Ending HIV: At the Crossroads of Innovation and Delivery (N4)
May 16-19, 2027  | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Julie Ake, Esper Georges Kallas, Darrell J. Irvine and Jeff Murry
Scholarship Deadline: Jan. 20, 2027 | Abstract Deadline: Apr. 27, 2027 | Early Registration Deadline: Mar. 18, 2027
* Session Chair † Invited but not yet accepted | Program current as of August 26, 2026 1 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Sunday, May 16, 2027
4:00–8:00 PM Registration British/Columbia Foyer
6:00–8:00 PM Welcome Mixer British/Columbia Foyer
Monday, May 17, 2027
7:30–8:30 AM Breakfast Pacific Ballroom, Vancouver Island Room
8:30–8:40 AM Welcome Remarks (Joint) British/Columbia Ballroom
8:40–9:30 AM Keynote Address (Joint) British/Columbia Ballroom
  Michel C. Nussenzweig, HHMI/Rockefeller University
Immune Strategies to Combat Infectious Diseases: What Works and What Doesn't
 
9:30–12:00 PM Transformative Technologies for Infectious Disease Therapeutics and Vaccines (Joint) British/Columbia Ballroom
  Debora Marks, Harvard Medical School
Beating Viruses at their Own Game
 
  Kevin Wiehe, Duke University
Mutation Guided Immunogen Design
 
  Pamela J Bjorkman, California Institute of Technology
Structure based Vaccine Design
 
  Darrell J. Irvine, Scripps Research Institute
Harnessing Novel Vaccine Dosing and Adjuvant Strategies
 
10:00–10:20 AM Coffee Break British/Columbia Foyer
12:10–1:10 PM Panel Discussion 1: Vaccine Hesitancy and Distrust (Joint) British/Columbia Ballroom
12:55–2:00 PM Poster Setup Pacific Ballroom, Vancouver Island Room
1:10–2:30 PM On Own for Lunch
1:10–10:00 PM Poster Viewing Pacific Ballroom, Vancouver Island Room
2:30–4:30 PM Symposia Spotlight 1: Monoclonal Antibody Focus - Prevention or Cure Indications: Multi-Specific Antibodies, mAb Escape Columbia Ballroom
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available British/Columbia Foyer
5:00–7:00 PM Emerging Cure Concepts Columbia Ballroom
  Thumbi Ndung'u, University of KwaZulu-Natal
HIV Cure Strategies for the Global South
 
  David D Ho, Aaron Diamond AIDS Research Center (ADARC), Columbia University Medical Center
Novel Small Molecules for Cure
 
  Lishomwa C Ndhlovu, Weill Cornell Medicine
Transcriptional Silencing to Advance Remission
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner Pacific Ballroom, Vancouver Island Room
7:30–10:00 PM Poster Session 1 Pacific Ballroom, Vancouver Island Room
Tuesday, May 18, 2027
7:30–8:30 AM Breakfast
8:30–11:30 AM HIV Preclinical Pipeline Progress Columbia Ballroom
  Raiees A Andrabi, University of Pennsylvania
Broad HIV Neutralization by Targeted Sequential Vaccination
 
  Nicole A Doria-Rose, NIAID, National Institutes of Health
High throughput Monoclonal Antibody Discovery
 
  Mohamad-Gabriel Alameh, Children's Hospital of Philadelphia
Optimizing mRNA Vaccines for Cure and Preventive Indications
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break British/Columbia Foyer
11:30–1:00 PM Poster Setup Pacific Ballroom, Vancouver Island Room
11:30–2:30 PM On Own for Lunch
1:00–10:00 PM Poster Viewing Pacific Ballroom, Vancouver Island Room
2:30–3:30 PM Career Roundtable (Joint) Columbia Ballroom
3:30–4:30 PM Panel Discussion 2: Global Virus Network (Joint) Columbia Ballroom
4:30–5:00 PM Coffee Available British/Columbia Foyer
5:00–7:00 PM Frontiers of HIV Cure Columbia Ballroom
  Jeff Murry, Gilead Sciences
Novel Therapeutics Designed to Activate and Reduce Latent HIV Reservoirs
 
  Charity Wambui Kanyoro, Moi University College of Health Sciences
Dual Affinity Re-Targeting Proteins and Latency Reversal
 
  Michael J Peluso, University of California, San Francisco
Emerging Clinical Data: Cytokines and CAR-T Cells in HIV Cure
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner Pacific Ballroom, Vancouver Island Room
7:30–10:00 PM Poster Session 2 Pacific Ballroom, Vancouver Island Room
Wednesday, May 19, 2027
7:30–8:30 AM Breakfast Pacific Ballroom, Vancouver Island Room
8:30–11:30 AM Clinical Innovation in Immunologic HIV Countermeasures Columbia Ballroom
  Margaret J McElrath, Fred Hutchinson Cancer Center
Emerging Data from the HVTN Discovery Medicine Portfolio
 
  Julie Ake, Walter Reed Army Institute of Research
Rapidvax: Learning from the Lymph Node
 
  Esper Georges Kallas, University of São Paulo
Global Health Vaccines: Lessons from Instituto Butantan
 
  Richard M Dunham, ViiV Healthcare
The N6 Clinical Experience
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break British/Columbia Foyer
11:30–2:30 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Emerging Data from Vaccine and Cure Phase 1 Clinical Trials: GrAd Vectored HIV Vaccines, T Cell Engagers for Cure Columbia Ballroom
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available British/Columbia Foyer
5:00–6:45 PM Wrangling the Reservoir Columbia Ballroom
  Nadia R Roan, University of California, San Francisco
The Reservoir across Compartments: Everything Everywhere all at Once
 
  Amanda M. Brown, Johns Hopkins University School of Medicine
Fundamental Mechanisms Shaping Complex Sex-Dependent Inflammatory and Neuroendocrine Responses in HIV Infection
 
  Katharine J Bar, University of Pennsylvania
Strategies for Reservoir Reduction: Lessons from the ACTG Cure Portfolio
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions Columbia Ballroom
7:00–8:00 PM Social Hour with Dinner Pacific Ballroom, Vancouver Island Room
8:00–11:00 PM Entertainment
Thursday, May 20, 2027
12:00–11:59 PM Departure