Hormonal Influences on Immunity and Cancer Across the Lifespan (N1)
January 1-4, 2027
| Location to be Determined
Suzanne D. Conzen, Amy Moran and James V. DeGregori
| 4:00–8:00 PM |
Registration |
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| 6:00–8:00 PM |
Welcome Mixer |
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Saturday, January 2, 2027
| 8:00–9:00 AM |
Welcome and Keynote Address |
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Alberto Mantovani †, Humanitas University
Intersection of Inflammation and Cancer |
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| 9:00–11:15 AM |
Lifespan: Hormones, Age, Immunity and Cancer Risk- Population Level Data Sets the Stage |
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JoAnn E. Manson †, Harvard Medical School
Hormones and Cancer Risk: The NHS what does it Teach Us? |
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Duygu Ucar †, The Jackson Laboratory
Sexual-Dimorphism in Human Immune System Aging |
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Yin Cao †, Washington University in St. Louis
Aging as a Risk Factor for Cancer |
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Short Talk(s) Chosen from Abstracts
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| 9:30–9:50 AM |
Coffee Break |
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| 11:15–12:15 PM |
Workshop: Artificial Intelligence |
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| 11:15–1:00 PM |
Poster Setup |
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| 11:15–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 2:30–4:30 PM |
Symposia Spotlight 1: Neuroendocrine Immune Regulation of Cancer - the Host, the Cancer Cell and the Microenvironment |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Aging, Sex Differences and Immune Fitness in Cancer Risk AND Treatment |
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Joseph Unger †, Fred Hutchinson Cancer Center
Cancer Outcomes and Sex Differences- Across the Lifespan |
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Amy Moran, Oregon Health & Science University
Hormones as Immune Modifiers and Determinants of Immunotherapy Outcome |
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Fabio Conforti †, European Institute of Oncology
Sex Differences in the Efficacy of Immunotherapy for Various Cancers, with Immunotherapy being Less Effective in Women than in Men |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Life Events: Puberty, Pregnancy, Menopause, and Tumor Development |
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Virginia Borges †, University of Colorado Denver
Talk Title to be Announced |
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Suzanne D. Conzen, University of Texas Southwestern Medical Center
Pubertal Social Stressors and the Role of Glucocorticoid Receptor in Mammary Gland Development and Cancer Risk |
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Elizabeth A. Bonney †, University of Vermont
Pregnancy’s Influence on T Cell Regulation |
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Weiping Zou †, University of Michigan
B7-H4 as a Previously Unrecognized Onco-Fetal Immune Tolerance Checkpoint Driven by Progesterone Signaling |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–1:00 PM |
Poster Setup |
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| 11:00–5:00 PM |
On Own for Lunch |
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| 1:00–10:00 PM |
Poster Viewing |
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| 3:00–4:30 PM |
Career Roundtable |
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Aging in Bone Marrow, the Microenvironment and Immune Fitness vs. Senescence |
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Jennifer Trowbridge †, The Jackson Laboratory
Discovery of Mechanisms by Which the Aging Bone Marrow Microenvironment Drives Progression of Clonal Hematopoiesis to MDS |
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Stephen S. Chung †, UT Southwestern Medical Center
Aging, Hematopoiesis, Leukemia and the Neuroendocrine Signaling |
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Robert Cohen †, Calico Life Sciences
Clonal Hematopoiesis (CH): New Genes Linked to Cancer Risk and Aging-Related Phenotype |
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Short Talk(s) Chosen from Abstracts
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Metabolic and Hormonal Changes during Aging as a Driver of Tumorigenesis |
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Ana P. Gomes †, Lee Moffitt Cancer Center & Research Institute
Age-Driven Metabolic and Epigenetic Changes - Metastasis Formation |
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Ashani T. Weeraratna †, Johns Hopkins University
Sex-Dependent and Epigenetic Effects in the Aged Melanoma Tumor Microenvironment |
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Marcia C. Haigis †, Harvard Medical School
Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity |
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Johan Auwerx †, École Polytechnique Fédérale de Lausanne
Nuclear Receptors, Lifespan, Inflammation, Disease, Founded Several Companies |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 2:30–4:30 PM |
Symposia Spotlight 2: Epigenetics and Cancer Over the Lifespan - Tumor and the Microenvironment |
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Short Talks Chosen from Abstracts
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| 4:30–5:00 PM |
Coffee Available |
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| 5:00–7:00 PM |
Immunologic Age and Cancer Progression, Therapeutic Responses, and Patient Outcomes |
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Short Talk(s) Chosen from Abstracts
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Curtis J. Henry †, University of Colorado Cancer Center
Aging, Obesity, Inflammation and T Cell Function |
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Daniel Zabransky †, Johns Hopkins School of Medicine
Age-Related Divergence of the Immune Response to Immunotherapy |
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Zihai Li †, The Ohio State University
Sex Biases and Therapeutic Outcome in ImmunoOncology |
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| 7:00–8:00 PM |
Social Hour with Dinner |
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| 8:00–11:00 AM |
Aging Immune System, Gene -> Environment (Epigenetics) Interactions: Can we Achieve Better Prevention Over the Lifespan |
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Miriam Merad †, Mount Sinai School of Medicine
Hematopoietic Aging Promotes Cancer by Fueling IL-1⍺-Driven Myelopoiesis |
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David Furman †, Buck Institute for Research on Aging
Measuring Immune Function in Humans and Machine Learning Tools to Better Define the Role of the Immune System in Disease and Longevity |
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James V. DeGregori, University of Colorado Denver School of Medicine
Clonal Hematopoiesis and Cancer Prevention |
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Mark M. Davis †, Stanford University School of Medicine, Howard Hughes
Metrics of Immune Function over the Lifespan |
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Short Talk(s) Chosen from Abstracts
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| 9:00–9:20 AM |
Coffee Break |
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| 11:00–11:15 AM |
Meeting Wrap-Up: Outcomes and Future Directions |
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