B Cells in Health and Disease (L2)
March 19-22, 2028  | Hershey Lodge, Hershey, PA, United States
Mark J. Shlomchik, Chloe Slichter and Ari M. Melnick
* Session Chair † Invited but not yet accepted | Program current as of October 13, 2026 7 PM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, March 19, 2028
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Monday, March 20, 2028
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–8:40 AM Welcome Remarks (Joint)
8:40–9:30 AM Keynote Address (Joint)
  Gabriel D Victora †, Rockefeller University/HHMI
Replaying Germinal Center Evolution
 
9:30–11:45 AM Germinal Center Biology (Joint)
  Peter Sage †, Harvard Medical School
Altered Tfh-Tfr Communication in Generating Pathogenic B Cells in Allergies, Autoimmunity and Transplantation
 
  Carla R. Nowosad †, New York University
Germinal Center Responses at Mucosal Sites
 
  Oliver Bannard †, University of Oxford
Selection and Differentiation in Germinal Center B Cells
 
  Short Talk(s) Chosen from Abstracts
 
10:00–10:20 AM Coffee Break
11:45–12:45 PM Lunch
12:30–2:30 PM Posters
2:30–4:30 PM Symposia Spotlight 1
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Autoimmune B Cell-Driven Disease Mechanisms
  Ignacio Sanz †, Emory University, School of Medicine
Pro-Inflammatory B Cell Subsets and Extrafollicular Responses that Drive Systemic Autoimmunity
 
  Anne-Katrin Pröbstel †, University Basel
B Cells, Microbiota, and Neuroinflammatory Diseases
 
  Marta Rizzi †, University Medical Center Freiburg
B Cell Defects in Human Autoimmune Diseases
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM On Own for Dinner
Tuesday, March 21, 2028
7:30–8:30 AM Breakfast
8:00–8:30 AM Poster Setup
8:15–5:00 PM Poster Viewing
8:30–11:30 AM Vaccines and B Cell Memory
  Wei Luo †, Indiana University School of Medicine
Strategies to Generate Broad and Effective Immune Responses for Vaccine Efficacy
 
  Michel C. Nussenzweig †, HHMI/Rockefeller University
Engineering Effective Vaccine Responses
 
  Chris Scharer †, Emory University
Origins and Properties of Memory B Cells
 
  Sarah F Andrews †, National Institutes of Health
Human Immune Responses to Influenza
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:30–12:30 PM Lunch
12:30–2:30 PM Posters
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM Pathogenic B and T Cell Populations (Joint)
  Mark J. Shlomchik, University of Pittsburgh School of Medicine
Extrafollicular Responses and ABCs
 
  Nicole Baumgarth †, Johns Hopkins Bloomberg School of Public Health
Non-Canonical B Cell Responses
 
  Joseph E. Craft †, Yale University
Cellular Immunopathogenesis in Lupus Nephritis
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM On Own for Dinner
Wednesday, March 22, 2028
7:30–8:30 AM Breakfast
8:30–11:30 AM B Cell Malignancies
  Ari M. Melnick, Josep Carreras Leukaemia Research Institute
Genetic and Epigenetic Drivers of B Cell Lymphomas and How They Can Dictate Precision Therapeutic Approaches
 
  Sandrine Roulland †, Aix Marseille University
Heterogeneity of B Cell Lymphomas and How They Interact with Their Environment
 
  Margaret Shipp †, Dana-Farber Cancer Institute
Designing and Selecting Therapies for B Cell Lymphomas
 
  Dinis P Calado †, Francis Crick Institute
Malignant Transformation of Germinal Center B Cells
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
12:40–1:40 PM Lunch
2:30–4:30 PM Symposia Spotlight 2
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM Targeting B Cells via Diverse Approaches
  Chloe Slichter, Kite Pharma
CAR T Cells to Treat Cancer and Autoimmunity
 
  Erick Lu †, Gilead Sciences
Bi-Specific T cell Engagers to Treat Autoimmune Diseases
 
  Gwendolyn Binder †, Cabaletta Bio
Novel CAR19 T Approaches for Diverse Autoimmune Diseases
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM On Own for Dinner
Thursday, March 23, 2028
12:00–11:59 PM Departure