Tumor and Host Metabolism: Integrating Molecular, Cellular, and Systemic Interactions (N6)
January 1-4, 2027  | Location to be Determined
Marcia C. Haigis
* Session Chair † Invited but not yet accepted | Program current as of September 6, 2025 3 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Friday, January 1, 2027
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Saturday, January 2, 2027
7:00–8:00 AM Breakfast
8:00–9:00 AM Welcome and Keynote Address
  Karen H. Vousden †, Francis Crick Institute
The Role of Diet and Metabolism on Tumor Progression
 
9:00–11:15 AM The Role of Diet and Microbiome on Cancer
  Sara Vieira-Silva †, University Medical Center Mainz
Tracking Microbial Metabolism in Health and Disease
 
  Semir Beyaz †, Cold Spring Harbor Laboratory
Nutrition Regulation of Intestinal Stem Cell Differentiation
 
  Ruaidhri P. Jackson †, Harvard Medical School
Gut Sensing Influences CRC Development
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:15–12:15 PM Meet the Editors
11:15–1:00 PM Poster Setup
11:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Specifically Targeting Tumor Mitochondria
4:30–5:00 PM Coffee Available
5:00–7:00 PM Innovative Technologies in Identifying Molecules and Pathways within the Tumor
  Michael Skinnider †, Princeton University
Machine Learning Approaches to Identify Metabolite-Tumor Interactions
 
  Garry P. Nolan †, Stanford University
Technologies to Decipher Single Cellular Interactions in the Tumor Microenvironment
 
  Joshua D. Rabinowitz †, Princeton University
Mass Spec Imaging of Tumor Metabolites
 
  Stacey D Finley †, University of Southern California
Integrative Computational Modeling Approaches to Determine the Impact of Genes on Metastatic Cancer Outcomes
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Sunday, January 3, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM The Role of Metabolites as Mediators of Tumor-Immune Interactions
  Hongbo Chi †, St. Jude Children's Research Hospital
In vivo T Cell Screening Approaches Reveal Novel Metabolite-Transcription Factor Interactions
 
  Leeat Keren †, Weizmann Institute of Science
Single Cell Spatial Analysis of Tumor and Immune Interactions
 
  Daniel J. Drucker †, Lunenfeld-Tanenbaum Research Institute
GLP-1 Targeting Connecting Weight Loss, Inflammation, and Cancer
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
3:00–4:30 PM Career Roundtable
4:30–5:00 PM Coffee Available
5:00–7:00 PM How Dietary Lipids Affects Host Metabolism to Control Tumor Progression
  Lydia Lynch, Princeton University
Source of Dietary Fats Influence Tumor – T Cell Recognition
 
  Alison Ringel †, Massachusetts Institute of Technology
Combinations of Dietary Lipids that Control T Cell Epigenetics
 
  Susan M Kaech †, The Salk Institute
Dietary Fatty Acids Control T Cell Fate
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Posters
Monday, January 4, 2027
7:00–8:00 AM Breakfast
8:00–11:00 AM Frontiers in Stress Responses and Aging in Cancer
8:00–11:00 AM Workshop: Cutting Edge Technology: Space and AI to Elucidate Mechanisms Complex Systemic to Cellular Crosstalk
  Marcia C. Haigis, Harvard Medical School
Role of Glutathione and Redox in Lung Cancer and Aging
 
  Ashani T. Weeraratna †, Johns Hopkins University
Tumor Stromal Interactions and Control of Metastasis and Clonality in Melanoma
 
  Sarah-Maria Fendt †, VIB-KU Leuven
Understanding Changes in NK Cell Immunity with Age
 
  Martin O. Bergo †, Karolinska Institutet
Redox Stress and Supplements and Tumor Progression
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Therapeutic Strategies Targeting Host – Tumor Interactions
  W. Kimryn Rathmell †, The Ohio State University
Therapeutic Targeting of Anti-Tumor Immunity in Kidney Cancer
 
  Jonathan D. Powell †, Calico Life Sciences
New Strategies for Targeting Cancer Immunotherapy and Cancer Metabolism
 
  Ping-Chih Ho †, Ludwig Institute for Cancer Research
Therapeutic Strategies to Target Tumor-Immune Crosstalk
 
  Carl H June †, University of Pennsylvania
CAR T Tuning Metabolism for Enhanced Persistence and Potency
 
  Short Talks Chosen from Abstracts
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Tuesday, January 5, 2027
12:00–11:59 PM Departure