Early Life Immunity and Tolerance (L5)
March 7-10, 2027  | Fairmont Banff Springs, Banff, AB, Canada
Janelle S. Ayres, Gregory M. Barton and Carrie L. Lucas
Scholarship Deadline: Nov. 12, 2026 | Abstract Deadline: Feb. 16, 2027 | Early Registration Deadline: Jan. 7, 2027
* Session Chair † Invited but not yet accepted | Program current as of August 26, 2026 3 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, March 7, 2027
4:00–8:00 PM Registration Riverview Lounge
6:00–8:00 PM Welcome Mixer Riverview Lounge
Monday, March 8, 2027
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–8:10 AM Welcome Remarks (Joint) Cascade Ballroom
8:10–9:30 AM Keynote Address (Joint) Cascade Ballroom
  Lora V. Hooper, University of Texas Southwestern Medical Center
How Microbiota Controls Innate Immunity
 
  Sing Sing Way, Cincinnati Children's Hospital
Pediatric Infectious Diseases
 
9:30–9:50 AM Coffee Break Riverview Lounge
9:30–11:30 AM Microbiota and T Cells (Joint) Cascade Ballroom
  Kathy D. McCoy, University of Calgary
Long-Term Reprogramming of Monocytes by Commensal Bacteria during Early Life Improves Host Defence against Infection
 
  Ivaylo I. Ivanov, Columbia University
Innate–Adaptive Circuits in Commensal-Specific Immunity
 
  Fiona M. Powrie, University of Oxford
Host-Microbiota Interactions in IBD
 
11:30–1:00 PM Poster Setup Alberta/New Brunswick
11:30–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Alberta/New Brunswick
2:30–4:30 PM Symposia Spotlight 1: Next Generation Scientists doing Fundamental Research in this Area Alhambra Ballroom
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–7:00 PM Infection Defense in Early Life Alhambra Ballroom
  Janelle S. Ayres, The Salk Institute for Biological Studies
Early Life Host Defense Strategies
 
  Mathias Hornef, RWTH Aachen University
Neonatal Infections
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
7:30–10:00 PM Poster Session 1 Alberta/New Brunswick
Tuesday, March 9, 2027
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–11:00 AM Microbial Tolerance (Joint) Cascade Ballroom
  Ruth E. Ley, Max Planck Institute for Biology
Distinguishing Friend from Foe
 
  Gregory M. Barton, University of California, Berkeley
Tolerance in the Intestine
 
  Rodney D. Newberry, Washington University School of Medicine
Tolerance and IBD
 
  Tiffany C. Scharschmidt, University of California, San Francisco
Early Life Tolerance to Skin Commensal Bacteria
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break Riverview Lounge
11:00–1:00 PM Poster Setup Alberta/New Brunswick
11:00–3:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Alberta/New Brunswick
3:00–4:30 PM Career Roundtable (Joint) Alhambra Ballroom
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–7:00 PM Immune Development Alhambra Ballroom
  Erika L Pearce, Johns Hopkins University
Tissue Resident Macrophages
 
  Joan Yuan, Lund University
Developmental Programs and Early Life Events
 
  Speaker to be Announced
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
7:30–10:00 PM Poster Session 2 Alberta/New Brunswick
Wednesday, March 10, 2027
7:00–8:00 AM Breakfast Alberta/New Brunswick
8:00–11:00 AM Maternal Influence, Early Immunity and Tolerance Alhambra Ballroom
  Meghan A. Koch, Fred Hutchinson Cancer Research
Maternal Antibodies Regulate Gut Immunity in Early Life
 
  Tim Hand, University of Pittsburgh
Assembly of the Neonatal Microbiota and Necrotizing Enterocolitis
 
  Gérard Eberl, Institut Pasteur
Weaning Reaction
 
  Liza Konnikova, Yale University School of Medicine
Placental Biology/Premature Infants
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break Riverview Lounge
11:00–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Next Generation Scientists doing Translational/Clinical Research in this Area Alhambra Ballroom
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available Riverview Lounge
5:00–6:45 PM Pediatric Genetic Immune Disorders Alhambra Ballroom
  Carrie L. Lucas, Yale University
Inborn Errors of Immunity
 
  Dusan Bogunovic, Columbia University
Pediatric Immunology
 
  Speaker to be Announced
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Alhambra Ballroom
7:00–8:00 PM Social Hour with Dinner Alberta/New Brunswick
8:00–11:00 PM Entertainment
8:00–11:00 PM Cash Bar
Thursday, March 11, 2027
12:00–11:59 PM Departure