| 4:00–8:00 PM | Registration | 3rd Floor Foyer |
| 6:00–8:00 PM | Welcome Mixer | 3rd Floor Foyer |
| 7:00–8:00 AM | Breakfast | Summit Gallery |
| 8:00–8:10 AM | Welcome Remarks (Joint) | Colorado Ballroom |
| 8:10–9:00 AM | Keynote Address (Joint) | Colorado Ballroom |
| Alexandra Trkola, University of Zürich HIV Vaccines: Learning from the Swiss X-BNAb Cohort for Prevention and Cure |
| 9:00–11:30 AM | Immune Interventions Interfacing HIV Prevention and Cure (Joint) | Colorado Ballroom |
| Mauricio A. Martins, University of Florida Promoting Persistent bNAb Expression in NHPs through AAV-Mediated Gene Transfer |
| Devi SenGupta, Gilead Sciences, Inc. Long-acting ART in HIV Prevention and Cure |
| Leonidas Stamatatos, Fred Hutchinson Cancer Research Center Vaccination of PLWH, using 426C Derived Immunogens |
| Cristina Ceriani, Emory University Short Talk: Influence of SIV Gag Vaccination on CD8⁺ T Cell Immunity and SIV Viral Dynamics |
| Nicolas M S Galvez Arriagada, Ragon Institute of Mass General, MIT and Harvard Short Talk: Vectored Delivery of bNAbs Prevents Rebound of Clinical HIV Isolate During Antiretroviral Therapy Interruption |
| 9:30–9:50 AM | Coffee Break | 1st Floor Foyer |
| 9:50–9:55 AM | Award Recipient Acknowledgement | Colorado Ballroom |
| 11:30–12:30 PM | Los Alamos HIV Immunology and Sequence Databases User Workshop | Colorado Ballroom |
| 11:35–1:00 PM | Poster Setup | Peaks 1 - 3 |
| 11:35–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Peaks 1 - 3 |
| 2:30–4:30 PM | Symposia Spotlight 1: Engineering Immunity to Control and Clear HIV | Breckenridge Ballroom |
| Archana V. Boopathy, Gilead Sciences Inc Combination of Ad5/MVA Vaccine with Immunomodulation Partially Prevents Rebound in Chronic SIVmac251-infected ART-suppressed Rhesus Macaques |
| Patricia A Hahn †, Wertheim UF Scripps Institute AAV-Vectored Delivery of eCD4-Ig and 10-1074 Enables Durable ART-Free Virologic Control in SHIV-Infected Rhesus Macaques |
| Chiara Hornung, University Hospital Cologne Long-Term Control of HIV-1 by AAVMYO-Mediated Expression of a Potent Broadly Neutralizing Antibody |
| Chia Jung Li, Ragon Institute of Mass General, MIT, and Harvard Epitope-Driven Fc Effector Functions of HIV-1 Broadly Neutralizing Antibodies are Enhanced via Fc Engineering |
| Kezia Singgih, The University of Melbourne Vδ2+ T-Cells in the Presence of Zoledronate Can Clear HIV Productively and Latently Infected CD4+ T-Cells: A Novel Strategy for Off-the-Shelf Therapy |
| Christopher D Stringham, Duke University A Non-Neutralizing MPER Antibody Induced Durable CD8 T Cell-Mediated Plasma Viral Load Control in SHIV-Infected Rhesus Macaques |
| Hiroshi Takata, Oregon Health and Science University Administration of the IL-15 Superagonist N-803 at the Time of ART Interruption Enhances NK and T Cell Proliferation And Activation Prior To Viral Rebound |
| Elena Vendrame, Gilead Sciences, Inc Safety, Pharmacokinetics, and Pharmacodynamics of Amtabafusp, a Bispecific T-Cell Engager, in Virologically Suppressed People with HIV-1 |
| 4:30–5:00 PM | Coffee Available | 1st Floor Foyer |
| 5:00–7:00 PM | Immune Targeting of HIV-1 Reservoir Cells: Obstacles and Opportunities | Breckenridge Ballroom |
| Brad Jones, Weill Cornell Medicine HIV Reservoir Cell Resistance to Immune-Mediated Killing |
| Michel C. Nussenzweig, HHMI/Rockefeller University HIV-1 Reservoir Dynamics |
| Kiera L. Clayton, University of Massachusetts Medical School NK Cell Targeting of the HIV Reservoir |
| Mihai L Azoitei, Duke University Short Talk: A New Strategy to Eliminate HIV Infected Cells by Targeting HLA-E-peptide Complexes with Engineered Monoclonal Antibodies |
| David D. Ho †, Aaron Diamond AIDS Research Center (ADARC), Columbia University Medical Center Short Talk: Activation of the HIV Latent Reservoir by a Bispecific Biological Construct and Elimination of Productively Infected Cells by a Pyroptotic Small Molecule |
| 7:00–8:00 PM | Social Hour with Dinner | Summit Gallery |
| 7:30–10:00 PM | Poster Session 1 | Peaks 1 - 3 |
| 7:00–8:00 AM | Breakfast | Summit Gallery |
| 8:00–11:00 AM | Tailoring Gene- and Cell-Therapy Approaches for HIV Cure: Promises and Pitfalls | Breckenridge Ballroom |
| Afam Okoye, Oregon Health & Science University Optimizing T Cell Responses for Post-ART Control |
| James L. Riley, University of Pennsylvania Immune-Based Cell Therapies |
| Lydie Trautmann, Military HIV Research Program Therapeutic Vaccine Trials in Humans |
| Daniel Dornbusch, Excision Bio Inc. CRISPR for HIV Cure: Human Clinical Trial Data |
| Sophie Sayettat, University Hospital Cologne Short Talk: Durable Suppression of Viremia by Lipid Nanoparticle-Formulated mRNA Encoding for a Highly Potent HIV-1 Neutralizing Antibody |
| Yiming Yin, Boston Children's Hospital Short Talk: In Vivo Affinity Maturation of Engineered B Cells Expressing HIV-1 bnAbs in Mice and Non-Human Primates |
| 9:00–9:20 AM | Coffee Break | 1st Floor Foyer |
| 11:00–1:00 PM | Poster Setup | Peaks 1 - 3 |
| 11:00–5:00 PM | On Own for Lunch |
| 1:00–10:00 PM | Poster Viewing | Peaks 1 - 3 |
| 1:30–2:45 PM | Health Equity Panel (joint) sponsored by The Burroughs Wellcome Fund | Breckenridge Ballroom |
| 3:00–4:30 PM | Career Roundtable (Joint) | Breckenridge Ballroom |
| 4:30–5:00 PM | Coffee Available | 1st Floor Foyer |
| 5:00–7:00 PM | Mechanisms of HIV Persistence: Insights and Innovations | Breckenridge Ballroom |
| Mathias Lichterfeld, Brigham and Women's Hospital Epigenetic Mechanisms of HIV Persistence |
| Roy Matkovic, Université de Paris, Institut Cochin The HUSH Complex and HIV Silencing |
| Nomonde N Bengu, Umkhuseli Innovations Sex Differences in HIV Reservoir Cell Persistence |
| Mirko Paiardini †, Emory University, ENPRC Short Talk: Repeated Enhancement of Antiviral Immune Responses Via IL-10 and PD-1 Blockades Durably Controls Viral Rebound and the Intact Reservoir Following ART Interruption in SIV-Infected Rhesus Macaques |
| Katharine J Bar, University of Pennsylvania Short Talk: Early ART and Autologous Neutralizing Antibodies Shape the HIV Reservoir and Rebound Virus Populations in an NHP Model of BnAb Therapy |
| 7:00–8:00 PM | Social Hour with Dinner | Summit Gallery |
| 7:30–10:00 PM | Poster Session 2 | Peaks 1 - 3 |
| 7:00–8:00 AM | Breakfast | Summit Gallery |
| 8:00–11:00 AM | No One Left Behind: HIV Cure Research Across the Age Continuum | Breckenridge Ballroom |
| Caroline T. Tiemessen, National Institute for Communicable Diseases HIV Immune Responses Across the Age Spectrum |
| Deborah Persaud, Johns Hopkins University School of Medicine HIV Remission in Infants |
| Roger Shapiro, Harvard School of Public Health Triple Combinations of Broadly-Neutralizing Antibodies in Children |
| Catherine K Koofhethile, Botswana Harvard Health Partnership Viral Reservoirs and Immune Responses in Adolescents and Young Adults with HIV |
| Siddappa Byrareddy †, University of Nebraska Medical Center Short Talk: Aging-Associated Expansion of HIV/SIV Reservoirs |
| Edna Ferreira, Johns Hopkins University Short Talk: Sex-Based Differences in HIV and SIV Cellular Reservoirs |
| 9:00–9:20 AM | Coffee Break | 1st Floor Foyer |
| 11:00–5:00 PM | On Own for Lunch |
| 1:15–2:15 PM | Meet the Editors (Joint) | Colorado Ballroom |
| 2:30–4:30 PM | Symposia Spotlight 2: Novel Approaches to Probe HIV Latency and Persistence | Breckenridge Ballroom |
| Catarina P Ananias Saez, Northwestern University A 3D Human Intestinal Organoid Model Reveals Gut-Driven Inhibition of HIV Transcription |
| Deanna A. Kulpa, Emory University Bcl-2 Inhibition Decreases the Established Intact Reservoir in SIV-infected, ART-Suppressed Rhesus Macaques |
| Ayisha Mahama †, University of South Dakota HIV gp120 Selectively Activates the IRE1α–XBP1 Pathway to Drive Microglial Inflammation |
| Grace Marshall, University of Miami Assessing the Chronicity of the HIV-1 Myeloid Reservoir |
| JC Mudd, Tulane national biomedical research center SIV and HIV-1 Proviruses are Preferentially Enriched in Genes that Become Down-Regulated upon CD4 T Cell Proliferation |
| Alexander O. Pasternak, Amsterdam UMC Majority of Infected Cells in Peripheral Blood of PWH on ART Transcribe Cell-Associated HIV-1 gag RNA |
| Julia Prigann, Gladstone Institutes Multimodal Silencing of HIV-1 Transcription by Human KRAB-Zinc Finger Proteins |
| Zoe R. Wallace, Immunocore TCR Labelling for Detection of HIV Reservoir Cells by Flow Cytometry |
| 4:30–5:00 PM | Coffee Available | 1st Floor Foyer |
| 5:00–6:30 PM | B Cell Responses and Broadly-Neutralizing Antibodies: Trials and Tribulations (Joint) | Colorado Ballroom |
| Marina F. Caskey, Rockefeller University Combined Immunotherapy with IL-15 Agonists and Broadly-Neutralizing Antibodies |
| Paula M Cannon, University of Southern California, Keck School of Medicine Engineering B Cells as in vivo bnAb Factories |
| William Schief, Moderna, Scripps, and IAVI Combining Germline Targeting Approaches Across Diverse bNAb Epitopes |
| 6:30–6:45 PM | Meeting Wrap-Up: Outcomes and Future Directions (Organizers) | Breckenridge Ballroom |
| 6:45–7:45 PM | Social Hour with Dinner | Summit Gallery |
| 7:45–8:45 PM | Entertainment | Colorado Ballroom |
| 7:45–8:45 PM | Cash Bar | Peaks 1 - 3 |
| 12:00–11:59 PM | Departure |