:00 AM |
Welcome and Keynote Session (Joint) |
Van Horne A/B |
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Jennifer A. Doudna, HHMI/University of California, Berkeley
CRISPR Enzyme Evolution and Applications |
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| 9:00–11:15 AM |
Delivery (Joint) |
Van Horne A/B |
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Daniel J. Siegwart, University of Texas Southwestern Medical Center
New LNP Modalities for Target Lung, Heart and Other Tissues |
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Michael A. Fischbach, Stanford University
Engineered Viral-Like Particle for Targeted Delivery of Gene Editors |
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Leah R Sabin, Regeneron Pharmaceuticals
Antibody-AAV Targeting: Fundamental Principle Behind Achieving BBB Crossing |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
Van Horne Foyer |
| 9:50–9:55 AM |
Award Recipient Acknowledgement |
Van Horne A/B |
| 11:15–1:00 PM |
Poster Setup |
Van Horne C |
| 11:15–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Van Horne C |
| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
Van Horne A |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
| 5:00–7:00 PM |
New Editing Modality |
Van Horne A |
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Samuel H Sternberg, Columbia University
CRISPR Guided Transposons |
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Patrick D. Hsu, Arc Institute | University of California, Berkeley
Bridge RNA-Directed Programmable Recombination |
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Cecilia Cotta-Ramusino, Tessera Therapeutics
Discovery and Application of New Gene Editing Modalities to Treat Disease |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
President's Hall |
| 7:30–10:00 PM |
Poster Session 1 |
Van Horne C |
Wednesday, March 11, 2026
| 7:00–8:00 AM |
Breakfast |
President's Hall |
| 8:00–11:00 AM |
Understanding and Therapeutic Application of CRISPR |
Van Horne A |
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Emma Wang, YolTech Therapeutics
Design of Therapeutic Editors Aided by AI and High Throughput Approaches |
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Xiao Wang, University of Pennsylvania
Developing Bespoke Gene Editing Treatments for Patients with Carbamoyl Phosphate Synthetase 1 (CPS1) Deficiency in Real Time: Successes and Challenges |
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Britt Adamson, Princeton University
DNA Damage Response and CRISPR |
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Benjamin P. Kleinstiver, Massachusetts General Hospital
Engineered Technologies for Modifying Single Bases to Several Kilobases |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Van Horne Foyer |
| 11:00–1:00 PM |
Poster Setup |
Van Horne C |
| 11:00–5:00 PM |
On Own for Lunch |
|
| 1:00–10:00 PM |
Poster Viewing |
Van Horne C |
| 3:00–4:30 PM |
Career Roundtable (Joint) |
Van Horne B |
| 4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
| 5:00–7:00 PM |
Intersection of Gene Editing High Throughput Screening and Machine Learning |
Van Horne A |
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Hyongbum Henry Kim, Yonsei University College of Medicine
Experimental and Machine Learning Approaches to Create New Genome Editing Tools |
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Jonathan S. Weissman, Whitehead Institute, HHMI, and MIT
In vivo Multiple Modal Information-Rich CRISPR Screens |
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Randall J. Platt, ETH Zurich
Functional Genomic Approaches |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
President's Hall |
| 7:30–10:00 PM |
Poster Session 2 |
Van Horne C |
| 7:00–8:00 AM |
Breakfast |
President's Hall |
| 8:00–11:00 AM |
Therapeutic Application |
Van Horne A |
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Jennifer Gori, Prime Medicine, Inc.
Application of Prime Editing to Treat Disease |
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Haihua Chu, Beam Therapeutics
Unlocking the Potential of base Edited HSCs for Therapeutic Applications with Epitope Engineering |
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Laura Sepp-Lorenzino, Intellia Therapeutics
TTR Therapies |
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Luigi M. Naldini, San Raffaele Telethon Institute for Gene Therapy
Gene Editing: Therapeutics and Genotoxicity |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
Van Horne Foyer |
| 11:00–5:00 PM |
On Own for Lunch |
|
| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
Van Horne A |
| |
Short Talks Chosen from Abstracts
|
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| 4:30–5:00 PM |
Coffee Available |
Van Horne Foyer |
| 5:00–6:45 PM |
CRISPR Biology |
Van Horne A |
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Joseph Bondy-Denomy, University of California, San Francisco
AntiCRISPR Phage Defense Against CRISPR Systems |
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Mitchell R. O'Connell, University of Rochester Medical Center
Pulling the Plug on Bacteriophage Infection: The Pore Behavior of CRISPR and Anti-phage Defense Associated Membrane Proteins |
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Elizabeth Kellogg, St. Jude Children's Research Hospital
Mechanism of Programmable Transposases |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions |
Van Horne A |
| 7:00–8:00 PM |
Social Hour with Dinner |
President's Hall |
| 8:00–11:00 PM |
Entertainment |
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