B Cells and Plasma Cells: Fundamental and Translational Biology (L3)
March 16-19, 2026
| Keystone Resort, Keystone, CO, United States
Kim Good-Jacobson, Deepta Bhattacharya and Taras Kreslavsky
Scholarship Deadline: Nov. 14, 2025 | Abstract Deadline: Feb. 24, 2026 | Early Registration Deadline: Jan. 15, 2026
| 12:00–3:00 PM |
CU Anschutz Pre-Conference Workshop: Networking & Communication Skills (separate registration required) Learn more at: https://keysym.us/CUAnschutz26 |
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| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–8:10 AM |
Welcome Remarks (Joint) |
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| 8:10–9:00 AM |
Keynote Address (Joint) |
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Carola G. Vinuesa, Francis Crick Institute
Regulation of Humoral Immunity |
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| 9:00–11:30 AM |
Generation and Maintenance of Humoral Memory (Joint) |
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Kim Good-Jacobson, Monash University
Memory B Cells and Plasma Cells in Acute and Chronic Viral Infections |
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Taras Kreslavsky, Karolinska Institutet
The Multilayered Identity of B Cell Memory |
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Frances E. Lund, University of Alabama at Birmingham
Pathogen-Specific Memory B Cell Subsets and Antibody Production |
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Shane Crotty, La Jolla Institute for Immunology
Short Talk: Germline-Targeting Vaccine Elicits HIV Broadly Neutralizing Antibodies In Nonhuman Primates |
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Gowthaman Uthaman, University of Massachusetts Chan Medical School
Short Talk: Lymph Node ILC2s Drive Tfh13 Cell Differentiation and Anaphylactic IgE Responses |
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| 9:30–9:50 AM |
Coffee Break |
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| 11:30–1:00 PM |
Poster Setup |
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| 11:30–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 1:15–2:15 PM |
Meet the Editors (Joint) |
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| 2:30–4:30 PM |
Symposia Spotlight 1 |
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Kai-Michael Toellner, Babraham Institute
Increased B Cell Receptor Signalling During Development Leads to Widespread B Cell Anergy |
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Ashima Shukla, Northwestern University
Regulation of B Cell Fate and Function by B Cell Receptor Isotypes |
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Stephen Joachim, University of Pittsburgh
Apparent Self-Tolerance of Commensal-Specific B Cells And Their Responses to Infection |
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Romain G Gailleton, Gothenburg University
The Nasal Influenza-Specific Memory B Cells at the Frontline of Respiratory Immunity |
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Jacqueline White, Garvan Institute of Medical Research
The Impact of Subcellular Localisation of Self-Antigen on B cell Self-Tolerance following Primary and Secondary BCR Diversification |
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William Foster, NYU Langone Health
TLR Signaling Uniquely Tunes Gut B Cell Activation to Maintain Microbial Homeostasis |
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Hyeonuk Yeo, Seoul National University
Liver X Receptor Mediates Plasma Cell Resilience To Proteostatic Stress |
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Carly Roman, Emory University
RXR Orphan Nuclear Receptors Differentially Regulate B Cell Development And Differentiation |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Early Programming of Antibody Responses |
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Joan Yuan, Lund University
Early Life Programming of B Cells for Long-Lived Immunity |
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Wilton B. Williams, Duke University School of Medicine
Understanding B Cell Responses to HIV in Young Non-Human Primates and Human Children |
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Nicole Baumgarth, Johns Hopkins Bloomberg School of Public Health
Non-Canonical B Cell Responses to Infections |
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Stephen L. Nutt, Walter and Eliza Hall Institute
Short Talk: The Diversity of Tissue Resident Plasma Cells |
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Andrea Reboldi, University of Massachusetts Chan Medical School
Short Talk: Dynamic Nutrient Sensing in Plasma Cells Licenses Immunoglobulin A Secretion |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 7:30–10:00 PM |
Poster Session 1 |
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Wednesday, March 18, 2026
| 8:00–11:00 AM |
Host-Pathogen Interaction and Humoral-Mediated Vaccinology |
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Neil P King, University of Washington
ML-Enabled Antigen and Nanoparticle Vaccine Design |
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Taia T Wang, Stanford University
Defining Fc Receptor Repertoires in Effective vs Non-Effective Antibody Responses |
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Davide Corti, Vir Biotechnology
Discovery and Engineering of Antiviral Antibodies |
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Gabriel D. Victora, Rockefeller University
Quality and Quantity of B Cell Responses |
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Rosemary Aogo †, National Institutes of Health
Short Talk: Enhancing, Controlling and Sterilizing Immunity following Challenge with a Live-attenuated Dengue Vaccine |
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Gillian Quinn Horn, Duke University
Short Talk: Epstein-Barr Virus Reprograms B Cells Via EBNA2 to Induce T-bet+CXCR3+ B Cells Linked to Multiple Sclerosis |
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 1:30–3:15 PM |
Panel Discussion: Defining B Cell Subsets (Joint) |
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Frances E. Lund, University of Alabama at Birmingham
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Nicole Baumgarth, Johns Hopkins Bloomberg School of Public Health
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Stephanie C. Eisenbarth, Northwestern University Feinberg School of Medicine
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Kim Good-Jacobson, Monash University
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Jason G. Cyster, HHMI/University of California, San Francisco
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Mark J. Shlomchik, University of Pittsburgh School of Medicine
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Ziv Shulman, Weizmann Institute
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| 3:30–4:30 PM |
Career Roundtable (Joint) |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Humoral Helpers (Joint) |
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Tri G Phan, Garvan Institute of Medical Research
B Cell-Macrophage Interactions in Immunity and Autoimmunity |
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Michelle A Linterman, Malaghan Institute of Medical Research
Instruction of Antibody Responses Over Time |
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Laura M Walker, Moderna
Vaccine Induced Antibody Responses |
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David R Fooksman, Albert Einstein College of Medicine
Short Talk: Investigating the Rrle of CD138 and APRIL in the Plasma Cell Survival And Dynamics In The Bone Marrow Niche |
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Di Yu, University of Queensland
Short Talk: Lipid Metabolism Drives Dietary Effects on Ferroptosis In Tfh Cells and Modulates Humoral Immunity |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 7:30–10:00 PM |
Poster Session 2 |
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| 8:00–11:00 AM |
Translational Biology of Plasma Cells in Disease |
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Noopur Raje, Massachusetts General Hospital
Immunotherapy for Multiple Myeloma |
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Frances E Lee, Emory University
Antibody Diagnostics in Respiratory Disease |
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Jamie M Orengo, Regeneron Pharmaceuticals Inc.
Drivers of Allergic Antibody Responses |
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Mariana Waldetario †, Mount Sinai
Short Talk: Long-Lived Lge Plasma Cells That Reside In The Spleen Contribute To The Persistence Of The Lge Response |
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Mariasilvia Colantuoni, Boston Children's Hospital
Short Talk: Linking Genetic Risk to B Cell Dysfunction: Mechanisms of IL12A-mediated DN2 B cell Expansion in Lupus |
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Joseph Choi, Vanderbilt University Medical Center
Short Talk: Defects in B Cell Differentiation and Antibody Production are the Hallmarks of Novel Human Inborn Error of Immunity Caused by TANK Deficiency |
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Anouk G van Mourik, Leiden University Medical Center
Short Talk: Tailpiece-Mediated Dimerization: A Cornerstone of IgA Biology |
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2 |
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Koushik Roy, University of Utah
NFkB cRel Regulates Memory B cells Growth and Differentiation into Plasma Cells |
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Yolanda Garcia-Carmona †, Icahn School of Medicine at Mount Sinai
TACI Isoforms And Endogenous APRIL in B Cell Maturation |
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Hayley Groover, The Ohio State University
Age-Associated Expansion of Natural IgM+ Fcrl5+ B1 Cell Clones in a Model of Progressive Multiple Sclerosis: Drivers of Disease and Targets for Therapy |
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Eric Zhang, Columbia University Medical Center
Tissue-Directed Maintenance Of Human B-Cell Memory After Vaccination And Infection |
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Rebecca Francis, Rutgers University
Graded Tbet Expression Defines Effector Functions of Activated B Cells During Acute Infection |
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An Qi Xu, The Francis Crick Institute
A Layered Architecture Of Plasma Cell Longevity Reveals How Memory B Cell Recall Drives Long-Lived Immunity |
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Pengcheng Zhou, Rockefeller University
B Lymphocytes That Enter The Germinal Center Late Preferentially Differentiate Into Memory Cells That Recognize Subdominant Epitopes |
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Emily Siniscalco †, Yale University
Sequential Class Switching Generates Antigen-Specific Gut IgA from IgG1 B Cells |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Regulation of Antibody and Memory Responses |
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Deepta Bhattacharya, University of Arizona
Molecular Imprinting of Durable Antibody Responses |
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Marion Pepper, University of Washington
Regulation of Memory Responses to Plasmodium and Vaccine Design |
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Wataru Ise, CiDER, Osaka University
The Instruction Manual for Generating Long-Lived Plasma Cells |
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Marla Glass, Allen Institute
Short Talk: Discovery And Delineation Of Human Antibody-Secreting Cell Subsets |
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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