| 4:00–8:00 PM | Registration | Macdonald Foyer |
| 6:00–8:00 PM | Welcome Mixer | Macdonald Foyer |
| 7:00–8:00 AM | Breakfast | Macdonald EF |
| 8:00–9:30 AM | Welcome and Keynote Session (Joint) | Macdonald ABCD |
| Christian Haass, Ludwig-Maximilians University Munich Modulation of Microglial Function |
| Astrid Iversen, University of Oxford Genomic Risk for Neuroinflammation |
| 9:30–9:50 AM | Coffee Break | Macdonald Foyer |
| 9:50–11:15 AM | Integrating Degeneration and Inflammation (Joint) | Macdonald ABCD |
| Malú Gámez Tansey, Indiana University School of Medicine Role of Central-Peripheral Neuroimmune Cross-Talk in Neurodegeneration |
| Bart De Strooper, University College London Key Inflection Points in Alzheimer’s Disease Pathogenesis |
| Short Talk(s) Chosen from Abstracts |
| 11:15–1:00 PM | Poster Setup | Macdonald EF |
| 11:15–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Macdonald EF |
| 2:30–4:30 PM | Panel Discussion: From Research to Clinical Practice | Macdonald AB |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Neurodegenerative Disease Diagnostic to Therapeutics | Macdonald AB |
| Yimin Zou, University of California, San Diego Planar Cell Polarity Proteins in Synapse Degeneration |
| Henne Holstege, Amsterdam UMC Biomarker for Centenarians |
| Matthias Brendel, LMU Munich Molecular Imaging with PET for Translation towards Therapeutics |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner | Macdonald EF |
| 7:30–10:00 PM | Poster Session 1 | Macdonald EF |
| 7:00–8:00 AM | Breakfast | Macdonald EF |
| 8:00–11:00 AM | Disease Overarching Mechanisms of Neurodegenerative Diseases | Macdonald AB |
| Julia TCW, Boston University Lipophagic Defect by APOE4 in AD Glia |
| Justin Ichida, USC Keck School of Medicine Using Patient Stem Cells to Identify Therapeutic Targets for Familial and Sporadic ALS |
| Aaron D. Gitler, Stanford University School of Medicine Single Cell Mechanisms of Neurodegeneration |
| Short Talk(s) Chosen from Abstracts |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 11:00–1:00 PM | Poster Setup | Macdonald EF |
| 11:00–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Macdonald EF |
| 1:15–2:45 PM | Perspectives: Personalized Medicine & Patient-Centered Strategies (Joint) | Macdonald ABCD |
| Short Talk(s) Chosen from Abstracts |
| 3:00–4:30 PM | Career Roundtable (Joint) | Macdonald AB |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–7:00 PM | Myeloid-Based Disease Mechanisms for Neurodegenerative Diseases | Macdonald AB |
| Donna M. Wilcock, Indiana University School of Medicine Therapeutic Trem2 Activation Ameliorates Amyloid-beta Deposition and Improves Cognition in the 5XFAD Model of Amyloid Deposition |
| Zhiqiang An, The University of Texas Health Science Center at Houston Antibodies Targeting the LILRB2/TREM2 Axis in AD |
| Marco Colonna, Washington University School of Medicine Microglial Neurodegeneration Mechanisms |
| Short Talk(s) Chosen from Abstracts |
| 7:00–8:00 PM | Social Hour with Dinner | Macdonald EF |
| 7:30–10:00 PM | Poster Session 2 | Macdonald EF |
| 7:00–8:00 AM | Breakfast | Macdonald EF |
| 8:00–11:00 AM | Drug Delivery (Joint) | Macdonald ABCD |
| Fiona C. Elwood, Janssen R&D Developing Drugs for CNS Disorders: Considerations for Therapies That Cross the BBB |
| Kate Monroe, Denali Therapeutics Human Genetics Identifies Novel Microglial Targeting Therapeutic Approaches for Alzheimer's Disease |
| Sebastian Boland, Prevail Therapeutics, Eli Lilly Talk Title to be Announced |
| Christopher J. Barnum, INmune Bio Inc. Selective Targeting of Soluble TNF to Mitigate Neuroinflammation in Neurodegenerative Diseases |
| Short Talk(s) Chosen from Abstracts |
| 9:00–9:20 AM | Coffee Break | Macdonald Foyer |
| 9:20–9:25 AM | Award Recipient Acknowledgement | Macdonald ABCD |
| 11:00–5:00 PM | On Own for Lunch | Macdonald EF |
| 2:30–4:30 PM | Symposia Spotlight: Late-breaking research presentations selected from abstract submissions | Macdonald AB |
| Short Talks Chosen from Abstracts |
| 4:30–5:00 PM | Coffee Available | Macdonald Foyer |
| 5:00–6:45 PM | Target-Based Therapeutics | Macdonald AB |
| Emma Mead, Oxford Drug Discovery Institute USP11 Inhibitors and tau Proteostasis |
| Haiyan Peng, Alnylam Pharmaceuticals The Application of RNAi Therapeutics in Neurodegenerative Diseases |
| Marcos Costa, F. Hoffmann-La Roche Ltd Correcting RNA Mis-Splicing in TDP-43 Proteinopathy |
| Short Talk(s) Chosen from Abstracts |
| 6:45–7:30 PM | Closing Keynote Address | Macdonald AB |
| Dennis J. Selkoe, Harvard Medical School A Century of Alzheimer’s Research – Did We Finally Reach Our Goal? |
| 7:30–7:45 PM | Meeting Wrap-Up: Outcomes and Future Directions | Macdonald AB |
| 7:45–8:45 PM | Social Hour with Dinner | Macdonald EF |
| 8:00–9:00 PM | Entertainment | MacDonald CD |
| 8:00–9:00 PM | Cash Bar | Macdonald EF |
| 12:00–11:59 PM | Departure |