HIV Vaccines: Intersections of Basic and Clinical Science (P4)
April 16-19, 2026  | Beaver Run Conference Center, Breckenridge, CO, United States
Penny L Moore, Marit van Gils and Kevin O. Saunders
Scholarship Deadline: Dec. 17, 2025 | Abstract Deadline: Mar. 27, 2026 | Early Registration Deadline: Feb. 18, 2026
* Session Chair † Invited but not yet accepted | Program current as of August 23, 2025 8 AM | For the most up-to-date details, visit https://www.keystonesymposia.org
Thursday, April 16, 2026
4:00–8:00 PM Registration
6:00–8:00 PM Welcome Mixer
Friday, April 17, 2026
7:00–8:00 AM Breakfast
8:00–9:00 AM Welcome and Keynote Address (Joint)
  Alexandra Trkola, University of Zürich
HIV Vaccines: Learning from the Swiss X-BNAb Cohort for Prevention and Cure
 
9:00–11:15 AM Immune Interventions Interfacing HIV Prevention and Cure (Joint)
  Mauricio A. Martins, University of Florida
Promoting Persistent bNAb Expression in NHPs through AAV-Mediated Gene Transfer
 
  Devi SenGupta, Gilead Sciences, Inc.
Long-acting ART in HIV Prevention and Cure
 
  Leonidas Stamatatos, Fred Hutchinson Cancer Research Center
Vaccination of PLWH, using 426C Derived Immunogens
 
  Short Talk(s) Chosen from Abstracts
 
9:30–9:50 AM Coffee Break
11:15–1:00 PM Poster Setup
11:15–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
2:30–4:30 PM Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–7:00 PM Keeping up with the Changing HIV Envelope
  Penny L Moore, University of the Witwatersrand and National Institute for Communicable Diseases
African bNAb Immunogens
 
  Margaret E. Ackerman, Dartmouth College
Fc Effector Function in HIV Infection and Vaccination
 
  Aime Marcel Simon Tongo Passo, Center for Research on Emerging and Re-Emerging Diseases (CREMER/IMPM)
Viral Diversity in Central Africa: Known and Unknowns
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Poster Session 1
Saturday, April 18, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM The Vaccine Pipeline: Integrating Basic and Clinical Insights
  Speaker to be Announced
 
  Richard T. Wyatt, The Scripps Research Institute
Triggering bNAbs in Non-Human Primates
 
  Persephone Borrow, University of Oxford
Creating an Immune Environment Favorable for HIV-1 bnAb Induction
 
  Louis J. Picker, Oregon Health & Science University
Progress in CMV based Vaccines
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–1:00 PM Poster Setup
11:00–5:00 PM On Own for Lunch
1:00–10:00 PM Poster Viewing
1:30–2:45 PM Panel: Perspectives: Personalized Medicine & Patient-Centered Strategies (Joint)
3:00–4:30 PM Career Roundtable (Joint)
4:30–5:00 PM Coffee Available
5:00–7:00 PM Targeting the Needle in the Haystack: Clinical Trials of Germline Targeting Immunogens
  Kevin O. Saunders, Duke University
Induction of HCDR3-Binding and CD4 Mimicking Antibodies in HVTN300 and HVTN309
 
  Eunice Wambui Nduati, KEMRI, Wellcome Trust
Germline Targeting Immunogens and Precursors in African Populations
 
  Marit van Gils, Amsterdam UMC
Germline Targeting Immunogens in Human Clinical Trials; C101, C107, C110
 
  Short Talk(s) Chosen from Abstracts
 
7:00–8:00 PM Social Hour with Dinner
7:30–10:00 PM Poster Session 2
Sunday, April 19, 2026
7:00–8:00 AM Breakfast
8:00–11:00 AM Looking to the Future: New Tools, Platforms and Delivery Systems
  Eric A. Appel, Stanford University
Injectable Hydrogel Depot Technologies for Sustained Delivery of Vaccines
 
  Shannon Miller, Inimmune Corporation
Adjuvants for Mucosal Immunity
 
  Speaker to be Announced
 
  Rory Henderson, Duke University
Large Language Models to Identify bnAbs and Design Vaccines to Them
 
  Short Talk(s) Chosen from Abstracts
 
9:00–9:20 AM Coffee Break
11:00–5:00 PM On Own for Lunch
2:30–4:30 PM Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
  Short Talks Chosen from Abstracts
 
4:30–5:00 PM Coffee Available
5:00–6:45 PM B Cell Responses and Broadly-Neutralizing Antibodies: Trials and Tribulations (Joint)
  Marina F. Caskey, Rockefeller University
Combined Immunotherapy with IL-15 Agonists and Broadly-Neutralizing Antibodies
 
  Paula M. Cannon, University of Southern California, Keck School of Medicine
Engineering B Cells as in vivo bnAb Factories
 
  William Schief, The Scripps Research and IAVI
Combining Germline Targeting Approaches Across Diverse bNAb Epitopes
 
  Short Talk(s) Chosen from Abstracts
 
6:45–7:00 PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
7:00–8:00 PM Social Hour with Dinner
8:00–11:00 PM Cash Bar
8:00–11:00 PM Entertainment
Monday, April 20, 2026
12:00–11:59 PM Departure