Chronic Kidney Disease: Emerging Mechanisms, Consequences and Targeted Treatments (M2)
      
      
      
      
      
      April 12-15, 2026
       | Fairmont Hotel Vancouver, Vancouver, BC, Canada
      
      
      
         
          Matthias Kretzler, Hiddo Lambers Heerspink, Olga G. Troyanskaya and Maria Chiara Magnone
        
            
      
      
      
          Scholarship Deadline: Dec. 10, 2025 | Abstract Deadline: Mar. 20, 2026 | Early Registration Deadline: Feb. 12, 2026
      
   
            
     
          
    
      
      
        
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 4:00–8:00 PM | 
            Registration | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 6:00–8:00 PM | 
            Welcome Mixer | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 7:30–8:30 AM | 
            Breakfast | 
            Vancouver Island Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:30–10:00 AM | 
            Welcome and Keynote Address | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Griffin P. Rodgers, National Institute of Diabetes, Digestive and Kidney Diseases Building the Village of Precision Medicine for Kidney Disease: NIDDK Vision for CKD in 2026 | 
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            | 10:00–10:20 AM | 
            Coffee Break | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 10:20–11:45 AM | 
            CKD Function and Failure; From Models to Man | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Melissa Hallow, University of Georgia Modelling Kidney Function: What Renal Physiology Teaches us in 2025 for CKD: Lessons Learned from Modeling Endothelin Function in CKD Trials | 
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            |   | 
            Samira Musah, Duke University Kidney Tissue Bioengineering for Patient Level Precision Medicine | 
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            |   | 
            Jonathan Himmelfarb, Mount Sinai School of Medicine Ex vivo Organ Cross Talk: Liver-Kidney System Defines Molecular Cross Talk in Toxin Induced CKD | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 11:45–1:00 PM | 
            Poster Setup | 
            British/Columbia Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 11:45–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–10:00 PM | 
            Poster Viewing | 
            British/Columbia Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 2:30–4:30 PM | 
            Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Short Talks Chosen from Abstracts
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            | 4:30–5:00 PM | 
            Coffee Available | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 5:00–7:00 PM | 
            Unraveling the Molecular Machinery of the Nephron in Function and Failure | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Laura Barisoni, Duke University Tissue is the Issue: AI Driven Image Analysis Maps Structural and Molecular Disease Trajectories | 
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            |   | 
            Katalin Susztak, University of Pennsylvania From Mapping to Mechanism to Medicine | 
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            |   | 
            Olga G. Troyanskaya, Princeton University Genes and Environment Driving CKD: Linking Environmental Exposures with Genetic Risk Assessment to Guide CKD Management | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
            Vancouver Island Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 7:30–10:00 PM | 
            Poster Session 1 | 
            British/Columbia Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
        
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 7:30–8:30 AM | 
            Breakfast | 
            Vancouver Island Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–8:30 AM | 
            Poster Setup | 
            British/Columbia Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:15–5:00 PM | 
            Poster Viewing | 
            British/Columbia Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:30–11:30 AM | 
            CKD in Obesity and Diabetes: Driving the Disease Burden in the Cardio Metabolic Pandemic | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Tamer Coskun, Eli Lilly & Company Obesity Driven Metabolic Reprogramming: From Metabolic Profiling to Drug Targets for Cardiorenal Disease | 
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            |   | 
            Katherine R. Tuttle, University of Washington Finally Breaking the Death Spiral of CKD: Mechanistic Trials Defining the Mode of Action of the Incretin System | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 9:30–9:50 AM | 
            Coffee Break | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 9:50–9:55 AM | 
            Award Recipient Acknowledgement | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 11:30–12:30 PM | 
            Lunch | 
            Vancouver Island Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 12:00–2:30 PM | 
            Poster Session 2 | 
            British/Columbia Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 4:30–5:00 PM | 
            Coffee Available | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 5:00–7:00 PM | 
            Primary Glomerular Diseases Driving CKD: Insight into a Rapidly Evolving Targeted Therapy Landscape | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Brad H Rovin, Ohio State University College of Medicine Innate Immunity Modulation in Lupus Nephritis, Bringing Insight from Trials Back to the Bench | 
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            |   | 
            Chee Kay Cheung, University of Leicester The Right Drug for the Right IgAN in 2025: Impact of Endothelin Blockade on Glomerular Manifestations of IgA Nephritis | 
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            |   | 
            Tobias B Huber, University Medical Center Hamburg-Eppendorf Understanding Filtration Barrier Failure Drives Novel Treatments in Nephrotic Syndrome | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 7:00–8:00 PM | 
            On Own for Dinner | 
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            Wednesday, April 15, 2026
          
           
         
      
        
      
  
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 7:30–8:30 AM | 
            Breakfast | 
            Vancouver Island Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:30–11:30 AM | 
            Genes and Kidney; Unique Opportunities for Targeted Therapies, Lessons Learned from ApoL1 and Beyond | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Whitney Besse, Yale School of Medicine Polycystic Kidney Disease: The Journey from Gene to Therapies | 
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            |   | 
            Martin Pollak, Beth Israel Deaconess Medical Center ApoL1 Biology and Kidney Disease | 
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            |   | 
            Akinlolu Ojo, University of Kansa ApoL1 across Continents: Lessons Learned on Gene Environment Interaction in H3 Africa KDRN | 
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            |   | 
            Glenn Chertow, Stanford University Lessons Learned from the First Trials Targeting ApoL1 Kidney Disease | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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              | 
          
        
        
                
        
       
      
    
      
           
      
  
      
        
        
        
          
            | 9:30–9:50 AM | 
            Coffee Break | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 11:30–5:00 PM | 
            On Own for Lunch | 
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            | 1:00–2:00 PM | 
            Panel: Perspectives: Personalized Medicine and Patient-Centered Strategies (joint) | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 2:30–4:30 PM | 
            Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Short Talks Chosen from Abstracts
  | 
              | 
          
        
        
                
        
       
      
    
      
           
      
  
      
        
        
        
          
            | 4:30–5:00 PM | 
            Coffee Available | 
            British/Columbia Foyer | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 5:00–6:45 PM | 
            Precision Clinical Trial Strategies for Kidney Disease | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
      
  
      
      
        
        
        
        
          
            |   | 
            Matthias Kretzler, University of Michigan Lessons Learned from Matching Patients Renal Pathobiology to Targeted Therapies in Glomerular Disease | 
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            |   | 
            Maria Chiara Magnone, Abiologics, Inc Platform Trials in CKD, State of the Art in 2026 | 
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            |   | 
            Hiddo Lambers Heerspink, University Medical Center Groningen Precision Medicine Trials in CKD: Bringing Molecular Understanding of CKD Drugs to Clinical Care | 
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            |   | 
            Short Talk(s) Chosen from Abstracts
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            | 6:45–7:00 PM | 
            Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | 
            British Ballroom | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 7:00–8:00 PM | 
            Social Hour with Dinner | 
            Vancouver Island Room | 
          
        
        
        
         
      
      
        
                
        
      
      
    
      
           
      
  
        
      
      
        
                
        
      
      
    
      
           
      
  
      
        
        
        
          
            | 8:00–11:00 PM | 
            Entertainment | 
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