Cell Competition: Fitness, Diversity, and Adaptation Across Scales and Species (L4)
March 7-10, 2027
| Fairmont Hotel Vancouver, Vancouver, BC, Canada
Laura A. Johnston, Thomas P. Zwaka and Tristan A Rodriguez
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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| 8:00–9:00 AM |
Welcome and Keynote Address (Joint) |
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Benjamin L. Ebert †, Dana-Farber Cancer Institute
Clonal Expansions in the Hematopoetic System in Health and Disease |
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| 9:00–11:15 AM |
Joint Session |
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Laura A. Johnston, Columbia University
Cell Competition as a Framework for Diverse Areas of Biology |
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Nuria Lopez-Bigas, IRB Barcelona
Somatic Mosaicism and its Association to Cancer Risk |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–12:15 PM |
Flash Talks |
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| 12:15–1:00 PM |
Poster Setup |
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| 12:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Cell Competition as Quality Control I: Genome Integrity and Cellular Fitness |
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Yukiko M. Yamashita †, Whitehead Institute
Challenges to Genome Integrity in Spermiogenesis |
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Marco Milán †, IRB Barcelona
Aneuploidy and Cell Competition |
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Sarah Bowling †, Stanford University
Mutation of p53 Increases the Competitive Ability of Pluripotent Stem Cells |
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Short Talks Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Cell Competition as Quality Control II: Metabolism and Stress Surveillance |
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Marianthi Kiparaki †, Alexander Fleming Biomedical Sciences Research Center
Ribosomal Protein Mutations and Cell Competition: Autonomous and Nonautonomous Effects on a Stress Response |
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Jean-Paul B. Vincent †, Francis Crick Institute
Ribosomopathy-Associated Mutations cause Proteotoxic Stress that is Alleviated by TOR Inhibition |
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Tristan A Rodriguez, Imperial College London
Sensing of Extracellular L-Proline by the Integrated Stress Response in Cell Competition |
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Miguel Torres †, Centro Nacional de Investigaciones Cardiovasculares
P53 and BCL-2 Family Proteins Define Competitive Fitness in Pluripotent Cell Competition |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Flash Talks |
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| 12:00–1:00 PM |
Poster Setup |
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| 12:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–5:45 PM |
Keynote Address |
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Harmit S. Malik †, Fred Hutchinson Cancer Research Center
Conflicts, Conflicts Everywhere |
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| 5:45–7:00 PM |
Cell Competition in Tissue Formation |
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Leonard I. Zon †, HHMI/Boston Children's Hospital
Modeling Clonal Dynamics in Disease in Zebrafish |
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Stephanie Ellis †, Max Perutz Labs Vienna
Modes of Cell Competition in Skin Formation |
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Qingfeng Wu †, Chinese Academy of Sciences
Neural Cell Competition Sculpts the Brain |
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Romain Levayer †, Institut Pasteur
Interfacial Tension and Growth both Contribute to Mechanical Cell Competition |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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Wednesday, March 10, 2027
| 8:00–11:00 AM |
Homeostasis, Aging and Disease |
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Eugenia Piddini †, University of Bristol
Cell Competition and p53 in Epithelial Repair |
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Jun Wu †, University of Texas Southwestern Medical Center
Interspecies Chimerism and Cell Competition |
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Thomas P. Zwaka, Icahn School of Medicine at Mount Sinai
Bats as Instructive Animal Models for Cell Competition, Longevity and Aging |
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Coraline Mlynarczyk †, Yale University
Competitive Fitness in Germinal Center B Cells |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–12:00 PM |
Panel Discussion: Technological Innovations in Studying Cell Competition |
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Sarah Bowling †, Stanford University
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Jun Wu †, University of Texas Southwestern Medical Center
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| 11:00–5:00 PM |
On Own for Lunch |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–6:45 PM |
Integrating Old and New Models and Cellular Contexts |
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Kevin Foster †, University of Oxford
The Evolution of Short- and Long-Range Weapons for Bacterial Competition |
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Gillian Stanfield †, University of Utah
Migration-mediated Cell Competition |
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Ivana Barbaric †, University of Sheffield
Genetically Variant Human Pluripotent Stem Cells Eliminate WT cells through Yap-Mediated Cell Competition |
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Short Talk(s) Chosen from Abstracts
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| 6:45–7:00 PM |
Meeting Wrap-Up: Outcomes and Future Directions (Organizers) |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 PM |
Entertainment |
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